By Scientia Professor Matthew Colm Kiernan

Journal articles

Huynh W; Simon NG; Grosskreutz J; Turner MR; Vucic S; Kiernan MC, 2016, 'Assessment of the upper motor neuron in amyotrophic lateral sclerosis', Clinical Neurophysiology, 127, pp. 2643 - 2660, http://dx.doi.org/10.1016/j.clinph.2016.04.025

Geevasinga N; Loy CT; Menon P; de Carvalho M; Swash M; Schrooten M; Van Damme P; Gawel M; Sonoo M; Higashihara M; Noto YI; Kuwabara S; Kiernan MC; Macaskill P; Vucic S, 2016, 'Awaji criteria improves the diagnostic sensitivity in amyotrophic lateral sclerosis: A systematic review using individual patient data', Clinical Neurophysiology, 127, pp. 2684 - 2691, http://dx.doi.org/10.1016/j.clinph.2016.04.005

Arnold R; Pussell BA; Kiernan MC; Krishnan AV, 2016, 'Comparative study to evaluate the effects of peritoneal and hemodialysis on peripheral nerve function', Muscle and Nerve, 54, pp. 58 - 64, http://dx.doi.org/10.1002/mus.25016

Huynh W; Pickering H; Howells J; Murray J; Cormack C; Lin CSY; Vucic S; Kiernan MC; Krishnan AV, 2016, 'Effect of fampridine on axonal excitability in multiple sclerosis', Clinical Neurophysiology, 127, pp. 2636 - 2642, http://dx.doi.org/10.1016/j.clinph.2016.04.010

Barnett MH; Mathey E; Kiernan MC; Pollard JD, 2016, 'Axonal damage in central and peripheral nervous system inflammatory demyelinating diseases: Common and divergent pathways of tissue damage', Current Opinion in Neurology, 29, pp. 213 - 221, http://dx.doi.org/10.1097/WCO.0000000000000334

Hornberger M; Kiernan MC, 2016, 'Emergence of an imaging biomarker for amyotrophic lateral sclerosis: Is the end point near?', Journal of Neurology, Neurosurgery and Psychiatry, 87, pp. 569, http://dx.doi.org/10.1136/jnnp-2015-312882

Shibuya K; Park SB; Geevasinga N; Huynh W; Simon NG; Menon P; Howells J; Vucic S; Kiernan MC, 2016, 'Threshold tracking transcranial magnetic stimulation: Effects of age and gender on motor cortical function', Clinical Neurophysiology, 127, pp. 2355 - 2361, http://dx.doi.org/10.1016/j.clinph.2016.03.009

Devine MS; Ballard E; Orourke P; Kiernan MC; McCombe PA; Henderson RD, 2016, 'Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17, pp. 184 - 190, http://dx.doi.org/10.3109/21678421.2015.1125502

Murray L; Butow PN; White K; Kiernan MC; D'Abrew N; Herz H, 2016, 'Advance care planning in motor neuron disease: A qualitative study of caregiver perspectives', Palliative Medicine, 30, pp. 471 - 478, http://dx.doi.org/10.1177/0269216315613902

Caga J; Turner MR; Hsieh S; Ahmed RM; Devenney E; Ramsey E; Zoing MC; Mioshi E; Kiernan MC, 2016, 'Apathy is associated with poor prognosis in amyotrophic lateral sclerosis', European Journal of Neurology, 23, pp. 891 - 897, http://dx.doi.org/10.1111/ene.12959

De Silva D; Hsieh S; Caga J; Leslie FVC; Kiernan MC; Hodges JR; Mioshi E; Burrell JR, 2016, 'Motor function and behaviour across the ALS-FTD spectrum', Acta Neurologica Scandinavica, 133, pp. 367 - 372, http://dx.doi.org/10.1111/ane.12471

Kiernan MS; Katz JN, 2016, 'Operating in the Dark When Is Surgery Necessary for Left Ventricular Assist Device Hemolysis?', CIRCULATION-HEART FAILURE, 9, http://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003141

Kamminga J; Leslie FVC; Hsieh S; Caga J; Mioshi E; Hornberger M; Ballard KJ; Kiernan MC; Hodges JR; Burrell JR, 2016, 'Syntactic comprehension deficits across the FTD-ALS continuum', Neurobiology of Aging, 41, pp. 11 - 18, http://dx.doi.org/10.1016/j.neurobiolaging.2016.02.002

Bae JS; Ferguson M; Tan R; Mioshi E; Simon N; Burrell J; Vucic S; Hodges JR; Kiernan MC; Hornberger M, 2016, 'Dissociation of structural and functional integrities of the motor system in amyotrophic lateral sclerosis and behavioral-variant frontotemporal dementia', Journal of Clinical Neurology (Korea), 12, pp. 209 - 217, http://dx.doi.org/10.3988/jcn.2016.12.2.209

Simon NG; Lagopoulos J; Gallagher T; Kliot M; Kiernan MC, 2016, 'Peripheral nerve diffusion tensor imaging is reliable and reproducible', Journal of Magnetic Resonance Imaging, 43, pp. 962 - 969, http://dx.doi.org/10.1002/jmri.25056

Ahmed RM; Irish M; Henning E; Dermody N; Bartley L; Kiernan MC; Piguet O; Farooqi S; Hodges JR, 2016, 'Assessment of eating behavior disturbance and associated neural networks in frontotemporal dementia', JAMA Neurology, 73, pp. 282 - 290, http://dx.doi.org/10.1001/jamaneurol.2015.4478

Huynh W; Vucic S; Krishnan AV; Lin CSY; Kiernan MC, 2016, 'Exploring the evolution of cortical excitability following acute stroke', Neurorehabilitation and Neural Repair, 30, pp. 244 - 257, http://dx.doi.org/10.1177/1545968315593804

Grieve SM; Menon P; Korgaonkar MS; Gomes L; Foster S; Kiernan MC; Vucic S, 2016, 'Potential structural and functional biomarkers of upper motor neuron dysfunction in ALS', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17, pp. 85 - 92, http://dx.doi.org/10.3109/21678421.2015.1074707

Tan RH; Kril JJ; McGinley C; Hassani M; Masuda-Suzukake M; Hasegawa M; Mito R; Kiernan MC; Halliday GM, 2016, 'Cerebellar neuronal loss in amyotrophic lateral sclerosis cases with ATXN2 intermediate repeat expansions', Annals of Neurology, 79, pp. 295 - 305, http://dx.doi.org/10.1002/ana.24565

Shahrizaila N; Sobue G; Kuwabara S; Kim SH; Birks C; Fan DS; Bae JS; Hu CJ; Gourie-Devi M; Noto Y; Shibuya K; Goh KJ; Kaji R; Tsai CP; Cui L; Talman P; Henderson RD; Vucic S; Kiernan MC, 2016, 'Amyotrophic lateral sclerosis and motor neuron syndromes in Asia', Journal of Neurology, Neurosurgery and Psychiatry, 87, pp. 821 - 830, http://dx.doi.org/10.1136/jnnp-2015-312751

Kiernan MC, 2016, '35,000 Days on Earth', Journal of Neurology, Neurosurgery and Psychiatry, 87, pp. 1 - 2, http://dx.doi.org/10.1136/jnnp-2015-312686

Garg N; Yuki N; Park SB; Barnett MH; Kiernan MC, 2016, 'Acute bulbar, neck and limb weakness with monospecific anti-GT1a antibody: A rare localized subtype of Guillain-Barré sydnrome', Muscle and Nerve, 53, pp. 143 - 146, http://dx.doi.org/10.1002/mus.24935

Ahmed RM; Irish M; Piguet O; Halliday GM; Ittner LM; Farooqi S; Hodges JR; Kiernan MC, 2016, 'Amyotrophic lateral sclerosis and frontotemporal dementia: distinct and overlapping changes in eating behaviour and metabolism', The Lancet Neurology, 15, pp. 332 - 342, http://dx.doi.org/10.1016/S1474-4422(15)00380-4

Hsieh S; Caga J; Leslie FVC; Shibata M; Daveson N; Foxe D; Ramsey E; Lillo P; Ahmed RM; Devenney E; Burrell JR; Hodges JR; Kiernan MC; Mioshi E, 2016, 'Cognitive and Behavioral Symptoms in ALSFTD', Journal of Geriatric Psychiatry and Neurology, 29, pp. 3 - 10, http://dx.doi.org/10.1177/0891988715598232

Simon NG; Kiernan MC, 2016, 'Diaphragm ultrasound in amyotrophic lateral sclerosis and other neuromuscular disorders', Clinical Neurophysiology, 127, pp. 28 - 30, http://dx.doi.org/10.1016/j.clinph.2015.04.066

Talman P; Duong T; Vucic S; Mathers S; Venkatesh S; Henderson R; Rowe D; Schultz D; Edis R; Needham M; Macdonnell R; McCombe P; Birks C; Kiernan M, 2016, 'Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort', BMJ Open, 6, http://dx.doi.org/10.1136/BMJOPEN-2016-012054

Menezes MP; Farrar MA; Webster R; Antony J; O'Brien K; Ouvrier R; Kiernan MC; Burns J; Vucic S, 2016, 'Pathophysiology of motor dysfunction in a childhood motor neuron disease caused by mutations in the riboflavin transporter', Clinical Neurophysiology, 127, pp. 911 - 918, http://dx.doi.org/10.1016/j.clinph.2015.05.012

Dharmadasa T; Matamala JM; Kiernan MC, 2016, 'Treatment approaches in motor neurone disease', Current Opinion in Neurology, 29, pp. 581 - 591, http://dx.doi.org/10.1097/WCO.0000000000000369

Garg N; Park SB; Pollard JD; Yiannikas C; Kiernan MC, 2016, '10. Neurophysiological profile of multifocal motor neuropathy', Clinical Neurophysiology, 127, pp. e13 - e13, http://dx.doi.org/10.1016/j.clinph.2015.11.030

Geevasinga N; Menon P; Loy C; Yiannikas C; Simon NG; Kiernan MC; Vucic S, 2016, '11. Revisiting early diagnosis in ALS', Clinical Neurophysiology, 127, pp. e13 - e14, http://dx.doi.org/10.1016/j.clinph.2015.11.031

Geevasinga N; Menon P; Ng K; Kiernan MC; Vucic S, 2016, '12. Riluzole exerts short-term effects on cortical hyperexcitability in sporadic ALS', Clinical Neurophysiology, 127, pp. e14 - e14, http://dx.doi.org/10.1016/j.clinph.2015.11.032

Howells J; Park SB; Burke D; Kiernan MC, 2016, '18. Dysfunctional properties of single motor units in ALS', Clinical Neurophysiology, 127, pp. e16 - e16, http://dx.doi.org/10.1016/j.clinph.2015.11.038

J. van den Bos MA; Menon P; Geevasinga N; Kiernan MC; Vucic S, 2016, '19. Cortical hyperexcitability in ALS: A heterogeneous process', Clinical Neurophysiology, 127, pp. e17 - e17, http://dx.doi.org/10.1016/j.clinph.2015.11.039

Farrar MA; Vucic S; Nicholson G; Kiernan MC, 2016, '3. Cortical dysfunction in Machado–Jospeh disease', Clinical Neurophysiology, 127, pp. e11 - e11, http://dx.doi.org/10.1016/j.clinph.2015.11.023

Timmins HC; Cheah BC; Lin CSY; Vucic S; Kiernan MC; Park SB, 2016, '5. Neurophysiological measures correlate with functional outcomes in ALS', Clinical Neurophysiology, 127, pp. e11 - e11, http://dx.doi.org/10.1016/j.clinph.2015.11.025

Shibuya K; Park SB; Geevasinga N; Huynh W; Simon NG; Menon P; Howells J; Garg N; Noto Y-I; Iwai Y; Nicholson GA; Vucic S; Kuwabara S; Kiernan MC, 2016, '7. Pathophysiological basis of motor neuronal hyperexcitability in amyotrophic lateral sclerosis', Clinical Neurophysiology, 127, pp. e12 - e12, http://dx.doi.org/10.1016/j.clinph.2015.11.027

Hornberger M; Kiernan MC, 2016, 'Emergence of an imaging biomarker for amyotrophic lateral sclerosis: is the end point near?', Journal of Neurology, Neurosurgery & Psychiatry, 87, pp. 569 - 569, http://dx.doi.org/10.1136/jnnp-2015-312882

Kwai NCG; Arnold R; Poynten AM; Howells J; Kiernan MC; Lin CSY; Krishnan AV, 2016, 'In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes', Clinical Neurophysiology, 127, pp. 1700 - 1706, http://dx.doi.org/10.1016/j.clinph.2015.11.047

Park SB; Vucic S; Cheah BC; Lin CSY; Kirby A; Mann KP; Zoing MC; Winhammar J; Kiernan MC, 2015, 'Flecainide in Amyotrophic Lateral Sclerosis as a Neuroprotective Strategy (FANS): A Randomized Placebo-Controlled Trial', EBioMedicine, 2, pp. 1916 - 1922, http://dx.doi.org/10.1016/j.ebiom.2015.11.022

Arnold R; Huynh W; Kiernan MC; Krishnan AV, 2015, 'Ion channel modulation as a therapeutic approach in multiple sclerosis', Current Medicinal Chemistry, 22, pp. 4366 - 4378, http://dx.doi.org/10.2174/0929867322666151029104452

Lu R; Kiernan MC; Murray A; Rosner MH; Ronco C, 2015, 'Kidney-brain crosstalk in the acute and chronic setting', Nature Reviews Nephrology, 11, pp. 707 - 719, http://dx.doi.org/10.1038/nrneph.2015.131

Kiernan MC; Turner MR, 2015, 'Lou Gehrig and the ALS split hand', Neurology, 85, pp. 1995, http://dx.doi.org/10.1212/WNL.0000000000002172

Devenney E; Bartley L; Hoon C; O'Callaghan C; Kumfor F; Hornberger M; Kwok JB; Halliday GM; Kiernan MC; Piguet O; Hodges JR, 2015, 'Progression in behavioral variant frontotemporal dementia: A longitudinal study', JAMA Neurology, 72, pp. 1501 - 1509, http://dx.doi.org/10.1001/jamaneurol.2015.2061

Geevasinga N; Menon P; Nicholson GA; Ng K; Howells J; Kril JJ; Yiannikas C; Kiernan MC; Vucic S, 2015, 'Cortical function in asymptomatic carriers and patients with C9Orf72 amyotrophic lateral sclerosis', JAMA Neurology, 72, pp. 1268 - 1274, http://dx.doi.org/10.1001/jamaneurol.2015.1872

Sillence KA; Roberts LA; Hollands HJ; Thompson HP; Kiernan M; Madgett TE; Welch CR; Avent ND, 2015, 'Fetal Sex and RHD Genotyping with Digital PCR Demonstrates Greater Sensitivity than Real-time PCR', CLINICAL CHEMISTRY, 61, pp. 1399 - 1407, http://dx.doi.org/10.1373/clinchem.2015.239137

Simon NG; Kiernan MC, 2015, 'Precise correlation between structural and electrophysiological disturbances in MADSAM neuropathy', Neuromuscular Disorders, 25, pp. 904 - 907, http://dx.doi.org/10.1016/j.nmd.2015.07.012

Ke YD; van Hummel A; Stevens CH; Gladbach A; Ippati S; Bi M; Lee WS; Krüger S; van der Hoven J; Volkerling A; Bongers A; Halliday G; Haass NK; Kiernan M; Delerue F; Ittner LM, 2015, 'Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS', Acta Neuropathologica, 130, pp. 661 - 678, http://dx.doi.org/10.1007/s00401-015-1486-0

Ahmed RM; Latheef S; Bartley L; Irish M; Halliday GM; Kiernan MC; Hodges JR; Piguet O, 2015, 'Eating behavior in frontotemporal dementia', Neurology, 85, pp. 1310 - 1317, http://dx.doi.org/10.1212/WNL.0000000000002018

Linnane B; Kearse L; O'Connell NH; Fenton J; Kiernan MG; Dunne CP, 2015, 'A case of failed eradication of cystic fibrosis-related sinus colonisation by Pseudomonas aeruginosa', BMC PULMONARY MEDICINE, 15, http://dx.doi.org/10.1186/s12890-015-0113-0

Hogden A; Greenfield D; Nugus P; Kiernan MCS, 2015, 'Development of a model to guide decision making in amyotrophic lateral sclerosis multidisciplinary care', Health Expectations, 18, pp. 1769 - 1782, http://dx.doi.org/10.1111/hex.12169

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