Improvements in childhood cancer treatments have lead to a survival rate of more than 80%, but 2/3 of the survivors further develop at least one severe complication, notably metabolic disorders. Radiation therapy seems to be the most prominent risk factor.

Mitochondria are the major site for fuel oxidation in cells and strategies that stimulate mitochondria to burn more calories may prove beneficial for preventing obesity and insulin resistance.

There is a clear relationship between excess intake of dietary fat (particularly animal-based fats such as lard) and the development of obesity and insulin resistance.

Cancer cells reprogram their metabolism to use fuel (fat, protein and glucose) in a different way to normal cells. This adaptation is thought to allow cancer cells to make the building blocks (proteins, DNA, lipids) they need to grow and divide rapidly.

Excess fat in the diet typically leads to weight gain and inappropriate deposition of lipid in organs such as liver and skeletal muscle.

UNSW has been involved in researching the economics of CCS since the year 2000 and its CCS economics group is a leader in this field.

Self-assembled gels are a new class of materials that have been shown to have applications in tissue engineering and drug delivery.

Peripheral nerve injury often results in persistent and debilitating neuropathic pain. My overall objective is to understand the immunological mechanisms responsible for such pain.

Electroconvulsive therapy (ECT) is a highly effective treatment for depression, used in Australia and throughout the world to treat severe depression that has not responded to other treatments.

Unlimited access to palatable high fat foods, in conjunction with a sedentary life style, has led to increased obesity. Exactly what mechanisms drive over consumption of energy rich foods and override mechanisms that normally regulate body weight?

This project will provide important information regarding the pharmacological mechanisms by which NPY acts to suppress seizures in animal models of epilepsy. It will provide strategies regarding potential new treatments of absence epilepsy.

This project will produce an easy-to-use prototype system for guiding blind and visually impaired (BVI) people both indoors and outdoors and delivering location based information.

To achieve high economical efficiency, modern chemical plants are becoming increasingly complex, to an extent that cannot be effectively managed by existing process modelling and control techniques.

The aims of this research are to assess the effects of immune modulation by inducing immune tolerance and manipulating regulatory T cells on pain behaviours following nervous system injury.

The actin cytoskeleton has long been known to be a key regulator of cell proliferation linking biochemical sensing of the environment with cell cycle progression.

Fouling reduces throughput and productivity of membrane systems and as such increases operating costs and reduces profitability of water treatment industries. This work aims to reduce fouling by reducing the amount of solute at a membrane surface by destabilizing flow control.

We have recently built the first protein 'methylation network' for any species. This project will study the dynamics of this network during the cell cycle and will identify protein complexes which have methylation-associated interactions.

The aim of the project is to reveal the mechanisms of the stabilisation of lifted jet flames in hot oxidiser. Such flames occur in several important combustion devices, notably diesel engines.

The project will develop a robust approach to use maximum entropy methods to model likelihood functions for a Bayesian analysis of chemical data.