Select Publications

Journal articles

Wake H; Moorhouse AJ; Jinno S; Kohsaka S; Nabekura J, 2009, 'Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals', Journal of Neuroscience, 29, pp. 3974 - 3980

Sugiharto S; Lewis TM; Moorhouse AJ; Schofield PR; Barry PH, 2008, 'Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels', Biophysical Journal, 95, pp. 4698 - 4715, http://dx.doi.org/10.1529/biophysj.107.125690

Park E; Choi I; Cho J; Nakamura M; Lee J; Lee M; Choi B; Moorhouse AJ; Jang I, 2008, 'Zinc modulation of glycine receptors in acutely isolated rat CA3 neurons', Life Sciences, 83, pp. 149 - 154, http://dx.doi.org/10.1016/j.lfs.2008.04.024

Wake H; Watanabe M; Moorhouse AJ; Kanematsu T; Horibe S; Matsukawa N; Asai K; Ojika K; Hirata M; Nabekura J, 2007, 'Early changes in KCC2 phosphorylation in response to neuronal stress result in functional downregulation', Journal of Neuroscience, 27, pp. 1642 - 1650

Qu W; Moorhouse AJ; Chandra M; Pierce KD; Lewis TM; Barry PH, 2006, 'A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channel', Journal of General Physiology, 127, pp. 375 - 389, http://dx.doi.org/10.1085/jgp.200509378

Qu W; Moorhouse AJ; Lewis TM; Pierce KD; Barry PH, 2005, 'Mutation of the pore glutamate affects both cytoplasmic and external dequalinium block in the rat olfactory CNGA2 channel', European Biophysics Journal with Biophysics Letters, 34, pp. 442 - 453

Moorhouse AJ; Li S; Vickery RM; Hill MA; Morley JW, 2004, 'A patch-clamp investigation of membrane currents in a novel mammalian retinal ganglion cell line', Brain Research, 1003, pp. 205 - 208

Carland JE; Moorhouse AJ; Barry PH; Johnston G; Chebib M, 2004, 'Charged residues at the 2 ` position of human GABA(c) rho 1 receptorsinvert ion selectivity and influence open state probability', The Journal of Biological Chemistry, 279, pp. 54153 - 54160

Katsurabayashi S; Kubota H; Moorhouse AJ; Akaike N, 2004, 'Differential modulation of evoked and spontaneous glycine release fromrat spinal cord glycinergic terminals by the cyclic AMP/protein kinaseA transduction cascade', Journal of Neurochemistry, 91, pp. 657 - 666

Keramidas A; Moorhouse AJ; Schofield PR; Barry PH, 2004, 'Ligand-gated ion channels: mechanisms underlying ion selectivity', Progress in Biophysics and Molecular Biology, 86, pp. 161 - 204

Kubota H; Katsurabayashi S; Moorhouse AJ; Murakami N; Koga H; Akaike N, 2003, 'GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert', Journal of Physiology, 551, pp. 263 - 276, http://dx.doi.org/10.1113/jphysiol.2003.046524

Jeong H; Jan I; Moorhouse AJ; Akaike N, 2003, 'Activation of presynaptic glycine receptors facilitate glycine release from presynaptic terminals synapsing onto rat spinal sacral dorsal commissural nucleus nerons', The Journal of Physiology, 550, pp. 373 - 383

Kubota H; Katsurabayashi S; Moorhouse AJ; Murakami N; Koga H; Akaike N, 2003, 'GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert', The Journal of Physiology, 551, pp. 263 - 276

Akaike N; Moorhouse AJ, 2003, 'Techniques: Applications of the Nerve - bouton preparation in Neuropharmacology', Trends in Pharmacological Sciences, 24, pp. 44 - 47

Lee DJ; Keramidas A; Moorhouse AJ; Schofield PR; Barry PH, 2003, 'The contribution of P250 (P-2`D) to ion selectivity and pore diameter in the human glycine receptor.', Neuroscience Letters, 351, pp. 196 - 200

Keramidas A; Moorhouse AJ; Pierce K; Schofield PR; Barry PH; Schofield P, 2002, 'Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion charge selectivity', Journal of General Physiology, 119, pp. 393 - 410, http://dx.doi.org/10.1085/jgp.20028552

Moorhouse AJ; Keramidas A; Zaikine A; Zaykin A; Schofield PR; Barry PH; Schofield P, 2002, 'Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels', Journal of General Physiology, 119, pp. 411 - 425, http://dx.doi.org/10.1085/jgp.20028553

Kaur R; Zhu XO; Moorhouse AJ; Barry PH, 2001, 'Ip3-gated channels and their occurrence relative to CNG channels in the soma and dendritic knob of rat olfactory receptor neurons', Journal of Membrane Biology, 181, pp. 91 - 105, http://dx.doi.org/10.1007/s00232-001-0013-5

Qu W; Moorhouse AJ; Cunningham AM; Barry PH, 2001, 'Anomalous Mole-Fraction Effects in Recombinat & Native Cyclic Nucleotide-Gated Channels in Rat Olfactory Receptor Neurons', Proceedings of the Royal Society of London Series B - Biological Sciences, pp. 1395 - 1403

Kaur R; Zhu X; Moorhouse AJ; Barry PH, 2001, 'IP3-Gated Channels and their Occurrence Relative to CNG Channels in the Soma and Dendritic Knob of Rat Olfactory Receptor Neurons', Journal of Membrane Biology, 181, pp. 91 - 105

Qu W; Zhu X; Moorhouse AJ; Bieri S; Cunningham AM, 2000, 'Ion permeation and selectivity of wild-type recombinant rat (CNG (rOCNC1) chanels expressed in HEK293 cells', Journal of Membrane Biology, 178, pp. 137 - 150

Keramidas A; Moorhouse AJ; French C; Schofield PR; Barry PH, 2000, 'M2 pore mutations convert the glycine receptor channel from being anion to cation selective', Biophysical Journal, 78, pp. 247 - 259

Keramidas A; Moorhouse AJ; French CD; Schofield PR; Barry PH, 2000, 'M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective', Biophysical Journal, pp. 247 - 259

Qu W; Moorhouse AJ; Rajendra S; Barry PH, 2000, 'Very negative potential for half-inactivation of and effects of anions on voltage-dependent sodium currents in acutely isolated rat olfactory receptor neurons', Journal of Membrane Biology, 175, pp. 123 - 138

Smith PR; Proks P; Moorhouse AJ, 1999, 'Direct effects of tolutamide on mitochondrial function, intracellular Ca2+ and exocytosis in pancreatic beta-cells', Pflugers Archiv - European Journal of Physiology, pp. 577 - 588

Barry PH; Schofield PR; Moorhouse AJ, 1999, 'Glycine receptors: What gets in and why', Clinical and Experimental Pharmacology and Physiology, pp. 935 - 936

Barry PH; Schofield PR; Moorhouse AJ, 1999, 'Glycine receptors: What gets in and why?', Clinical and Experimental Pharmacology and Physiology, pp. 935 - 936

Keramidas A; Kuhlmann L; Moorhouse AJ; Barry PH, 1999, 'Measurement of the limiting equivalent conductivities and mobilities of the most prevalent ionic species of EGTA (EGTA2-and EGTA3-) for use in electrophysiological experiments', Journal of Neuroscience Methods, pp. 41 - 47

Moorhouse AJ; Jacques P; Barry PH; Schofield PR, 1999, 'The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating', Molecular Pharmacology, pp. 386 - 395

Proks P; Moorhouse A; Smith PA; Ashcroft FM, 1996, 'Protein kinase C does not influence the tolbutamide sensitivity of K-ATP currents', DIABETOLOGIA, 39, pp. 105 - 105, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996VA49300106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ämmälä C; Moorhouse A; Gribble F; Ashfield R; Proks P; Smith PA; Sakura H; Coles B; Ashcroft SJH; Ashcroft FM, 1996, 'Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels', Nature, 379, pp. 545 - 548, http://dx.doi.org/10.1038/379545a0

Tucker SJ; Pessia M; Moorhouse AJ; Gribble F; Ashcroft FM; Maylie J; Adelman JP, 1996, 'Heteromeric channel formation and Ca2+-free media reduce the toxic effect of the weaver K 3.2 allele', FEBS Letters, pp. 253 - 257

Ammala C; Moorhouse AJ; Ashcroft FM, 1996, 'The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying Kir6.1 expressed in human embroyonic kidney cells', The Journal of Physiology, pp. 709 - 714

MOORHOUSE AJ; SPENCE I, 1995, 'SYNAPTIC TRANSMISSION, HYPOXIA AND ADENOSINE IN THE ISOLATED NEONATAL RAT SPINAL-CORD', JOURNAL OF PHYSIOLOGY-LONDON, 489P, pp. P23 - P23, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TH85400029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers

Kim YS; Moorhouse AJ; Bertrand PP; Klugmann M; Housley GD, 2013, 'Alternative splicing of Canonical Transient Receptor Potential type 3 (TRPC3) ion channel expression in the human brain', in Journal of Neurological Sciences vol 333, Elsevier, Vienna, Austria, pp. e654, presented at World Congress of Neurology, Vienna, Austria, 21 September 2013 - 26 September 2013, http://www.journals.elsevier.com/journal-of-the-neurological-sciences/

Moorhouse AJ; Sugiharto S; Carland JE; Lewis TM; Barry PH, 2012, 'Anion selectivity and counter-ion cation permeation in glycine receptor channels.', in FASEB JOURNAL Volume: 26 Published: APR 2012, American Physiology Society, Abs#, 901.2., presented at Experimental Biology Meeting

Barry PH; Lewis TM; Moorhouse AJ, 2011, 'An improved method, with theoretical analyses, for the simple experimental measurement of liquid junction potentials', Wollongong, presented at BioPhysChem 2011, a joint meeting of the RACI Physical Chemistry Division and the Australian Society for Biophysics,, Wollongong

Wake H; Moorhouse AJ; Jinno S; Kohsaka S; Nabekura J, 2008, 'Resting microglia directly monitor synapses in vivo and determine the fate of ischemic terminals', in Neuroscience Research, Elsevier Sci Ireland Ltd, Clare, Ireland, pp. S152 - S152, presented at Neuroscience Research

Conference Posters

Barry PH; Lewis TM; Moorhouse AJ, 2013, 'Experimental and theoretical validation of calculated liquid junction potentials in monovalent ion solutions and effects of divalent ions', RMIT, Melbourne, presented at 37th Annual Meeting of the Australian Society for Biophysics, RMIT, Melbourne, 24 November 2013 - 27 November 2013

Khoshaba ; Power J; Moorhouse AJ, 2013, 'Quantifying KCC2 activity in isolated hippocampal neurons using fluorescent imaging. Poster presentation', Canberra, presented at Gage Conference on Ion Channels and Transporters, Canberra, 17 April 2013 - 20 April 2013

Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'Do divalent cations increase the anion-cation permeability in glycine receptor channels, even with initial offset and activity corrections?', Japan, pp. 393 - 393, presented at 36th International Congress of Physiological Sciences, Kyoto, Japan, 27 July 2009 - 01 August 2009

Moorhouse A; Carland JE; Cooper MA; Sugiharto S; Jeong H-J; Lewis TM; Barry PH; Peters JA; Lambert JJ, 2009, 'Molecular determinants of ion permeation in glycine receptor-channels: characterising charged residues in the intracellular M3-M4 loop', Kyoto, Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Societies, Kyoto, Japan, 27 July 2009 - 01 August 2009

Conference Presentations

Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Online peer assessment: Challenges, triumphs and lessons learnt during COVID-19', presented at UNSW Medicine & Health Education Forum, UNSW Sydney, 04 December 2020

Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Our challenges and triumphs with online peer assessment in a fully remote course.', presented at Australian Physiological Society Education Forum, 25 November 2020

Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Student Peer Assessment Using Moodle Workshop: Challenges in a COVID-19 world.', presented at UNSW Learning & Teaching Forum, 19 November 2020 - 20 November 2020

Moorhouse AJ, 2013, 'Upregulating KCC2 enhances neuronal inhibition. Oral presentation, Gage Conference on Ion Channels and Transporters', Canberra,, 17 April 2013 - 20 April 2013

Barry PH; Lewis TM; Moorhouse AJ, 2011, 'An improved method, with theoretical analysis, for the simple experimental measurement of liquid junction potentials', presented at Joint ASB-BioPhysChem 2011 Conference, University of Wollongong, NSW, Australia, 03 December 2011 - 06 December 2011

Barry PH; Sugiharto S; Carland JE; Moorhouse AJ; Lewis TM, 2009, 'Permeability measurements in anion channels: effects of divalent cations, liquid junction potentials and offsets', presented at 33rd Annual Meeting of the Australian Society for Biophysics, Ballarat, NSW, Australia, 29 November 2009

Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'The lack of certain activity corrections and initial offset corrections can produce erroneous anion-cation permeability ratios in GlyR channels', presented at Curtin Conference, RMIT, Melbourne, VIC, 15 April 2009 - 17 April 2009

Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'Charged residues in the intracellular loop affect the conductance of glycine α1 receptors', presented at Ligand Gated Ion Channels: 18th Neuropharmacology Conference, Washington DC, USA, 12 November 2008 - 14 November 2008


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