Select Publications

Book Chapters

Nissen NI; Karsdal MA; Cox TR; Willumsen N, 2023, 'The roles of collagens and fibroblasts in cancer', in Biochemistry of Collagens, Laminins and Elastin: Structure, Function and Biomarkers, Third Edition, pp. 419 - 434, http://dx.doi.org/10.1016/B978-0-443-15617-5.00029-9

Ramchandani D; El Rayes TP; Gao D; Altorki NK; Cox TR; Erler JT; Mittal V, 2022, 'Regulation of Tumor Progression and Metastasis by Bone Marrow-Derived Microenvironments', in Biomarkers of the Tumor Microenvironment, Second Edition, pp. 245 - 266, http://dx.doi.org/10.1007/978-3-030-98950-7_14

Filipe EC; Parker AL; Cadell AL; Major G; Croucher DR; Cox TR, 2021, 'In Vitro 3D Models of Tunable Stiffness', in Metastasis: Methods and Protocols, pp. 27 - 42, http://dx.doi.org/10.1007/978-1-0716-1350-4_3

Papanicolaou M; Cox TR, 2021, 'Extracellular Matrix (ECM)', in Encyclopedia of Molecular Pharmacology, Springer International Publishing, pp. 643 - 650, http://dx.doi.org/10.1007/978-3-030-57401-7_5691

Papanicolaou M; Cox TR, 2020, 'Extracellular Matrix (ECM)', in Encyclopedia of Molecular Pharmacology, Springer International Publishing, pp. 1 - 8, http://dx.doi.org/10.1007/978-3-030-21573-6_5691-1

El Rayes T; Gao D; Altorki NK; Cox TR; Erler JT; Mittal V, 2017, 'Regulation of tumor progression and metastasis by bone marrow-derived microenvironments', in Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications, Springer, pp. 303 - 328, http://dx.doi.org/10.1007/978-3-319-39147-2_13

Cox TR; Erler JT, 2013, 'Remodelling of the extracellular matrix: Implications for cancer', in Cell and Molecular Biology of Breast Cancer, pp. 65 - 90, http://dx.doi.org/10.1007/978-1-62703-634-4_4

Journal articles

Vettori L; Tran HA; Mahmodi H; Filipe EC; Wyllie K; Liu Chung Ming C; Cox TR; Tipper J; Kabakova IV; Rnjak-Kovacina J; Gentile C, 2024, 'Silk fibroin increases the elasticity of alginate-gelatin hydrogels and regulates cardiac cell contractile function in cardiac bioinks', Biofabrication, 16, http://dx.doi.org/10.1088/1758-5090/ad4f1b

Pajic M; McLean B; Fajardo DC; Porazinski S; Upton DH; Schuhmacher D; Istadi A; Cox T; Timpson P; Wilcock DJ; Anderson KJ; Mason H; Guisot NE; Jones CD; Phillips C; Armer R, 2024, 'Abstract 720: Combining zelasudil, a small molecule ROCK2 inhibitor, with chemotherapy or immunotherapy improves response in preclinical models of pancreatic cancer', Cancer Research, 84, pp. 720 - 720, http://dx.doi.org/10.1158/1538-7445.am2024-720

Mok ETY; Chitty JL; Cox TR, 2024, 'miRNAs in pancreatic cancer progression and metastasis', Clinical and Experimental Metastasis, http://dx.doi.org/10.1007/s10585-023-10256-0

Thorlacius-Ussing J; Jensen C; Nissen NI; Cox TR; Kalluri R; Karsdal M; Willumsen N, 2024, 'The collagen landscape in cancer: profiling collagens in tumors and in circulation reveals novel markers of cancer-associated fibroblast subtypes', Journal of Pathology, 262, pp. 22 - 36, http://dx.doi.org/10.1002/path.6207

Filipe EC; Velayuthar S; Philp A; Nobis M; Latham SL; Parker AL; Murphy KJ; Wyllie K; Major GS; Contreras O; Mok ETY; Enriquez RF; McGowan S; Feher K; Quek LE; Hancock SE; Yam M; Tran E; Setargew YFI; Skhinas JN; Chitty JL; Phimmachanh M; Han JZR; Cadell AL; Papanicolaou M; Mahmodi H; Kiedik B; Junankar S; Ross SE; Lam N; Coulson R; Yang J; Zaratzian A; Da Silva AM; Tayao M; Chin IL; Cazet A; Kansara M; Segara D; Parker A; Hoy AJ; Harvey RP; Bogdanovic O; Timpson P; Croucher DR; Lim E; Swarbrick A; Holst J; Turner N; Choi YS; Kabakova IV; Philp A; Cox TR, 2024, 'Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism', Advanced Science, http://dx.doi.org/10.1002/advs.202307963

Williams C; Noll J; Harnas D; Parkinson H; Hewett D; Wyllie K; Cox T; Zannettino A; Vandyke K; Panagopoulos V, 2023, 'Targeted Inhibition of Myeloperoxidase (MPO): A New Therapeutic Strategy for the Treatment of Multiple Myeloma', Blood, 142, pp. 3319 - 3319, http://dx.doi.org/10.1182/blood-2023-179196

Wyllie K; Panagopoulos V; Cox TR, 2023, 'The role of peroxidasin in solid cancer progression', Biochemical Society Transactions, 51, pp. 1881 - 1895, http://dx.doi.org/10.1042/BST20230018

Chitty JL; Yam M; Perryman L; Parker AL; Skhinas JN; Setargew YFI; Mok ETY; Tran E; Grant RD; Latham SL; Pereira BA; Ritchie SC; Murphy KJ; Trpceski M; Findlay AD; Melenec P; Filipe EC; Nadalini A; Velayuthar S; Major G; Wyllie K; Papanicolaou M; Ratnaseelan S; Phillips PA; Sharbeen G; Youkhana J; Russo A; Blackwell A; Hastings JF; Lucas MC; Chambers CR; Reed DA; Stoehr J; Vennin C; Pidsley R; Zaratzian A; Da Silva AM; Tayao M; Charlton B; Herrmann D; Nobis M; Clark SJ; Biankin AV; Johns AL; Croucher DR; Nagrial A; Gill AJ; Grimmond SM; Chantrill LA; Chou A; Dwarte T; Metcalf XL; Jeong G; Kenyon L; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; McLeo D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J, 2023, 'A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer', Nature Cancer, 4, pp. 1326 - 1344, http://dx.doi.org/10.1038/s43018-023-00614-y

Widodo SS; Dinevska M; Cuzcano L; Papanicolaou M; Cox TR; Stylli SS; Mantamadiotis T, 2023, 'Spatial analysis of the metastatic brain tumor immune and extracellular matrix microenvironment', Advances in Cancer Biology - Metastasis, 7, http://dx.doi.org/10.1016/j.adcanc.2023.100096

Hastings JF; Latham SL; Kamili A; Wheatley MS; Han JZR; Wong-Erasmus M; Phimmachanh M; Nobis M; Pantarelli C; Cadell AL; O’Donnell YEI; Leong KH; Lynn S; Geng FS; Cui L; Yan S; Achinger-Kawecka J; Stirzaker C; Norris MD; Haber M; Trahair TN; Speleman F; De Preter K; Cowley MJ; Bogdanovic O; Timpson P; Cox TR; Kolch W; Fletcher JI; Fey D; Croucher DR, 2023, 'Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.abp8314

Weerakoon AT; Condon N; Cox TR; Sexton C; Cooper C; Meyers IA; Thomson D; Ford PJ; Roy S; Symons AL, 2022, 'Dynamic dentin: A quantitative microscopic assessment of age and spatial changes to matrix architecture, peritubular dentin, and collagens types I and III', Journal of Structural Biology, 214, http://dx.doi.org/10.1016/j.jsb.2022.107899

Parker AL; Bowman E; Zingone A; Ryan BM; Cooper WA; Kohonen-Corish M; Harris CC; Cox TR, 2022, 'Extracellular matrix profiles determine risk and prognosis of the squamous cell carcinoma subtype of non-small cell lung carcinoma', Genome Medicine, 14, http://dx.doi.org/10.1186/s13073-022-01127-6

Papanicolaou M; Parker AL; Yam M; Filipe EC; Wu SZ; Chitty JL; Wyllie K; Tran E; Mok E; Nadalini A; Skhinas JN; Lucas MC; Herrmann D; Nobis M; Pereira BA; Law AMK; Castillo L; Murphy KJ; Zaratzian A; Hastings JF; Croucher DR; Lim E; Oliver BG; Mora FV; Parker BL; Gallego-Ortega D; Swarbrick A; O’Toole S; Timpson P; Cox TR, 2022, 'Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-32255-7

Jamaluddin MFB; Ghosh A; Ingle A; Mohammed R; Ali A; Bahrami M; Kaiko G; Gibb Z; Filipe EC; Cox TR; Boulton A; O’Sullivan R; Ius Y; Karakoti A; Vinu A; Nahar P; Jaaback K; Bansal V; Tanwar PS, 2022, 'Bovine and human endometrium-derived hydrogels support organoid culture from healthy and cancerous tissues', Proceedings of the National Academy of Sciences of the United States of America, 119, http://dx.doi.org/10.1073/pnas.2208040119

Law AMK; Chen J; Colino-Sanguino Y; Fuente LRDL; Fang G; Grimes SM; Lu H; Huang RJ; Boyle ST; Venhuizen J; Castillo L; Tavakoli J; Skhinas JN; Millar EKA; Beretov J; Rossello FJ; Tipper JL; Ormandy CJ; Samuel MS; Cox TR; Martelotto L; Jin D; Valdes-Mora F; Ji HP; Gallego-Ortega D, 2022, 'ALTEN: A High-Fidelity Primary Tissue-Engineering Platform to Assess Cellular Responses Ex Vivo', Advanced Science, 9, http://dx.doi.org/10.1002/advs.202103332

Rad MA; Mahmodi H; Filipe EC; Cox TR; Kabakova I; Tipper JL, 2022, 'Micromechanical characterisation of 3D bioprinted neural cell models using Brillouin microspectroscopy', Bioprinting, 25, http://dx.doi.org/10.1016/j.bprint.2021.e00179

Dreyer SB; Upstill-Goddard R; Legrini A; Biankin AV; Allison S; Beraldi D; Cameron E; Chang DK; Cooke SL; Cunningham R; Grimwood P; Kelly S; Marshall J; McDade B; Musgrove EA; Ramsay D; Evers L; Rebus S; Rahib L; Serrels B; Jamieson NB; McKay CJ; Westwood P; Williams N; Duthie F; Shen W; Pea A; Johns AL; Gill AJ; Chantrill LA; Timpson P; Chou A; Pajic M; Dwarte T; Herrmann D; Vennin C; Cox TR; Pereira B; Ritchiee S; Reed DA; Chambers CR; Metcalf X; Nobis M; Jeong G; Kenyon L; Lyons RJ; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; McLeod D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O'Rourke TJ; Fawcett JW, 2022, 'Genomic and Molecular Analyses Identify Molecular Subtypes of Pancreatic Cancer Recurrence', Gastroenterology, 162, pp. 320 - 324.e4, http://dx.doi.org/10.1053/j.gastro.2021.09.022

Guo G; Papanicolaou M; Demarais NJ; Wang Z; Schey KL; Timpson P; Cox TR; Grey AC, 2021, 'Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-23461-w

Lakis V; Lawlor RT; Newell F; Patch AM; Mafficini A; Sadanandam A; Koufariotis LT; Johnston RL; Leonard C; Wood S; Rusev B; Corbo V; Luchini C; Cingarlini S; Landoni L; Salvia R; Milella M; Chang D; Bailey P; Jamieson NB; Duthie F; Gingras MC; Muzny DM; Wheeler DA; Gibbs RA; Milione M; Chantrill LA; Timpson P; Chou A; Pajic M; Murphy A; Dwarte T; Hermann D; Vennin C; Cox TR; Pereira B; Ritchie S; Reed DA; Chambers CR; Metcalf X; Nobis M; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Xu Q; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Pavey D; Das A; Cosman PH; Ismail K; O’Connnor C; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forest C; Ballal M; Fletcher DR; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Dixon J; Scardoni M; Bassi C; Grimaldi S; Cantù C; Bonizzato G; Bersani S; Biankin A; Johns A; Herrmann D, 2021, 'DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association', Communications Biology, 4, pp. 155, http://dx.doi.org/10.1038/s42003-020-01469-0

Liu D; Sharbeen G; Phillips P; Johns AL; Gill AJ; Chantrill LA; Timpson P; Chou A; Pajic M; Dwarte T; Herrmann D; Vennin C; Cox TR; Pereira B; Ritchie S; Reed DA; Chambers CR; Metcalf X; Nobis M; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Scarpa A; Lawlor RT; Corbo V; Bassi C; Biankin AV; Jamieson NB; Chang DK; Dreyer SB; Ford CE, 2021, 'ROR1 and ROR2 expression in pancreatic cancer', BMC Cancer, 21, http://dx.doi.org/10.1186/s12885-021-08952-9

Murphy KJ; Reed DA; Vennin C; Conway JRW; Nobis M; Yin JX; Chambers CR; Pereira BA; Lee V; Filipe EC; Trpceski M; Ritchie S; Lucas MC; Warren SC; Skhinas JN; Magenau A; Metcalf XL; Stoehr J; Major G; Parkin A; Bidanel R; Lyons RJ; Zaratzian A; Tayao M; Da Silva A; Abdulkhalek L; Gill AJ; Johns AL; Biankin AV; Samra J; Grimmond SM; Chou A; Goetz JG; Samuel MS; Lyons JG; Burgess A; Caldon CE; Horvath LG; Daly RJ; Gadegaard N; Wang Y; Sansom OJ; Morton JP; Cox TR; Pajic M; Herrmann D; Timpson P, 2021, 'Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status', Science Advances, 7, http://dx.doi.org/10.1126/sciadv.abh0363

Es HA; Cox TR; Sarafraz-Yazdi E; Thiery JP; Warkiani ME, 2021, 'Pirfenidone reduces epithelial–mesenchymal transition and spheroid formation in breast carcinoma through targeting cancer-associated fibroblasts (Cafs)', Cancers, 13, http://dx.doi.org/10.3390/cancers13205118

Polonchuk L; Surija L; Lee MH; Sharma P; Ming CLC; Richter F; Ben-Sefer E; Rad MA; Sarmast HMS; Al Shamery W; Tran HA; Vettori L; Haeusermann F; Filipe EC; Rnjak-Kovacina J; Cox T; Tipper J; Kabakova I; Gentile C, 2021, 'Towards engineering heart tissues from bioprinted cardiac spheroids', Biofabrication, 13, http://dx.doi.org/10.1088/1758-5090/ac14ca

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496

Valdés-Mora F; Salomon R; Gloss BS; Law AMK; Venhuizen J; Castillo L; Murphy KJ; Magenau A; Papanicolaou M; Rodriguez de la Fuente L; Roden DL; Colino-Sanguino Y; Kikhtyak Z; Farbehi N; Conway JRW; Sikta N; Oakes SR; Cox TR; O'Donoghue SI; Timpson P; Ormandy CJ; Gallego-Ortega D, 2021, 'Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype', Cell Reports, 35, http://dx.doi.org/10.1016/j.celrep.2021.108945

Cox TR, 2021, 'The matrix in cancer', Nature Reviews Cancer, 21, pp. 217 - 238, http://dx.doi.org/10.1038/s41568-020-00329-7

Holliday H; Roden D; Junankar S; Wu SZ; Baker LA; Krisp C; Chan CL; McFarland A; Skhinas JN; Cox TR; Pal B; Huntington ND; Ormandy CJ; Carroll JS; Visvader J; Molloy MP; Swarbrick A, 2021, 'Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB', iScience, 24, http://dx.doi.org/10.1016/j.isci.2021.102072

Setargew YFI; Wyllie K; Grant RD; Chitty JL; Cox TR, 2021, 'Targeting lysyl oxidase family meditated matrix cross‐linking as an anti‐stromal therapy in solid tumours', Cancers, 13, pp. 1 - 26, http://dx.doi.org/10.3390/cancers13030491

Michael P; Lam YT; Filipe EC; Tan RP; Chan AHP; Lee BSL; Feng N; Hung J; Cox TR; Santos M; Wise SG, 2020, 'Plasma polymerized nanoparticles effectively deliver dual siRNA and drug therapy in vivo', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-69591-x

Wu SZ; Roden DL; Wang C; Holliday H; Harvey K; Cazet AS; Murphy KJ; Pereira B; Al-Eryani G; Bartonicek N; Hou R; Torpy JR; Junankar S; Chan CL; Lam CE; Hui MN; Gluch L; Beith J; Parker A; Robbins E; Segara D; Mak C; Cooper C; Warrier S; Forrest A; Powell J; O'Toole S; Cox TR; Timpson P; Lim E; Liu XS; Swarbrick A, 2020, 'Stromal cell diversity associated with immune evasion in human triple-negative breast cancer', EMBO Journal, 39, pp. e104063, http://dx.doi.org/10.15252/embj.2019104063

Parker AL; Cox TR, 2020, 'The Role of the ECM in Lung Cancer Dormancy and Outgrowth', Frontiers in Oncology, 10, http://dx.doi.org/10.3389/fonc.2020.01766

Nobis M; Herrmann D; Warren SC; Strathdee D; Cox TR; Anderson KI; Timpson P, 2020, 'Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse', Small GTPases, 11, pp. 240 - 247, http://dx.doi.org/10.1080/21541248.2018.1438024

Wu S; Roden D; Wang C; Holliday H; Harvey K; Cazet A; Murphy K; Pereira B; Al-Eryani G; Bartonicek N; Hou R; Torpy J; Junankar S; Chan C-L; Lam E; Hui M; Gluch L; Beith J; Parker A; Robbins E; Segara D; Mak C; Cooper C; Warrier S; Forrest A; Powell J; O’Toole S; Cox T; Timpson P; Lim E; Liu S; Swarbrick A, 2020, 'Single-cell analysis reveals diverse stromal subsets associated with immune evasion in triple-negative breast cancer', bioRxiv, http://dx.doi.org/10.1101/2020.06.04.135327

Chitty JL; Skhinas JN; Filipe EC; Wang S; Cupello CR; Grant RD; Yam M; Papanicolaou M; Major G; Zaratzian A; Da Silva AM; Tayao M; Vennin C; Timpson P; Madsen CD; Cox TR, 2020, 'The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development', Cancer Reports, 3, http://dx.doi.org/10.1002/cnr2.1209

Elgundi Z; Papanicolaou M; Major G; Cox TR; Melrose J; Whitelock JM; Farrugia BL, 2020, 'Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan', Frontiers in Oncology, 9, pp. 1482, http://dx.doi.org/10.3389/fonc.2019.01482

Vennin C; Mélénec P; Rouet R; Nobis M; Cazet AS; Murphy KJ; Herrmann D; Reed DA; Lucas MC; Warren SC; Elgundi Z; Pinese M; Kalna G; Roden D; Samuel M; Zaratzian A; Grey ST; Da Silva A; Leung W; Johns AL; Chantrill LA; Chou A; Steinmann A; Arshi M; Dwarte T; Froio D; Pereira B; Ritchie S; Chambers CR; Metcalf X; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Christ A; Bruxner T; Samra JS; Pavlakis N; High HA; Asghari R; Merrett ND; Pavey D; Das A; Cosman PH; Ismail K; O’Connnor C; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Cooper CL; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forest C; Epari KP; Ballal M; Fletcher DR; Mukhedkar S; Zeps N; Beilin M; Feeney K; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Lawlor RT; Beghelli S; Corbo V; Scardoni M; Bassi C; Christ D; Cox T; Timpson P; Phillips P; Whitelock J; Pajic M; Gill A; Croucher D, 2019, 'CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan', Nature Communications, 10, pp. 3637, http://dx.doi.org/10.1038/s41467-019-10968-6

Chitty JL; Setargew YFI; Cox TR, 2019, 'Targeting the lysyl oxidases in tumour desmoplasia', Biochemical Society Transactions, 47, pp. 1661 - 1678, http://dx.doi.org/10.1042/BST20190098

Pereira BA; Vennin C; Papanicolaou M; Chambers CR; Herrmann D; Morton JP; Cox TR; Timpson P, 2019, 'CAF Subpopulations: A New Reservoir of Stromal Targets in Pancreatic Cancer', Trends in Cancer, 5, pp. 724 - 741, http://dx.doi.org/10.1016/j.trecan.2019.09.010

Zijlstra A; Von Lersner A; Yu D; Borrello L; Oudin M; Kang Y; Sahai E; Fingleton B; Stein U; Cox TR; Price JT; Kato Y; Welm AL; Aguirre-Ghiso JA, 2019, 'The importance of developing therapies targeting the biological spectrum of metastatic disease', Clinical and Experimental Metastasis, 36, pp. 305 - 309, http://dx.doi.org/10.1007/s10585-019-09972-3

Zeltz C; Pasko E; Cox TR; Navab R; Tsao MS, 2019, 'LOXL1 is regulated by integrin α11 and promotes non-small cell lung cancer tumorigenicity', Cancers, 11, http://dx.doi.org/10.3390/cancers11050705

Beadnell T; Borriello L; Christenson J; Fornetti J; Guldner I; Hanna A; Kyjacova L; Marinak-Whately K; de Melo Martins PC; Rotinen M; te Boekhorst V; Cox TR, 2019, 'Meeting report: Metastasis Research Society (MRS) 17th Biennial conference and associated Young Investigator Satellite Meeting (YISM) on cancer metastasis', Clinical and Experimental Metastasis, 36, pp. 119 - 137, http://dx.doi.org/10.1007/s10585-018-09953-y

Kennedy SP; Han JZR; Portman N; Nobis M; Hastings JF; Murphy KJ; Latham SL; Cadell AL; Miladinovic D; Marriott GR; O'Donnell YEI; Shearer RF; Williams JT; Munoz AG; Cox TR; Watkins DN; Saunders DN; Timpson P; Lim E; Kolch W; Croucher DR, 2019, 'Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer', Breast Cancer Research, 21, http://dx.doi.org/10.1186/s13058-019-1127-y

Nguyen EV; Pereira BA; Lawrence MG; Ma X; Rebello RJ; Chan H; Niranjan B; Wu Y; Ellem S; Guan X; Wu J; Skhinas JN; Cox TR; Risbridger GP; Taylor RA; Lister NL; Daly RJ, 2019, 'Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment', Molecular and Cellular Proteomics, 18, pp. 1410 - 1427, http://dx.doi.org/10.1074/mcp.RA119.001496


Back to profile page