Select Publications

Journal articles

Phan K; He Y; Pickford R; Bhatia S; Katzeff JS; Hodges JR; Piguet O; Halliday GM; Kim WS, 2020, 'Uncovering pathophysiological changes in frontotemporal dementia using serum lipids', Scientific Reports, vol. 10,

Liew G; Tse B; Ho IV; Joachim N; White A; Pickford R; Maltby D; Gopinath B; Mitchell P; Crossett B, 2020, 'Acylcarnitine abnormalities implicate mitochondrial dysfunction in patients with neovascular age-related macular degeneration', Investigative Ophthalmology and Visual Science, vol. 61,

Wong MWK; Thalamuthu A; Braidy N; Mather KA; Liu Y; Ciobanu L; Baune BT; Armstrong NJ; Kwok J; Schofield P; Wright MJ; Ames D; Pickford R; Lee T; Poljak A; Sachdev PS, 2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older australian twins', eLife, vol. 9, pp. 1 - 28,

Shimabukuro Okuda L; Tallada Iborra R; Ramos Pinto P; Fabres Machado U; Corrêa-Giannella ML; Pickford R; Woods T; Brimble MA; Rye KA; Passarelli M, 2020, 'Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages', Mediators of Inflammation, vol. 2020,

Liu Y; Chan DKY; Thalamuthu A; Wen W; Jiang J; Paradise M; Lee T; Crawford J; Wai Kin Wong M; Hua Xu Y; Poljak A; Pickford R; Sachdev PS; Braidy N, 2020, 'Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia', Computational and Structural Biotechnology Journal, vol. 18, pp. 1613 - 1624,

Stayte S; Laloli KJ; Rentsch P; Lowth A; Li KM; Pickford R; Vissel B, 2020, 'The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain', Experimental Neurology, vol. 323,

Coffey MJ; Nielsen S; Wemheuer B; Kaakoush NO; Garg M; Needham B; Pickford R; Jaffe A; Thomas T; Ooi CY, 2019, 'Gut Microbiota in Children With Cystic Fibrosis: A Taxonomic and Functional Dysbiosis', Scientific Reports, vol. 9, pp. 18593,

Tetu SG; Sarker I; Schrameyer V; Pickford R; Elbourne LDH; Moore LR; Paulsen IT, 2019, 'Plastic leachates impair growth and oxygen production in Prochlorococcus, the ocean’s most abundant photosynthetic bacteria', Communications Biology, vol. 2,

Wong MWK; Braidy N; Pickford R; Sachdev PS; Poljak A, 2019, 'Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma', Frontiers in Neurology, vol. 10, pp. 1 - 11,

Wong MWK; Braidy N; Pickford R; Vafaee F; Crawford J; Muenchhoff J; Schofield P; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI', PLoS ONE, vol. 14, pp. e0214141,

D'Agostino PM; Woodhouse JN; Liew HT; Sehnal L; Pickford R; Wong HL; Burns BP; Neilan BA, 2019, 'Bioinformatic, phylogenetic and chemical analysis of the UV-absorbing compounds scytonemin and mycosporine-like amino acids from the microbial mat communities of Shark Bay, Australia', Environmental Microbiology, vol. 21, pp. 702 - 715,

Wong MWK; Braidy N; Crawford J; Pickford R; Song F; Mather KA; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health', Journal of Alzheimer's Disease, vol. 72, pp. 703 - 716,

Atashrazm F; Hammond D; Perera G; Dobson-Stone C; Mueller N; Pickford R; Kim WS; Kwok JB; Lewis SJG; Halliday GM; Dzamko N, 2018, 'Reduced glucocerebrosidase activity in monocytes from patients with Parkinson’s disease', Scientific Reports, vol. 8,

Giardina M; Cheong S; Marjo CE; Clode PL; Guagliardo P; Pickford R; Pernice M; Seymour JR; Raina JB, 2018, 'Quantifying inorganic nitrogen assimilation by synechococcus using bulk and single-cell mass spectrometry: A comparative study', Frontiers in Microbiology, vol. 9, pp. 2847,

Cullen A; D'Agostino PM; Mazmouz R; Pickford R; Wood S; Neilan BA, 2018, 'Insertions within the Saxitoxin Biosynthetic Gene Cluster Result in Differential Toxin Profiles', ACS Chemical Biology, vol. 13, pp. 3107 - 3114,

Aw WC; Towarnicki SG; Melvin RG; Youngson NA; Garvin MR; Hu Y; Nielsen S; Thomas T; Pickford R; Bustamante S; Vila-Sanjurjo A; Smyth GK; Ballard JWO, 2018, 'Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness', PLoS Genetics, vol. 14, pp. e1007735,

Unnikrishnan A; Vo ANQ; Pickford R; Raftery MJ; Nunez AC; Verma A; Hesson LB; Pimanda JE, 2018, 'AZA-MS: A novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo', Leukemia, vol. 32, pp. 900 - 910,

Kim WS; Jary E; Pickford R; He Y; Ahmed RM; Piguet O; Hodges JR; Halliday GM, 2018, 'Lipidomics analysis of behavioral variant frontotemporal dementia: A scope for biomarker development', Frontiers in Neurology, vol. 9,

Iborra RT; Machado-Lima A; Okuda LS; Pinto PR; Nakandakare ER; Machado UF; Correa-Giannella ML; Pickford R; Woods T; Brimble MA; Rye KA; Lu R; Yokoyama S; Passarelli M, 2018, 'AGE-albumin enhances ABCA1 degradation by ubiquitin-proteasome and lysosomal pathways in macrophages', Journal of Diabetes and its Complications, vol. 32, pp. 1 - 10,

von Jonquieres G; Spencer ZHT; Rowlands BD; Klugmann CB; Bongers A; Harasta AE; Parley KE; Cederholm J; Teahan O; Pickford R; Delerue F; Ittner LM; Fröhlich D; McLean CA; Don AS; Schneider M; Housley GD; Rae CD; Klugmann M, 2018, 'Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy', Acta Neuropathologica, vol. 135, pp. 95 - 113,

Vishnumohan S; Pickford R; Arcot J, 2017, 'Naturally occurring folates in selected traditionally prepared foods in Southern India', Journal of Food Science and Technology, vol. 54, pp. 4173 - 4180,

Pereyra JPA; D'Agostino PM; Mazmouz R; Woodhouse JN; Pickford R; Jameson I; Neilan BA, 2017, 'Molecular and morphological survey of saxitoxin-producing cyanobacterium Dolichospermum circinale (Anabaena circinalis) isolated from geographically distinct regions of Australia', Toxicon, vol. 138, pp. 68 - 77,

da Silva KS; Pinto PR; Fabre NT; Gomes DJ; Thieme K; Okuda LS; Iborra RT; Freitas VG; Shimizu MHM; Teodoro WR; Marie SKN; Woods T; Brimble MA; Pickford R; Rye KA; Okamoto M; Catanozi S; Correa-Giannela ML; Machado UF; Passarelli M, 2017, 'N-acetylcysteine counteracts adipose tissue macrophage infiltration and insulin resistance elicited by advanced glycated albumin in healthy rats', Frontiers in Physiology, vol. 8,

Liu T; Mazmouz R; Ongley SE; Chau R; Pickford R; Woodhouse JN; Neilan BA, 2017, 'Directing the Heterologous Production of Specific Cyanobacterial Toxin Variants', ACS Chemical Biology, vol. 12, pp. 2021 - 2029,

Wong MW; Braidy N; Poljak A; Pickford R; Thambisetty M; Sachdev PS, 2017, 'Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers', Alzheimers Dement, vol. 13, pp. 810 - 827,

Gomes DJ; Velosa AP; Okuda LS; Fusco FB; da Silva KS; Pinto PR; Nakandakare ER; Correa-Giannella ML; Woods T; Brimble MA; Pickford R; Rye KA; Teodoro WR; Catanozi S; Passarelli M, 2016, 'Glycated albumin induces lipid infiltration in mice aorta independently of DM and RAS local modulation by inducing lipid peroxidation and inflammation', Journal of Diabetes and its Complications, vol. 30, pp. 1614 - 1621,

Kaakoush NO; Pickford R; Jaffe A; Ooi CY, 2016, 'Is there a role for stool metabolomics in cystic fibrosis?', Pediatrics International, vol. 58, pp. 808 - 811,

Richards SL; Cawley AT; Cavicchioli R; Suann CJ; Pickford R; Raftery MJ, 2016, 'Aptamer based peptide enrichment for quantitative analysis of gonadotropin-releasing hormone by LC-MS/MS', Talanta, vol. 150, pp. 671 - 680,

Hart-Smith G; Yagoub D; Tay AP; Pickford R; Wilkins MR, 2016, 'Large scale mass spectrometry-based identifications of enzyme-mediated protein methylation are subject to high false discovery rates', Molecular and Cellular Proteomics, vol. 15, pp. 989 - 1006,

Kashem MA; Ahmed S; Sultana N; Ahmed EU; Pickford R; Rae C; Šerý O; McGregor IS; Balcar VJ, 2016, 'Metabolomics of neurotransmitters and related metabolites in post-mortem tissue from the dorsal and ventral striatum of alcoholic human brain', Neurochemical Research, vol. 41, pp. 385 - 397,

D'Agostino PM; Javalkote VS; Mazmouz R; Pickford R; Puranik PR; Neilan BA, 2016, 'Comparative profiling and discovery of novel glycosylated mycosporine-like amino acids in two strains of the cyanobacterium Scytonema cf. crispum', Applied and Environmental Microbiology, vol. 82, pp. 5951 - 5959,

Katoch M; Mazmouz R; Chau R; Pearson LA; Pickford R; Neilan BA, 2016, 'Heterologous production of cyanobacterial mycosporine-like amino acids mycosporine-ornithine and mycosporine-lysine in Escherichia coli', Applied and Environmental Microbiology, vol. 82, pp. 6167 - 6173,

Toscan CE; Rahimi M; Bhadbhade M; Pickford R; McAlpine SR; Lock RB, 2015, 'Thioimidazoline based compounds reverse glucocorticoid resistance in human acute lymphoblastic leukemia xenografts', Organic and Biomolecular Chemistry, vol. 13, pp. 6299 - 6312,

Couttas TA; Kain N; Daniels B; Lim XY; Shepherd C; Kril J; Pickford R; Li H; Garner B; Don AS, 2014, 'Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis', Acta Neuropathologica Communications, vol. 2,

Yau YY; Leong RWL; Shin S; Bustamante S; Pickford R; Hejazi L; Campbell B; Wasinger VC, 2014, 'Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases', Discovery Medicine, vol. 18, pp. 113 - 124

Liu J; Pickford R; Meagher AP; Ward RL, 2011, 'Quantitative analysis of tissue folate using ultra-high performance liquid chromatography tandem mass spectrometry', Analytical Biochemistry, vol. 411, pp. 210 - 217,

Bustamante S; Pickford R; Shin S; Luber R; Campbell B; Redmond D; Yau Y; Leong RWL; Wasinger V, 2010, 'Metabolomics in inflammatory bowel disease', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 25, pp. A83 - A83,

dos Remedios CG; Estigoy C; Cameron D; Ho JWK; Herbert B; Padula M; Pickford R; Guilhaus M; Odeberg J; Ponten F, 2010, 'Proteomics of the Human Cardiac Intercalated Disc: A More Complex Multi-Functional Structure than was Previously Thought', Biophysical Journal, vol. 98, pp. 755a - 756a,

Kellmann R; Mihali TK; Jae jeon Y; Pickford R; Pomati F; Neilan BA, 2008, 'Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteria', Applied and Environmental Microbiology, vol. 74, pp. 4044 - 4053,

Gruendling T; Pickford R; Guilhaus M; Barner-Kowollik CW, 2008, 'Degradation of RAFT Polymers in a Cyclic Ether Studied via High Resolution ESI-MS: Implications for Synthesis, Storage, and End-Group Modification', Journal of Polymer Science Part A - Polymer Chemistry, vol. 46, pp. 7447 - 7461,

Rodrigues JA; Taylor AM; Sumpton DP; Reynolds JC; Pickford R; Thomas-Oates J, 2007, 'Mass Spectrometry of Carbohydrates: Newer Aspects', Advances in Carbohydrate Chemistry and Biochemistry, vol. 61, pp. 59 - 141,

Fedorow HS; Pickford R; Kettle E; Cartwright M; Halliday GM; Gerlach M; Riederer P; Garner B; Double KL, 2006, 'Investigation of the lipid component of neuromelanin', Journal of Neural Transmission, vol. 113, pp. 735 - 739,

Fedorow HS; Pickford R; Hook JM; Double KL; Halliday GM; Gerlach M; Riederer P; Garner B, 2005, 'Dolichol is the major lipid component of human substantia nigra neuromelanin', Journal of Neurochemistry, vol. 92, pp. 990 - 995,

White IR; Pickford R; Wood J; Skehel JM; Gangadharan B; Cutler P, 2004, 'A statistical comparison of silver and SYPRO Ruby staining for proteomic analysis', Electrophoresis, vol. 25, pp. 3048 - 3054,

Hansen HR; Pickford R; Thomas-Oates J; Jaspars M; Feldmann J, 2004, '2-Dimethylarsinothioyl Acetic Acid Identified in a Biological Sample: The First Occurrence of a Mammalian Arsinothioyl Metabolite', Angewandte Chemie - International Edition, vol. 43, pp. 337 - 340,

Kuiper I; Lagendijk EL; Pickford R; Derrick JP; Lamers GEM; Thomas-Oates JE; Lugtenberg BJJ; Bloemberg GV, 2004, 'Characterization of two Pseudomonas putida lipopeptide biosurfactants, putisolvin I and II, which inhibit biofilm formation and break down existing biofilms', Molecular Microbiology, vol. 51, pp. 97 - 113,

Miguens-Rodriguez M; Pickford R; Thomas-Oates JE; Pergantis SA, 2002, 'Arsenosugar identification in seaweed extracts using high-performance liquid chromatography/electrospray ion trap mass spectrometry', Rapid Communications in Mass Spectrometry, vol. 16, pp. 323 - 331,

Pickford R; Miguens-Rodriguez M; Afzaal S; Speir P; Pergantis SA; Thomas-Oates JE, 2002, 'Application of the high mass accuracy capabilities of FT-ICR-MS and Q-ToF-MS to the characterisation of arsenic compounds in complex biological matrices', Journal of Analytical Atomic Spectrometry, vol. 17, pp. 173 - 176,

Cutler P; Bell DJ; Birrell HC; Connelly JC; Connor SC; Holmes E; Mitchell BC; Monté SY; Neville BA; Pickford R; Polley S; Schneider K; Skehel JM, 1999, 'An integrated proteomic approach to studying glomerular nephrotoxicity', Electrophoresis, vol. 20, pp. 3647 - 3658,<3647::aid-elps3647>;2-%23

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