By Professor Andrew John Brown

Journal articles

Brown AJ; Dean RT; Jessup W, 2000, 'Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture', Atherosclerosis, 151, pp. 291 - 291, http://dx.doi.org/10.1016/s0021-9150(00)81322-2

Lyons MA; Samman S; Gatto L; Brown AJ, 1999, 'Rapid hepatic metabolism of 7-ketocholesterol in vivo: Implications for dietary oxysterols', Journal of Lipid Research, 40, pp. 1846 - 1857

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1999, 'Oxysterol efflux from macrophage foam cells: The essential role of acceptor phospholipid', Journal of Lipid Research, 40, pp. 1636 - 1646

Brown AJ; Cartland S; Kraemer FB; Dean RT; Jessup W, 1999, 'Oxysterol-regulation of cholesterol esterification and hydrolysis in macrophages', FASEB JOURNAL, 13, pp. A1378 - A1378, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082033400334&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lyons MA; Samman S; Gatto L; Brown AJ, 1999, 'Rapid hepatic metabolism of 7-Ketocholesterol in vivo: Implications for dietary oxysterols', FASEB JOURNAL, 13, pp. A1378 - A1378, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082033400332&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lyons MA; Brown AJ, 1999, '7-Ketocholesterol', International Journal of Biochemistry and Cell Biology, 31, pp. 369 - 375, http://dx.doi.org/10.1016/S1357-2725(98)00123-X

Brown AJ; Jessup W, 1999, 'Oxysterols and atherosclerosis', Atherosclerosis, 142, pp. 1 - 28, http://dx.doi.org/10.1016/S0021-9150(98)00196-8

Alwan CL; Brown AJ; Cooper VA; Samman S, 1999, 'The role of ascorbic acid in the mosaic of coronary heart disease: Lipid metabolism and antioxidant functions', Journal of Clinical Biochemistry and Nutrition, 26, pp. 85 - 98, http://dx.doi.org/10.3164/jcbn.26.85

Brown AJ, 1999, 'What's sex got to do with it?', Current opinion in lipidology, 10, pp. 641 - 644, http://dx.doi.org/10.1097/00041433-199912000-00022

Brown AJ, 1998, 'Paradoxical effects of acute cigarette smoking on plasma antioxidant status in humans', Nutrition Research, 18, pp. 1499 - 1519, http://dx.doi.org/10.1016/S0271-5317(98)00126-2

Gelissen IC; Hochgrebe T; Wilson MR; Easterbrook-Smith SB; Jessup W; Dean RT; Brown AJ, 1998, 'Apolipoprotein J (clusterin) induces cholesterol export from macrophage-foam cells: A potential anti-atherogenic function?', Biochemical Journal, 331, pp. 231 - 237, http://dx.doi.org/10.1042/bj3310231

Fragoso YD; Brown AJ, 1998, 'In vivo metabolism of alpha-tocopherol in lipoproteins and liver: studies on rabbits in response to acute cholesterol loading.', São Paulo medical journal = Revista paulista de medicina, 116, pp. 1753 - 1759, http://dx.doi.org/10.1590/S1516-31801998000400003

Lyons MA; Samman S; Brown AJ, 1997, '7-Ketocholesterol and cholesterol incorporated into modified lipoprotein have very different kinetics when injected into rats', ATHEROSCLEROSIS, 134, pp. 30 - 30, http://dx.doi.org/10.1016/S0021-9150(97)88247-0

Gelissen IC; Hochgrebe T; Wilson MR; EasterbrookSmith SB; Jessup W; Dean RT; Brown AJ, 1997, 'Apolipoprotein J (clusterin) induces cholesterol export from macrophage foam cells: A potential anti-atherogenic function?', ATHEROSCLEROSIS, 134, pp. 367 - 367, http://dx.doi.org/10.1016/S0021-9150(97)89866-8

Jessup W; Mander EL; Brown AJ; Gelissen IC; Kritharides L; Dean RT, 1997, 'Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells', ATHEROSCLEROSIS, 134, pp. 231 - 232, http://dx.doi.org/10.1016/S0021-9150(97)89233-7

Brown AJ; Dean RT; Jessup W, 1997, 'Free and esterified oxysterols in human atherosclerotic plaque', ATHEROSCLEROSIS, 134, pp. 210 - 210, http://dx.doi.org/10.1016/S0021-9150(97)89083-1

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1997, 'Phospholipid association with apo A-I stimulates oxysterol efflux from macrophage foam cells', ATHEROSCLEROSIS, 134, pp. 367 - 367, http://dx.doi.org/10.1016/S0021-9150(97)89866-8

Brown AJ; Leong SL; Dean RT; Jessup W, 1997, '7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque', Journal of Lipid Research, 38, pp. 1730 - 1745

Samman S; Brown AJ; Beltran C; Singh S, 1997, 'The effect of ascorbic acid on plasma lipids and oxidisability of LDL in male smokers', European Journal of Clinical Nutrition, 51, pp. 472 - 477, http://dx.doi.org/10.1038/sj.ejcn.1600431

Kritharides L; Kus M; Brown AJ; Jessup W; Dean RT, 1996, 'Hydroxypropyl-β-cyclodextrin-mediated efflux of 7-ketocholesterol from macrophage foam cells', Journal of Biological Chemistry, 271, pp. 27450 - 27455, http://dx.doi.org/10.1074/jbc.271.44.27450

Gelissen IG; Brown AJ; Mander EL; Kritharides L; Dean RT; Jessup W, 1996, 'Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol', Journal of Biological Chemistry, 271, pp. 17852 - 17860, http://dx.doi.org/10.1074/jbc.271.30.17852

Gatto LM; Hallen GK; Brown AJ; Samman S, 1996, 'Ascorbic acid induces a favorable lipoprotein profile in women.', Journal of the American College of Nutrition, 15, pp. 154 - 158, http://dx.doi.org/10.1080/07315724.1996.10718581

Brown AJ; Dean RT; Jessup W, 1996, 'Free and esterified oxysterol: Formation during copper-oxidation of low density lipoprotein and uptake by macrophages', Journal of Lipid Research, 37, pp. 320 - 335

Brown AJ, 1996, 'Acute effects of smoking cessation on antioxidant status', Journal of Nutritional Biochemistry, 7, pp. 29 - 39, http://dx.doi.org/10.1016/0955-2863(95)00164-6

Brown AJ, 1996, 'Atherosclerosis: cell biology and lipoproteins.', Current opinion in lipidology, 7, http://dx.doi.org/10.1097/00041433-199610000-00019

Brown AJ, 1995, 'Atherosclerosis: cell biology and lipoproteins.', Current opinion in lipidology, 6, http://dx.doi.org/10.1097/00041433-199504000-00015

van Reyk DM; Brown AJ; Jessup W; Dean RT, 1995, 'Batch-to-batch variation of chelex-100 confounds metal-catalysed oxidation. Leaching of inhibitory compounds from a batch of chelex-100 and their removal by a pre-washing procedure', Free Radical Research, 23, pp. 533 - 535, http://dx.doi.org/10.3109/10715769509065274

Brown AJ; Fragoso YD, 1994, 'Tocopherols and carotenes are differently distributed in subfractions of high-density lipoprotein', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, 1210, pp. 373 - 376, http://dx.doi.org/10.1016/0005-2760(94)90243-7

Riemersma RA; Perkins D; Brown AJ; Brown J, 1994, 'Linoleic acid and coronary artery disease.', The American journal of clinical nutrition, 59, pp. 949 - 950, http://dx.doi.org/10.1093/ajcn/59.4.949

Riemersma RA; Perkins D; Brown AJ; Brown J, 1994, 'Linoleic acid and coronary artery disease', The American Journal of Clinical Nutrition, 59, pp. 949 - 949, http://dx.doi.org/10.1093/ajcn/59.4.949

Brown AJ, 1992, 'Atherosclerosis: Cell biology and lipoproteins', Current Opinion in Lipidology, 3, http://dx.doi.org/10.1097/00041433-199204000-00018

Brown AJ; Roberts DCK, 1991, 'Fish and fish oil intake: Effect on haematological variables related to cardiovascular disease', Thrombosis Research, 64, pp. 169 - 178, http://dx.doi.org/10.1016/0049-3848(91)90116-E

Brown AJ; Pang E; Roberts DCK, 1991, 'Erythrocyte eicosapentaenoic acid versus docosahexaenoic acid as a marker for fish and fish oil consumption', Prostaglandins, Leukotrienes and Essential Fatty Acids, 44, pp. 103 - 106, http://dx.doi.org/10.1016/0952-3278(91)90191-7

Brown AJ; Roberts DCK, 1991, 'Moderate fish oil intake improves lipemic response to a standard fat meal: A study in 25 healthy men', Arteriosclerosis, Thrombosis, and Vascular Biology, 11, pp. 457 - 466

Brown AJ; Pang E; Roberts DCK, 1991, 'Persistent changes in the fatty acid composition of erythrocyte membranes after moderate intake of n-3 polyunsaturated fatty acids: Study design implications', American Journal of Clinical Nutrition, 54, pp. 668 - 673

Brown AJ; Roberts DCK, 1991, 'The effect of fasting triacylglyceride concentration and apolipoprotein E polymorphism on postprandial lipemia', Arteriosclerosis, Thrombosis, and Vascular Biology, 11, pp. 1737 - 1744

Brown AJ; Roberts DCK, 1990, 'Erythrocyte EPA as a marker for intake of fish and fish oil', European Journal of Clinical Nutrition, 44, pp. 487 - 488

Brown AJ; Roberts DCK; Pritchard JE; Truswell AS, 1990, 'A mixed Australian fish diet and fish-oil supplementation: Impact on the plasma lipid profile of healthy men', American Journal of Clinical Nutrition, 52, pp. 825 - 833, http://dx.doi.org/10.1093/ajcn/52.5.825

BROWN AJ; ROBERTS DCK; TRUSWELL AS, 1989, 'FATTY-ACID COMPOSITION OF AUSTRALIAN MARINE FINFISH - A REVIEW', FOOD AUSTRALIA, 41, pp. 655 - &, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1989AA82300024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Brown AJ; Cherikoff V; Roberts DCK, 1987, 'Fatty acid composition of seeds from the Australian Acacia species', Lipids, 22, pp. 490 - 494, http://dx.doi.org/10.1007/BF02540364

Conference Papers

Jun SY; Brown AJ; Yoon J-Y; Lee J-J; Chua NK; Yang JOK; Min J-S; Jang I; Jeon S-J; Choi M-H; Choi T-I; Kim C-H; Kim N-S, 2019, 'Abstract 2769: A squalene epoxidase-cholesterolaxis drives colorectal cancer progression and metastatic dissemination', in Cancer Research, American Association for Cancer Research (AACR), pp. 2769 - 2769, http://dx.doi.org/10.1158/1538-7445.am2019-2769

Sharpe LJ; Prabhu AV; Luu W; Brown AJ, 2016, 'Cholesterol-Mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, CA, San Diego, presented at Experimental Biology Meeting, CA, San Diego, 02 April 2016 - 06 April 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444003020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sharpe LJ; Prabhu AV; Luu W; Brown AJ, 2016, 'Cholesterol-Mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 April 2016 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444006684&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Zerenturk E; Sharpe LJ; Kristiana I; Brown AJ, 2013, 'DHCR24: Unexpected new directions for a terminal step in cholesterol synthesis', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, MA, Boston, presented at Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB), MA, Boston, 20 April 2013 - 24 April 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000319883504279&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Luu W; Sharpe LJ; Stevenson J; Brown AJ, 2013, 'Signalling and cholesterol metabolism', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, MA, Boston, presented at Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB), MA, Boston, 20 April 2013 - 24 April 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000319883503088&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Gill S; Stevenson J; Kristiana I; Brown A, 2011, 'Controlling cholesterol synthesis beyond HMG-CoA reductase', in CHEMISTRY AND PHYSICS OF LIPIDS, ELSEVIER IRELAND LTD, POLAND, Univ Warsaw, Old Library, Warsaw, pp. S6 - S6, presented at 52nd International Conference on the Bioscience of Lipids - Expanding the Horizons of Lipidomics, POLAND, Univ Warsaw, Old Library, Warsaw, 30 August 2011 - 03 September 2011, http://dx.doi.org/10.1016/j.chemphyslip.2011.05.044

Stevenson J; Gill S; Kristiana I; Brown AJ, 2011, 'Cholesterol-Dependent Proteasomal Degradation of Squalene Monooxygenase, a Second Control Point in Cholesterol Synthesis', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, DC, Washington, presented at Experimental Biology Meeting 2011, DC, Washington, 09 April 2011 - 13 April 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310708404685&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Krycer JR; Brown AJ, 2011, 'Crosstalk between the androgen receptor and liver X receptor', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, DC, Washington, presented at Experimental Biology Meeting 2011, DC, Washington, 09 April 2011 - 13 April 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310708406728&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hsieh VW; Gelissen I; Brown AJ; Kim M-J; Kritharides L; Jessup W, 2010, 'Cholesterol-Dependent Posttranslational Control of ABCG1 and ABCA1 Expression', in ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, CA, San Francisco, pp. E282 - E282, presented at Scientific Sessions on Arteriosclerosis, Thrombosis and Vascular Biology, CA, San Francisco, 08 April 2010 - 10 April 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283234800446&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Gelissen I; Harris M; Rye KA; Quinn CM; Brown AJ; Kockx M; Cartland S; Packianathan M; Kritharides L; Jessup W, 2006, 'ABCA1 and ABCG1 act sequentially to mediate cholesterol export to apoA-I', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, ITALY, Rome, pp. 541 - 541, presented at 14th Meeting of the International-Society-of-Atherosclerosis, ITALY, Rome, 18 June 2006 - 22 June 2006, http://dx.doi.org/10.1016/S1567-5688(06)82178-1

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