By Professor Andrew John Brown

Journal articles

Lyons MA; Brown AJ, 2001, '7-Ketocholesterol delivered to mice in chylomicron remnant-like particles is rapidly metabolised, excreted and does not accumulate in aorta', Biochimica Et Biophysica Acta Molecular and Cell Biology of Lipids, 1530, pp. 209 - 218, http://dx.doi.org/10.1016/S1388-1981(01)00083-X

Thomas SR; Leichtweis SB; Pettersson K; Croft KD; Mori TA; Brown AJ; Stocker R, 2001, 'Dietary cosupplementation with vitamin E and coenzyme Q10 inhibits atherosclerosis in apolipoprotein E gene knockout mice', Arteriosclerosis Thrombosis and Vascular Biology, 21, pp. 585 - 593, http://dx.doi.org/10.1161/01.ATV.21.4.585

Lyons MA; Brown AJ, 2001, 'Metabolism of an oxysterol, 7-ketocholesterol, by sterol 27-hydroxylase in HepG2 cells', Lipids, 36, pp. 701 - 711, http://dx.doi.org/10.1007/s11745-001-0775-8

Sleer LS; Brown AJ; Stanley K, 2001, 'Interaction of caveolin with 7-ketocholesterol', Atherosclerosis, 159, pp. 49 - 55

Brown AJ, 2000, 'Atherosclerosis: Cell biology and lipoproteins', Current Opinion in Lipidology, 11, pp. 667 - 669, http://dx.doi.org/10.1097/00041433-200012000-00016

Brown AJ; Watts GF; Burnett JR; Dean RT; Jessup W, 2000, 'Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture', Journal of Biological Chemistry, 275, pp. 27627 - 27633, http://dx.doi.org/10.1074/jbc.M004060200

Brown AJ; Mander EL; Gelissen IC; Kritharides L; Dean RT; Jessup W, 2000, 'Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells: Accumulation of oxidized esters in lysosomes', Journal of Lipid Research, 41, pp. 226 - 236, http://dx.doi.org/10.1016/s0022-2275(20)32056-3

Brown AJ; Mander EL; Gelissen IC; Kritharides L; Dean RT; Jessup W, 2000, 'Accumulation of oxidised esters in lysosomes of macrophage foam cells', Atherosclerosis, 151, pp. 291 - 291, http://dx.doi.org/10.1016/s0021-9150(00)81321-0

Gaus K; Dass CR; Gelissen IC; Kritharides L; Brown AJ; Dean RT; Jessup W, 2000, 'Mechanisms of 7-ketocholesterol-mediated inhibition of cholesterol efflux from human foam cell macrophages', Atherosclerosis, 151, pp. 185 - 185, http://dx.doi.org/10.1016/s0021-9150(00)80842-4

Lyons MA; Brown AJ, 2000, 'Metabolism of 7-ketocholesterol by sterol 27-hydroxylase in human hepatic cells', Atherosclerosis, 151, pp. 291 - 291, http://dx.doi.org/10.1016/s0021-9150(00)81320-9

Rees DM; Kritharides L; Jessup W; Dean RT; Brown AJ, 2000, 'Paradoxical effects of oxysterols on cholesterol efflux and APO E release from foam cell macrophages', Heart, Lung and Circulation, 9, pp. A116 - A116, http://dx.doi.org/10.1046/j.1443-9506.2000.07066.x

Brown AJ; Dean RT; Jessup W, 2000, 'Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture', Atherosclerosis, 151, pp. 291 - 291, http://dx.doi.org/10.1016/s0021-9150(00)81322-2

Brown AJ; Cartland S; Kraemer FB; Dean RT; Jessup W, 1999, 'Oxysterol-regulation of cholesterol esterification and hydrolysis in macrophages', FASEB JOURNAL, 13, pp. A1378 - A1378, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082033400334&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lyons MA; Samman S; Gatto L; Brown AJ, 1999, 'Rapid hepatic metabolism of 7-Ketocholesterol in vivo: Implications for dietary oxysterols', FASEB JOURNAL, 13, pp. A1378 - A1378, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082033400332&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lyons MA; Brown AJ, 1999, '7-Ketocholesterol', International Journal of Biochemistry and Cell Biology, 31, pp. 369 - 375, http://dx.doi.org/10.1016/S1357-2725(98)00123-X

Brown AJ; Jessup W, 1999, 'Oxysterols and atherosclerosis', Atherosclerosis, 142, pp. 1 - 28, http://dx.doi.org/10.1016/S0021-9150(98)00196-8

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1999, 'Oxysterol efflux from macrophage foam cells: The essential role of acceptor phospholipid', Journal of Lipid Research, 40, pp. 1636 - 1646, http://dx.doi.org/10.1016/s0022-2275(20)33409-x

Lyons MA; Samman S; Gatto L; Brown AJ, 1999, 'Rapid hepatic metabolism of 7-ketocholesterol in vivo: Implications for dietary oxysterols', Journal of Lipid Research, 40, pp. 1846 - 1857, http://dx.doi.org/10.1016/s0022-2275(20)34901-4

Alwan CL; Brown AJ; Cooper VA; Samman S, 1999, 'The role of ascorbic acid in the mosaic of coronary heart disease: Lipid metabolism and antioxidant functions', Journal of Clinical Biochemistry and Nutrition, 26, pp. 85 - 98, http://dx.doi.org/10.3164/jcbn.26.85

Brown AJ, 1999, 'What's sex got to do with it?', Current Opinion in Lipidology, 10, pp. 641 - 644, http://dx.doi.org/10.1097/00041433-199912000-00022

Siarakas S; Brown AJ; Murrell WG, 1999, 'Immunological evidence for a bacterial toxin aetiology in sudden infant death syndrome', Pathogens and Disease, 25, pp. 37 - 50, http://dx.doi.org/10.1111/j.1574-695x.1999.tb01325.x

Brown AJ, 1998, 'Paradoxical effects of acute cigarette smoking on plasma antioxidant status in humans', Nutrition Research, 18, pp. 1499 - 1519, http://dx.doi.org/10.1016/S0271-5317(98)00126-2

Gelissen IC; Hochgrebe T; Wilson MR; Easterbrook-Smith SB; Jessup W; Dean RT; Brown AJ, 1998, 'Apolipoprotein J (clusterin) induces cholesterol export from macrophage-foam cells: A potential anti-atherogenic function?', Biochemical Journal, 331, pp. 231 - 237, http://dx.doi.org/10.1042/bj3310231

Fragoso YD; Brown AJ, 1998, 'In vivo metabolism of alpha-tocopherol in lipoproteins and liver: studies on rabbits in response to acute cholesterol loading.', Sao Paulo Medical Journal Revista Paulista De Medicina, 116, pp. 1753 - 1759, http://dx.doi.org/10.1590/S1516-31801998000400003

Lyons MA; Samman S; Brown AJ, 1997, '7-Ketocholesterol and cholesterol incorporated into modified lipoprotein have very different kinetics when injected into rats', ATHEROSCLEROSIS, 134, pp. 30 - 30, http://dx.doi.org/10.1016/S0021-9150(97)88247-0

Gelissen IC; Hochgrebe T; Wilson MR; EasterbrookSmith SB; Jessup W; Dean RT; Brown AJ, 1997, 'Apolipoprotein J (clusterin) induces cholesterol export from macrophage foam cells: A potential anti-atherogenic function?', ATHEROSCLEROSIS, 134, pp. 367 - 367, http://dx.doi.org/10.1016/S0021-9150(97)89866-8

Jessup W; Mander EL; Brown AJ; Gelissen IC; Kritharides L; Dean RT, 1997, 'Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells', ATHEROSCLEROSIS, 134, pp. 231 - 232, http://dx.doi.org/10.1016/S0021-9150(97)89233-7

Brown AJ; Dean RT; Jessup W, 1997, 'Free and esterified oxysterols in human atherosclerotic plaque', ATHEROSCLEROSIS, 134, pp. 210 - 210, http://dx.doi.org/10.1016/S0021-9150(97)89083-1

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1997, 'Phospholipid association with apo A-I stimulates oxysterol efflux from macrophage foam cells', ATHEROSCLEROSIS, 134, pp. 367 - 367, http://dx.doi.org/10.1016/S0021-9150(97)89866-8

Brown AJ; Leong SL; Dean RT; Jessup W, 1997, '7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque', Journal of Lipid Research, 38, pp. 1730 - 1745, http://dx.doi.org/10.1016/s0022-2275(20)37148-0

Samman S; Brown AJ; Beltran C; Singh S, 1997, 'The effect of ascorbic acid on plasma lipids and oxidisability of LDL in male smokers', European Journal of Clinical Nutrition, 51, pp. 472 - 477, http://dx.doi.org/10.1038/sj.ejcn.1600431

Kritharides L; Kus M; Brown AJ; Jessup W; Dean RT, 1996, 'Hydroxypropyl-β-cyclodextrin-mediated efflux of 7-ketocholesterol from macrophage foam cells', Journal of Biological Chemistry, 271, pp. 27450 - 27455, http://dx.doi.org/10.1074/jbc.271.44.27450

Gelissen IG; Brown AJ; Mander EL; Kritharides L; Dean RT; Jessup W, 1996, 'Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol', Journal of Biological Chemistry, 271, pp. 17852 - 17860, http://dx.doi.org/10.1074/jbc.271.30.17852

Gatto LM; Hallen GK; Brown AJ; Samman S, 1996, 'Ascorbic acid induces a favorable lipoprotein profile in women.', Journal of the American College of Nutrition, 15, pp. 154 - 158, http://dx.doi.org/10.1080/07315724.1996.10718581

Brown AJ, 1996, 'Acute effects of smoking cessation on antioxidant status', Journal of Nutritional Biochemistry, 7, pp. 29 - 39, http://dx.doi.org/10.1016/0955-2863(95)00164-6

Brown AJ, 1996, 'Atherosclerosis: cell biology and lipoproteins.', Current Opinion in Lipidology, 7, pp. U162 - U167, http://dx.doi.org/10.1097/00041433-199610000-00019

Brown AJ; Dean RT; Jessup W, 1996, 'Free and esterified oxysterol: Formation during copper-oxidation of low density lipoprotein and uptake by macrophages', Journal of Lipid Research, 37, pp. 320 - 335, http://dx.doi.org/10.1016/s0022-2275(20)37619-7

Brown AJ, 1995, 'Atherosclerosis: cell biology and lipoproteins.', Current Opinion in Lipidology, 6, pp. U47 - U54, http://dx.doi.org/10.1097/00041433-199504000-00015

van Reyk DM; Brown AJ; Jessup W; Dean RT, 1995, 'Batch-to-batch variation of chelex-100 confounds metal-catalysed oxidation. Leaching of inhibitory compounds from a batch of chelex-100 and their removal by a pre-washing procedure', Free Radical Research, 23, pp. 533 - 535, http://dx.doi.org/10.3109/10715769509065274

Brown AJ; Fragoso YD, 1994, 'Tocopherols and carotenes are differently distributed in subfractions of high-density lipoprotein', Biochimica Et Biophysica Acta Bba Lipids and Lipid Metabolism, 1210, pp. 373 - 376, http://dx.doi.org/10.1016/0005-2760(94)90243-7

Riemersma RA; Perkins D; Brown AJ; Brown J, 1994, 'Linoleic acid and coronary artery disease.', American Journal of Clinical Nutrition, 59, pp. 949 - 950, http://dx.doi.org/10.1093/ajcn/59.4.949

Riemersma RA; Perkins D; Brown AJ; Brown J, 1994, 'Linoleic acid and coronary artery disease', The American Journal of Clinical Nutrition, 59, pp. 949 - 949, http://dx.doi.org/10.1093/ajcn/59.4.949

Brown AJ, 1992, 'Atherosclerosis: Cell biology and lipoproteins', Current Opinion in Lipidology, 3, pp. II19 - II20, http://dx.doi.org/10.1097/00041433-199204000-00018

Brown AJ; Roberts DCK, 1991, 'Fish and fish oil intake: Effect on haematological variables related to cardiovascular disease', Thrombosis Research, 64, pp. 169 - 178, http://dx.doi.org/10.1016/0049-3848(91)90116-E

Brown AJ; Pang E; Roberts DCK, 1991, 'Erythrocyte eicosapentaenoic acid versus docosahexaenoic acid as a marker for fish and fish oil consumption', Prostaglandins Leukotrienes and Essential Fatty Acids, 44, pp. 103 - 106, http://dx.doi.org/10.1016/0952-3278(91)90191-7

Brown AJ; Roberts DCK, 1991, 'Moderate fish oil intake improves lipemic response to a standard fat meal: A study in 25 healthy men', Arteriosclerosis Thrombosis and Vascular Biology, 11, pp. 457 - 466

Brown AJ; Pang E; Roberts DCK, 1991, 'Persistent changes in the fatty acid composition of erythrocyte membranes after moderate intake of n-3 polyunsaturated fatty acids: Study design implications', American Journal of Clinical Nutrition, 54, pp. 668 - 673, http://dx.doi.org/10.1093/ajcn/54.4.668

Brown AJ; Roberts DC, 1991, 'The effect of fasting triacylglyceride concentration and apolipoprotein E polymorphism on postprandial lipemia.', Arterioscler Thromb, 11, pp. 1737 - 1744, http://dx.doi.org/10.1161/01.atv.11.6.1737

Brown AJ; Roberts DCK, 1990, 'Erythrocyte EPA as a marker for intake of fish and fish oil', European Journal of Clinical Nutrition, 44, pp. 487 - 488

Brown AJ; Roberts DCK; Pritchard JE; Truswell AS, 1990, 'A mixed Australian fish diet and fish-oil supplementation: Impact on the plasma lipid profile of healthy men', American Journal of Clinical Nutrition, 52, pp. 825 - 833, http://dx.doi.org/10.1093/ajcn/52.5.825

Back to profile page