By Professor Andrew John Brown

Conference Papers

Van Reyk DM; Brown AJ; Hult'en LM; Hart PH; Dean RT; Jessup W, 2002, 'Lipoprotein-delivered oxysterols do not stimulate cytokine production in macrophage foam cells at pathophysiologically relevant levels', in CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, BLACKWELL PUBLISHING ASIA, AUSTRALIA, MELBOURNE, pp. A18 - A18, presented at Joint Symposium of the Australian-Athersclerosis-Society/Australian-Vascular-Biology-Society, AUSTRALIA, MELBOURNE, 27 December 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183582000053&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Quinn CM; Brown AJ; Kritharides L; Jessup W, 2002, 'The expression and regulation of sterol 27-hydroxylase (cyp27) in human macrophages', in CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, BLACKWELL PUBLISHING ASIA, AUSTRALIA, MELBOURNE, pp. A25 - A25, presented at Joint Symposium of the Australian-Athersclerosis-Society/Australian-Vascular-Biology-Society, AUSTRALIA, MELBOURNE, 27 December 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183582000066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Presentations

Moon H; Sharpe L; Choi E; Bielefeldt-Ohmann H; Nassar Z; Parat M-O; Francois M; Lee CS; Brown A; Russell P; Inder K; Hill M, 2014, 'Hypercholesterolemia promotes prostate cancer PC-3 metastases in orthotopic xenograft mice', presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-4950

Conference Abstracts

Chua N; Howe V; Jatana N; Hart-Smith G; Scott N; Thukral L; Brown A, 2020, 'Squalene Monooxygenase at the Nexus between Cholesterol Homeostasis and Proteostasis', in FASEB JOURNAL, WILEY, CA, San Diego, Vol. 34, presented at Annual Meeting on Experimental Biology, CA, San Diego, 04 April 2020 - 07 April 2020, http://dx.doi.org/10.1096/fasebj.2020.34.s1.03280

Scott N; Sharpe L; Capell-Hattam I; Gullo S; Luu W; Brown A, 2020, 'The Cholesterol Synthesis Enzyme Lanosterol 14 alpha-Demethylase is Post-Translationally Regulated by the E3 Ubiquitin Ligase MARCH6', in FASEB JOURNAL, WILEY, CA, San Diego, Vol. 34, presented at Annual Meeting on Experimental Biology, CA, San Diego, 04 April 2020 - 07 April 2020, http://dx.doi.org/10.1096/fasebj.2020.34.s1.03882

Capell-Hattam I; Sharpe L; Qian L; Hart-Smith G; Prabhu A; Brown A, 2020, 'Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally', in FASEB JOURNAL, WILEY, CA, San Diego, Vol. 34, presented at Annual Meeting on Experimental Biology, CA, San Diego, 04 April 2020 - 07 April 2020, http://dx.doi.org/10.1096/fasebj.2020.34.s1.02547

Jun SY; Brown AJ; Yoon J-Y; Lee J-J; Chua NK; Yang JOK; Min J-S; Jang I; Jeon S-J; Choi M-H; Choi T-I; Kim C-H; Kim N-S, 2019, 'A squalene epoxidase-cholesterolaxis drives colorectal cancer progression and metastatic dissemination', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.SABCS18-2769

Luu W; Zerenturk E; Kristiana I; Sharpe L; Brown A, 2015, 'Signaling Regulates Activity of DHCR24, the Final Enzyme in Cholesterol Synthesis', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 29, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361470504086&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Prabhu A; Luu W; Sharpe L; Brown A, 2015, 'The Interplay between Cholesterol and Vitamin D Biosynthesis', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 29, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361470504115&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Preprints

Coates H; Olzomer E; Du X; Farrell R; Yang H; Byrne F; Brown A, 2022, Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase, , http://dx.doi.org/10.1101/2022.08.18.504470

Coates HW; Brown AJ, 2020, The mammalian cholesterol synthesis enzyme squalene monooxygenase is proteasomally truncated to a constitutively active form, , http://dx.doi.org/10.1101/2020.10.12.335414

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