By Professor David Simon Ziegler

Journal articles

Haeusler GM; Dashti SG; James F; Babl FE; Borland ML; Clark JE; Padhye B; Tapp H; Alvaro F; Raj TS; Walwyn T; Ziegler DS; Super L; Hall L; Yeoh DK; Butters C; McMullan B; Hanna DMT; De Abreu Lourenco R; Slavin MA; Phillips B; Thursky KA, 2024, 'Impact of time to antibiotics on clinical outcome in paediatric febrile neutropenia: a target trial emulation of 1685 episodes', The Lancet Regional Health - Western Pacific, 53, http://dx.doi.org/10.1016/j.lanwpc.2024.101226

van Tilburg CM; Kilburn LB; Perreault S; Schmidt R; Azizi AA; Cruz-Martínez O; Zápotocký M; Scheinemann K; Meeteren AYNSV; Sehested A; Opocher E; Driever PH; Avula S; Ziegler DS; Capper D; Koch A; Sahm F; Qiu J; Tsao LP; Blackman SC; Manley P; Milde T; Witt R; Jones DTW; Hargrave D; Witt O, 2024, 'LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration', BMC Cancer, 24, http://dx.doi.org/10.1186/s12885-024-11820-x

Staunton J; Ajuyah P; Harris A; Mayoh C; Wong M; Rumford M; Sullivan PJ; Ekert PG; Fuentes-Bolanos N; Cowley MJ; Lau LMS; Ziegler DS; Barahona P; Manoharan N, 2024, 'Novel paediatric case of a spinal high-grade astrocytoma with piloid features in a patient with Noonan Syndrome', npj Precision Oncology, 8, http://dx.doi.org/10.1038/s41698-024-00734-3

Mazariego C; Daly R; McGill B; Kelada L; McKay S; Hetherington K; Ziegler DS; Wakefield CE; Taylor N, 2024, 'Barriers to access of precision guided therapies for children with high-risk cancer', Pediatric Blood and Cancer, 71, http://dx.doi.org/10.1002/pbc.31147

Salomon R; Li W; Toumari M; Lowe A; Mayoh C; Barahona P; Lau LMS; Staunton J; Jacobson E; Nagabushan S; Manoharan N; Mitchell R; Ong F; Haber M; Ziegler DS; Cowley MJ; Mateos MK, 2024, 'Abstract A044 Enhanced disease detection using single cell RNAseq in children with brain cancer', Cancer Research, 84, pp. A044 - A044, http://dx.doi.org/10.1158/1538-7445.pediatric24-a044

Salomon R; Chen W; Shale C; Toumari M; Lowe A; Li W; Chen J; Bazaz SR; Barahona P; Cui L; Mayoh C; El-Kamand S; Tryell V; Wong-Erasmus M; Lau LMS; Bolanos NF; Cuppen E; Khuong Quang DA; Staunton J; Mateos MK; Trahair T; Haber M; Ziegler DS; Ekert PG; Priestley P; Cowley MJ, 2024, 'Abstract A045 Implementing ultra-sensitive, ctDNA-based liquid biopsy for disease monitoring in paediatric tumours', Cancer Research, 84, pp. A045 - A045, http://dx.doi.org/10.1158/1538-7445.pediatric24-a045

Lau LMS; Khuong-Quang D-A; Staunton J; Sanders N; Sriharan S; Trinder S; Manoharan N; Barahona P; Altekoester A-K; Dias K; Rumford M; Sylvester D; Parhar J; Mateos MK; Wong M; Mayoh C; Cowley MJ; Ekert PG; Haber M; Tyrrell V; Ziegler DS, 2024, 'Abstract B012: Clinical utility of real-time comprehensive molecular profiling in childhood brain tumors', Cancer Research, 84, pp. B012 - B012, http://dx.doi.org/10.1158/1538-7445.pediatric24-b012

Revon-Rivière G; Hetherington K; Siddiqi A; Wong L; Mitchell LG; Connolly D; Morgenstern D; Ziegler DS; Cohen-Gogo S, 2024, 'Abstract B066: Bridging patient reported outcomes and CTCAE to improve supportive care and trial design: The PROptimise initiative', Cancer Research, 84, pp. B066 - B066, http://dx.doi.org/10.1158/1538-7445.pediatric24-b066

Hansford JR; Bouche G; Ramaswamy V; Jabado N; Fonseca A; Moloney S; Gottardo NG; Robinson GW; Gajjar A; Tinkle CL; Fisher PG; Foreman N; Ashley DM; Ziegler DS; Eisenstat DD; Massimino M; Witt O; Bartels U; Rutkowski S; Hargrave D; Fouladi M; Pfister SM; Bouffet E, 2024, 'Comments and Controversies in Oncology: The Tribulations of Trials Developing ONC201.', J Clin Oncol, pp. JCO2400709, http://dx.doi.org/10.1200/JCO.24.00709

Jose J; Choi P; Tsoli M; Gopalakrishnan A; Lee C; Park TII; Ziegler D; Denny W, 2024, 'AB005. Development of tumour specific therapy for treatment of diffuse intrinsic pontine glioma (DIPG)', Chinese clinical oncology, 13, pp. AB005, http://dx.doi.org/10.21037/cco-24-ab005

Lau LMS; Khuong-Quang DA; Mayoh C; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester AK; Fuentes-Bolanos NA; Yeung V; Sullivan A; Omer N; Diamond Y; Jessop S; Battaglia L; Zhukova N; Cui L; Lin A; Gifford AJ; Fleuren EDG; Dalla-Pozza L; Moore AS; Khaw SL; Eisenstat DD; Gottardo NG; Wood PJ; Tapp H; Alvaro F; McCowage G; Nicholls W; Hansford JR; Manoharan N; Kotecha RS; Mateos MK; Lock RB; Tyrrell V; Haber M; Trahair TN; Cowley MJ; Ekert PG; Marshall GM; Ziegler DS, 2024, 'Precision-guided treatment in high-risk pediatric cancers', Nature Medicine, 30, pp. 1913 - 1922, http://dx.doi.org/10.1038/s41591-024-03044-0

Wang YZM; Kaj-Carbaidwala B; Lane A; Agarwal S; Beier F; Bertuch A; Borovsky KA; Brennan SK; Calado RT; Catto LFB; Dufour C; Ebens CL; Fioredda F; Giri N; Gloude N; Goldman F; Hertel PM; Himes R; Keel SB; Koura DT; Kratz CP; Kulkarni S; Liou I; Nakano TA; Nastasio S; Niewisch MR; Penrice DD; Sasa GS; Savage SA; Simonetto DA; Ziegler DS; Miethke AG; Myers KC, 2024, 'Liver disease and transplantation in telomere biology disorders: An international multicenter cohort', Hepatology Communications, 8, pp. e0462, http://dx.doi.org/10.1097/HC9.0000000000000462

Desai K; Rosenberg T; Power P; Manoharan N; Nagabushan S; Green-Murphy A; Ziegler DS; Li Y; Fisher MJ; Chi S, 2024, 'ATRT-11. IRS-III: LONG-TERM FOLLOW-UP SHOWS FAVORABLE OUTCOMES AND DURABLE RESPONSES FOR LOCALIZED ATYPICAL TERATOID RHABDOID TUMOR (ATRT)', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.011

Rayner BS; Samadder A; Holliday H; Chen Y; Nguyen H; Lee A; Liu J; Hayden E; Ogunmodede OS; Rye K-A; Tsoli M; Bertoldo JB; Ziegler DS, 2024, 'DIPG-16. THE BIG AND SMALL OF PROTEIN POST-TRANSLATIONAL MODIFICATIONS: TARGETING SUMOYLATION AND CITRULLINATION IN DIFFUSE MIDLINE GLIOMA', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.069

Holliday H; Khan A; Jayatilleke N; Mayoh C; Ross SE; Guo X; Sanguino YC; Gopalakrishnan A; Ehteda A; Tsoli M; Ziegler DS, 2024, 'DIPG-24. COMBINED EPIGENETIC THERAPY WITH FACT AND BET INHIBITORS REMODELS CHROMATIN AND DISRUPTS ONCOGENIC TRANSCRIPTION IN DIFFUSE MIDLINE GLIOMA', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.077

Tsoli M; Ung C; Upton DH; Venkat P; Salerno A; Pandher R; Mayoh C; Vittorio O; Ziegler DS, 2024, 'DIPG-35. OVERCOMING THE BLOOD-BRAIN BARRIER CHALLENGE IN DIFFUSE MIDLINE GLIOMA', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.088

Khan A; Upton D; Gopalakrishnan A; Chen Y; Tsoli M; Ziegler DS, 2024, 'DIPG-46. TOTAL THERAPY FOR DIFFUSE MIDLINE GLIOMAS: A SEQUENTIAL, INTENSIVE, MULTI-AGENT COMBINATION PLATFORM IS A POTENT TREATMENT STRATEGY', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.099

Hayden E; Dolman EM; Upton DH; Franshaw L; Liu J; Nguyen H; Tsoli M; Guo X; Mayoh C; Rayner BS; Ziegler DS, 2024, 'DIPG-50. TARGETING VULNERABILITIES IN PAEDIATRIC DIFFUSE MIDLINE GLIOMAS: LEVERAGING PLK1 INHIBITION TO EXPLOIT RAS/PI3K PATHWAY DEPENDENCY', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.103

Manoharan N; Cooney T; DeWire-Schottmiller M; Lane A; Nellan A; Leary S; Partap S; Kilburn L; Wright KD; Hummel T; Ziegler DS; Fouladi M; Hoffman LM; Warren KE, 2024, 'DIPG-52. CEREBROSPINAL FLUID DIVERSION DOES NOT PROLONG OVERALL SURVIVAL IN CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.105

Mateos MK; Ajuyah P; Fuentes-Bolanos N; Kamand SE; Barahona P; Altekoester A; Mayoh C; Holiday H; Liu J; Cui L; Pfaff E; Mackay A; Resnick A; Pinese M; Lau LMS; Khuong-Quang D-A; Dias K; Goudie C; Salkeld A; Rokita JL; Jones DTW; Juretic N; Hayden E; Pfister SM; Kramm CM; Blattner-Johnson M; Jabado N; Tsoli M; Vittorio O; Mueller S; Guo Y; Tucker K; Waszak SM; Perreault S; Jones C; Wong-Erasmus M; Cowley MJ; Ziegler DS, 2024, 'DIPG-76. PEDIATRIC PATIENTS WITH DIFFUSE MIDLINE GLIOMA DEMONSTRATE AN UNEXPECTED PREVALENCE OF GERMLINE VARIANTS IN HOMOLOGOUS RECOMBINATION GENES', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.129

Ziegler DS; Hassall T; Valvi S; Cai D, 2024, 'DIPG-84. PHASE 1 DOSE-ESCALATION STUDY OF ACT001 IN PEDIATRIC PATIENTS WITH ADVANCED BRAIN AND SOLID TUMORS SHOWS ACTIVITY IN DIFFUSE MIDLINE GLIOMA (DMG)', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.137

Nagabushan S; Fuentes-Bolanos N; Lau LMS; Rumford M; Warby M; Courtney E; Grant A; Rodriguez M; Solinas A; Ziegler DS; Kellie SJ; Heath J; Ballinger M; Tucker K, 2024, 'HGG-50. LOW GRADE GLIOMA CAUGHT IN TRANSFORMATION: UTILITY OF COMPREHENSIVE GENOMIC PROFILING IN PEDIATRIC LI FRAUMENI SYNDROME ASSOCIATED HIGH-GRADE GLIOMA', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.334

Kline C; Waanders AJ; Ziegler DS; Kilburn LB; Nysom K; van der Lugt J; Hassall TE; Gerber NU; Segal D; Larouche V; Khuong-Quang D-A; Hansford JR; Leary SES; Driever PH; Bailey S; Perreault S; McCowage G; Witt O; Baxter PA; Kang HJ; Han JW; Hargrave D; Franson AT; Oren MY; Toledano H; Abdelbaki MS; Jabado N; Gottardo NG; Whipple NS; Chi SN; Oren L; Tan EEK; Mueller S; Wright KD; Blackman SC; Qiu J; Podesta D; Walter A; Da Costa D; Manley P; McLeod L; Landi DB, 2024, 'LGG-40. TYPE II RAF INHIBITOR TOVORAFENIB IN RELAPSED/REFRACTORY PEDIATRIC LOW-GRADE GLIOMA (PLGG): REVERSIBLE DECREASES IN GROWTH VELOCITY IN THE PHASE 2 FIREFLY-1 TRIAL', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.431

Khan A; Gopalakrishnan A; Liu J; Burns MR; Tsoli M; Ziegler DS, 2024, 'MDB-61. STARVING TUMORS OF POLYAMINES: A NOVEL APPROACH IN TREATING AGGRESSIVE PEDIATRIC MEDULLOBLASTOMA', Neuro-Oncology, 26, http://dx.doi.org/10.1093/neuonc/noae064.510

Valvi S; Manoharan N; Mateos MK; Hassall TEG; Ziegler DS; McCowage GB; Dun MD; Eisenstat DD; Gottardo NG; Hansford JR, 2024, 'Management of patients with diffuse intrinsic pontine glioma in Australia and New Zealand: Australian and New Zealand Children's Haematology/Oncology Group position statement', Medical Journal of Australia, 220, pp. 533 - 538, http://dx.doi.org/10.5694/mja2.52295

Kelada L; Robertson EG; McKay S; McGill BC; Daly R; Mazariego C; Taylor N; Tyedmers E; Armitage N; Evans HE; Wakefield CE; Ziegler DS, 2024, 'Communicating with families of young people with hard-to-treat cancers: Healthcare professionals’ perspectives on challenges, skills, and training', Palliative and Supportive Care, 22, pp. 539 - 545, http://dx.doi.org/10.1017/S1478951523001992

Robertson EG; Hetherington K; Daly R; Donoghoe MW; Handelsman N; Ziegler DS; Wakefield CE, 2024, 'The feasibility and acceptability of collecting psychosocial outcome measures embedded within a precision medicine trial for childhood cancer', Cancer Medicine, 13, http://dx.doi.org/10.1002/cam4.7339

Kline C; Waanders AJ; Ziegler DS; Kilburn LB; Nysom K; van der Lugt J; Hassall TE; Gerber NU; Segal D; Larouche V; Mueller S; Walter A; Manley P; McLeod L; Landi DB, 2024, 'Type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma (pLGG): Reversible decreases in growth velocity in the phase 2 FIREFLY-1 trial.', Journal of Clinical Oncology, 42, pp. 10036 - 10036, http://dx.doi.org/10.1200/jco.2024.42.16_suppl.10036

Evans L; Walker R; MacDiarmid J; Brahmbhatt H; Anazodo A; McCowage G; Gifford AJ; Kavallaris M; Trahair T; Ziegler DS, 2024, 'A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor', Targeted Oncology, 19, pp. 333 - 342, http://dx.doi.org/10.1007/s11523-024-01051-2

Kilburn LB; Khuong-Quang DA; Hansford JR; Landi D; van der Lugt J; Leary SES; Driever PH; Bailey S; Perreault S; McCowage G; Waanders AJ; Ziegler DS; Witt O; Baxter PA; Kang HJ; Hassall TE; Han JW; Hargrave D; Franson AT; Yalon Oren M; Toledano H; Larouche V; Kline C; Abdelbaki MS; Jabado N; Gottardo NG; Gerber NU; Whipple NS; Segal D; Chi SN; Oren L; Tan EEK; Mueller S; Cornelio I; McLeod L; Zhao X; Walter A; Da Costa D; Manley P; Blackman SC; Packer RJ; Nysom K, 2024, 'Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial, (Nature Medicine, (2023), 10.1038/s41591-023-02668-y)', Nature Medicine, 30, pp. 1500, http://dx.doi.org/10.1038/s41591-024-02910-1

Ercan AB; Aronson M; Fernandez NR; Chang Y; Levine A; Liu ZA; Negm L; Edwards M; Bianchi V; Stengs L; Chung J; Al-Battashi A; Reschke A; Lion A; Ahmad A; Lassaletta A; Reddy AT; Al-Darraji AF; Shah AC; Van Damme A; Bendel A; Rashid A; Margol AS; Kelly BL; Pencheva B; Heald B; Lemieux-Anglin B; Crooks B; Koschmann C; Gilpin C; Porter CC; Gass D; Samuel D; Ziegler DS; Blumenthal DT; Kuo DJ; Hamideh D; Basel D; Khuong-Quang DA; Stearns D; Opocher E; Carceller F; Baris Feldman H; Toledano H; Winer I; Scheers I; Fedorakova I; Su JM; Vengoechea J; Sterba J; Knipstein J; Hansford JR; Gonzales-Santos JR; Bhatia K; Bielamowicz KJ; Minhas K; Nichols KE; Cole KA; Penney L; Hjort MA; Sabel M; Gil-da-Costa MJ; Murray MJ; Miller M; Blundell ML; Massimino M; Al-Hussaini M; Al-Jadiry MF; Comito MA; Osborn M; Link MP; Zapotocky M; Ghalibafian M; Shaheen N; Mushtaq N; Waespe N; Hijiya N; Fuentes-Bolanos N; Ahmad O; Chamdine O; Roy P; Pichurin PN; Nyman P; Pearlman R; Auer RC; Sukumaran RK; Kebudi R; Dvir R; Raphael R; Elhasid R; McGee RB; Chami R; Noss R; Tanaka R; Raskin S; Sen S; Lindhorst S; Perreault S; Caspi S; Riaz S, 2024, 'Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study', The Lancet Oncology, 25, pp. 668 - 682, http://dx.doi.org/10.1016/S1470-2045(24)00026-3

Ziegler DS; Lehmann R; Eisenstat DD, 2024, 'A paradigm shift in how we treat pediatric low-grade glioma—Targeting the molecular drivers', Neuro-Oncology, 26, pp. 593 - 595, http://dx.doi.org/10.1093/neuonc/noae008

Jessop SJ; Fuentos-Bolanos N; Mayoh C; Dolman MEM; Tax G; Wong-Erasmus M; Ajuyah P; Tyrell V; Marshall GM; Ziegler DS; Lau LMS, 2024, 'High throughput screening aids clinical decision-making in refractory acute myeloid leukaemia', Cancer Reports, 7, http://dx.doi.org/10.1002/cnr2.2061

Hogarty MD; Ziegler DS; Franson A; Chi YY; Tsao-Wei D; Liu K; Vemu R; Gerner EW; Bruckheimer E; Shamirian A; Hasenauer B; Balis FM; Groshen S; Norris MD; Haber M; Park JR; Matthay KK; Marachelian A, 2024, 'Phase 1 study of high-dose DFMO, celecoxib, cyclophosphamide and topotecan for patients with relapsed neuroblastoma: a New Approaches to Neuroblastoma Therapy trial', British Journal of Cancer, 130, pp. 788 - 797, http://dx.doi.org/10.1038/s41416-023-02525-2

Duchatel RJ; Jackson ER; Parackal SG; Kiltschewskij D; Findlay IJ; Mannan A; Staudt DE; Thomas BC; Germon ZP; Laternser S; Kearney PS; Jamaluddin MFB; Douglas AM; Beitaki T; McEwen HP; Persson ML; Hocke EA; Jain V; Aksu M; Manning EE; Murray HC; Verrills NM; Sun CX; Daniel P; Vilain RE; Skerrett-Byrne DA; Nixon B; Hua S; de Bock CE; Colino-Sanguino Y; Valdes-Mora F; Tsoli M; Ziegler DS; Cairns MJ; Raabe EH; Vitanza NA; Hulleman E; Phoenix TN; Koschmann C; Alvaro F; Dayas CV; Tinkle CL; Wheeler H; Whittle JR; Eisenstat DD; Firestein R; Mueller S; Valvi S; Hansford JR; Ashley DM; Gregory SG; Kilburn LB; Nazarian J; Cain JE; Dun MD; Valdes Mora F, 2024, 'PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma', Journal of Clinical Investigation, 134, pp. e170329, http://dx.doi.org/10.1172/JCI170329

Ross SE; Holliday H; Tsoli M; Ziegler DS; Dinger ME, 2024, 'Abstract B015: RNA N6-methyladenosine (m6A) as a therapeutic target in Diffuse Midline Glioma (DMG)', Cancer Research, 84, pp. B015 - B015, http://dx.doi.org/10.1158/1538-7445.brain23-b015

Holliday H; Khan A; Jayatilleke N; Mayoh C; Ross SE; Sanguino YC; Gopalakrishnan A; Ehteda A; Rayner B; Tsoli M; Ziegler DS, 2024, 'Abstract B016: Targeting the epigenome through combined Facilitates Chromatin Transcription (FACT) and Bromodomain and Extra-Terminal Domain (BET) inhibition in Diffuse Midline Glioma (DMG)', Cancer Research, 84, pp. B016 - B016, http://dx.doi.org/10.1158/1538-7445.brain23-b016

Khan A; Gopalakrishnan A; Liu J; Burns MR; Tsoli M; Ziegler DS, 2024, 'Abstract B047: Inhibition of the polyamine pathway: a novel therapeutic approach to treat aggressive pediatric medulloblastoma', Cancer Research, 84, pp. B047 - B047, http://dx.doi.org/10.1158/1538-7445.brain23-b047

Das A; Fernandez NR; Levine A; Bianchi V; Stengs LK; Chung J; Negm L; Dimayacyac JR; Chang Y; Nobre L; Ercan AB; Sanchez-Ramirez S; Sudhaman S; Edwards M; Larouche V; Samuel D; Van Damme A; Gass D; Ziegler DS; Bielack SS; Koschmann C; Zelcer S; Yalon-Oren M; Campino GA; Sarosiek T; Nichols KE; Loret De Mola R; Bielamowicz K; Sabel M; Frojd CA; Wood MD; Glover JM; Lee YY; Vanan M; Adamski JK; Perreault S; Chamdine O; Hjort MA; Zapotocky M; Carceller F; Wright E; Fedorakova I; Lossos A; Tanaka R; Osborn M; Blumenthal DT; Aronson M; Bartels U; Huang A; Ramaswamy V; Malkin D; Shlien A; Villani A; Dirks PB; Pugh TJ; Getz G; Maruvka YE; Tsang DS; Ertl-Wagner B; Hawkins C; Bouffet E; Morgenstern DA; Tabori U, 2024, 'Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium', Cancer Discovery, 14, pp. 259 - 273, http://dx.doi.org/10.1158/2159-8290.CD-23-0559

Hansford J; Valvi S; de Boer J; McCowage G; Govender D; Kirby M; Ziegler D; Manoharan N; Hassall T; Wainwright B; Alvaro F; Wood PJ; Eisenstat D; Quang DAK; Jenkins M; Dun M; Laughton SJ; Endersby R; Dodgshun A; Gottardo N, 2024, '“If you build it, they will come”: the convergence of funding, research and collaboration in paediatric brain cancer clinical trials', Medical Journal of Australia, http://dx.doi.org/10.5694/mja2.52506

Mazariego CG; McKay S; Tyedmers E; Kelada L; McGill BC; Daly R; Wakefield CE; Ziegler DS; Taylor N; Mazariego-Jones C, 2024, 'Co-design of a paediatric oncology medicines database (ProCure) to support complex care provision for children with a hard-to-treat cancer', Frontiers in Medicine, 11, pp. 1332434, http://dx.doi.org/10.3389/fmed.2024.1332434

Upton DH; Ziegler DS; Tsoli M, 2024, 'Development of Orthotopic Patient-Derived Xenograft Models of Pediatric Intracranial Tumors', , 2806, pp. 75 - 90, http://dx.doi.org/10.1007/978-1-0716-3858-3_7

Rouleau G; Wu K; Ramamoorthi K; Boxall C; Liu RH; Maloney S; Zelmer J; Scott T; Larsen D; Wijeysundera HC; Ziegler D; Bhatia S; Kishimoto V; Gray CS; Desveaux L, 2024, 'Mapping Theories, Models, and Frameworks to Evaluate Digital Health Interventions: Scoping Review', Journal of Medical Internet Research, 26, http://dx.doi.org/10.2196/51098

Chen Y; Khan A; Katsinas C; Michniewicz F; Goldberg J; Franshaw L; Tsoli M; Ziegler DS, 2024, 'Preclinical evaluation of protein synthesis inhibitor omacetaxine in pediatric brainstem gliomas', Neuro-Oncology Advances, 6, http://dx.doi.org/10.1093/noajnl/vdae029

Kilburn LB; Khuong-Quang DA; Hansford JR; Landi D; van der Lugt J; Leary SES; Driever PH; Bailey S; Perreault S; McCowage G; Waanders AJ; Ziegler DS; Witt O; Baxter PA; Kang HJ; Hassall TE; Han JW; Hargrave D; Franson AT; Yalon Oren M; Toledano H; Larouche V; Kline C; Abdelbaki MS; Jabado N; Gottardo NG; Gerber NU; Whipple NS; Segal D; Chi SN; Oren L; Tan EEK; Mueller S; Cornelio I; McLeod L; Zhao X; Walter A; Da Costa D; Manley P; Blackman SC; Packer RJ; Nysom K, 2024, 'The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial', Nature Medicine, 30, pp. 207 - 217, http://dx.doi.org/10.1038/s41591-023-02668-y

Hetherington K; Wakefield CE; McGill BC; Tucker KM; Donoghoe MW; Daly R; Hunter JD; Ballinger M; Fuentes-Bolanos NA; Ziegler DS, 2024, 'When genetics and pediatric cancer collide: Understanding and optimizing families' experiences', Neuro-Oncology Advances, 6, http://dx.doi.org/10.1093/noajnl/vdae133

Lau L; Khoung-Quang DA; Chelsea M; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester AK; Fuentes-Bolanos N; Sullivan A; Mateos M; Tyrrell N; Haber M; Trahair T; Cowley M; Marshall G; Ekert P; Ziegler D, 2024, '438 (PB426): Precision-guided treatment improves outcomes for children with highrisk cancers', European Journal of Cancer, 211, pp. 114946 - 114946, http://dx.doi.org/10.1016/j.ejca.2024.114946

Mayoh C; Gifford AJ; Terry R; Lau LMS; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang DA; Qin V; Mateos MK; Meyran D; Miller KE; Yuksel A; Mould EVA; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore AS; Nicholls W; Gottardo NG; McCowage G; Hansford JR; Khaw SL; Wood PJ; Catchpoole D; Cottrell CE; Mardis ER; Marshall GM; Tyrrell V; Haber M; Ziegler DS; Vittorio O; Trapani JA; Cowley MJ; Neeson PJ; Ekert PG, 2023, 'A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer', Genome Medicine, 15, http://dx.doi.org/10.1186/s13073-023-01170-x

Murray J; Pandher R; Xiao L; Somers K; Brand J; Mosmann E; Alfred S; Kusuma F; Kearns A; Park JR; Marshall LV; Gorrini C; Chesler L; Hogarty MD; Pearson ADJ; Burns M; Fletcher JI; Ziegler D; Norris MD; Haber M, 2023, 'Abstract B132: Addition of AMXT1501 (polyamine uptake inhibitor) plus DFMO (polyamine synthesis inhibitor) to standard-of-care chemotherapy/anti-GD2 antibody in the TH-MYCN mouse neuroblastoma model, enhances efficacy compared to addition of DFMO alone', Molecular Cancer Therapeutics, 22, pp. B132 - B132, http://dx.doi.org/10.1158/1535-7163.targ-23-b132

Poursani EM; Mercatelli D; Raninga P; Bell JL; Saletta F; Kohane FV; Neumann DP; Zheng Y; Rouaen JRC; Jue TR; Michniewicz FT; Schadel P; Kasiou E; Tsoli M; Cirillo G; Waters S; Shai-Hee T; Cazzoli R; Brettle M; Slapetova I; Kasherman M; Whan R; Souza-Fonseca-Guimaraes F; Vahdat L; Ziegler D; Lock JG; Giorgi FM; Khanna KK; Vittorio O, 2023, 'Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer', Cell and Bioscience, 13, http://dx.doi.org/10.1186/s13578-023-01083-7

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