Select Publications

Journal articles

Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640

Franshaw L; Sivarajasingam S; Byrne J; Dalla-Pozza L; Marshall G; Norris M; Ziegler DS, 2016, 'Predictors of success of phase 2 paediatric oncology clinical trials', European Journal of Cancer, 69, pp. S63 - S64, http://dx.doi.org/10.1016/s0959-8049(16)32778-2

Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, 7, pp. 312ra176, http://dx.doi.org/10.1126/scitranslmed.aab1803

Langlois ÉV; Miszkurka M; Zunzunegui MV; Ghaffar A; Ziegler D; Karp I, 2015, 'Inequities in postnatal care in low-and middle-income countries: A systematic review and meta-analysis', Bulletin of the World Health Organization, 93, pp. 259 - 270, http://dx.doi.org/10.2471/BLT.14.140996

Ziegler DS, 2015, 'Never say never', Journal of Clinical Oncology, 33, pp. 518 - 520, http://dx.doi.org/10.1200/JCO.2014.58.7717

Hamasaki T; Lalonde L; Harris P; Bureau NJ; Gaudreault N; Ziegler D; Choinière M, 2015, 'Efficacy of treatments and pain management for trapeziometacarpal (thumb base) osteoarthritis: Protocol for a systematic review', BMJ Open, 5, http://dx.doi.org/10.1136/bmjopen-2015-008904

Whitlock J; dalla Pozza L; Goldberg JM; Silverman LB; Ziegler DS; Attarbaschi A; Brown P; Gardner RA; Gaynon PS; Hutchinson RJ; Marcus LJ; Messinger YH; Schultz KR; Vandergiessen J; Eckroth E; Locatelli F; Zwaan CM; Wood BL; Sposto R; Gore L, 2014, 'Nelarabine in Combination with Etoposide and Cyclophosphamide Is Active in First Relapse of Childhood T-Acute Lymphocytic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LL)', Blood, 124, pp. 795 - 795, http://dx.doi.org/10.1182/blood.v124.21.795.795

Williams P; Wegner E; Ziegler DS, 2014, 'Outcomes in multifocal neuroblastoma as part of the neurocristopathy syndrome', Pediatrics, 134, http://dx.doi.org/10.1542/peds.2013-3340

Quinlan J; Tu MT; Langlois ÉV; Kapoor M; Ziegler D; Fahmi H; Zunzunegui MV, 2014, 'Protocol for a systematic review of the association between chronic stress during the life course and telomere length', Systematic Reviews, 3, http://dx.doi.org/10.1186/2046-4053-3-40

Vedi A; ziegler D, 2014, 'Antibody therapy for pediatric leukemia', Frontiers in Oncology, 4, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2014.00082

Sicotte M; Langlois ÉV; Aho J; Ziegler D; Zunzunegui MV, 2014, 'Association between nutritional status and the immune response in HIV + patients under HAART: Protocol for a systematic review', Systematic Reviews, 3, http://dx.doi.org/10.1186/2046-4053-3-9

Saletta F; Wadham C; Ziegler DS; Marshall GM; Haber M; McCowage G; Norris MD; Byrne JA, 2014, 'Molecular profiling of childhood cancer: Biomarkers and novel therapies', BBA Clinical, 1, pp. 59 - 77, http://dx.doi.org/10.1016/j.bbacli.2014.06.003

Saletta F; Wadham C; Byrne J; Ziegler D; McCowage G; Haber M; Marshall G; Norris M, 2014, '421 Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer', European Journal of Cancer, 50, pp. 135, http://dx.doi.org/10.1016/s0959-8049(14)70547-7

Langlois EV; Miszkurka M; Ziegler D; Karp I; Zunzunegui MV, 2013, 'Protocol for a systematic review on inequalities in postnatal care services utilization in low- and middle-income countries.', Systematic reviews, 2, pp. 55, http://dx.doi.org/10.1186/2046-4053-2-55

Shah S; Schrader KA; Vijai J; Miething C; Hayes J; Klein RJ; Gao X; Kitzing T; Lowe SW; Offit K; Littman J; Offit L; Rau-Murthy R; Fleischut MH; Corines M; Manschreck C; Waanders E; Wei L; Ma J; Chen S-C; Song G; Cheng J; Raimondi SC; Roberts KG; Downing JR; Mullighan CG; Kuiper RP; Simons A; Timms AE; Wechsler J; Horwitz MS; Yang J; Zhang J; Wu G; Rusch M; Nagahawatte P; Meyers P; Bhojwani D; Sandlund JT; Jhanwar S; Murali R; Maslak P; Fleisher M; Murty VV; Schiffman JD; Onel K; Plon SE; Wheeler DA; Ritter D; Ziegler DS; Sutton R; Tucker K; Chenevix-Trench G; Li J; Huntsman DG; Hansford S; Senz J; Walsh T; Lee M; King M-C; Hahn CN; Scott HS; Lo SM; Levine RL; Viale A; Socci ND; Nathanson KL; Daly M; Lipkin SM; Altshuler D, 2013, 'A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia', Nature Genetics, 45, pp. 1226 - 1231, http://dx.doi.org/10.1038/ng.2754

Mateos MK; O'Brien TA; Oswald C; Ziegler DS; Cohn RJ; Russell SJ; Barbaric D; Marshall GM; Trahair TN; Gabriel M, 2013, 'Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review', Pediatric Blood and Cancer, 60, pp. 1520 - 1527, http://dx.doi.org/10.1002/pbc.24559

Ziegler D, 2012, 'Erratum: Treatment of diabetic neuropathy and neuropathic pain: How far have we come? (Diabetes Care (2008) 31 Suppl. 2, (S255-S261) DOI: 10.2337/dc08-s263)', Diabetes Care, 35, pp. 456, http://dx.doi.org/10.2337/dc12-rt02

Argent E; Emder PJ; Monagle P; Mowat DR; Petterson T; Russell SJ; Sachdev RR; Stone C; Ziegler DS, 2012, 'Australian paediatric surveillance unit study of haemoglobinopathies in australian children', Journal of Paediatrics and Child Health, 48, pp. 356 - 360, http://dx.doi.org/10.1111/j.1440-1754.2011.02236.x

Bock V; Ziegler DS; Wargon O; Gray PEA, 2012, 'Neonatal Sweet Syndrome: A potential marker of serious systemic illness', Pediatrics, 129, pp. e1353 - e1359, http://dx.doi.org/10.1542/peds.2011-1854

Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall GM; Norris MD; Haber M; Gamble L, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma', Frontiers in Oncology, 2, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2012.00162

Keating J; Tsoli M; Hallahan AR; Ingram WJ; Haber M; Ziegler DS, 2012, 'Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma', Molecular Cancer Therapeutics, 11, pp. 2654 - 2663, http://dx.doi.org/10.1158/1535-7163.MCT-12-0352

Ziegler D; Rosentock J; Portenoy R, 2011, 'Effective management of diabetic neuropathy - Pregabalin relieves the neuropathic pain', Diabetes Aktuell, 9, pp. 237, http://dx.doi.org/10.1055/s-0031-1286694

Ziegler DS; Keating J; Kesari S; Fast EM; Zawel L; Ramakrishnan N; Barnes J; Kieran MW; Van zanten SEMV; Kung AL, 2011, 'A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo', Neuro - Oncology, 13, pp. 820 - 829, http://dx.doi.org/10.1093/neuonc/nor066

Kamath V; Sugo E; Ziegler DS; Kwok B; Lukeis R, 2011, 'Atypical teratoid/rhaboid tumour arising in association with a pleomorphic xanthoastrocytoma: a case report', Pathology, 43, pp. S76 - S76, http://dx.doi.org/10.1016/s0031-3025(16)33261-5

Barbaro PM; Johnston K; Dalla-Pozza L; Cohn RJ; Wang YA; Marshall GM; Ziegler DS, 2011, 'Reduced incidence of second solid tumors in survivors of childhood Hodgkin's lymphoma treated without radiation therapy', Annals of Oncology, 22, pp. 2569 - 2574, http://dx.doi.org/10.1093/annonc/mdr013

McCowage G; Mrongovius R; Alvaro F; Cohn RJ; Ziegler DS; Oswald CM; White L, 2011, 'Treatment of children with poor risk solid tumors by further escalation of the VETOPEC regimen including very high-dose cyclophosphamide and peripheral stem cell support: An Australian and New Zealand children's hematology and oncology group study', Pediatric Blood and Cancer, 57, pp. 958 - 964, http://dx.doi.org/10.1002/pbc.23042

Ueberberg S; Ziegler D; Schechinger W; Dietrich JW; Akinturk S; Klein HH; Schneider S, 2010, 'In vitro phage display in a rat beta cell line: A simple approach for the generation of a single-chain antibody targeting a novel beta cell-specific epitope', Diabetologia, 53, pp. 1384 - 1394, http://dx.doi.org/10.1007/s00125-010-1725-9

Satharasinghe K; Trahair TN; Barbaric D; O'Brien TA; Russell SJ; Cohn RJ; Marshall GM; Ziegler DS, 2009, 'False-positive MIBG scans with normal computed tomography imaging in patients with high-risk neuroblastoma', Journal of Clinical Oncology, 27, http://dx.doi.org/10.1200/JCO.2009.24.0036

Ziegler DS; Wright RD; Kesari S; Lemieux ME; Tran MA; Jain M; Zawel L; Kung AL, 2008, 'Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins', Journal of Clinical Investigation, 118, pp. 3109 - 3122, http://dx.doi.org/10.1172/JCI34120

Ziegler DS; Kung A; Kieran M, 2008, 'Anti-apoptosis mechanisms in malignant gliomas', Journal of Clinical Oncology, 26, pp. 493 - 500, http://dx.doi.org/10.1200/JCO.2007.13.9717

Ziegler DS; Wright R; Kesari S; Lemieux M; Tran M; Jain M; Zawei L; Kung A, 2008, 'Resistance of human glioblastoma multiformed cells to growth factor inhibitor of apoptosis proteins', The Journal of Clinical Investigation, 2118, pp. 3109 - 3122

Ziegler DS; Klung A, 2008, 'Therapeutic targeting of apoptosis pathways in cancer', Current Opinion Oncology, 20, pp. 97 - 103

Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald CM; Mrongovius R; White L, 2006, 'Efficacy of vincristine and etoposide with escalating cyclophosphamide in poor-prognosis pediatric brain tumors', Neuro - Oncology, 8, pp. 53 - 59

Ziegler DS; McCowage G; Cohn RJ; White L, 2006, 'Long-term survival following a phase I/II trial with VETOPEC for solid tumors in childhood', Journal of Pediatric Hematology and Oncology, 28, pp. 40 - 42

Ziegler DS; Piper AC; Sammut J, 2005, 'Physical injury in young children: The differential diagnosis must include child abuse (vol 41, pg 251, 2005)', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 41, pp. 474 - 474, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231566400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia - Reply', MEDICAL JOURNAL OF AUSTRALIA, 182, pp. 365 - 365, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000229273600017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hocking B; Ziegler DS; Dalla Pozza L; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia (multiple letters) [2]', Medical Journal of Australia, 182, pp. 364 - 365, http://dx.doi.org/10.5694/j.1326-5377.2005.tb06739.x

Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia', Medical Journal of Australia, 182, pp. 364 - 365, http://dx.doi.org/10.5694/j.1326-5377.2005.tb06740.x

Ziegler DS; Dalla Pozza L; Waters K; Marshall GM, 2005, 'Advances in childhood leukaemia: successful clinical-trials research leads to individualised therapy', Medical Journal of Australia, 182, pp. 78 - 81

Ziegler DS; Sammut JF; Piper AC, 2005, 'Assessment and follow up of suspected child abuse in preschool children with fractures seen in a general hospital emergency department.', Journal of Paediatrics and Child Health (Vol. 48, Suppl. 2, 2012, 1–13), 41, pp. 251 - 255

Ziegler DS; Russell SJ; Rozenberg G; James CA; Trahair TN; O'Brien TA, 2005, 'Goats' milk quackery', Journal of Paediatrics and Child Health, 41, pp. 569 - 571

Ziegler DS; Cohn RJ; Duffy B; Sutton R; Norris MD, 2005, 'PCR for monoclonal gene rearrangements can differentiate infantile acute lymphoblastic leukemia from cytomegalovirus infection', Leukemia Research, 29, pp. 111 - 112

Haysom L; Ziegler DS; Cohn RJ; Rosenberg A; Carroll SL; Kainer G, 2005, 'Retinoic acid may increase the risk of bone marrow transplant nephrology', Pediatric Nephrology, 20, pp. 534 - 538

Scanlon DM; Ziegler DS; Mantzouranis EC; Boicos SA; Bagourakis GS, 2003, 'Throat clearing in asthma [5] (multiple letters)', New England Journal of Medicine, 349, pp. 194 - 195, http://dx.doi.org/10.1056/NEJM200307103490220

Ziegler D; Bent G, 2001, 'Caustic-induced upper airway obstruction responsive to nebulized adrenaline [5]', Pediatrics, 107, pp. 807 - 808, http://dx.doi.org/10.1542/peds.107.4.807

Ziegler DS; Bent GP, 2001, 'Upper airway obstruction induced by a caustic substance found responsive to nebulised adrenaline [3]', Journal of Paediatrics and Child Health, 37, pp. 524 - 525, http://dx.doi.org/10.1046/j.1440-1754.2001.0742c.x

Conference Papers

Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG)', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), LA, New Orleans, 08 April 2022 - 13 April 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000892509503338&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG).', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), LA, New Orleans, 08 April 2022 - 13 April 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000892509501275&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Das A; Morgenstern D; Sudhaman S; Coblentz A; Chung J; Stone S; Alsafwani N; Cabric V; Nobre L; Bianchi V; Edwards M; Sambira L; Constantini S; Dvir R; Yalon-Oren M; Campino G; Caspi S; Larouche V; Reddy A; Osborn M; Mason G; Lindhorst S; Bronsema A; Magimairajan V; Opocher E; Mola R; Sabel M; Frojd C; Sumerauer D; Samuel D; Cole K; Chiaravalli S; Massimino M; Tomboc P; Ziegler D; George B; Damme A; Hijiya N; Gass D; Mcgee R; Mordechai O; Bowers D; Laetsch T; Lossos A; Blumenthal D; Sarosiek T; Yen L; Knipstein J; Bendel A; Hoffmann L; Luna-Fineman S; Zimmermann S; Scheers I; Nichols K; Zapotocky M; Hansford J; Maris J; Dirks P; Taylor M; Kulkarni A; Shroff M; Tsang D; Villani A; Aronson M; Durno C; Shlein A; Malkin D; Getz G; Maruvka Y; Ohashi P; Hawkins C; Pugh T; Bouffet E; Tabori U, 2021, 'Mutation and Microsatellite Burden Predict Response to PD-1 Inhibition in Children With Germline DNA Replication Repair Deficiency', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S95 - S96, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000708132100190&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Dodgshun A; Fukuoka K; Edwards M; Bianchi V; Sexton-Oates A; Larouche V; Magimairajan V; Lindhorst S; Yalon M; Mason G; Crooks B; Constantini S; Massimino M; Chiaravalli S; Ramdas J; Mason W; Shamvil A; Farah R; Van Damme A; Opocher E; Hamid SA; Ziegler D; Samuel D; Cole KA; Tomboc P; Stearns D; Thomas G; Lossos A; Sullivan M; Hansford JR; Jones D; Mackay A; Jones C; Ramaswamy V; Hawkins C; Bouffet E; Tabori U, 2020, 'DIAGNOSTIC AND BIOLOGICAL ROLE OF METHYLATION PATTERNS IN REPLICATION REPAIR DEFICIENT HIGH GRADE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 347 - 348, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100308&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1


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