By Professor David Simon Ziegler

Journal articles

Bhojwani D; Burke MJ; Horton T; Ziegler DS; Sulis ML; Schultz KR; Wayne A; Izraeli S; Chang BH, 2017, 'Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group', Pediatric Hematology and Oncology, 34, pp. 355 - 364, http://dx.doi.org/10.1080/08880018.2017.1395937

Sadras T; Heatley SL; Kok CH; McClure BJ; Yeung D; Hughes TP; Sutton R; Ziegler DS; White DL, 2017, 'A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH', Cancer Genetics, 216-217, pp. 86 - 90, http://dx.doi.org/10.1016/j.cancergen.2017.07.008

Baugh J; Bartels U; Leach J; Jones B; Chaney B; Warren KE; Kirkendall J; Doughman R; Hawkins C; Miles L; Fuller C; Hassall T; Bouffet E; Lane A; Hargrave D; Grill J; Hoffman LM; Jones C; Towbin A; Savage SA; Monje M; Li XN; Ziegler DS; Veldhuijzen van Zanten S; Kramm CM; van Vuurden DG; Fouladi M, 2017, 'The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease', Journal of Neuro-Oncology, 132, pp. 323 - 331, http://dx.doi.org/10.1007/s11060-017-2372-5

Lapin DH; Tsoli M; Ziegler DS, 2017, 'Genomic insights into diffuse intrinsic pontine glioma', Frontiers in Oncology, 7, pp. 57, http://dx.doi.org/10.3389/fonc.2017.00057

Valvi S; Ziegler DS, 2017, 'Ganglioglioma arising from desmoplastic medulloblastoma: A case report and review of literature', Pediatrics, 139, http://dx.doi.org/10.1542/peds.2016-1403

Hennika T; Hu G; Olaciregui NG; Barton KL; Ehteda A; Chitranjan A; Chang C; Gifford AJ; Tsoli M; Ziegler DS; Carcaboso AM; Becher OJ, 2017, 'Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models', PLoS ONE, 12, pp. e0169485, http://dx.doi.org/10.1371/journal.pone.0169485

Campbell BB; Angelini P; Fabrizio D; Elvin J; Light N; Bouffet E; Larouche V; Samuel D; Stearns D; Cole K; Opocher E; Thomas G; Sabel M; George B; Ziegler D; Lapierre N; Mason G; Magimajrajan V; Shlien A; Tabori U, 2017, 'IMMU-13. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, 19, pp. iv30 - iv30, http://dx.doi.org/10.1093/neuonc/nox083.123

Durno CA; Aronson M; Edwards M; Ling S; Larouche V; Bronsema A; Osborn M; Stearns D; Cole K; Oren M; Opocher E; Mason GE; Thomas G; Sabel M; George B; Ziegler D; Lindhorst S; Magimairajan V; Laperriere N; Samuel D; Bouffet E; Tabori U, 2017, 'Immune Check Point Inhibitor Treatment for Young Patients with Hypermutant Cancers', Gastroenterology, 152, pp. S141 - S141, http://dx.doi.org/10.1016/s0016-5085(17)30801-6

Krishnan S; Ziegler D; Arnaut V; Martin TG; Kapsner K; Henneberg K; Bausch AR; Dietz H; Simmel FC, 2016, 'Molecular transport through large-diameter DNA nanopores.', Nat Commun, 7, pp. 12787, http://dx.doi.org/10.1038/ncomms12787

Evageliou NF; Haber M; Vu A; Laetsch TW; Murray J; Gamble LD; Cheng NC; Liu K; Reese M; Corrigan KA; Ziegler DS; Webber H; Hayes CS; Pawel B; Marshall GM; Zhao H; Gilmour SK; Norris MD; Hogarty MD, 2016, 'Polyamine antagonist therapies inhibit neuroblastoma initiation and progression', Clinical Cancer Research, 22, pp. 4391 - 4404, http://dx.doi.org/10.1158/1078-0432.CCR-15-2539

Bureau NJ; Ziegler D, 2016, 'Economics of Musculoskeletal Ultrasound', Current Radiology Reports, 4, http://dx.doi.org/10.1007/s40134-016-0169-5

Davis T; Doyle H; Tobias V; Ellison DW; Ziegler DS, 2016, 'Case report of spontaneous resolution of a congenital glioblastoma', Pediatrics, 137, pp. e20151241, http://dx.doi.org/10.1542/peds.2015-1241

Fahed R; Raymond J; Ducroux C; Gentric JC; Salazkin I; Ziegler D; Gevry G; Darsaut TE, 2016, 'Testing flow diversion in animal models: a systematic review', Neuroradiology, 58, pp. 375 - 382, http://dx.doi.org/10.1007/s00234-015-1635-0

Barbaro PM; Ziegler DS; Reddel RR, 2016, 'The wide-ranging clinical implications of the short telomere syndromes', Internal Medicine Journal, 46, pp. 393 - 403, http://dx.doi.org/10.1111/imj.12868

Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640

Franshaw L; Sivarajasingam S; Byrne J; Dalla-Pozza L; Marshall G; Norris M; Ziegler DS, 2016, 'Predictors of success of phase 2 paediatric oncology clinical trials', European Journal of Cancer, 69, pp. S63 - S64, http://dx.doi.org/10.1016/s0959-8049(16)32778-2

Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, 7, pp. 312ra176, http://dx.doi.org/10.1126/scitranslmed.aab1803

Langlois ÉV; Miszkurka M; Zunzunegui MV; Ghaffar A; Ziegler D; Karp I, 2015, 'Inequities in postnatal care in low-and middle-income countries: A systematic review and meta-analysis', Bulletin of the World Health Organization, 93, pp. 259 - 270, http://dx.doi.org/10.2471/BLT.14.140996

Ziegler DS, 2015, 'Never say never', Journal of Clinical Oncology, 33, pp. 518 - 520, http://dx.doi.org/10.1200/JCO.2014.58.7717

Hamasaki T; Lalonde L; Harris P; Bureau NJ; Gaudreault N; Ziegler D; Choinière M, 2015, 'Efficacy of treatments and pain management for trapeziometacarpal (thumb base) osteoarthritis: Protocol for a systematic review', BMJ Open, 5, http://dx.doi.org/10.1136/bmjopen-2015-008904

Whitlock J; dalla Pozza L; Goldberg JM; Silverman LB; Ziegler DS; Attarbaschi A; Brown P; Gardner RA; Gaynon PS; Hutchinson RJ; Marcus LJ; Messinger YH; Schultz KR; Vandergiessen J; Eckroth E; Locatelli F; Zwaan CM; Wood BL; Sposto R; Gore L, 2014, 'Nelarabine in Combination with Etoposide and Cyclophosphamide Is Active in First Relapse of Childhood T-Acute Lymphocytic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LL)', Blood, 124, pp. 795 - 795, http://dx.doi.org/10.1182/blood.v124.21.795.795

Williams P; Wegner E; Ziegler DS, 2014, 'Outcomes in multifocal neuroblastoma as part of the neurocristopathy syndrome', Pediatrics, 134, http://dx.doi.org/10.1542/peds.2013-3340

Quinlan J; Tu MT; Langlois ÉV; Kapoor M; Ziegler D; Fahmi H; Zunzunegui MV, 2014, 'Protocol for a systematic review of the association between chronic stress during the life course and telomere length', Systematic Reviews, 3, http://dx.doi.org/10.1186/2046-4053-3-40

Vedi A; ziegler D, 2014, 'Antibody therapy for pediatric leukemia', Frontiers in Oncology, 4, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2014.00082

Sicotte M; Langlois ÉV; Aho J; Ziegler D; Zunzunegui MV, 2014, 'Association between nutritional status and the immune response in HIV + patients under HAART: Protocol for a systematic review', Systematic Reviews, 3, http://dx.doi.org/10.1186/2046-4053-3-9

Saletta F; Wadham C; Ziegler DS; Marshall GM; Haber M; McCowage G; Norris MD; Byrne JA, 2014, 'Molecular profiling of childhood cancer: Biomarkers and novel therapies', BBA Clinical, 1, pp. 59 - 77, http://dx.doi.org/10.1016/j.bbacli.2014.06.003

Saletta F; Wadham C; Byrne J; Ziegler D; McCowage G; Haber M; Marshall G; Norris M, 2014, '421 Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer', European Journal of Cancer, 50, pp. 135, http://dx.doi.org/10.1016/s0959-8049(14)70547-7

Langlois EV; Miszkurka M; Ziegler D; Karp I; Zunzunegui MV, 2013, 'Protocol for a systematic review on inequalities in postnatal care services utilization in low- and middle-income countries.', Systematic reviews, 2, pp. 55, http://dx.doi.org/10.1186/2046-4053-2-55

Shah S; Schrader KA; Vijai J; Miething C; Hayes J; Klein RJ; Gao X; Kitzing T; Lowe SW; Offit K; Littman J; Offit L; Rau-Murthy R; Fleischut MH; Corines M; Manschreck C; Waanders E; Wei L; Ma J; Chen S-C; Song G; Cheng J; Raimondi SC; Roberts KG; Downing JR; Mullighan CG; Kuiper RP; Simons A; Timms AE; Wechsler J; Horwitz MS; Yang J; Zhang J; Wu G; Rusch M; Nagahawatte P; Meyers P; Bhojwani D; Sandlund JT; Jhanwar S; Murali R; Maslak P; Fleisher M; Murty VV; Schiffman JD; Onel K; Plon SE; Wheeler DA; Ritter D; Ziegler DS; Sutton R; Tucker K; Chenevix-Trench G; Li J; Huntsman DG; Hansford S; Senz J; Walsh T; Lee M; King M-C; Hahn CN; Scott HS; Lo SM; Levine RL; Viale A; Socci ND; Nathanson KL; Daly M; Lipkin SM; Altshuler D, 2013, 'A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia', Nature Genetics, 45, pp. 1226 - 1231, http://dx.doi.org/10.1038/ng.2754

Mateos MK; O'Brien TA; Oswald C; Ziegler DS; Cohn RJ; Russell SJ; Barbaric D; Marshall GM; Trahair TN; Gabriel M, 2013, 'Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review', Pediatric Blood and Cancer, 60, pp. 1520 - 1527, http://dx.doi.org/10.1002/pbc.24559

Ziegler D, 2012, 'Erratum: Treatment of diabetic neuropathy and neuropathic pain: How far have we come? (Diabetes Care (2008) 31 Suppl. 2, (S255-S261) DOI: 10.2337/dc08-s263)', Diabetes Care, 35, pp. 456, http://dx.doi.org/10.2337/dc12-rt02

Argent E; Emder PJ; Monagle P; Mowat DR; Petterson T; Russell SJ; Sachdev RR; Stone C; Ziegler DS, 2012, 'Australian paediatric surveillance unit study of haemoglobinopathies in australian children', Journal of Paediatrics and Child Health, 48, pp. 356 - 360, http://dx.doi.org/10.1111/j.1440-1754.2011.02236.x

Bock V; Ziegler DS; Wargon O; Gray PEA, 2012, 'Neonatal Sweet Syndrome: A potential marker of serious systemic illness', Pediatrics, 129, pp. e1353 - e1359, http://dx.doi.org/10.1542/peds.2011-1854

Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall GM; Norris MD; Haber M; Gamble L, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma', Frontiers in Oncology, 2, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2012.00162

Keating J; Tsoli M; Hallahan AR; Ingram WJ; Haber M; Ziegler DS, 2012, 'Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma', Molecular Cancer Therapeutics, 11, pp. 2654 - 2663, http://dx.doi.org/10.1158/1535-7163.MCT-12-0352

Ziegler D; Rosentock J; Portenoy R, 2011, 'Effective management of diabetic neuropathy - Pregabalin relieves the neuropathic pain', Diabetes Aktuell, 9, pp. 237, http://dx.doi.org/10.1055/s-0031-1286694

Ziegler DS; Keating J; Kesari S; Fast EM; Zawel L; Ramakrishnan N; Barnes J; Kieran MW; Van zanten SEMV; Kung AL, 2011, 'A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo', Neuro - Oncology, 13, pp. 820 - 829, http://dx.doi.org/10.1093/neuonc/nor066

Kamath V; Sugo E; Ziegler DS; Kwok B; Lukeis R, 2011, 'Atypical teratoid/rhaboid tumour arising in association with a pleomorphic xanthoastrocytoma: a case report', Pathology, 43, pp. S76 - S76, http://dx.doi.org/10.1016/s0031-3025(16)33261-5

Barbaro PM; Johnston K; Dalla-Pozza L; Cohn RJ; Wang YA; Marshall GM; Ziegler DS, 2011, 'Reduced incidence of second solid tumors in survivors of childhood Hodgkin's lymphoma treated without radiation therapy', Annals of Oncology, 22, pp. 2569 - 2574, http://dx.doi.org/10.1093/annonc/mdr013

McCowage G; Mrongovius R; Alvaro F; Cohn RJ; Ziegler DS; Oswald CM; White L, 2011, 'Treatment of children with poor risk solid tumors by further escalation of the VETOPEC regimen including very high-dose cyclophosphamide and peripheral stem cell support: An Australian and New Zealand children's hematology and oncology group study', Pediatric Blood and Cancer, 57, pp. 958 - 964, http://dx.doi.org/10.1002/pbc.23042

Ueberberg S; Ziegler D; Schechinger W; Dietrich JW; Akinturk S; Klein HH; Schneider S, 2010, 'In vitro phage display in a rat beta cell line: A simple approach for the generation of a single-chain antibody targeting a novel beta cell-specific epitope', Diabetologia, 53, pp. 1384 - 1394, http://dx.doi.org/10.1007/s00125-010-1725-9

Satharasinghe K; Trahair TN; Barbaric D; O'Brien TA; Russell SJ; Cohn RJ; Marshall GM; Ziegler DS, 2009, 'False-positive MIBG scans with normal computed tomography imaging in patients with high-risk neuroblastoma', Journal of Clinical Oncology, 27, http://dx.doi.org/10.1200/JCO.2009.24.0036

Ziegler DS; Wright RD; Kesari S; Lemieux ME; Tran MA; Jain M; Zawel L; Kung AL, 2008, 'Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins', Journal of Clinical Investigation, 118, pp. 3109 - 3122, http://dx.doi.org/10.1172/JCI34120

Ziegler DS; Kung A; Kieran M, 2008, 'Anti-apoptosis mechanisms in malignant gliomas', Journal of Clinical Oncology, 26, pp. 493 - 500, http://dx.doi.org/10.1200/JCO.2007.13.9717

Ziegler DS; Wright R; Kesari S; Lemieux M; Tran M; Jain M; Zawei L; Kung A, 2008, 'Resistance of human glioblastoma multiformed cells to growth factor inhibitor of apoptosis proteins', The Journal of Clinical Investigation, 2118, pp. 3109 - 3122

Ziegler DS; Klung A, 2008, 'Therapeutic targeting of apoptosis pathways in cancer', Current Opinion Oncology, 20, pp. 97 - 103

Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald CM; Mrongovius R; White L, 2006, 'Efficacy of vincristine and etoposide with escalating cyclophosphamide in poor-prognosis pediatric brain tumors', Neuro - Oncology, 8, pp. 53 - 59

Ziegler DS; McCowage G; Cohn RJ; White L, 2006, 'Long-term survival following a phase I/II trial with VETOPEC for solid tumors in childhood', Journal of Pediatric Hematology and Oncology, 28, pp. 40 - 42

Ziegler DS; Piper AC; Sammut J, 2005, 'Physical injury in young children: The differential diagnosis must include child abuse (vol 41, pg 251, 2005)', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 41, pp. 474 - 474, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231566400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia - Reply', MEDICAL JOURNAL OF AUSTRALIA, 182, pp. 365 - 365, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000229273600017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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