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Select Publications
2019, 'Translating palbociclib to the clinic for DIPG - What is truly achievable?', EBioMedicine, 45, pp. 22, http://dx.doi.org/10.1016/j.ebiom.2019.06.024
,2019, 'Healthcare professionals’ attitudes toward cancer precision medicine: A systematic review', Seminars in Oncology, 46, pp. 291 - 303, http://dx.doi.org/10.1053/j.seminoncol.2019.05.001
,2019, 'A phase I study of LOXO-292, a highly selective RET inhibitor, in pediatric patients with RET-altered cancers.', Journal of Clinical Oncology, 37, pp. TPS10066 - TPS10066, http://dx.doi.org/10.1200/jco.2019.37.15_suppl.tps10066
,2019, 'Activity of larotrectinib in TRK fusion cancer patients with brain metastases or primary central nervous system tumors.', Journal of Clinical Oncology, 37, pp. 2006 - 2006, http://dx.doi.org/10.1200/jco.2019.37.15_suppl.2006
,2019, 'MEDU-38. A CASE SERIES OF CHILDREN WITH EMBRYONAL TUMOR WITH MULTILAYER ROSETTES TREATED WITH A MODIFIED IRS-III CHEMOTHERAPY BACKBONE', Neuro-Oncology, 21, pp. ii111 - ii111, http://dx.doi.org/10.1093/neuonc/noz036.196
,2019, 'Germline deletion of ETV6 in familial acute lymphoblastic leukemia', Blood Advances, 3, pp. 1039 - 1046, http://dx.doi.org/10.1182/bloodadvances.2018030635
,2019, 'Macrophage-derived IL1B and TNFa regulate arginine metabolism in neuroblastoma', Cancer Research, 79, pp. 611 - 624, http://dx.doi.org/10.1158/0008-5472.CAN-18-2139
,2019, 'Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma (Journal of Neuro-Oncology, (2019), 141, 2, (253-263), 10.1007/s11060-018-03038-2)', Journal of Neuro-Oncology, 141, pp. 265, http://dx.doi.org/10.1007/s11060-018-03060-4
,2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, 11, http://dx.doi.org/10.1126/scitranslmed.aau1099
,2019, 'International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma', Journal of Neuro-Oncology, 141, pp. 253 - 263, http://dx.doi.org/10.1007/s11060-018-03038-2
,2019, 'Parents', health care professionals', and scientists' experiences of a precision medicine pilot trial for patients with high-risk childhood cancer: A qualitative study', JCO Precision Oncology, 3, pp. 1 - 11, http://dx.doi.org/10.1200/PO.19.00235
,2019, 'Predictors of Success of Phase II Pediatric Oncology Clinical Trials', Oncologist, 24, pp. e765 - e774, http://dx.doi.org/10.1634/theoncologist.2017-0666
,2019, 'Activity of larotrectinib in TRK fusion cancer patients with primary central nervous system tumours', Annals of Oncology, 30, pp. ix124 - ix124, http://dx.doi.org/10.1093/annonc/mdz431.003
,2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, 19, pp. 1078 - 1087, http://dx.doi.org/10.1080/15384047.2018.1491498
,2018, 'Treatment with nitric oxide in the neonatal intensive care unit is associated with increased risk of childhood cancer', Acta Paediatrica, International Journal of Paediatrics, 107, pp. 2092 - 2098, http://dx.doi.org/10.1111/apa.14436
,2018, 'Unresectable VIP-secreting neuroblastoma: Efficacy of debulking and steroids for symptom control', Pediatric Blood and Cancer, 65, http://dx.doi.org/10.1002/pbc.27358
,2018, 'Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study', Leukemia, 32, pp. 2316 - 2325, http://dx.doi.org/10.1038/s41375-018-0094-0
,2018, 'Increased Survival for Children with Acute Myeloid Leukemia Results from Improved Postrelapse Treatment', Journal of Pediatric Hematology/Oncology, 40, pp. 541 - 547, http://dx.doi.org/10.1097/MPH.0000000000001215
,2018, 'Oral malignant gastrointestinal neuroectodermal tumour with junctional component mimicking mucosal melanoma', Pathology, 50, pp. 648 - 653, http://dx.doi.org/10.1016/j.pathol.2018.07.002
,2018, 'Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma', British Journal of Cancer, 119, pp. 693 - 696, http://dx.doi.org/10.1038/s41416-018-0251-2
,2018, 'Oral malignant gastrointestinal neuroectodermal tumour with junctional component mimicking mucosal melanoma.', Pathology, 50, pp. 648 - 653, http://dx.doi.org/10.1016/j.pathol.2018.07.002
,2018, 'Relative frequency and risk factors for long-term opioid therapy following surgery and trauma among adults: A systematic review protocol', Systematic Reviews, 7, http://dx.doi.org/10.1186/s13643-018-0760-3
,2018, 'Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A collaborative report from the International and European Society for Pediatric Oncology DIPG registries', Journal of Clinical Oncology, 36, pp. 1963 - 1972, http://dx.doi.org/10.1200/JCO.2017.75.9308
,2018, 'Quantitative Measurement of Erythrocyte Aggregation as a Systemic Inflammatory Marker by Ultrasound Imaging: A Systematic Review', Ultrasound in Medicine and Biology, 44, pp. 1303 - 1317, http://dx.doi.org/10.1016/j.ultrasmedbio.2018.02.020
,2018, 'DIPG-69. CHARACTERISTICS OF PATIENTS ≥ 10 YEARS OF AGE WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', Neuro-Oncology, 20, pp. i63 - i63, http://dx.doi.org/10.1093/neuonc/noy059.162
,2018, 'DIPG-70. CLINICAL, RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF CHILDREN <3 YEARS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', Neuro-Oncology, 20, pp. i63 - i63, http://dx.doi.org/10.1093/neuonc/noy059.163
,2018, 'GERM-23. INTRACRANIAL GROWING TERATOMA SYNDROME (IGTS): AN INTERNATIONAL RETROSPECTIVE STUDY', Neuro-Oncology, 20, pp. i88 - i88, http://dx.doi.org/10.1093/neuonc/noy059.270
,2018, 'HGG-20. DNA METHYLATION ANALYSIS OF HIGH-GRADE GLIOMA IN PATIENTS WITH MISMATCH REPAIR DEFICIENCIES', Neuro-Oncology, 20, pp. i92 - i93, http://dx.doi.org/10.1093/neuonc/noy059.292
,2018, 'Too many targets, not enough patients: Rethinking neuroblastoma clinical trials', Nature Reviews Cancer, 18, pp. 389 - 400, http://dx.doi.org/10.1038/s41568-018-0003-x
,2018, 'Genomic landscape of pineoblastoma.', Journal of Clinical Oncology, 36, pp. 2028 - 2028, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.2028
,2018, 'NANT 2012-01: Phase 1 study of DFMO and celecoxib with cyclophosphamide and topotecan for relapsed or refractory high-risk neuroblastoma.', JOURNAL OF CLINICAL ONCOLOGY, 36, http://dx.doi.org/10.1200/JCO.2018.36.15_suppl.10558
,2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738
,2018, 'The development of delta: Using agile to develop a decision aid for pediatric oncology clinical trial enrollment', JMIR Research Protocols, 7, pp. e119, http://dx.doi.org/10.2196/resprot.9258
,2018, 'Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma', Oncotarget, 9, pp. 7541 - 7556, http://dx.doi.org/10.18632/oncotarget.24045
,2017, 'Comprehensive Analysis of Hypermutation in Human Cancer', Cell, 171, pp. 1042 - 1056.e10, http://dx.doi.org/10.1016/j.cell.2017.09.048
,2017, 'PDTM-21. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, 19, pp. vi194 - vi194, http://dx.doi.org/10.1093/neuonc/nox168.785
,2017, 'Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group', Pediatric Hematology and Oncology, 34, pp. 355 - 364, http://dx.doi.org/10.1080/08880018.2017.1395937
,2017, 'A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH', Cancer Genetics, 216-217, pp. 86 - 90, http://dx.doi.org/10.1016/j.cancergen.2017.07.008
,2017, 'The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease', Journal of Neuro-Oncology, 132, pp. 323 - 331, http://dx.doi.org/10.1007/s11060-017-2372-5
,2017, 'Genomic insights into diffuse intrinsic pontine glioma', Frontiers in Oncology, 7, pp. 57, http://dx.doi.org/10.3389/fonc.2017.00057
,2017, 'Ganglioglioma arising from desmoplastic medulloblastoma: A case report and review of literature', Pediatrics, 139, http://dx.doi.org/10.1542/peds.2016-1403
,2017, 'Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models', PLoS ONE, 12, pp. e0169485, http://dx.doi.org/10.1371/journal.pone.0169485
,2017, 'IMMU-13. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, 19, pp. iv30 - iv30, http://dx.doi.org/10.1093/neuonc/nox083.123
,2017, 'Immune Check Point Inhibitor Treatment for Young Patients with Hypermutant Cancers', Gastroenterology, 152, pp. S141 - S141, http://dx.doi.org/10.1016/s0016-5085(17)30801-6
,2016, 'Molecular transport through large-diameter DNA nanopores.', Nat Commun, 7, pp. 12787, http://dx.doi.org/10.1038/ncomms12787
,2016, 'Polyamine antagonist therapies inhibit neuroblastoma initiation and progression', Clinical Cancer Research, 22, pp. 4391 - 4404, http://dx.doi.org/10.1158/1078-0432.CCR-15-2539
,2016, 'Economics of Musculoskeletal Ultrasound', Current Radiology Reports, 4, http://dx.doi.org/10.1007/s40134-016-0169-5
,2016, 'Case report of spontaneous resolution of a congenital glioblastoma', Pediatrics, 137, pp. e20151241, http://dx.doi.org/10.1542/peds.2015-1241
,2016, 'Testing flow diversion in animal models: a systematic review', Neuroradiology, 58, pp. 375 - 382, http://dx.doi.org/10.1007/s00234-015-1635-0
,2016, 'The wide-ranging clinical implications of the short telomere syndromes', Internal Medicine Journal, 46, pp. 393 - 403, http://dx.doi.org/10.1111/imj.12868
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