By Professor David Simon Ziegler

Conference Papers

Ehteda A; Kankean A; Chitranjan A; Tsoli M; Liu J; Shen H; Franshaw L; Joshi S; Chang C; Ager E; Ziegler DS, 2017, 'TRX-E-009-1 IS A NOVEL AND A POTENT THERAPEUTIC AGENT FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 6 - 6, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402766800026&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Burns MR; Fosnaugh K; Palfreyman MG; Gamble L; Murray J; Allan S; Eden G; Sarraf S; Norris M; Ziegler D; Haber M, 2017, 'AMX-513 polyamine depletion therapy inhibits tumor growth and reverses immunosuppression in cancers including MYC-driven neuroblastoma and pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-2006

Ehteda A; Tsoli M; Chitranjan A; Chang C; Simon S; Kankean A; Shen H; Liu J; Haber M; Gudkov A; Ziegler D, 2016, 'COMBINATION OF EPIGENETIC MODIFIERS CBL0137 AND PANOBINOSTAT IS HIGHLY POTENT IN VITRO AND IN VIVO FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 51 - 51, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379749000196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tsoli M; Chang C; Shen H; Liu J; Chintranjan A; Franshaw L; Dilda P; Carcaboso AM; Hogg P; Ziegler D, 2016, 'COMBINED TARGETING OF MITOCHONDRIAL FUNCTION AND mTOR IS A POTENT NOVEL THERAPEUTIC APPROACH FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 51 - 51, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379749000195&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Shen H; Tsoli M; Chang C; Chitranjan A; Liu J; Hau E; Kankean A; Ehteda A; Franshaw L; Valvi S; Ziegler D, 2016, 'DICHLOROACETATE AND METFORMIN COMBINE TO MODULATE GLUCOSE METABOLISM AND POTENTLY SENSITISE DIPG CELLS TO RADIATION THERAPY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 48 - 48, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379749000182&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Valvi S; Tsoli M; Chitranjan A; Shen H; Chang C; Kankean A; Ehteda A; Franshaw L; Liu J; Ziegler D, 2016, 'FENRETINIDE TARGETS THE RTK-PI3K PATHWAY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 52 - 53, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379749000201&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Vedi A; Mitchell R; Shanmuganathan S; Oswald C; Marshall G; Trahair T; Ziegler D, 2016, 'Increased Survival for Children with Acute Myeloid Leukaemia Results from Improved Post-Relapse Treatment', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, pp. S80 - S81

Vedi A; Mitchell R; Oswald C; Marshall GM; Trahair T; Ziegler DS, 2015, 'Increased Use of Allogeneic Transplant in CR2 Improves the Outcome for Children with Acute Myeloid Leukaemia', in BLOOD, AMER SOC HEMATOLOGY, FL, Orlando, presented at 57th Annual Meeting of the American-Society-of-Hematology, FL, Orlando, 05 December 2015 - 08 December 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368020102033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wadham C; Saletta F; Byrne JA; Trahair T; Ziegler DS; McCowage G; Marshall G; Haber M; Norris M, 2015, 'Molecular profiling of relapsed childhood cancer', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, UT, Salt Lake, presented at Meeting of the American-Association-for-Cancer-Research (AACR) Precision Medicine Series - Integrating Clinical Genomics and Cancer Therapy, UT, Salt Lake, 13 June 2015 - 16 June 2015, http://dx.doi.org/10.1158/1557-3265.PMSCLINGEN15-51

Kankean A; Tsoli M; Tsang J; Chitranjan A; Maleki S; McDonald K; Ziegler D, 2015, 'THE ANTI-APOPTOTIC PROTEIN ARC IS OVER-EXPRESSED IN MALIGNANT GLIOMA AND CORRELATES WITH PATIENT OUTCOME', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, pp. 14 - 14, presented at 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Diego, 07 May 2015 - 08 May 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361304800054&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kankean A; Ehteda A; Chitranjan A; Tsoli M; Ager E; Ziegler D, 2015, 'TRILEXIUM INHIBITS THE EXPRESSION OF t-NOX AND IS A NOVEL, POTENTIALLY POTENT THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, pp. 5 - 5, presented at 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Diego, 07 May 2015 - 08 May 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361304800020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Carter DR; Murray J; Cheung BB; Kalla H; Gamble L; Tsang J; Sutton S; Koach J; Syed S; Gifford A; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Purmal A; Ziegler D; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'MYCN and is a therapeutic target in neuroblastoma', in MOLECULAR CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, La Jolla, presented at AACR Special Conference on Myc - From Biology to Therapy, CA, La Jolla, 07 January 2015 - 10 January 2015, http://dx.doi.org/10.1158/1557-3125,MYC15-PRO9

Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Carter D; Oberthur A; Fischer M; Ziegler D; Marshall GM; Gurova K; Burkhart C; Purmal A; Gudkov AV; Norris MD, 2014, 'CBL0137, a novel NFkB suppressor and p53 activator, is highly effective in pre-clinical models of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, European Org Res & Treatment Canc, Barcelona, pp. 135 - 135, presented at 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, SPAIN, European Org Res & Treatment Canc, Barcelona, 18 November 2014 - 21 November 2014, http://dx.doi.org/10.1016/S0959-8049(14)70548-9

Tsoli M; Vanniasinghe A; Luk P; Dilda P; Haber M; Hogg P; Ziegler D, 2014, 'TARGETING MITOCHONDRIA AND CELL METABOLISM AS A NOVEL THERAPEUTIC APPROACH IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, SINGAPORE, Singapore, pp. 47 - 47, presented at 16th International Symposium on Pediatric Neuro-Oncology (ISPNO), SINGAPORE, Singapore, 28 June 2014 - 02 July 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000337924200179&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tsoli M; Luk P; Dilda P; Hogg P; Haber M; Ziegler D, 2013, 'TARGETING MITOCHONDRIA AND METABOLISM AS A NOVEL THERAPEUTIC APPROACH IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, FL, Fort Lauderdale, pp. 21 - 21, presented at 2nd Annual Pediatric Neuro-Oncology Basic and Translational Research Conference, FL, Fort Lauderdale, 16 May 2013 - 17 May 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318570500078&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Norris MD; Gamble LD; Murray J; Purqato S; Miiazzo G; Ashton LJ; Oberthuer A; London WB; Hogarty MD; Fischer M; Ziegler D; Marshall GM; Perini G; Haber M, 2013, 'MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3808

Lee H; Ziegler D, 2012, 'LONGER DURATION OF SYMPTOMS AT DIAGNOSIS IS AN INDEPENDENT PROGNOSTIC FACTOR IN PEDIATRIC DIFFUSE PONTINE INTRINSIC GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CANADA, Toronto, pp. 29 - 29, presented at 15th International Symposium on Pediatric Neuro-Oncology (ISPNO), CANADA, Toronto, 24 June 2012 - 27 June 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308394400109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mateos M; O'Brien TA; Gabriel M; Oswald C; Cohn RJ; Russell S; Ziegler DS; Barbaric D; Vowels M; Maurice L; Senner A; Marshall G; Trahair T, 2011, 'IMPROVED SURVIVAL FOLLOWING ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) FOR PAEDIATRIC ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL): A RETROSPECTIVE REVIEW FROM 1984-2009', in PEDIATRIC BLOOD & CANCER, WILEY PERIODICALS, INC, pp. 817 - 817, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295239600446&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Smee RI; Cohn R; Ziegler D; Kwok B; Johnston H; Bye A; Andrews I; Stening W, 2010, 'A RETROSPECTIVE REVIEW OF CHILDREN TREATED AT THE SYDNEY CHILDREN'S HOSPITAL/PRINCE OF WALES HOSPITAL', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, AUSTRIA, Vienna, pp. II69 - II70, presented at 14th International Symposium on Pediatric Neuro-Oncology, AUSTRIA, Vienna, 20 June 2010 - 23 June 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000278817700314&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald C; Mrongovius R; White F, 2004, 'Efficacy of high-dose cyclophosphamide with etoposide and vinchistine ("VETOPEC") in very high-risk paediatric brain tumours', in NEURO-ONCOLOGY, DUKE UNIV PRESS, MA, Boston, pp. 469 - 469, presented at 11th International Symposium on Pediatric Neuro-Oncology, MA, Boston, 13 June 2004 - 16 June 2004, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224332400610&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Posters

Mondal S; Liu PY; Seneviratne J; De Weck A; Venkat P; Mayoh C; Wu J; Maag J; Chen J; Wong M; Bartonicek N; Khoo P; Jin L; Ludlow LE; Ziegler DS; Trahair T; Mestdagh P; Cheung BB; Li J; Dinger ME; Street I; Zhang XD; Marshall GM; Liu T, 2025, 'The super enhancer-driven long noncoding RNA lncNB promotes neuroblastoma tumorigenesis by interacting with MSI2 protein and is targetable by small molecule compounds', IL, Chicago, Vol. 85, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 25 April 2025 - 30 April 2025, http://dx.doi.org/10.1158/1538-7445.AM2025-2608

Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Abstract 5716: Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG)', Vol. 82, pp. 5716 - 5716, http://dx.doi.org/10.1158/1538-7445.am2022-5716

Conference Presentations

Lau L; Khuong-Quang D-A; Nagabushan S; Senapati A; Barahona P; Ajuyah P; Altekoester A-K; Wong M; Mayoh C; Mould E; Fuentes-Bolanos N; Zhukova N; Cowley M; Ekert P; Tyrrell V; Trahair T; Haber M; Marshall G; Ziegler D, 2021, 'Precision Medicine for High-Risk Paediatric Cancers - Molecular Tumour Board Recommendations and Treatment Responses (Zero Childhood Cancer Program)', https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000708132100110&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Anazodo A; Hau P; Hovey E; Nowak A; Pfister S; Hesketh E; Bhadri V; Koh E; Ziegler D, 2018, 'Personalised targeted therapy for adolescent and young adult medulloblastoma patients.', presented at 3rd Global Adolescent and Young Adult Cancer Congress Program, Sheraton Grand Sydney, 04 December 2018 - 06 December 2018, https://www.eiseverywhere.com/ehome/312967

Conference Abstracts

Murray J; Somers K; Mak C; Alfred S; Brand J; Poon E; Fletcher N; Li P; Thurecht K; Gray J; Pearson AD; Chesler L; Hogarty MD; Giles F; Fletcher J; Ziegler DS; Norris MD; Haber M, 2025, 'The glycogen synthase kinase-3β inhibitor 9-ING-41 in combination with chemoimmunotherapy provides long-term survival in the Th-MYCN mouse model', in MOLECULAR CANCER THERAPEUTICS, AMER ASSOC CANCER RESEARCH, Vol. 24, pp. B79 - B79, http://dx.doi.org/10.1158/1535-7163.TARG-25-B079

Mateos MK; Chuah J; Mitchell L; Mayoh C; Valvi S; Hassall T; Martin M; Hansford JR; Khuong-Quang D-A; Ziegler DS, 2025, 'A Phase 1 trial of Deflexifol™ in pediatric patients with relapsed or refractory brain tumors', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 27, pp. v146 - v146, http://dx.doi.org/10.1093/neuonc/noaf201.0574

Khan A; Gopalakrishnan A; Liu J; Mayoh C; Burns MR; Tsoli M; Ziegler DS, 2025, 'POLYAMINE PATHWAY BLOCKADE SENSITISES MYC-DRIVEN MEDULLOBLASTOMA TO CHEMOTHERAPY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 27, http://dx.doi.org/10.1093/neuonc/noaf193.054

Salomon R; Chen W; Shale C; Toumari M; Lowe A; Li W; Chen J; Razavi-Bazaz S; Barahona P; Cui L; Mayoh C; El-Kamand S; Tyrrell V; Wong-Erasmus M; Lau L; Fuentes-Bolanos N; Cuppen E; Khoung-Quang D-A; Staunton J; Mateos MK; Trahair T; Haber M; Ziegler DS; Ekert P; Priestley P; Cowley M, 2024, 'Individualized-tumor-informed panel approach enables ultra-sensitive ctDNA-based minimal residue disease monitoring for high-risk pediatric cancers', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, Vol. 30, presented at AACR Special Conference in Cancer Research: Liquid Biopsy: From Discovery to Clinical Implementation, CA, San Diego, 13 November 2024 - 16 November 2024, http://dx.doi.org/10.1158/1557-3265.LIQBIOP24-B009

Lau L; Khoung-Quang DA; Chelsea M; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester AK; Fuentes-Bolanos N; Sullivan A; Mateos M; Tyrrell N; Haber M; Trahair T; Cowley M; Marshall G; Ekert P; Ziegler D, 2024, 'Precision-guided treatment improves outcomes for children with high-risk cancers', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, Barcelona, Vol. 211, pp. S162 - S163, presented at 36th European-Organisation-for-Research-and-Treatment-of-Cancer / National-Cancer-Institute / American-Association-for-Cancer-Research Symposium on Molecular Targets and Cancer Therapeutics (EORTC/NCI/AACR), SPAIN, Barcelona, 23 October 2024 - 25 October 2024, http://dx.doi.org/10.1016/j.ejca.2024.114946

Lau LMS; Khuong-Quang D-A; Staunton J; Sanders N; Sriharan S; Trinder S; Manoharan N; Barahona P; Altekoester A-K; Dias K; Rumford M; Sylvester D; Parhar J; Mateos MK; Wong M; Mayoh C; Cowley MJ; Ekert PG; Haber M; Tyrrell V; Ziegler DS, 2024, 'Clinical utility of real-time comprehensive molecular profiling in childhood brain tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-B012

Salomon R; Li W; Toumari M; Lowe A; Mayoh C; Barahona P; Lau LMS; Staunton J; Jacobson E; Nagabushan S; Manoharan N; Mitchell R; Ong F; Haber M; Ziegler DS; Cowley MJ; Mateos MK, 2024, 'Enhanced disease detection using single cell RNAseq in children with brain cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-A044

Tax G; Mao J; Cadiz R; Barhen T; Xie J; Harris J; Bae M; Brown LM; Pazaky K; Gifford AJ; Mayoh C; Mateos MK; Peterziel H; Oehme I; Ziegler DS; Tsoli M; Rayner B; Ekert PG; Dolman MEM, 2024, 'Expanding therapeutic horizons: Unleashing the untapped potential of MEK inhibitor treatment in pediatric cancers', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-B003

Salomon R; Chen W; Shale C; Toumari M; Lowe A; Li W; Chen J; Bazaz SR; Barahona P; Cui L; Mayoh C; El-Kamand S; Tryell V; Wong-Erasmus M; Lau LMS; Bolanos NF; Cuppen E; Dong AKQ; Staunton J; Mateos MK; Trahair T; Haber M; Ziegler DS; Ekert PG; Priestley P; Cowley MJ, 2024, 'Implementing ultra-sensitive, ctDNA-based liquid biopsy for disease monitoring in paediatric tumours', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-A045

Manoharan N; Cooney T; Dewire-Schottmiller M; Lane A; Nellan A; Leary S; Partap S; Kilburn L; Wright KD; Hummel T; Ziegler DS; Fouladi M; Hoffman LM; Warren KE, 2024, 'CEREBROSPINAL FLUID DIVERSION DOES NOT PROLONG OVERALL SURVIVAL IN CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.105

Holliday H; Khan A; Jayatilleke N; Mayoh C; Ross SE; Guo X; Sanguino YC; Gopalakrishnan A; Ehteda A; Tsoli M; Ziegler DS, 2024, 'COMBINED EPIGENETIC THERAPY WITH FACT AND BET INHIBITORS REMODELS CHROMATIN AND DISRUPTS ONCOGENIC TRANSCRIPTION IN DIFFUSE MIDLINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.077

Desai K; Rosenberg T; Power P; Manoharan N; Nagabushan S; Green-Murphy A; Ziegler DS; Li Y; Fisher MJ; Chi S, 2024, 'IRS-III: LONG-TERM FOLLOW-UP SHOWS FAVORABLE OUTCOMES AND DURABLE RESPONSES FOR LOCALIZED ATYPICAL TERATOID RHABDOID TUMOR (ATRT)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.011

Nagabushan S; Fuentes-Bolanos N; Lau LMS; Rumford M; Warby M; Courtney E; Grant A; Rodriguez M; Solinas A; Ziegler DS; Kellie SJ; Heath J; Ballinger M; Tucker K, 2024, 'LOW GRADE GLIOMA CAUGHT IN TRANSFORMATION: UTILITY OF COMPREHENSIVE GENOMIC PROFILING IN PEDIATRIC LI FRAUMENI SYNDROME ASSOCIATED HIGH-GRADE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.334

Tsoli M; Ung C; Upton DH; Venkat P; Salerno A; Pandher R; Mayoh C; Vittorio O; Ziegler DS, 2024, 'OVERCOMING THE BLOOD-BRAIN BARRIER CHALLENGE IN DIFFUSE MIDLINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.088

Mateos MK; Ajuyah P; Fuentes-Bolanos N; El Kamand S; Barahona P; Altekoester A; Mayoh C; Holiday H; Liu J; Cui L; Pfaff E; Mackay A; Resnick A; Pinese M; Lau LMS; Khuong-Quang D-A; Dias K; Goudie C; Salkeld A; Rokita JL; Jones DTW; Juretic N; Hayden E; Pfister SM; Kramm CM; Blattner-Johnson M; Jabado N; Tsoli M; Vittorio O; Mueller S; Guo Y; Tucker K; Waszak SM; Perreault S; Jones C; Wong-Erasmus M; Cowley MJ; Ziegler DS, 2024, 'PEDIATRIC PATIENTS WITH DIFFUSE MIDLINE GLIOMA DEMONSTRATE AN UNEXPECTED PREVALENCE OF GERMLINE VARIANTS IN HOMOLOGOUS RECOMBINATION GENES', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.129

Ziegler DS; Hassall T; Valvi S; Cai D, 2024, 'PHASE 1 DOSE-ESCALATION STUDY OF ACT001 IN PEDIATRIC PATIENTS WITH ADVANCED BRAIN AND SOLID TUMORS SHOWS ACTIVITY IN DIFFUSE MIDLINE GLIOMA (DMG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.137

Khan A; Gopalakrishnan A; Liu J; Burns MR; Tsoli M; Ziegler DS, 2024, 'STARVING TUMORS OF POLYAMINES: A NOVEL APPROACH IN TREATING AGGRESSIVE PEDIATRIC MEDULLOBLASTOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.510

Hayden E; Dolman EM; Upton DH; Franshaw L; Liu J; Nguyen H; Tsoli M; Guo X; Mayoh C; Rayner BS; Ziegler DS, 2024, 'TARGETING VULNERABILITIES IN PAEDIATRIC DIFFUSE MIDLINE GLIOMAS: LEVERAGING PLK1 INHIBITION TO EXPLOIT RAS/PI3K PATHWAY DEPENDENCY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.103

Rayner BS; Samadder A; Holliday H; Chen Y; Nguyen H; Lee A; Liu J; Hayden E; Ogunmodede OS; Rye K-A; Tsoli M; Bertoldo JB; Ziegler DS, 2024, 'THE BIG AND SMALL OF PROTEIN POST-TRANSLATIONAL MODIFICATIONS: TARGETING SUMOYLATION AND CITRULLINATION IN DIFFUSE MIDLINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.069

Khan A; Upton D; Gopalakrishnan A; Chen Y; Tsoli M; Ziegler DS, 2024, 'TOTAL THERAPY FOR DIFFUSE MIDLINE GLIOMAS: A SEQUENTIAL, INTENSIVE, MULTI-AGENT COMBINATION PLATFORM IS A POTENT TREATMENT STRATEGY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.099

Michniewicz F; Cazzoli R; Bell J; Saletta F; Poursani E; Rouaen JR; Shai-Hee T; Vu P; Jue TR; Biery M; Bramberger L; Lim T; Khan A; Giorgi FM; Mercatelli D; Mayoh C; Cirillo G; Macmillan A; Whan R; Barlow CT; Tsoli M; Vitanza N; Berry S; Faridi P; Ziegler D; Vittorio O, 2024, 'A comprehensive approach: Copper chelation therapy modulates epigenetic, kinase signaling and metabolic pathways in diffuse midline gliomas (DMG)', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, Vol. 84, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2024 - 10 April 2024, http://dx.doi.org/10.1158/1538-7445.AM2024-525

Ung C; Upton D; Venkat P; Pandher R; Mayoh C; Tsoli M; Ziegler D, 2023, 'BARRIER TO PROGRESS: DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) INDUCES A TIGHTENED BLOOD-BRAIN BARRIER PHENOTYPE.', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CANADA, Vancouver, Vol. 25, presented at 28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO), CANADA, Vancouver, 15 November 2023 - 19 November 2023

Holliday H; Khan A; Jayatilleke N; Mayoh C; Ross SE; Sanguino YC; Gopalakrishnan A; Ehteda A; Rayner B; Tsoli M; Ziegler DS, 2023, 'Targeting the epigenome through combined Facilitates Chromatin Transcription (FACT) and Bromodomain and Extra-Terminal Domain (BET) inhibition in Diffuse Midline Glioma (DMG)', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MN, Minneapolis, Vol. 84, presented at AACR Special Conference on Brain Cancer, MN, Minneapolis, 19 October 2023 - 22 October 2023, http://dx.doi.org/10.1158/1538-7445.BRAIN23-B016

Nagabushan S; Hamayun M; Fardell JE; Donoghoe M; Bland E; Bye A; Jacobson E; Manoharan N; Ziegler DS; McLoone JK; Johnson AM; Cohn RJ, 2023, 'COGNITIVE, ACADEMIC, AND QUALITY OF LIFE OUTCOMES IN SURVIVORS OF PEDIATRIC LOW-GRADE GLIOMA: CHALLENGING THE 'BENIGN TUMOR' PERCEPTION.', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, DC, Washington, Vol. 25, presented at 7th Pediatric Neuro-Oncology Research Conference, DC, Washington, 22 June 2023 - 24 June 2023, http://dx.doi.org/10.1093/neuonc/noad073.221

Courtney E; Hetherington K; Ajuyah P; Altekoester A-K; Rumford M; Dias K; Sylvester D; Fuentes-Bolanos N; Warby M; Mayoh C; Kirk J; Sullivan A; Wong M; Lau L; Dong AKQ; Ekert P; Cowley M; Wakefield C; Tyrrell V; Haber M; Ziegler D; Tucker K; Barahona P; Pinese M, 2023, 'Tumour profiling frequently informs the interpretation of germline variants arising from paired analysis in children and young people', in EUROPEAN JOURNAL OF HUMAN GENETICS, SPRINGERNATURE, SCOTLAND, Glasgow, Vol. 32, pp. 572 - 572, presented at 56th Annual Conference of the European-Society-of-Human-Genetics (ESHG), SCOTLAND, Glasgow, 10 June 2023 - 13 June 2023

Upton D; George S; Liu J; Misevska K; Nguyen H; Cai DD; Su SY-C; Rayner B; Tsoli M; Ziegler D, 2023, 'ACT001 AND CBL0137: A VIABLE COMBINATION THERAPEUTIC FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 70, pp. S153 - S153

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