By Professor Edna Hardeman

Conference Posters

Suchowerska A; Chen B; Mueller J; Ittner A; Hardeman E; Ittner L; Janitz M; Gunning P; Fath T, 2013, 'Increased levels of actin filaments containing the tropomyosin Tm5NM1 regulate excitotoxicity in the mouse', Vol. 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348705376&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Presentations

Hardeman EC; Yang L; Kee AJ; Polishchuk E; Polishchuk R; Pleines I; Kile B; Weigert R; Gunning PW, 2014, 'A novel actin filament population defined by the tropomyosin Tm4 regulates ER-to-Golgi trafficking.', presented at ASCB/IFCB Meeting, PA, Philadelphia, 06 December 2014 - 10 December 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094104105&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jalilian I; Schevzov G; Fath T; Heu C; Bischof L; Vindin H; Stehn JR; Tate MK; Hardeman EC; Gunning PW, 2014, 'Determining the impact of the actin cytoskeleton on the mechanical properties of cells', presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094106265&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jalilian I; Schevzov G; Fath T; Heu C; Bischof L; Vindin H; Stehn JR; Tate MK; Hardeman EC; Gunning PW, 2014, 'Determining the impact of the actin cytoskeleton on the mechanical properties of cells.', presented at ASCB/IFCB Meeting, PA, Philadelphia, 06 December 2014 - 10 December 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094100060&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Schevzov G; Wang B; Hook JW; Tonthat C; Pleines I; Kile B; Hardeman EC; Gunning PW, 2014, 'Distinct Actin Filament Networks Modulate Different Cell Signalling Pathways Involved in Cell Proliferation and Senescence.', presented at ASCB/IFCB Meeting, PA, Philadelphia, 06 December 2014 - 10 December 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094100056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Schevzov G; Wang B; Hook JW; Tonthat C; Pleines I; Kile B; Hardeman EC; Gunning PW, 2014, 'Distinct Actin Filament Networks Modulate Different Cell Signalling Pathways Involved in Cell Proliferation and Senescence.', presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094106093&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Brayford S; Schevzov G; Hardeman EC; Bear JE; Gunning PW, 2014, 'Tropomyosin 5a/b actin filaments collaborate with arp2/3 actin filaments to regulate cell motility.', presented at ASCB/IFCB Meeting, PA, Philadelphia, 06 December 2014 - 10 December 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094100083&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

Wang Y; Swain A; Stear JH; Bryce NS; Dugina VB; Alieva IB; Cripe TP; Stehn JR; Hardeman EC; Gunning PW, 2017, 'Synergy between anti-tropomyosin and anti-microtubule drugs reveals an interaction between actin and microtubule networks.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, PA, Philadelphia, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), PA, Philadelphia, 02 December 2017 - 06 December 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301293&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Meiring JC; Bryce NS; Stear JH; Hardeman EC; Gunning PW, 2017, 'The tropomyosin isoform composition of cellular actin filaments is not a simple function of relative isoform abundance.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, PA, Philadelphia, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), PA, Philadelphia, 02 December 2017 - 06 December 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301286&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Eslami S; Boysen L; Amorim N; Bould S; Kee A; Lucas C; Johnston K; Hardeman E; Cohn RJ; Barres R; Simar D, 2015, 'Radiation-induced metabolic complications: potential role for the microbiota', Copenhagen, Denmark, presented at Nutrient & Metabolite Sensing, Copenhagen, Denmark, 01 November 2015 - 05 November 2015

Eslami S; Boysen L; Amorim N; Bould S; Kee A; Lucas C; Johnston K; Cohn R; Hardeman E; Barres R; Simar D, (eds.), 2015, 'Metabolic complications in cancer survivors: role of adipose tissue dysfunction', in Metabolic complications in cancer survivors: role of adipose tissue dysfunction, Breckenridge, Colorado, USA, presented at Keystone Symposia: Systems Biology of Lipid Metabolism, Breckenridge, Colorado, USA, 09 February 2015 - 13 February 2015

Kee AJ; Tran L; Yang L; Genel F; Weigert R; Gunning P; Hardeman E, 2013, 'Identification of a novel Golgi-associated actin filament population that is important for maintaining Golgi morphology', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348702023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Stehn JR; Haass NK; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Han MH; Hill TA; McCluskey A; Palmer S; Hardeman EC; Weninger W; Cripe TR; Gunning P, 2012, 'Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1827

Segueira VB; Stehn JR; Haass N; Bonello T; Guven K; Desouza M; Schevzov G; Kottyan G; McCluskey A; Bischof L; Palmer S; Hardeman EC; Allanson M; Reeve V; Weninger W; Cripe TP; Gunning P, 2012, 'Improving the specificity of drugs which target the actin cytoskeleton for cancer therapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-5230

Preprints

Mann Z; Verma S; Chen O; Dunbabin P; Ju RJ; Hu C; Lim Kam Sian TCC; Hardeman EC; Gunning PW; Daly RJ; Duszyc K; Poole K; Yap AS, 2026, The way less obvious: PIEZO1 supports apoptotic cell extrusion by optimizing tissue mechanical tension for homeostasis, http://dx.doi.org/10.64898/2026.06.01.729446

Heydecker M; Chen D; Masedunskas A; Mikolaj M; Narayan K; Chen J; Vishwasrao H; Meckel T; Hardeman E; Gunning P; Weigert R, 2026, Intravital single-molecule imaging reveals cytoskeletal turnover as a driver of membrane remodeling in live animals., http://dx.doi.org/10.64898/2026.02.25.708035

Heydecker M; Shitara A; Chen D; Tran D; Masedunskas A; Tora M; Ebrahim S; Appaduray MA; Galeano Niño JL; Bhardwaj A; Narayan K; Hardeman EC; Gunning PW; Weigert R, 2023, Spatial and Temporal Coordination of Force-generating Actin-based Modules Drives Membrane Remodeling In Vivo., http://dx.doi.org/10.1101/2023.12.04.569944

Abouelezz A; Stefen H; Segerstråle M; Micinski D; Minkeviciene R; Hardeman EC; Gunning PW; Hoogenraad CC; Taira T; Fath T; Hotulainen P, 2019, Tropomyosin Tpm3.1 is Required to Maintain the Structure and Function of the Axon Initial Segment, http://dx.doi.org/10.2139/ssrn.3448139

Latham SL; O’Donnell YE; Girgis-Cook O; Clearwater MS; Bryce NS; Mok ET; Lynn SA; Ni J; Alfred S; Leong H; Quek L-E; Murphy KJ; Pantarelli C; Dragutinovic I; Naeini MM; Thiel C; Cadell A; Phimmachanh M; Sharma R; Millar E; Han JZ; Hastings JF; Köhler M; Brummer T; Young A; O’Toole S; Oakes SR; Hardeman E; Lock J; Kolch W; Taft MH; Nobis M; Goldstein L; Timpson P; Parker BL; Holst J; Gunning PW; Cox TR; Morris JC; Croucher DR, A selective inhibitor of oncogenic JNK signalling perturbs metastatic outgrowth of triple-negative breast cancer through metabolic blockade, http://dx.doi.org/10.1101/2025.04.16.649243

Gan WJ; Giri R; Begun J; Abud HE; Hardeman EC; Gunning PW; Yap AS; Noordstra I, A truncation mutant of adenomatous polyposis coli (APC) impairs apical cell extrusion through elevated epithelial tissue tension, http://dx.doi.org/10.1101/2024.03.06.583801

Rae J; Ferguson C; Ariotti N; Webb RI; Cheng H-H; Mead JL; Riches J; Hunter DJB; Martel N; Baltos J; Christopoulos A; Bryce NS; Cagigas ML; Fonseka S; Hardeman EC; Gunning PW; Gambin Y; Hall T; Parton RG, APEX-Gold: A genetically-encoded particulate marker for robust 3D electron microscopy, http://dx.doi.org/10.1101/2020.10.06.328831

Zhao X; Alibhai D; Walsh T; Tarassova N; Englert M; Birol S; Li Y; Williams C; Neal C; Burkard P; Aitken E; Waller A; Ballester-Beltran J; Gunning P; Hardeman E; Agbani E; Nieswandt B; Hers I; Ghevaert C; Poole A, Highly efficient platelet generation in lung vasculature reproduced by microfluidics, http://dx.doi.org/10.21203/rs.3.rs-2306404/v1

Ross JA; Levy Y; Ripolone M; Kolb JS; Turmaine M; Holt M; Moggio M; Fiorillo C; Lindqvist J; Figeac N; Zammit PS; Jungbluth H; Vissing J; Witting N; Granzier H; Zanoteli E; Hardeman EC; Carina W-P; Ochala J, Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy, http://dx.doi.org/10.1101/518522

Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Hung T; Power C; Hardy P; D. D; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE, Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine, http://dx.doi.org/10.1101/2020.06.04.130872

Genoud S; Chaichim C; Porto RR; Tomanic T; Stefen H; Paric E; Sarkar S; Yoo D; Gao W; Hardeman EC; Gunning PW; Karl T; Power J; Fath T, Knock-out of Tpm4.2/actin filaments alters neuronal signaling, neurite outgrowth and behavioral phenotypes in mice, http://dx.doi.org/10.1101/2025.04.10.648285

Zhao X; Alibhai D; Walsh TG; Tarassova N; Birol SZ; Williams CM; Neil CR; Aitken EW; Waller AK; Ballester-Beltran J; Gunning PW; Hardeman EC; Agbani EO; Hers I; Ghevaert C; Poole AW, Platelet generation from circulating megakaryocytes is triggered in the lung vasculature, http://dx.doi.org/10.1101/2021.11.01.466743

Zhao X; Alibhai D; Walsh T; Tarassova N; Birol S; Williams C; Neil C; Aitken E; Waller A; Ballester-Beltran J; Gunning P; Hardeman E; Agbani E; Hers I; Ghevaert C; Poole A, Platelet generation from circulating megakaryocytes is triggered in the lung vasculature, http://dx.doi.org/10.21203/rs.3.rs-690639/v1

Mann Z; Lim F; Verma S; Nanavati BN; Davies JM; Begun J; Hardeman EC; Gunning PW; Subramanyam D; Yap AS; Duszyc K, Pre-existing tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia, http://dx.doi.org/10.1101/2023.08.31.555652

Redpath GMI; Rae J; Yao Y; Ruan J; Cagigas ML; Whan R; Hardeman EC; Gunning PW; Ananthanarayanan V; Parton RG; Ariotti N, Precision Super-Resolution Cryo-Correlative Light and Electron Microscopy for Rapid <i>in situ</i> Structural Analyses of Optogenetically-Positioned Organelles, http://dx.doi.org/10.2139/ssrn.4309027

Redpath GMI; Rae J; Yao Y; Ruan J; Cagigas ML; Whan R; Hardeman EC; Gunning PW; Ananthanarayanan V; Parton RG; Ariotti NA, Precision super-resolution cryo-correlative light and electron microscopy for rapid in situ structural analyses of optogenetically-positioned organelles, http://dx.doi.org/10.1101/2022.11.22.516823

Abouelezz A; Stefen H; Segerstråle M; Micinski D; Minkeviciene R; Hardeman EC; Gunning PW; Hoogenraad CC; Taira T; Fath T; Hotulainen P, Tropomyosin Tpm3.1 is required to maintain the structure and function of the axon initial segment, http://dx.doi.org/10.1101/711614

Kokkinos J; Sharbeen G; Ignacio RMC; Pandzic E; Youkhana J; Boyer C; Haghighi KS; Gunawarman M; Goldstein D; Gebski V; Pajic M; Pitiyarachchi O; Davis ME; Schulstad G; Arkell OSM; Kopecky C; Gonzales-Aloy E; Erkan M; Morton JP; Kavallaris M; Gunning PW; Hardeman EC; Johns A; Gill AJ; Whan RM; Mawson A; Initiative APCG; McCarroll JA; Phillips PA, βIII-Tubulin is a Brake on Extrinsic Cell-Death in Pancreatic Cancer, http://dx.doi.org/10.1101/2022.09.29.510034

Other

O'Mahoney JV; Guven KL; Lin J; Joya JE; Robinson CS; Wade RP; Hardeman EC, 2000, Erratum: Identification of a novel slow-muscle-fiber enhancer binding protein, musTRD1 (Molecular and Cellular Biology (1998) 18:11 (6641-6652)), http://dx.doi.org/10.1128/MCB.20.14.5361-5361.2000

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