By Professor Edna Hardeman

Journal articles

Domazetovska A; Ilkovski B; Cooper ST; Ghoddusi M; Hardeman EC; Minamide LS; Gunning PW; Bamburg JR; North K, 2007, 'Mechanisms underlying intranuclear rod formation', Brain, 130, pp. 3275 - 3284

Chen W; Ruell PA; Ghoddusi M; Kee A; Hardeman EC; Hoffman KM; Thompson MW, 2007, 'Ultrastructural changes and SR Ca2+ regulation in red vastus muscle following eccentric exercise in the rat', Experimental Physiology, 92, pp. 437 - 447, http://dx.doi.org/10.1113/expphysiol.2006.036442

Butler TL; Au CG; Yang B; Egan JR; Tan YM; Hardeman EC; North KN; Verkman AS; Winlaw DS, 2006, 'Cardiac aquaporin expression in humans, rats, and mice', American Journal of Physiology - Heart and Circulatory Physiology, 291, pp. H705 - H713, http://dx.doi.org/10.1152/ajpheart.00090.2006

McGrath MJ; Cottle DL; Nguyen MA; Coghill ID; Robinson PA; Holdsworth M; Cowling BS; Hardeman EC; Mitchell CA; Brown S, 2006, 'Four and a half LIM protein 1 binds myosin binding protein C and regulates myosin filament formation and sarcomere assembly', The Journal of Biological Chemistry, 281, pp. 7666 - 7683

Issa LL; Palmer SJ; Guven KL; Santucci N; Hodgson VRM; Popovic K; Joya JE; Hardeman EC, 2006, 'MusTRD can regulate postnatal fiber-specific expression', Developmental Biology, 293, pp. 104 - 115, http://dx.doi.org/10.1016/j.ydbio.2006.01.019

Sanoudou D; Corbett MA; Han M; Ghoddusi M; Nguyen MA; Vlahovich N; Hardeman EC; Beggs AH, 2006, 'Skeletal muscle repair in a mouse model of nemaline myopathy', Human Molecular Genetics, 15, pp. 2603 - 2612

Vlahovich N; Elmir S; Schevzov G; Kee A; Gunning P; Hardeman E, 2005, 'Non-muscle tropomyosins define functionally distinct microfilament populations in developing skeletal muscle', MECHANISMS OF DEVELOPMENT, 122, pp. S49 - S49, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100178&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Molero JC; Jensen TE; Withers PC; Couzens M; Herzog H; Thien CBF; Langdon WY; Walder K; Murphy MA; Bowtell DDL; Hardeman E; Ghoddusi M; James DE; Cooney GJ, 2005, 'Erratum: c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action (Journal of Clinical Investigation (2004) 114 (1326-1333) (doi:10.1172/JCI200421480))', Journal of Clinical Investigation, 115, pp. 476, http://dx.doi.org/10.1172/JCI200521480C1

Corbett MA; Akkari AP; Domazetovska A; Cooper ST; North K; Laing NG; Gunning PW; Hardeman EC, 2005, 'An alphatropomyosin mutation alters dimer preference in nemaline myopathy', Annals of Neurology, 57, pp. 42 - 49

Molero JC; Jensen TE; Withers PC; Couzens M; Herzog H; Thien CB; Langdon WY; Walder K; Murphy MA; Bowtell DL; Hardeman E; Ghoddusi M; James DE; Cooney GJ, 2005, 'c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action', The Journal of Clinical Investigation, 114, pp. 1326 - 1333, http://dx.doi.org/10.1172/JCI200421480

Molero JC; Jensen T; Withers P; Couzens M; Herzog H; Thien C; Langdon WY; Walder K; Murphy M; Bowtell D; Hardeman E; Ghoddusi M; James DE; Cooney GJ, 2005, 'Erratum: c-Cbl-deficient mice have reduced adiposity, higher energy expenditure,and improved peripheral insulin action (vol 114, pg 1326, 2004)', Journal of Clinical Investigation, 115, pp. 476 - 476, http://dx.doi.org/10.1172/JCI21480C1

Schevzov G; Bryce NS; Almonte-Baldonado R; Joya J; Lin JJ; Hardeman E; Weinberger R; Gunning P, 2005, 'Specific features of neuronal size and shape are regulated by tropomyosin isoforms.', Molecular Biology of the Cell, 16, pp. 3425 - 3437, http://dx.doi.org/10.1091/mbc.E04-10-0951

Gunning PW; Schevzov G; Kee AJ; Hardeman EC, 2005, 'Tropomyosin isoforms: divining rods for actin cytoskeleton function', Trends in Cell Biology, 15, pp. 333 - 341, http://dx.doi.org/10.1016/j.tcb.2005.04.007

Cooper ST; Maxwell AL; Kizana E; Ghoddusi M; Hardeman EC; Alexander IE; Allen DG; North KN, 2004, 'C2C12 co-culture on a fibroblast substratum enables sustained survival of contractile, highly differentiated myotubes with peripheral nuclei and adult fast myosin expression', Cell Motility and the Cytoskeleton, 58, pp. 200 - 211

Joya JE; Kee A; Nair-Shalliker V; Ghoddusi M; Nguyen MAT; Luther P; Hardeman EC, 2004, 'Muscle weakness in a mouse model of nemaline myopathy can be reversed with exercise and reveals a novel myofiber repair mechanism', Human Molecular Genetics, 13, pp. 2633 - 2645, http://dx.doi.org/10.1093/hmg/ddh285

Nair-Shalliker V; Kee A; Lucas C; Joya JE; Hoh JF; Hardeman EC, 2004, 'Myofiber adaptational response to exercise in a mouse model of nemaline myopathy', Muscle and Nerve, 30, pp. 470 - 480, http://dx.doi.org/10.1002/mus.20138

Kee AJ; Schevzov G; Nair-shaliker V; Robinson C; Vrhovski B; Ghoddusi M; Qiu M; Lin JJ; Weinberger R; Gunning P; Hardeman E, 2004, 'Sorting of a nonmuscle tropomyosin to a novel cytoskeletal compartment in skeletal muscle results in muscular dystrophy.', Journal of Cell Biology, 166, pp. 685 - 696

Polly P; Haddadi L; Issa LL; Subramaniam N; Palmer S; Tay ES; Hardeman EC, 2003, 'hMusTRD1α1 Represses MEF2 Activation of the Troponin I Slow Enhancer', The Journal of Biological Chemistry, 278, pp. 36603 - 36610, http://dx.doi.org/10.1074/jbc.M212814200

Tay ES; Guven KL; Subramaniam N; Polly P; Issa LL; Gunning PW; Hardeman EC, 2003, 'Regulation of alternative splicing of Gtf2ird1 and its impact on slow muscle promoter activity', Biochemical Journal, 374, pp. 359 - 367, http://dx.doi.org/10.1042/BJ20030189

Bryce N; Schevzov G; Ferguson V; Percival J; Lin JJ; Matsumura F; Bamburg J; Jeffrey P; Hardeman E; Gunning P; Weinberger R, 2003, 'Specification of actin filament function and molecular composition by tropomyosin isoforms.', Molecular Biology of the Cell, 14, pp. 1002 - 1016

de Haan A; van der Vliet MR; Gommans IM; Hardeman EC; van Engelen BG, 2002, 'Skeletal muscle of mice with a mutation in slow α-tropomyosin is weaker at lower lengths', Neuromuscular Disorders, 12, pp. 952 - 957, http://dx.doi.org/10.1016/S0960-8966(02)00138-4

Corbett MA; Robinson CS; Yang N; Joya JE; Stewart AW; Schnell C; Gunning PW; North KN; Hardeman E, 2001, 'A mutation in alpha-tropomyosin(slow) affects muscle strength, maturation and hypertrophy in a mouse model for nemaline myopathy', Human Molecular Genetics, 10, pp. 317 - 328

Gunning P; Ferguson V; Brennan KJ; Hardeman EC, 2001, 'Alpha-skeletal actin induces a subset of muscle genes independently of muscle differentiation and withdrawal from the cell cycle', Journal of Cell Science, 114, pp. 513 - 524

Ilkovski B; Cooper ST; Nowak K; Ryan MM; Yang N; Schnell C; Durling HJ; Roddick LG; Wilkinson I; Kornberg AJ; Collins KJ; Wallace G; Gunning PW; Hardeman E; North K, 2001, 'Nemaline myopathy caused by mutations in the muscle alpha-skeletal-actin gene', American Journal of Human Genetics, 68, pp. 1333 - 1343

De Iongh RU; Lovicu FJ; Overbeek PA; Schneider MD; Joya JE; Hardeman E; McAvoy JW, 2001, 'Requirement for TGFβ receptor signaling during terminal lens fiber differentiation', Development, 128, pp. 3995 - 4010

Wadhwa R; Sugihara T; Yoshida A; Duncan EL; Hardeman E; Nomura H; Reddel RR; Kaul SC, 1999, 'Cloning and characterization of a novel gene, striamin, that interacts with the tumor suppressor protein p53', The Journal of Biological Chemistry, 274, pp. 14948 - 14955

Gunning P; Hardeman E; Jeffrey P; Weinberger R, 1998, 'Creating intracellular structural domains: spatial segregation of actin and tropomyosin isoforms in neurons', BioEssays, 20, pp. 892 - 900

O'Mahoney JV; Guven KL; Lin J; Joya JE; Robinson CS; Wade RP; Hardeman EC, 1998, 'Identification of a novel slow-muscle-fiber enhancer binding protein, MusTRD1', Molecular and Cellular Biology, 18, pp. 6641 - 6652, http://mcb.asm.org/content/18/11/6641.abstract

Gunning P; Weinberger R; Jeffrey P; Hardeman E, 1998, 'Isoform sorting and the creation of intracellular compartments', Annual Review of Cell and Developmental Biology, 14, pp. 339 - 372

Criswell DS; Hodgson VR; Hardeman EC; Booth FW, 1998, 'Nerve-responsive troponin I slow promoter does not respond to unloading', Journal of Applied Physiology, 84, pp. 1083 - 1087

Criswell DS; Hodgson VRM; Hardeman EC; Booth FW, 1998, 'THE NERVE-RESPONSIVE TROPONIN-I SLOW PROMOTER DOES NOT RESPOND TO UNLOADING', Medicine & Science in Sports & Exercise, 30, pp. 143 - 143, http://dx.doi.org/10.1097/00005768-199805001-00810

Newlands S; Levitt LK; Robinson CS; Karpf AB; Hodgson VR; Wade RP; Hardeman EC, 1998, 'Transcription occurs in pulses in muscle fibers', Genes and Development, 12, pp. 2748 - 2758

Collins T; Joya JE; Arkell RM; Ferguson V; Hardeman EC, 1997, 'Reappearance of the minor α-sarcomeric actins in postnatal muscle', American Journal of Physiology - Cell Physiology, 273, http://dx.doi.org/10.1152/ajpcell.1997.273.6.c1801

Gunning P; Ferguson V; Brennan K; Hardeman E, 1997, 'Impact of α-Skeletal Actin but not α-Cardiac Actin on Myoblast Morphology', Cell Structure and Function, 22, pp. 173 - 179

Collins T; Joya JE; Arkell RM; Ferguson V; Hardeman EC, 1997, 'Reappearance of the minor alpha-sarcomeric actins in postnatal muscle.', Am J Physiol, 273, pp. C1801 - C1810, http://dx.doi.org/10.1152/ajpcell.1997.273.6.C1801

Collins T; Joya JE; Arkell RM; Ferguson V; Hardeman EC, 1997, 'Reappearance of the minor α-sarcomeric actins in postnatal muscle', American Journal of Physiology - Cell Physiology, 273, pp. C1801 - C1810

Coumans JV; Yeoh T; Seeto RK; Keogh A; Brennan K; Gunning P; Hardeman E; Dos Remedios CG, 1997, 'Variations in relative mRNA levels of actin and myosin heavy chains do not produce corresponding differences in their proteins in the adult human heart', Journal of Molecular and Cellular Cardiology, 29, pp. 895 - 905

Dos Remedios CG; Berry DA; Carter LK; Coumans JV; Heinke MY; Kiessling PC; Seeto RK; Thorvaldson T; Trahair T; Yeoh T; Gunning PW; Hardeman E; Humphery-Smith I; Naidoo D; Keogh A, 1996, 'Different electrophoretic techniques produce conflicting data in the analysis of myocardial samples from dilated cardiomyopathy patients: protein levels do not necessarily reflect mRNA levels', Electrophoresis, 17, pp. 235 - 238

Corin SJ; Levitt LK; O'Mahoney JV; Joya JE; Hardeman EC; Wade R, 1995, 'Delineation of a slow-twitch-myofiber-specific transcriptional element by using in vivo somatic gene transfer', Proceedings of the National Academy of Sciences of the United States of America, 92, pp. 6185 - 6189, http://dx.doi.org/10.1073/pnas.92.13.6185

ESSER K; BRENNAN K; HARDEMAN E, 1995, 'WEIGHT-BEARING ACTIVITY, IN ADDITION TO INNERVATION, IS NECESSARY FOR THE ACQUISITION OF A SLOW CONTRACTILE PROTEIN MESSENGER-RNA PROFILE DURING REGENERATION', FASEB JOURNAL, 9, pp. A655 - A655, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995QM40600178&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

ESSER KA; HARDEMAN EC, 1995, 'CHANGES IN CONTRACTILE PROTEIN MESSENGER-RNA ACCUMULATION IN RESPONSE TO SPACEFLIGHT', AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 268, pp. C466 - C471, http://dx.doi.org/10.1152/ajpcell.1995.268.2.C466

Esser KA; Hardeman EC, 1995, 'Changes in contractile protein mRNA accumulation in response to spaceflight', American Journal of Physiology - Cell Physiology, 268, http://dx.doi.org/10.1152/ajpcell.1995.268.2.c466

Zhu L; Lyons GE; Juhasz O; Joya JE; Hardeman EC; Wade R, 1995, 'Developmental Regulation of Troponin I Isoform Genes in Striated Muscles of Transgenic Mice', Developmental Biology, 169, pp. 487 - 503, http://dx.doi.org/10.1006/dbio.1995.1163

Levitt LK; O'mahoney JV; Brennan KJ; Joya JE; Zhu L; Wade RP; Hardeman EC, 1995, 'The Human Troponin I Slow Promoter Directs Slow Fiber-Specific Expression in Transgenic Mice', DNA and Cell Biology, 14, pp. 599 - 607, http://dx.doi.org/10.1089/dna.1995.14.599

Dunwoodie SL; Joya JE; Arkell RM; Hardeman EC, 1994, 'Multiple regions of the human cardiac actin gene are necessary for maturation-based expression in striated muscle', Journal of Biological Chemistry, 269, pp. 12212 - 12219

Esser K; Fauteck S; Kandarlan S; Hardeman E, 1994, '529 MYOSIN HEAVY CHAIN PROTEIN AND mRNA EXPRESSION IN RESPONSE TO SPACEFLIGHT', Medicine & Science in Sports & Exercise, 26, pp. S94 - S94, http://dx.doi.org/10.1249/00005768-199405001-00530

Esser K; Gunning P; Hardeman E, 1993, 'Nerve-dependent and -independent patterns of mRNA expression in regenerating skeletal muscle', Developmental Biology, 159, pp. 173 - 183, http://dx.doi.org/10.1006/dbio.1993.1231

Brennan KJ; Hardeman EC, 1993, 'Quantitative analysis of the human α-skeletal actin gene in transgenic mice', Journal of Biological Chemistry, 268, pp. 719 - 725

Sutherland CJ; Esser KA; Elsom VL; Gordon ML; Hardeman EC, 1993, 'Identification of a program of contractile protein gene expression initiated upon skeletal muscle differentiation', Developmental Dynamics, 196, pp. 25 - 36, http://dx.doi.org/10.1002/aja.1001960104

Hailstones D; Barton P; Chan-Thomas P; Sasse S; Sutherland C; Hardeman E; Gunning P, 1992, 'Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development', Journal of Biological Chemistry, 267, pp. 23295 - 23300

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