By Professor Herbert Herzog

Journal articles

Denton CP; Evans LA; Shiwen XU; Abraham DJ; De Crombrugghe B; Black CM, 2003, 'A Novel Transgenic Mouse Model for Systemic Sclerosis with Balanced Upregulation of Tgfβ Signalling Pathways', Clinical Science, 104, pp. 1P - 1P, http://dx.doi.org/10.1042/cs104001pa

Baldock P; Sainsbury A; Enriquez R; Couzens M; Herzog H; Gardiner EM, 2003, 'Gender dependent neuroregulation of bone mass: Evidence from theneuropeptide YY2/Y4 double knockout mouse', Journal of Bone and Mineral Research, 18, pp. S27 - S27

Sainsbury A; Schwarzer C; Couzens M; Herzog H, 2002, 'Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice', Diabetes, 51, pp. 3420 - 3427, http://dx.doi.org/10.2337/diabetes.51.12.3420

Herzog H, 2002, 'Hypothalamic Y2 receptors: Central coordination of energy homeostasis and bone mass regulation', Drug News and Perspectives, 15, pp. 506 - 510, http://dx.doi.org/10.1358/dnp.2002.15.8.740226

Blumenthal JB; Andersen RE; Mitchell BD; Seibert MJ; Yang H; Herzog H; Beamer BA; Franckowiak SC; Walston JD, 2002, 'Novel neuropeptide Y1 and Y5 receptor gene variants: Associations with serum triglyceride and high-density lipoprotein cholesterol levels', Clinical Genetics, 62, pp. 196 - 202, http://dx.doi.org/10.1034/j.1399-0004.2002.620302.x

Batterham RL; Cowley MA; Small CJ; Herzog H; Cohen MA; Dakin CL; Wren AM; Brynes AE; Low MJ; Ghatei MA; Cone RD; Bloom SR, 2002, 'Gut hormone PYY3-36 physiologically inhibits food intake', Nature, 418, pp. 650 - 654, http://dx.doi.org/10.1038/nature00887

Sainsbury A; Schwarzer C; Couzens M; Fetissov S; Furtinger S; Jenkins A; Cox HM; Sperk G; Hökfelt T; Herzog H, 2002, 'Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice', Proceedings of the National Academy of Sciences of the United States of America, 99, pp. 8938 - 8943, http://dx.doi.org/10.1073/pnas.132043299

Kopp J; Xu ZQ; Zhang X; Pedrazzini T; Herzog H; Kresse A; Wong H; Walsh JH; Hökfelt T, 2002, 'Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization', Neuroscience, 111, pp. 443 - 532, http://dx.doi.org/10.1016/S0306-4522(01)00463-8

Sainsbury A; Schwarzer C; Couzens M; Jenkins A; Oakes SR; Ormandy CJ; Herzog H, 2002, 'Y4 receptor knockout rescues fertility in ob/ob mice', Genes and Development, 16, pp. 1077 - 1088, http://dx.doi.org/10.1101/gad.979102

Hyland NP; Herzog H; Cox HM, 2002, 'Decreased sensitivity to pancreatic polypeptide in colonic mucosa from Y-2 receptor knockout mice', BRITISH JOURNAL OF PHARMACOLOGY, 135, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000174345200043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tough IR; De Souza RJ; Herzog H; Cox HM, 2002, 'Pancreatic polypeptide responses in colonic mucosal and smooth muscle preparations from wild type and Y-4 receptor knockout mice', BRITISH JOURNAL OF PHARMACOLOGY, 135, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000174345200044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sainsbury A; Cooney GJ; Herzog H, 2002, 'Hypothalamic regulation of energy homeostasis', Best Practice and Research Clinical Endocrinology and Metabolism, 16, pp. 623 - 637, http://dx.doi.org/10.1053/beem.2002.0230

Baldock PA; Sainsbury A; Couzens M; Enriquez RF; Thomas GP; Gardiner EM; Herzog H, 2002, 'Hypothalamic Y2 receptors regulate bone formation', Journal of Clinical Investigation, 109, pp. 915 - 921, http://dx.doi.org/10.1172/JCI0214588

Smith-White MA; Herzog H; Potter EK, 2002, 'Cardiac function in neuropeptide Y Y4 receptor-knockout mice', Regulatory Peptides, 110, pp. 47 - 54

Smith-White MA; Herzog H; Potter EK, 2002, 'Role of neuropeptide Y Y2 receptors in modulation of cardiac parasympathetic neurotransmission', Regulatory Peptides, 103, pp. 105 - 111

Sainsbury A; Couzens M; Lui M; Herzog H, 2001, 'A role of hypothalamic Upsilon 2 receptors in body weight regulation revealed by comparison of germline and Cre-mediated arcuate deletion', OBESITY RESEARCH, 9, pp. 56S - 56S, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000171076300017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Baldock PA; Thomas GP; Sainsbury A; Couzens M; Enriquez RF; Herzog H; Gardiner EM, 2001, 'Neuropeptide Y2 receptor has a role in bone homeostasis independent of body weight.', JOURNAL OF BONE AND MINERAL RESEARCH, 16, pp. S141 - S141, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000170709000018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Cox HM; Pollock EL; Tough IR; Herzog H, 2001, 'Multiple Y receptors mediate pancreatic polypeptide responses in mouse colon mucosa', Peptides, 22, pp. 445 - 452, http://dx.doi.org/10.1016/S0196-9781(01)00355-2

Sheng Y; Reddel SW; Herzog H; Wang YX; Brighton T; France MP; Krilis SA, 2001, 'Impaired In vitro thrombin generation in beta 2-glycoprotein I null mice', ARTHRITIS RESEARCH & THERAPY, 3, http://dx.doi.org/10.1186/ar248

Sainsbury A; Herzog H, 2001, 'Inhibitory effects of central neuropeptide Y on the somatotropic and gonadotropic axes in male rats are independent of adrenal hormones', Peptides, 22, pp. 467 - 471, http://dx.doi.org/10.1016/S0196-9781(01)00342-4

Goumain M; Voisin T; Lorinet AM; Ducroc R; Tsocas A; Rozé C; Rouet-Benzineb P; Herzog H; Balasubramaniam A; Laburthe M, 2001, 'The peptide YY-preferring receptor mediating inhibition of small intestinal secretion is a peripheral Y2 receptor: Pharmacological evidence and molecular cloning', Molecular Pharmacology, 60, pp. 124 - 134, http://dx.doi.org/10.1016/s0026-895x(24)23056-x

Sheng YH; Reddel SW; Herzog H; Brighton TA; France MP; Robertson SL; Krilis S; Wang YX, 2001, 'Impaired thrombin generation in Beta 2-gylcoprotein I null mice', The Journal of Biological Chemistry, pp. 13817 - 13821

Goumain M; Voisin T; Lorinet A-M; Ducroc R; Tsocas A; Rozé C; Rouet-Benzineb P; Herzog H; Balasubramaniam A; Laburthe M, 2001, 'The Peptide YY-Preferring Receptor Mediating Inhibition of Small Intestinal Secretion Is a Peripheral Y2 Receptor: Pharmacological Evidence and Molecular Cloning', Molecular Pharmacology, 60, pp. 124 - 134, http://dx.doi.org/10.1016/s0026-895x(24)23056-x

Dumont Y; Jacques D; St-Pierre JA; Tong Y; Parker R; Herzog H; Quirion R, 2000, 'Chapter IX Neuropeptide Y, peptide YY and pancreatic polypeptide receptor proteins and mRNAs in mammalian brains', Handbook of Chemical Neuroanatomy, 16, pp. 375 - 475, http://dx.doi.org/10.1016/S0924-8196(00)80011-1

Parker RMC; Copeland NG; Eyre HJ; Liu M; Gilbert DJ; Crawford J; Couzens M; Sutherland GR; Jenkins NA; Herzog H, 2000, 'Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family', Molecular Brain Research, 77, pp. 199 - 208, http://dx.doi.org/10.1016/S0169-328X(00)00052-8

Parker R; Liu M; Eyre HJ; Copeland NG; Gilbert DJ; Crawford J; Sutherland GR; Jenkins NA; Herzog H, 2000, 'Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6', Biochimica Et Biophysica Acta Gene Structure and Expression, 1491, pp. 369 - 375, http://dx.doi.org/10.1016/S0167-4781(00)00023-3

Couzens M; Liu M; Tüchler C; Kofler B; Nessler-Menardi C; Parker RMC; Klocker H; Herzog H, 2000, 'Peptide YY-2 (PYY2) and pancreatic polypeptide-2 (PPY2): Species- specific evolution of novel members of the neuropeptide Y gene family', Genomics, 64, pp. 318 - 323, http://dx.doi.org/10.1006/geno.2000.6132

McCrea K; Wisialowski T; Cabrele C; Church B; Beck-Sickinger A; Kraegen E; Herzog H, 2000, '2-36[K4,RYYSA19-23]PP a novel Y5-receptor preferring ligand with strong stimulatory effect on food intake', Regulatory Peptides, 87, pp. 47 - 58, http://dx.doi.org/10.1016/S0167-0115(99)00108-1

Wisialowski T; Parker R; Preston E; Sainsbury A; Kraegen E; Herzog H; Cooney G, 2000, 'Adrenalectomy reduces neuropeptide Y-induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus', Journal of Clinical Investigation, 105, pp. 1253 - 1259, http://dx.doi.org/10.1172/JCI8695

Herzog H, 2000, 'Human Y1/Y5 receptor gene cluster. Isolation and characterization.', Methods in Molecular Biology Clifton N J, 153, pp. 13 - 24, http://dx.doi.org/10.1385/1-59259-042-x:13

Parker R; Herzog H, 2000, 'Localization of Y-receptor subtype mRNAs in rat brain by digoxigenin labeled in situ hybridization.', Methods in Molecular Biology Clifton N J, 153, pp. 165 - 183, http://dx.doi.org/10.1385/1-59259-042-x:165

Jenkinson CP; Cray K; Walder K; Herzog H; Hanson R; Ravussin E, 2000, 'Novel polymorphisms in the neuropeptide-Y Y5 receptor associated with obesity in Pima Indians', International Journal of Obesity, 24, pp. 580 - 584, http://dx.doi.org/10.1038/sj.ijo.0801200

McCrea KE; Herzog H, 2000, 'Radioligand binding studies. Pharmacological profiles of cloned Y-receptor subtypes.', Methods in Molecular Biology Clifton N J, 153, pp. 231 - 239, http://dx.doi.org/10.1385/1-59259-042-x:231

Nichol KA; Morey A; Couzens MH; Shine J; Herzog H; Cunningham AM, 1999, 'Conservation of expression of neuropeptide Y5 receptor between human and rat hypothalamus and limbic regions suggests an integral role in central neuroendocrine control', Journal of Neuroscience, 19, pp. 10295 - 10304, http://dx.doi.org/10.1523/jneurosci.19-23-10295.1999

Herzog H, 1999, 'Regional distribution of Y-receptor subtype mRNAs in rat brain', European Journal of Neuroscience, 11, pp. 1431 - 1448, http://dx.doi.org/10.1046/j.1460-9568.1999.00553.x

Liu M; Parker RMC; Darby K; Eyre HJ; Copeland NG; Crawford J; Gilbert DJ; Sutherland GR; Jenkins NA; Herzog H, 1999, 'GPR56, a novel secretin-like human G-protein-coupled receptor gene', Genomics, 55, pp. 296 - 305, http://dx.doi.org/10.1006/geno.1998.5644

St-Pierre JA; Dumont Y; Nouel D; Herzog H; Hamel E; Quirion R, 1998, 'Preferential expression of the neuropeptide Y Y1 over the Y2 receptor subtype in cultured hippocampal neurones and cloning of the rat Y2 receptor', British Journal of Pharmacology, 123, pp. 183 - 194, http://dx.doi.org/10.1038/sj.bjp.0701589

Parker RL; Herzog H, 1998, 'Comparison of Y receptor sub-type expression in the rat hippocampus', Regulatory Peptides, pp. 109 - 115

Michel MC; Beck-Sickinger A; Cox H; Doods HN; Herzog H; Larhammer D; Quirion R; Schwartz T; Westfall T, 1998, 'XVI International Union of Pharmacology Recommendations for the nomenclature of neuropeptide Y, Peptide YY and Pancreatic Polypeptide Receptors', Pharmacological Reviews, pp. 143 - 150

Darby K; Eyre HJ; Lapsys N; Copeland NG; Gilbert DJ; Couzens M; Antonova O; Sutherland GR; Jenkins NA; Herzog H, 1997, 'Assignment of the Y4 receptor gene (PPYR1) to human chromosome 10q11.2 and mouse chromosome 14', Genomics, 46, pp. 513 - 515, http://dx.doi.org/10.1006/geno.1997.5071

Sperk G; Herzog H, 1997, 'Anticonvulsant action of neuropeptide Y', Nature Medicine, 3, pp. 728 - 729, http://dx.doi.org/10.1038/nm0797-728

Blomqvist AG; Herzog H, 1997, 'Y-receptor subtypes - How many more?', Trends in Neurosciences, 20, pp. 294 - 298, http://dx.doi.org/10.1016/S0166-2236(96)01057-0

Sheng YH; Herzog H; Krilis S, 1997, 'Cloning and characterization of the gene encoding mouse B2-Glycoprotein 1', Genomics, pp. 128 - 130

Herzog H; Darby K; Ball H; Hort J; Beck-Sickinger A; Shine J, 1997, 'Overlapping gene structure of the human neuropeptide Y receptor suBtypes Y1 and Y 5 suggests co-ordinate transcriptional regulation', Genomics, pp. 315 - 319

Herzog H; Darby K; Ball H; Hort J; Beck-Sickinger A; Shine J, 1997, 'OVERLAPPING GENE STRUCTURE OF THE HUMAN NEUROPEPTIDE Y RECEPTOR SUBTYPES Y1 AND Y5 SUGGESTS CO-ORDINATE TRANSCRIPTIONAL REGULATION', Genomics, pp. 315 - 319

Lapsys NM; Furler SM; Moore KJ; Nguyen TM; Herzog H; Howard GM; Samaras K; Carey DJ; Morrison NA; Eisman JA; Chisholm DJ, 1997, 'Relationship of a novel polymorphic marker near the human oBese (oB) gene to fat mass in healthy women (short communication).', Obesity Research, pp. 430 - 433

Sautel M; Rudolf K; Wittneben H; Herzog H; Martinez R; Munoz M; Eberlein W; Engel W; Walker P; Beck-Sickinger AG, 1996, 'Neuropeptide Y and the nonpeptide antagonist BIBP 3226 share an overlapping binding site at the human Y1 receptor', Molecular Pharmacology, 50, pp. 285 - 292, http://dx.doi.org/10.1016/s0026-895x(25)09222-3

Herzog H; Darby K; Hort J; Shine J, 1996, 'Intron 17 of the human retinoblastoma susceptibility gene encodes an actively transcribed G protein-couled receptor gene', Genome Research, pp. 858 - 861

Munch G; Walker P; Shine J; Herzog H, 1996, 'Ligand binding analysis of human neuropeptides Y1 receptor mutants exposed in E-Coli', Receptors and Channels, pp. 291 - 297

Herzog H; Nicholl J; Hort J; Sutherland GR; Shine J, 1996, 'Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase to 8p11.2-22 by non isotopic in situhybridisation', Genomics, pp. 484 - 486

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