By Professor Herbert Herzog

Journal articles

Lee K; Chan JY; Liang C; Ip CK; Shi YC; Herzog H; Hughes WE; Bensellam M; Delghingaro-Augusto V; Koina ME; Nolan CJ; Laybutt DR, 2022, 'XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice', Diabetologia, 65, pp. 984 - 996, http://dx.doi.org/10.1007/s00125-022-05669-7

Qi Y; Lee NJ; Ip CK; Enriquez R; Tasan R; Zhang L; Herzog H, 2022, 'NPY derived from AGRP neurons controls feeding via Y1 and energy expenditure and food foraging behaviour via Y2 signalling', Molecular Metabolism, 59, http://dx.doi.org/10.1016/j.molmet.2022.101455

Mitchell CS; Goodman EK; Tedesco CR; Nguyen K; Zhang L; Herzog H; Begg DP, 2022, 'The Effect of Dietary Fat and Sucrose on Cognitive Functioning in Mice Lacking Insulin Signaling in Neuropeptide Y Neurons', Frontiers in Physiology, 13, http://dx.doi.org/10.3389/fphys.2022.841935

Langley DB; Schofield P; Jackson J; Herzog H; Christ D, 2022, 'Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY)', Neuropeptides, 92, http://dx.doi.org/10.1016/j.npep.2022.102231

Rezitis J; Herzog H; Ip CK, 2022, 'Neuropeptide Y interaction with dopaminergic and serotonergic pathways: interlinked neurocircuits modulating hedonic eating behaviours', Progress in Neuro Psychopharmacology and Biological Psychiatry, 113, http://dx.doi.org/10.1016/j.pnpbp.2021.110449

Yang CH; Ann-Onda D; Lin X; Fynch S; Nadarajah S; Pappas EG; Liu X; Scott JW; Oakhill JS; Galic S; Shi Y; Moreno-Asso A; Smith C; Loudovaris T; Levinger I; Eizirik DL; Laybutt DR; Herzog H; Thomas HE; Loh K, 2022, 'Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes', Molecular Metabolism, 55, http://dx.doi.org/10.1016/j.molmet.2021.101413

Goodman EK; Mitchell CS; Teo JD; Gladding JM; Abbott KN; Rafiei N; Zhang L; Herzog H; Begg DP, 2022, 'The effect of insulin receptor deletion in neuropeptide Y neurons on hippocampal dependent cognitive function in aging mice', Journal of Integrative Neuroscience, 21, http://dx.doi.org/10.31083/j.jin2101006

Yan C; Zeng T; Lee K; Nobis M; Loh K; Gou L; Xia Z; Gao Z; Bensellam M; Hughes W; Lau J; Zhang L; Ip CK; Enriquez R; Gao H; Wang QP; Wu Q; Haigh JJ; Laybutt DR; Timpson P; Herzog H; Shi YC, 2021, 'Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-22925-3

Koller J; Herzog H; Zhang L, 2021, 'The distribution of Neuropeptide FF and Neuropeptide VF in central and peripheral tissues and their role in energy homeostasis control', Neuropeptides, 90, http://dx.doi.org/10.1016/j.npep.2021.102198

Zhang L; Koller J; Ip CK; Gopalasingam G; Bajaj N; Lee NJ; Enriquez RF; Herzog H, 2021, 'Lack of neuropeptide FF signalling in mice leads to reduced repetitive behavior, altered drinking behavior, and fuel type selection', FASEB Journal, 35, http://dx.doi.org/10.1096/fj.202100703R

Malone IG; Hunter BK; Rossow HL; Herzog H; Zolotukhin S; Munger SD; Dotson CD, 2021, 'Y1 receptors modulate taste-related behavioral responsiveness in male mice to prototypical gustatory stimuli', Hormones and Behavior, 136, http://dx.doi.org/10.1016/j.yhbeh.2021.105056

Kakall ZM; Gopalasingam G; Herzog H; Zhang L, 2021, 'Dynamic regional alterations in mouse brain neuronal activity following short-term changes in energy balance', Obesity, 29, pp. 1650 - 1663, http://dx.doi.org/10.1002/oby.23253

Zhang L; Gopalasingam G; Herzog H, 2021, 'Ninjin'yoeito, a herbal medicine, enhances glucose tolerance in mice', Neuropeptides, 88, http://dx.doi.org/10.1016/j.npep.2021.102150

Bittencourt JC; Diniz GB; Lovejoy DA; Herzog H, 2021, 'Editorial: The Phylogenetic History of Hypothalamic Neuromodulators', Frontiers in Neuroscience, 15, http://dx.doi.org/10.3389/fnins.2021.712448

Zhang L; Clark T; Gopalasingam G; Neely GG; Herzog H, 2021, 'Ninjin'yoeito modulates feeding and activity under negative energy balance conditions via the NPY system', Neuropeptides, 87, http://dx.doi.org/10.1016/j.npep.2021.102149

Enriquez RF; Lee NJ; Herzog H, 2021, 'AgRP signalling negatively regulates bone mass', Journal of Neuroendocrinology, 33, http://dx.doi.org/10.1111/jne.12978

Lee NJ; Herzog H, 2021, 'Coordinated regulation of energy and glucose homeostasis by insulin and the NPY system', Journal of Neuroendocrinology, 33, http://dx.doi.org/10.1111/jne.12925

Farzi A; Ip CK; Reed F; Enriquez R; Zenz G; Durdevic M; Zhang L; Holzer P; Herzog H, 2021, 'Lack of peptide YY signaling in mice disturbs gut microbiome composition in response to high-fat diet', FASEB Journal, 35, http://dx.doi.org/10.1096/fj.202002215R

Wee NKY; Nguyen AD; Enriquez RF; Zhang L; Herzog H; Baldock PA, 2020, 'Neuropeptide Y Regulation of Energy Partitioning and Bone Mass During Cold Exposure', Calcified Tissue International, 107, pp. 510 - 523, http://dx.doi.org/10.1007/s00223-020-00745-9

Chen J; Cheng M; Wang L; Zhang L; Xu D; Cao P; Wang F; Herzog H; Song S; Zhan C, 2020, 'A Vagal-NTS Neural Pathway that Stimulates Feeding', Current Biology, 30, pp. 3986 - 3998.e5, http://dx.doi.org/10.1016/j.cub.2020.07.084

Lee NJ; Qi Y; Enriquez RF; Clarke I; Ip CK; Wee N; Baldock PA; Herzog H, 2020, 'Energy partitioning between fat and bone mass is controlled via a hypothalamic leptin/NPY relay', International Journal of Obesity, 44, pp. 2149 - 2164, http://dx.doi.org/10.1038/s41366-020-0550-6

Zhang L; Reed F; Herzog H, 2020, 'Leptin signalling on arcuate NPY neurones controls adiposity independent of energy balance or diet composition', Journal of Neuroendocrinology, 32, http://dx.doi.org/10.1111/jne.12898

Alonso AM; Cork SC; Ma Y; Arnold M; Herzog H; Bloom SR; Distaso W; Murphy KG; Salem V, 2020, 'SAT-607 The Vagus Nerve and the Hypothalamus Mediate Different Aspects of the Anorectic Effects of PYY3-36', Journal of the Endocrine Society, 4, http://dx.doi.org/10.1210/jendso/bvaa046.1337

Wang QP; Lin YQ; Lai ML; Su Z; Oyston LJ; Clark T; Park SJ; Khuong TM; Lau MT; Shenton V; Shi YC; James DE; Ja WW; Herzog H; Simpson SJ; Neely GG, 2020, 'PGC1α Controls Sucrose Taste Sensitization in Drosophila', Cell Reports, 31, http://dx.doi.org/10.1016/j.celrep.2020.03.044

Lee NJ; Qi Y; Enriquez RF; Ip CK; Herzog H, 2020, 'Lack of NPY in neurotensin neurons leads to a lean phenotype', Neuropeptides, 80, http://dx.doi.org/10.1016/j.npep.2019.101994

Sousa DM; Martins PS; Leitão L; Alves CJ; Gomez-Lazaro M; Neto E; Conceição F; Herzog H; Lamghari M, 2020, 'The lack of neuropeptide Y-Y1 receptor signaling modulates the chemical and mechanical properties of bone matrix', FASEB Journal, 34, pp. 4163 - 4177, http://dx.doi.org/10.1096/fj.201902796R

Herzog H, 2020, 'Integrated pathways that control stress and energy homeostasis', Nature Reviews Endocrinology, 16, pp. 75 - 76, http://dx.doi.org/10.1038/s41574-019-0298-z

Alonso AM; Cork SC; Ma Y; Herzog H; Bloom SR; Distaso W; Murphy KG; Salem V, 2019, 'Investigating the role of vagal Y2R in PYY_3-36-mediated appetite suppression', Endocrine Abstracts, http://dx.doi.org/10.1530/endoabs.65.oc2.4

Beck-Sickinger A; Colmers WF; Cox HM; Doods HN; Herzog H; Larhammar D; Michel MC; Quirion R; Schwartz T; Westfall T, 2019, 'Neuropeptide Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database', IUPHAR/BPS Guide to Pharmacology CITE, 2019, http://dx.doi.org/10.2218/gtopdb/f46/2019.4

Ip CK; Zhang L; Farzi A; Qi Y; Clarke I; Reed F; Shi YC; Enriquez R; Dayas C; Graham B; Begg D; Brüning JC; Lee NJ; Hernandez-Sanchez D; Gopalasingam G; Koller J; Tasan R; Sperk G; Herzog H, 2019, 'Amygdala NPY Circuits Promote the Development of Accelerated Obesity under Chronic Stress Conditions', Cell Metabolism, 30, pp. 111 - 128.e6, http://dx.doi.org/10.1016/j.cmet.2019.04.001

Zhang L; Hernandez-Sanchez D; Herzog H, 2019, 'Regulation of feeding-related behaviors by arcuate neuropeptide Y neurons', Endocrinology, 160, pp. 1411 - 1420, http://dx.doi.org/10.1210/en.2019-00056

Fujiwara S; Hoshizaki M; Ichida Y; Lex D; Kuroda E; Ishii KJ; Magi S; Okada M; Takao H; Gandou M; Imai H; Hara R; Herzog H; Yoshimura A; Okamura H; Penninger JM; Slutsky AS; Uhlig S; Kuba K; Imai Y, 2019, 'Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection', Nature Microbiology, 4, pp. 258 - 268, http://dx.doi.org/10.1038/s41564-018-0289-1

Lee NJ; Clarke IM; Zengin A; Enriquez RF; Nagy V; Penninger JM; Baldock PA; Herzog H, 2019, 'RANK deletion in neuropeptide Y neurones attenuates oestrogen deficiency-related bone loss', Journal of Neuroendocrinology, 31, http://dx.doi.org/10.1111/jne.12687

Ip CK; Herzog H; Zhang L, 2019, 'Chronic stress and energy homoeostasis', Aging, 11, pp. 9963 - 9964, http://dx.doi.org/10.18632/aging.102500

Comeras LB; Herzog H; Tasan RO, 2019, 'Neuropeptides at the crossroad of fear and hunger: a special focus on neuropeptide Y', Annals of the New York Academy of Sciences, http://dx.doi.org/10.1111/nyas.14179

Ip CKK; Zhang L; Farzi A; Clarke I; Reed F; Shi Y-C; Enriquez R; Qi Y; Tasan R; Sperk G; Herzog H, 2019, 'Coordinated activation of central amygdala–arcuate nucleus NPY circuits are required for the development of stress-induced obesity', Obesity Research & Clinical Practice, 13, pp. 284 - 284, http://dx.doi.org/10.1016/j.orcp.2018.11.141

Yue Q; Lee N; Zhang L; Enriquez R; Herzog H, 2019, 'Distinct populations of Arc NPY neurons control specific aspects of energy homeostasis', Obesity Research & Clinical Practice, 13, pp. 277 - 277, http://dx.doi.org/10.1016/j.orcp.2018.11.123

Lee NJ; Ali N; Zhang L; Qi Y; Clarke I; Enriquez RF; Brzozowska M; Lee IC; Rogers MJ; Laybutt DR; Center JR; Baldock PA; Herzog H, 2019, 'Osteoglycin, a novel coordinator of bone and glucose homeostasis', Obesity Research & Clinical Practice, 13, pp. 256, http://dx.doi.org/10.1016/j.orcp.2018.11.063

Shi Y-C; Loh K; Lee K; Herzog H, 2019, 'Peripheral NPY antagonism reduces HFD-induced adiposity and improves glucose tolerance in ageing mice', Obesity Research & Clinical Practice, 13, pp. 293 - 294, http://dx.doi.org/10.1016/j.orcp.2018.11.167

Herzog H, 2019, 'Role of amygdala NPY in the development of stress-induced obesity', Obesity Research & Clinical Practice, 13, pp. 256 - 256, http://dx.doi.org/10.1016/j.orcp.2018.11.060

Zhang L; Ip CK; Lee ICJ; Qi Y; Reed F; Karl T; Low JK; Enriquez RF; Lee NJ; Baldock PA; Herzog H, 2018, 'Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-06462-0

Hörmer BA; Verma D; Gasser E; Wieselthaler-Hölzl A; Herzog H; Tasan RO, 2018, 'Hippocampal NPY Y2 receptors modulate memory depending on emotional valence and time', Neuropharmacology, 143, pp. 20 - 28, http://dx.doi.org/10.1016/j.neuropharm.2018.09.018

Loh K; Shi YC; Bensellam M; Lee K; Laybutt DR; Herzog H, 2018, 'Y1 receptor deficiency in β-cells leads to increased adiposity and impaired glucose metabolism', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-30140-2

Wee NKY; Enriquez RF; Nguyen AD; Horsnell H; Kulkarni R; Khor EC; Herzog H; Baldock PA, 2018, 'Diet-induced obesity suppresses cortical bone accrual by a neuropeptide Y-dependent mechanism', International Journal of Obesity, 42, pp. 1925 - 1938, http://dx.doi.org/10.1038/s41366-018-0028-y

Farzi A; Lau J; Ip CK; Qi Y; Shi YC; Zhang L; Tasan R; Sperk G; Herzog H, 2018, 'Arcuate nucleus and lateral hypothalamic cart neurons in the mouse brain exert opposing effects on energy expenditure', Elife, 7, http://dx.doi.org/10.7554/eLife.36494

Farzi A; Lau J; Ip CK; Qi Y; Shi Y-C; Zhang L; Tasan R; Sperk G; Herzog H, 2018, 'Author response: Arcuate nucleus and lateral hypothalamic CART neurons in the mouse brain exert opposing effects on energy expenditure', , http://dx.doi.org/10.7554/elife.36494.021

Wang QP; Browman D; Herzog H; Gregory Neely G, 2018, 'Non-nutritive sweeteners possess a bacteriostatic effect and alter gut microbiota in mice', Plos One, 13, http://dx.doi.org/10.1371/journal.pone.0199080

Lee NJ; Ali N; Qi J; Clarke RF; Enriquez RF; Brzozowska M; Lee IC; Rogers MJ; Laybutt DR; Center JR; Baldock PA; Herzog H, 2018, 'Osteoglycin, an Osteoblast-derived Regulator of Bone Mass and Glucose Homeostasis', Molecular Metabolism, http://dx.doi.org/10.1016/j.molmet.2018.05.004

Tough IR; Forbes S; Herzog H; Jones RM; Schwartz TW; Cox HM, 2018, 'Bidirectional GPR119 Agonism Requires Peptide YY and Glucose for Activity in Mouse and Human Colon Mucosa', Endocrinology, 159, pp. 1704 - 1717, http://dx.doi.org/10.1210/en.2017-03172

Lee NJ; Clarke IM; Enriquez RF; Nagy V; Penninger J; Baldock PA; Herzog H, 2018, 'Central RANK signalling in NPY neurons alters bone mass in male mice', Neuropeptides, 68, pp. 75 - 83, http://dx.doi.org/10.1016/j.npep.2018.02.004

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