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Preprints

Thoms JAI; Yan F; Hampton HR; Davidson S; Joshi S; Saw J; Sarowar CH; Lim XY; Nunez AC; Kakadia PM; Bhuyan GS; Zou X; Nguyen M; Ghodousi ES; Koch FC; Vafaee F; Pickford R; Raftery MJ; Hough S; Buckland G; Bailey M; Ghodke Y; Absar N; Vaughan L; Pasalic L; Fong CY; Kenealy M; Hiwase DK; Stoddart RI; Mohammed S; Lee L; Passam FH; Larsen SR; Spring KJ; Skarratt KK; Rebeiro P; Presgrave P; Stevenson WS; Ling S; Tiley C; Fuller SJ; Roncolato F; Enjeti AK; Hoenemann D; Lemech C; Jolly CJ; Bohlander SK; Curtis DJ; Wong JWH; Unnikrishnan A; Hertzberg M; Olivier J; Polizzotto MN; Pimanda JE, Clinical Response to Azacitidine in Myelodysplastic Neoplasms is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor cells in vivo, http://dx.doi.org/10.1101/2024.07.19.24310679

Srivastava P; Romanazzo S; Ireland J; Nemec S; Molley TG; Jayathilaka P; Pandzic E; Yeola A; Chandrakanthan V; Pimanda J; Kilian K, Defined microenvironments trigger in vitro gastrulation in human pluripotent stem cells, http://dx.doi.org/10.1101/2021.10.28.466327

Liu Y-C; Fabiani E; Kwon J; Gao C; Falconi G; Valentini L; Gurnari C; Liu YV; Jones AI; Yang J; Yang H; Thoms JAI; Unnikrishnan A; Pimanda JE; Pan R; Voso MT; Tenen DG; Chai L, Demethylation and upregulation of an oncogene post hypomethylating treatment, http://dx.doi.org/10.1101/2020.07.21.20157776

Thoms JAI; Knezevic K; Harvey G; Huang Y; Seneviratne JA; Carter DR; Subramanian S; Skhinas J; Chacon D; Shah A; de Jong I; Beck D; Göttgens B; Larsson J; Wong JWH; Zanini F; Pimanda JE, Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells, http://dx.doi.org/10.1101/2020.10.26.353797

Tan S; Joseph C; Sobah ML; Chalk AM; Schleibs K; Lee SC; Tjin G; Chugh S; Mo X; Grace CS; Truong JQ; Smeets MF; Rice KL; Parker MW; Unnikrishnan A; Kulasekararaj AG; Mufti GJ; Tobiasson M; Hellstrom-Lindberg E; Pimanda JE; Gudas LJ; McCarthy DJ; Holien JK; Walkley CR; Wall M; Purton LE, Dysregulated expression of Hoxa1 isoforms in hematopoietic stem and progenitor cells causes myelodysplastic syndromes, http://dx.doi.org/10.1101/2023.04.24.538176

Truong P; Shen S; Joshi S; Islam I; Zhong L; Raftery MJ; Afrasiabi A; Alinejad-Rokny H; Nguyen M; Zou X; Bhuyan GS; Sarowar CH; Ghodousi ES; Stonehouse O; Mohamed S; Toscan CE; Connerty P; Kakadia PM; Bohlander SK; Michie KA; Larsson J; Lock RB; Walkley CR; Thoms JAI; Jolly CJ; Pimanda JE, Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and SUMOylation Blockade in MDS/AML, http://dx.doi.org/10.1101/2024.04.17.589858

Poulos RC; Perera D; Packham D; Shah A; Janitz C; Pimanda JE; Hawkins N; Ward RL; Hesson LB; Wong JW, In search of non-coding driver mutations by deep sequencing of regulatory elements in colorectal cancer, http://dx.doi.org/10.1101/249300

Yang J; Gao C; Liu M; Chen Z; Liu Y-C; Kwon J; Qi J; Tian X; Stein A; Liu Y; Kong NR; Wu Y; Yin S; Xi JJ; Luo H; Silberstein LE; Thoms JAI; Unnikrishnan A; Pimanda JE; Tenen DG; Chai L, Induction of a SALL4-dependency for targeted cancer therapy, http://dx.doi.org/10.1101/2020.07.10.197434

Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Hung T; Power C; Hardy P; D. D; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE, Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine, http://dx.doi.org/10.1101/2020.06.04.130872

Tavassoli H; Rorimpandey P; Kang YC; Carnell M; Brownlee C; Pimanda JE; Chan PPY; Chandrakanthan V, Label-free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes Using Inertial Microfluidics, http://dx.doi.org/10.1101/2020.08.31.243592

Chandrakanthan V; Rorimpandey P; Zanini F; Chacon D; Kang YC; Knezevic K; Huang Y; Qiao Q; Oliver RA; Unnikrishnan A; Carter DR; Lee B; Brownlee C; Power C; Mendez-Ferrer S; Enikolopov G; Walsh W; Göttgens B; Taoudi S; Beck D; Pimanda JE, Mesoderm-Derived PDGFRA+ Cells Regulate the Emergence of Hematopoietic Stem Cells in the Dorsal Aorta, http://dx.doi.org/10.1101/2021.08.08.455592

Anande G; Deshpande NP; Mareschal S; Batcha AMN; Hampton HR; Herold T; Lehmann S; Wilkins MR; Wong JWH; Unnikrishnan A; Pimanda JE, RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML, http://dx.doi.org/10.1101/2020.01.10.895714


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