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Journal articles
, 2026, 'Genomic Evolution of Myeloproliferative Neoplasms and Therapy-Associated Mutagenesis', Cancer Discovery, 16, pp. 1843 - 1858, http://dx.doi.org/10.1158/2159-8290.CD-26-0410
, 2026, 'PU.1 inflames lower-risk MDS', Blood, 147, pp. 2283 - 2285, http://dx.doi.org/10.1182/blood.2026033252
, 2025, 'MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia', Blood, 146, pp. 3098 - 3105, http://dx.doi.org/10.1182/blood.2025028914
, 2025, 'Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs', Nature Communications, 16, http://dx.doi.org/10.1038/s41467-025-59796-x
, 2025, 'Variability in interventional trials in clonal haematopoiesis', Blood, 146, pp. 6696, http://dx.doi.org/10.1182/blood-2025-6696
, 2025, 'Is online pathology education an effective and equitable approach for medical students?', Educacion Medica, 26, http://dx.doi.org/10.1016/j.edumed.2025.101065
, 2025, '3237 – LONGITUDINAL SINGLE-CELL PROFILING OF MDS STEM/PROGENITOR CELLS REVEALS FEATURES OF AZACITIDINE RESPONSE AND RESISTANCE', Experimental Hematology, 151, pp. 105231, http://dx.doi.org/10.1016/j.exphem.2025.105231
, 2024, 'TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells', Nature Communications, 15, pp. 7360, http://dx.doi.org/10.1038/s41467-024-51646-6
, 2024, 'Clinical Response to Azacitidine in Myelodysplastic Neoplasms Is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor Cells In Vivo', Blood, 144, pp. 3223 - 3223, http://dx.doi.org/10.1182/blood-2024-201216
, 2024, 'Seeing MDS through the lens of genomics', Blood, 144, pp. 1552 - 1554, http://dx.doi.org/10.1182/blood.2024025676
, 2024, 'BloodChIP Xtra: an expanded database of comparative genome-wide transcription factor binding and gene-expression profiles in healthy human stem/progenitor subsets and leukemic cells', Nucleic Acids Research, 52, pp. D1131 - D1137, http://dx.doi.org/10.1093/nar/gkad918
, 2024, '3178 – LONGITUDINAL DRUG INCORPORATION, CLONAL COMPOSITION, AND DNA METHYLATION DYNAMICS IN MDS/CMML PATIENTS TREATED WITH AZA', Experimental Hematology, 137, pp. 104498, http://dx.doi.org/10.1016/j.exphem.2024.104498
, 2023, 'The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41067-2
, 2023, 'Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs', Blood, 142, pp. 1448 - 1462, http://dx.doi.org/10.1182/blood.2023021120
, 2023, 'Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia', Science translational medicine, 15, pp. eabm1262 - eabm1262, http://dx.doi.org/10.1126/scitranslmed.abm1262
, 2023, 'Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy', Blood, 141, pp. 1316 - 1321, http://dx.doi.org/10.1182/blood.2022018602
, 2023, 'Defined Microenvironments Trigger In Vitro Gastrulation in Human Pluripotent Stem Cells', Advanced Science, 10, http://dx.doi.org/10.1002/advs.202203614
, 2023, 'DDX41: the poster child for familial MDS/AML grows up', Blood, 141, pp. 447 - 449, http://dx.doi.org/10.1182/blood.2022018787
, 2022, 'Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and Mature Blood Cells from MDS/CMML Patients Pre- and Post-AZA Treatment', Blood, 140, pp. 9751 - 9752, http://dx.doi.org/10.1182/blood-2022-163158
, 2022, 'Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions', Blood, 140, pp. 2846 - 2848, http://dx.doi.org/10.1182/blood-2022-165620
, 2022, 'In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial', Blood, 140, pp. 6927 - 6929, http://dx.doi.org/10.1182/blood-2022-157634
, 2022, 'Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies', Leukemia, 36, pp. 2734 - 2738, http://dx.doi.org/10.1038/s41375-022-01705-y
, 2022, 'AML-131 ERG: From a Fortuitous Discovery to Potential Treatment for AML', Clinical Lymphoma Myeloma and Leukemia, 22, pp. S215 - S216, http://dx.doi.org/10.1016/S2152-2650(22)01225-3
, 2022, 'p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion', Blood, 140, pp. 464 - 477, http://dx.doi.org/10.1182/blood.2021014853
, 2022, 'Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aorta', Nature Cell Biology, 24, pp. 1211 - 1225, http://dx.doi.org/10.1038/s41556-022-00955-3
, 2022, 'P417: A SINGLE AMINO ACID AT THE PNT DOMAIN OF ERG MEDIATES ITS LEUKEMOGENIC ACTIVITY THROUGH INTERACTION WITH THE NCOR-HDAC3 CO-REPRESSOR COMPLEX.', HemaSphere, 6, pp. 317 - 318, http://dx.doi.org/10.1097/01.hs9.0000844556.94296.43
, 2022, 'P748: SINGLE CELL GENOTYPING OF MATCHED BONE MARROW AND PERIPHERAL BLOOD CELLS IN TREATMENT NAIVE AND AZA-TREATED MDS AND CMML', HemaSphere, 6, pp. 643 - 644, http://dx.doi.org/10.1097/01.hs9.0000845876.01682.15
, 2022, 'Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy', New England Journal of Medicine, 386, pp. 1998 - 2010, http://dx.doi.org/10.1056/NEJMoa2119771
, 2022, 'Analysing high-throughput sequencing data in Python with HTSeq 2.0', Bioinformatics, 38, pp. 2943 - 2945, http://dx.doi.org/10.1093/bioinformatics/btac166
, 2022, 'Analysing high-throughput sequencing data in Python with HTSeq 2.0.', Bioinformatics, 38, pp. 2943 - 2945, http://dx.doi.org/10.1093/bioinformatics/btac166
, 2022, 'Poster: AML-131 ERG: From a Fortuitous Discovery to Potential Treatment for AML', Clinical Lymphoma Myeloma and Leukemia, 22, pp. S129 - S129, http://dx.doi.org/10.1016/s2152-2650(22)00769-8
, 2021, 'Targeting an Inducible SALL4-Mediated Cancer Vulnerability with Sequential Therapy', Cancer Research, 81, pp. 6018 - 6028, http://dx.doi.org/10.1158/0008-5472.CAN-21-0030
, 2021, 'Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells', Blood, 138, pp. 1441 - 1455, http://dx.doi.org/10.1182/blood.2020009707
, 2021, 'To switch or not to switch: PU.1 expression is the question', Blood, 138, pp. 1289 - 1291, http://dx.doi.org/10.1182/blood.2021012112
, 2021, 'Label-Free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes Using Inertial Microfluidics', Small, 17, http://dx.doi.org/10.1002/smll.202006176
, 2021, '3034 – DISRUPTION OF A GATA2, TAL1, ERG REGULATORY CIRCUIT PROMOTES ERYTHROID TRANSITION IN HEALTHY AND LEUKEMIC STEM CELLS', Experimental Hematology, 100, pp. S59 - S59, http://dx.doi.org/10.1016/j.exphem.2021.12.255
, 2021, 'Heart on A Chip: Label‐Free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes Using Inertial Microfluidics (Small 8/2021)', Small, 17, http://dx.doi.org/10.1002/smll.202170034
, 2021, 'Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine', Science Advances, 7, pp. 2020.06.04.130872 - 2020.06.04.130872, http://dx.doi.org/10.1126/sciadv.abd1929
, 2020, 'Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers', Nature Communications, 11, pp. 5660, http://dx.doi.org/10.1038/s41467-020-19464-8
, 2020, 'The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1', Blood, 136, pp. 957 - 973, http://dx.doi.org/10.1182/blood.2019002548
, 2020, 'Titans awake: HMAs for virus-driven ATL', Blood, 136, pp. 777 - 779, http://dx.doi.org/10.1182/blood.2020006488
, 2020, 'RNA Splicing Alterations Induce a Cellular Stress Response Associated with Poor Prognosis in Acute Myeloid Leukemia.', Clin Cancer Res, 26, pp. 3597 - 3607, http://dx.doi.org/10.1158/1078-0432.CCR-20-0184
, 2020, 'DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts', Haematologica, 105, pp. 1517 - 1526, http://dx.doi.org/10.3324/haematol.2018.215699
, 2020, 'Constitutive CHK1 Expression Drives a pSTAT3–CIP2A Circuit that Promotes Glioblastoma Cell Survival and Growth', Molecular Cancer Research, 18, pp. 709 - 722, http://dx.doi.org/10.1158/1541-7786.MCR-19-0934
, 2020, 'Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers with low mutational burden', The Journal of Immunology, 204, pp. 242.14 - 242.14, http://dx.doi.org/10.4049/jimmunol.204.supp.242.14
, 2020, 'Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys', Plos Pathogens, 16, pp. e1008262, http://dx.doi.org/10.1371/journal.ppat.1008262
, 2019, 'A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia', Cancer Cell, 36, pp. 660 - 673.e11, http://dx.doi.org/10.1016/j.ccell.2019.11.001
, 2019, 'Transcriptional networks in acute myeloid leukemia', Genes Chromosomes and Cancer, 58, pp. 859 - 874, http://dx.doi.org/10.1002/gcc.22794
, 2019, 'Shared roles for Scl and Lyl1 in murine platelet production and function', Blood, 134, pp. 826 - 835, http://dx.doi.org/10.1182/blood.2019896175
, 2019, 'Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing', JNCI Cancer Spectrum, 3, pp. pkz012, http://dx.doi.org/10.1093/jncics/pkz012