By Professor Mark Parsons

Journal articles

Campbell BC; Christensen S; Yassi N; Sharma G; Bivard A; Lin L; Levi CR; Desmond PM; Donnan GA; Straka M; Lansberg MG; Bammer R; Albers GW; Davis SM; Parsons MW, 2013, 'Abstract WP45: Comparison of Automated Whole Brain CT Perfusion Analysis with Perfusion-Diffusion MRI in Ischemic Stroke', Stroke, 44, http://dx.doi.org/10.1161/str.44.suppl_1.awp45

Lin L; Bivard A; Parsons MW, 2013, 'Perfusion patterns of ischemic stroke on computed tomography perfusion.', J Stroke, 15, pp. 164 - 173, http://dx.doi.org/10.5853/jos.2013.15.3.164

Carey LM; Crewther S; Salvado O; Lindén T; Connelly A; Wilson W; Howells DW; Churilov L; Ma H; Tse T; Rose S; Palmer S; Bougeat P; Campbell BCV; Christensen S; Macaulay SL; Favaloro J; O' Collins V; Mcbride S; Bates S; Cowley E; Dewey H; Wijeratne T; Gerraty R; Phan TG; Yan B; Parsons MW; Bladin C; Barber PA; Read S; Wong A; Lee A; Kleinig T; Hankey GJ; Blacker D; Markus R; Leyden J; Krause M; Grimley R; Mahant N; Jannes J; Sturm J; Davis SM; Donnan GA, 2013, 'STroke imAging pRevention and treatment (START): A longitudinal stroke cohort study: Clinical trials protocol', International Journal of Stroke, http://dx.doi.org/10.1111/ijs.12190

Bivard A; Parsons M, 2012, 'ASPECTaSaurus (a dinosaur)?', International Journal of Stroke, 7, pp. 564, http://dx.doi.org/10.1111/j.1747-4949.2012.00854.x

Holliday EG; Maguire JM; Evans TJ; Koblar SA; Jannes J; Sturm JW; Hankey GJ; Baker R; Golledge J; Parsons MW; Malik R; McEvoy M; Biros E; Lewis MD; Lincz LF; Peel R; Oldmeadow C; Smith W; Moscato P; Barlera S; Bevan S; Bis JC; Boerwinkle E; Boncoraglio GB; Brott TG; Brown RD; Cheng YC; Cole JW; Cotlarciuc I; Devan WJ; Fornage M; Furie KL; Grétarsdóttir S; Gschwendtner A; Ikram MA; Longstreth WT; Meschia JF; Mitchell BD; Mosley TH; Nalls MA; Parati EA; Psaty BM; Sharma P; Stefansson K; Thorleifsson G; Thorsteinsdottir U; Traylor M; Verhaaren BFJ; Wiggins KL; Worrall BB; Sudlow C; Rothwell PM; Farrall M; Dichgans M; Rosand J; Markus HS; Scott RJ; Levi C; Attia J, 2012, 'Common variants at 6p21.1 are associated with large artery atherosclerotic stroke', Nature Genetics, 44, pp. 1147 - 1151, http://dx.doi.org/10.1038/ng.2397

Campbell BCV; Christensen S; Levi CR; Desmond PM; Donnan GA; Davis SM; Parsons MW, 2012, 'Comparison of computed tomography perfusion and magnetic resonance imaging perfusion-diffusion mismatch in ischemic stroke', Stroke, 43, pp. 2648 - 2653, http://dx.doi.org/10.1161/STROKEAHA.112.660548

Arima H; Huang Y; Wang JG; Heeley E; Delcourt C; Parsons M; Li Q; Neal B; Chalmers J; Anderson C, 2012, 'Earlier blood pressure-lowering and greater attenuation of hematoma growth in acute intracerebral hemorrhage: INTERACT pilot phase', Stroke, 43, pp. 2236 - 2238, http://dx.doi.org/10.1161/STROKEAHA.112.651422

Parsons M; Levi C; Davis S, 2012, 'Tenecteplase versus Alteplase for Acute Ischemic Stroke REPLY', NEW ENGLAND JOURNAL OF MEDICINE, 367, pp. 276 - 276, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306522900019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Parsons M; Levi C; Davis S, 2012, 'The authors reply', New England Journal of Medicine, 367, pp. 276, http://dx.doi.org/10.1056/NEJMc1205829

Hankey GJ; Eikelboom JW; Yi Q; Lees KR; Chen C; Xavier D; Navarro JC; Ranawaka UK; Uddin W; Ricci S; Gommans J; Schmidt R; Gresele P, 2012, 'Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial', LANCET NEUROLOGY, 11, pp. 512 - 520, http://dx.doi.org/10.1016/S1474-4422(12)70091-1

Nagakane Y; Christensen S; Ogata T; Churilov L; Ma H; Parsons MW; Desmond PM; Levi CR; Butcher KS; Davis SM; Donnan GA, 2012, 'Moving beyond a single perfusion threshold to define penumbra: A novel probabilistic mismatch definition', Stroke, 43, pp. 1548 - 1555, http://dx.doi.org/10.1161/STROKEAHA.111.643932

O'Brien B; Parsons MW; Anderson CS, 2012, 'Sudden limb weakness', Medical Journal of Australia, 196, pp. 572 - 577, http://dx.doi.org/10.5694/mja12.10441

Hankey GJ; Patel MR; Stevens SR; Becker RC; Breithardt G; Carolei A; Diener H-C; Donnan GA; Halperin JL; Mahaffey KW; Mas J-L; Massaro A; Norrving B; Nessel CC; Paolini JF; Roine RO; Singer DE; Wong L; Califf RM; Fox KAA; Hacke W, 2012, 'Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF', LANCET NEUROLOGY, 11, pp. 315 - 322, http://dx.doi.org/10.1016/S1474-4422(12)70042-X

Parsons M; Spratt N; Bivard A; Campbell B; Chung K; Miteff F; O'Brien B; Bladin C; McElduff P; Allen C; Bateman G; Donnan G; Davis S; Levi C, 2012, 'A randomized trial of tenecteplase versus alteplase for acute ischemic stroke', New England Journal of Medicine, 366, pp. 1099 - 1107, http://dx.doi.org/10.1056/NEJMoa1109842

Ma H; Parsons MW; Christensen S; Campbell BCV; Churilov L; Connelly A; Yan B; Bladin C; Phan T; Barber AP; Read S; Hankey GJ; Markus R; Wijeratne T; Grimley R; Mahant N; Kleinig T; Sturm J; Lee A; Blacker D; Gerraty R; Krause M; Desmond PM; Mcbride SJ; Carey L; Howells DW; Hsu CY; Davis SM; Donnan GA, 2012, 'A multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits (EXTEND)', International Journal of Stroke, 7, pp. 74 - 80, http://dx.doi.org/10.1111/j.1747-4949.2011.00730.x

Campbell BCV; Tu HTH; Christensen S; Desmond PM; Levi CR; Bladin CF; Hjort N; Ashkanian M; Sølling C; Donnan GA; Davis SM; Østergaard L; Parsons MW, 2012, 'Assessing response to stroke thrombolysis: Validation of 24-hour multimodal magnetic resonance imaging', Archives of Neurology, 69, pp. 46 - 50, http://dx.doi.org/10.1001/archneurol.2011.232

Delcourt C; Huang Y; Arima H; Chalmers J; Davis SM; Heeley EL; Wang J; Parsons MW; Liu G; Anderson CS; INTERACT1 Investigators , 2012, 'Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study.', Neurology, 79, pp. 314 - 319, http://dx.doi.org/10.1212/WNL.0b013e318260cbba

Davis S; Campbell B; Christensen S; Ma H; Desmond P; Parsons M; Levi C; Bladin C; Barber PA; Donnan G, 2012, 'Perfusion/Diffusion Mismatch Is Valid and Should Be Used for Selecting Delayed Interventions', Translational Stroke Research, 3, pp. 188 - 197, http://dx.doi.org/10.1007/s12975-012-0167-8

Parsons MW; Levi CR, 2012, 'Reperfusion trials for acute ischaemic stroke', The Lancet, 380, pp. 706 - 708, http://dx.doi.org/10.1016/S0140-6736(12)61043-5

Sandercock P; Wardlaw JM; Lindley RI; Dennis M; Cohen G; Murray G; Innes K; Venables G; Czlonkowska A; Kobayashi A; Ricci S; Murray V; Berge E; Slot KB; Hankey GJ; Correia M; Peeters A; Matz K; Lyrer P; Gubitz G; Phillips SJ; Arauz A; Baigent C; Chadwick D; Tyrrell P; Lowe G; Collins R; Bath P; Van Gijn J; Gray R; Hart R; Yusuf S; Clark A; Perry D; Soosay V; Buchanan D; Grant S; Sakka E; Drever J; Walker P; Herath I; Brown AL; Chmielnik P; Armit C; Walton A; Hautvast M; Lewis S; Heron G; Odusanya S; Linksted P; Kane I; Whiteley W; Sellar R; White P; Keston P; Farrell A; Morris Z; Miranda H; Blackwell L, 2012, 'The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): A randomised controlled trial', The Lancet, 379, pp. 2352 - 2363, http://dx.doi.org/10.1016/S0140-6736(12)60768-5

Campbell BCV; Purushotham A; Christensen S; Desmond PM; Nagakane Y; Parsons MW; Lansberg MG; Mlynash M; Straka M; De Silva DA; Olivot JM; Bammer R; Albers GW; Donnan GA; Davis SM, 2012, 'The infarct core is well represented by the acute diffusion lesion: Sustained reversal is infrequent', Journal of Cerebral Blood Flow and Metabolism, 32, pp. 50 - 56, http://dx.doi.org/10.1038/jcbfm.2011.102

Levi C; Zareie H; Parsons M, 2012, 'Transcranial doppler in acute stroke management-A "real-time" bed-side guide to reperfusion and collateral flow', Perspectives in Medicine, 1-12, pp. 185 - 193, http://dx.doi.org/10.1016/j.permed.2012.02.044

Holliday EG; Maguire JM; Evans T-J; Golledge J; Biros E; Lewis MD; Koblar S; Jannes J; Hankey GJ; Baker R; Parsons MW; Sturm JW; Lincz LF; McEvoy M; Peel R; Moscato P; Scott RJ; Levi C; Attia J, 2012, 'Abstract 13: A Locus on Chromosome 6p21 is Associated with Large Artery Atherosclerotic Ischemic Stroke', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a13

Bivard A; Levi C; Parsons M, 2012, 'Abstract 2451: Arterial Spin Labelling Provides Usual Clinical Information In Acute Stroke', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a2451

Campbell BC; Christensen S; Levi CR; Desmond PM; Donnan GA; Davis SM; Parsons MW, 2012, 'Abstract 3200: Comparison of CT Perfusion Mismatch with Perfusion-Diffusion MRI in Ischemic Stroke - a Reliable Alternative?', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a3200

Christensen S; O'Brien B; Menon B; Bivard A; Campbell B; Desmond P; Davis S; Parsons M, 2012, 'Abstract 54: Mapping of Cerebral Vascular Territories Using Whole Brain Perfusion CT Imaging: A New Method', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a54

Parsons MW; Spratt N; Bivard A; Campbell B; Chung K; Miteff F; O'Brien B; McElduff P; Bladin C; Allen C; Bateman G; Donnan G; Davis S; Levi C, 2012, 'Abstract 57: Tenecteplase versus Alteplase for Acute Ischemic Stroke (TAAIS) trial: A Randomized Trial using Advanced CT Selection.', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a57

Picanco MR; Campbell BC; Christensen S; Desmond PM; Churilov L; De Silva DA; Butcher KS; Parsons MW; Levi CR; Barber PA; Bladin CF; Donnan GA; Davis SM, 2012, 'Abstract 61: Reperfusion Beyond 4.5 Hours Reduces Infarct Growth And Improves Clinical Outcome', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a61

Campbell BC; Christensen S; Parsons MW; Desmond PM; Barber PA; Butcher KS; Levi CR; De Silva DA; Lansberg MG; Mlynash M; Olivot J-M; Straka M; Bammer R; Albers GW; Donnan GA; Davis SM, 2012, 'Abstract 95: Regional Very Low Cerebral Blood Volume with Subsequent Local Reperfusion Predicts Hemorrhagic Transformation in Acute Ischemic Stroke', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a95

Campbell BCV; Christensen S; Levi CR; Desmond PM; Donnan GA; Davis SM; Parsons MW, 2011, 'Cerebral blood flow is the optimal CT perfusion parameter for assessing infarct core', Stroke, 42, pp. 3435 - 3440, http://dx.doi.org/10.1161/STROKEAHA.111.618355

Sandercock P; Lindley R; Wardlaw J; Dennis M; Innes K; Cohen G; Whiteley W; Perry D; Soosay V; Buchanan D; Venables G; Czlonkowska A; Kobayashi A; Berge E; Slot KB; Murray V; Peeters A; Hankey GJ; Matz K; Brainin M; Ricci S; Cantisani TA; Gubitz G; Phillips SJ; Antonio A; Correia M; Lyrer P; Kane I; Lundstrom E, 2011, 'Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited', TRIALS, 12, http://dx.doi.org/10.1186/1745-6215-12-252

Campbell BCV; Costello C; Christensen S; Ebinger M; Parsons MW; Desmond PM; Barber PA; Butcher KS; Levi CR; De Silva DA; Lansberg MG; Mlynash M; Olivot JM; Straka M; Bammer R; Albers GW; Donnan GA; Davis SM, 2011, 'Fluid-attenuated inversion recovery hyperintensity in acute ischemic stroke may not predict hemorrhagic transformation', Cerebrovascular Diseases, 32, pp. 401 - 405, http://dx.doi.org/10.1159/000331467

De Silva DA; Churilov L; Olivot JM; Christensen S; Lansberg MG; Mlynash M; Campbell BCV; Desmond P; Straka M; Bammer R; Albers GW; Davis SM; Donnan GA, 2011, 'Greater effect of stroke thrombolysis in the presence of arterial obstruction', Annals of Neurology, 70, pp. 601 - 605, http://dx.doi.org/10.1002/ana.22444

Hunter AJ; Snodgrass SJ; Quain D; Parsons MW; Levi CR, 2011, 'HOBOE (head-of-bed optimization of elevation) study: Association of higher angle with reduced cerebral blood flow velocity in acute ischemic stroke', Physical Therapy, 91, pp. 1503 - 1512, http://dx.doi.org/10.2522/ptj.20100271

Patel MR; Mahaffey KW; Garg J; Pan G; Singer DE; Hacke W; Breithardt G; Halperin JL; Hankey GJ; Piccini JP; Becker RC; Nessel CC; Paolini JF; Berkowitz SD; Fox KAA; Califf RM, 2011, 'Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation', NEW ENGLAND JOURNAL OF MEDICINE, 365, pp. 883 - 891, http://dx.doi.org/10.1056/NEJMoa1009638

Parsons MW, 2011, 'Advanced brain imaging studies should be performed in patients with suspected stroke presenting within 4.5 hours of symptom onset', Stroke, 42, pp. 2666 - 2667, http://dx.doi.org/10.1161/STROKEAHA.111.621771

Mcleod DD; Parsons MW; Levi CR; Beautement S; Buxton D; Roworth B; Spratt NJ, 2011, 'Establishing a rodent stroke perfusion computed tomography model', International Journal of Stroke, 6, pp. 284 - 289, http://dx.doi.org/10.1111/j.1747-4949.2010.00564.x

Thomas LC; Rivett DA; Attia JR; Parsons M; Levi C, 2011, 'Risk factors and clinical features of craniocervical arterial dissection', Manual Therapy, 16, pp. 351 - 356, http://dx.doi.org/10.1016/j.math.2010.12.008

Donnan GA; Davis SM; Parsons MW; Ma H; Dewey HM; Howells DW, 2011, 'How to make better use of thrombolytic therapy in acute ischemic stroke', Nature Reviews Neurology, 7, pp. 400 - 409, http://dx.doi.org/10.1038/nrneurol.2011.89

Bivard A; Spratt N; Levi CR; Parsons MW, 2011, 'Acute stroke thrombolysis: Time to dispense with the clock and move to tissue-based decision making?', Expert Review of Cardiovascular Therapy, 9, pp. 451 - 461, http://dx.doi.org/10.1586/erc.11.7

Gerstein HC; Miller ME; Genuth S; Ismail-Beigi F; Buse JB; Goff DC; Probstfield JL; Cushman WC; Ginsberg HN; Bigger JT; Grimm RH; Byington RP; Rosenberg YD; Friedewald WT, 2011, 'Long-Term Effects of Intensive Glucose Lowering on Cardiovascular Outcomes', NEW ENGLAND JOURNAL OF MEDICINE, 364, pp. 818 - 828, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287928400007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Simpson MA; Dewey HM; Parsons MW, 2011, 'In reply', Medical Journal of Australia, 194, pp. 212 - 213, http://dx.doi.org/10.5694/j.1326-5377.2011.tb03788.x

Bivard A; McElduff P; Spratt N; Levi C; Parsons M, 2011, 'Defining the extent of irreversible brain ischemia using perfusion computed tomography', Cerebrovascular Diseases, 31, pp. 238 - 245, http://dx.doi.org/10.1159/000321897

Parsons MW, 2011, 'Treating as early as possible with thrombolysis is crucial, but can we do better in the sub-4.5-hour time window?', Cerebrovascular Diseases, 31, pp. 229, http://dx.doi.org/10.1159/000322555

Nagakane Y; Christensen S; Brekenfeld C; Ma H; Churilov L; Parsons MW; Levi CR; Butcher KS; Peeters A; Barber PA; Bladin CF; De Silva DA; Fink J; Kimber TE; Schultz DW; Muir KW; Tress BM; Desmond PM; Davis SM; Donnan GA, 2011, 'EPITHET: Positive result after reanalysis using baseline diffusion-weighted imaging/perfusion-weighted imaging co-registration', Stroke, 42, pp. 59 - 64, http://dx.doi.org/10.1161/STROKEAHA.110.580464

Bivard A; Spratt N; Levi C; Parsons M, 2011, 'Perfusion computer tomography: Imaging and clinical validation in acute ischaemic stroke', Brain, 134, pp. 3408 - 3416, http://dx.doi.org/10.1093/brain/awr257

Garnett AR; Marsden DL; Parsons MW; Quain DA; Spratt NJ; Loudfoot AR; Middleton PM; Levi CR, 2010, 'The rural Prehospital Acute Stroke Triage (PAST) trial protocol: A controlled trial for rapid facilitated transport of rural acute stroke patients to a regional stroke centre', International Journal of Stroke, 5, pp. 506 - 513, http://dx.doi.org/10.1111/j.1747-4949.2010.00522.x

Arima H; Anderson CS; Wang JG; Huang Y; Heeley E; Neal B; Woodward M; Skulina C; Parsons MW; Peng B; Tao QL; Li YC; Jiang JD; Tai LW; Zhang JL; Xu E; Cheng Y; Morgenstern LB; Chalmers J, 2010, 'Lower treatment blood pressure is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage', Hypertension, 56, pp. 852 - 858, http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.154328

Marsden DL; Spratt NJ; Walker R; Barker D; Attia J; Pollack M; Parsons MW; Levi CR, 2010, 'Trends in stroke attack rates and case fatality in the Hunter Region, Australia 1996-2008', Cerebrovascular Diseases, 30, pp. 500 - 507, http://dx.doi.org/10.1159/000319022

Chemmanam T; Campbell BCV; Christensen S; Nagakane Y; Desmond PM; Bladin CF; Parsons MW; Levi CR; Barber PA; Donnan GA; Davis SM, 2010, 'Ischemic diffusion lesion reversal is uncommon and rarely alters perfusion-diffusion mismatch', Neurology, 75, pp. 1040 - 1047, http://dx.doi.org/10.1212/WNL.0b013e3181f39ab6

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