By Professor Mark Parsons

Journal articles

Ma H; Parsons MW; Christensen S; Campbell BCV; Churilov L; Connelly A; Yan B; Bladin C; Phan T; Barber AP; Read S; Hankey GJ; Markus R; Wijeratne T; Grimley R; Mahant N; Kleinig T; Sturm J; Lee A; Blacker D; Gerraty R; Krause M; Desmond PM; Mcbride SJ; Carey L; Howells DW; Hsu CY; Davis SM; Donnan GA, 2012, 'A multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits (EXTEND)', International Journal of Stroke, 7, pp. 74 - 80, http://dx.doi.org/10.1111/j.1747-4949.2011.00730.x

Campbell BCV; Tu HTH; Christensen S; Desmond PM; Levi CR; Bladin CF; Hjort N; Ashkanian M; Sølling C; Donnan GA; Davis SM; Østergaard L; Parsons MW, 2012, 'Assessing response to stroke thrombolysis: Validation of 24-hour multimodal magnetic resonance imaging', Archives of Neurology, 69, pp. 46 - 50, http://dx.doi.org/10.1001/archneurol.2011.232

Delcourt C; Huang Y; Arima H; Chalmers J; Davis SM; Heeley EL; Wang J; Parsons MW; Liu G; Anderson CS; INTERACT1 Investigators , 2012, 'Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study.', Neurology, 79, pp. 314 - 319, http://dx.doi.org/10.1212/WNL.0b013e318260cbba

Davis S; Campbell B; Christensen S; Ma H; Desmond P; Parsons M; Levi C; Bladin C; Barber PA; Donnan G, 2012, 'Perfusion/Diffusion Mismatch Is Valid and Should Be Used for Selecting Delayed Interventions', Translational Stroke Research, 3, pp. 188 - 197, http://dx.doi.org/10.1007/s12975-012-0167-8

Parsons MW; Levi CR, 2012, 'Reperfusion trials for acute ischaemic stroke', The Lancet, 380, pp. 706 - 708, http://dx.doi.org/10.1016/S0140-6736(12)61043-5

Sandercock P; Wardlaw JM; Lindley RI; Dennis M; Cohen G; Murray G; Innes K; Venables G; Czlonkowska A; Kobayashi A; Ricci S; Murray V; Berge E; Slot KB; Hankey GJ; Correia M; Peeters A; Matz K; Lyrer P; Gubitz G; Phillips SJ; Arauz A; Baigent C; Chadwick D; Tyrrell P; Lowe G; Collins R; Bath P; Van Gijn J; Gray R; Hart R; Yusuf S; Clark A; Perry D; Soosay V; Buchanan D; Grant S; Sakka E; Drever J; Walker P; Herath I; Brown AL; Chmielnik P; Armit C; Walton A; Hautvast M; Lewis S; Heron G; Odusanya S; Linksted P; Kane I; Whiteley W; Sellar R; White P; Keston P; Farrell A; Morris Z; Miranda H; Blackwell L, 2012, 'The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): A randomised controlled trial', The Lancet, 379, pp. 2352 - 2363, http://dx.doi.org/10.1016/S0140-6736(12)60768-5

Campbell BCV; Purushotham A; Christensen S; Desmond PM; Nagakane Y; Parsons MW; Lansberg MG; Mlynash M; Straka M; De Silva DA; Olivot JM; Bammer R; Albers GW; Donnan GA; Davis SM, 2012, 'The infarct core is well represented by the acute diffusion lesion: Sustained reversal is infrequent', Journal of Cerebral Blood Flow and Metabolism, 32, pp. 50 - 56, http://dx.doi.org/10.1038/jcbfm.2011.102

Levi C; Zareie H; Parsons M, 2012, 'Transcranial doppler in acute stroke management-A "real-time" bed-side guide to reperfusion and collateral flow', Perspectives in Medicine, 1-12, pp. 185 - 193, http://dx.doi.org/10.1016/j.permed.2012.02.044

Holliday EG; Maguire JM; Evans T-J; Golledge J; Biros E; Lewis MD; Koblar S; Jannes J; Hankey GJ; Baker R; Parsons MW; Sturm JW; Lincz LF; McEvoy M; Peel R; Moscato P; Scott RJ; Levi C; Attia J, 2012, 'Abstract 13: A Locus on Chromosome 6p21 is Associated with Large Artery Atherosclerotic Ischemic Stroke', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a13

Bivard A; Levi C; Parsons M, 2012, 'Abstract 2451: Arterial Spin Labelling Provides Usual Clinical Information In Acute Stroke', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a2451

Campbell BC; Christensen S; Levi CR; Desmond PM; Donnan GA; Davis SM; Parsons MW, 2012, 'Abstract 3200: Comparison of CT Perfusion Mismatch with Perfusion-Diffusion MRI in Ischemic Stroke - a Reliable Alternative?', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a3200

Christensen S; O'Brien B; Menon B; Bivard A; Campbell B; Desmond P; Davis S; Parsons M, 2012, 'Abstract 54: Mapping of Cerebral Vascular Territories Using Whole Brain Perfusion CT Imaging: A New Method', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a54

Parsons MW; Spratt N; Bivard A; Campbell B; Chung K; Miteff F; O'Brien B; McElduff P; Bladin C; Allen C; Bateman G; Donnan G; Davis S; Levi C, 2012, 'Abstract 57: Tenecteplase versus Alteplase for Acute Ischemic Stroke (TAAIS) trial: A Randomized Trial using Advanced CT Selection.', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a57

Picanco MR; Campbell BC; Christensen S; Desmond PM; Churilov L; De Silva DA; Butcher KS; Parsons MW; Levi CR; Barber PA; Bladin CF; Donnan GA; Davis SM, 2012, 'Abstract 61: Reperfusion Beyond 4.5 Hours Reduces Infarct Growth And Improves Clinical Outcome', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a61

Campbell BC; Christensen S; Parsons MW; Desmond PM; Barber PA; Butcher KS; Levi CR; De Silva DA; Lansberg MG; Mlynash M; Olivot J-M; Straka M; Bammer R; Albers GW; Donnan GA; Davis SM, 2012, 'Abstract 95: Regional Very Low Cerebral Blood Volume with Subsequent Local Reperfusion Predicts Hemorrhagic Transformation in Acute Ischemic Stroke', Stroke, 43, http://dx.doi.org/10.1161/str.43.suppl_1.a95

Campbell BCV; Christensen S; Levi CR; Desmond PM; Donnan GA; Davis SM; Parsons MW, 2011, 'Cerebral blood flow is the optimal CT perfusion parameter for assessing infarct core', Stroke, 42, pp. 3435 - 3440, http://dx.doi.org/10.1161/STROKEAHA.111.618355

Sandercock P; Lindley R; Wardlaw J; Dennis M; Innes K; Cohen G; Whiteley W; Perry D; Soosay V; Buchanan D; Venables G; Czlonkowska A; Kobayashi A; Berge E; Slot KB; Murray V; Peeters A; Hankey GJ; Matz K; Brainin M; Ricci S; Cantisani TA; Gubitz G; Phillips SJ; Antonio A; Correia M; Lyrer P; Kane I; Lundstrom E, 2011, 'Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited', TRIALS, 12, http://dx.doi.org/10.1186/1745-6215-12-252

Campbell BCV; Costello C; Christensen S; Ebinger M; Parsons MW; Desmond PM; Barber PA; Butcher KS; Levi CR; De Silva DA; Lansberg MG; Mlynash M; Olivot JM; Straka M; Bammer R; Albers GW; Donnan GA; Davis SM, 2011, 'Fluid-attenuated inversion recovery hyperintensity in acute ischemic stroke may not predict hemorrhagic transformation', Cerebrovascular Diseases, 32, pp. 401 - 405, http://dx.doi.org/10.1159/000331467

De Silva DA; Churilov L; Olivot JM; Christensen S; Lansberg MG; Mlynash M; Campbell BCV; Desmond P; Straka M; Bammer R; Albers GW; Davis SM; Donnan GA, 2011, 'Greater effect of stroke thrombolysis in the presence of arterial obstruction', Annals of Neurology, 70, pp. 601 - 605, http://dx.doi.org/10.1002/ana.22444

Hunter AJ; Snodgrass SJ; Quain D; Parsons MW; Levi CR, 2011, 'HOBOE (head-of-bed optimization of elevation) study: Association of higher angle with reduced cerebral blood flow velocity in acute ischemic stroke', Physical Therapy, 91, pp. 1503 - 1512, http://dx.doi.org/10.2522/ptj.20100271

Patel MR; Mahaffey KW; Garg J; Pan G; Singer DE; Hacke W; Breithardt G; Halperin JL; Hankey GJ; Piccini JP; Becker RC; Nessel CC; Paolini JF; Berkowitz SD; Fox KAA; Califf RM, 2011, 'Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation', NEW ENGLAND JOURNAL OF MEDICINE, 365, pp. 883 - 891, http://dx.doi.org/10.1056/NEJMoa1009638

Parsons MW, 2011, 'Advanced brain imaging studies should be performed in patients with suspected stroke presenting within 4.5 hours of symptom onset', Stroke, 42, pp. 2666 - 2667, http://dx.doi.org/10.1161/STROKEAHA.111.621771

Mcleod DD; Parsons MW; Levi CR; Beautement S; Buxton D; Roworth B; Spratt NJ, 2011, 'Establishing a rodent stroke perfusion computed tomography model', International Journal of Stroke, 6, pp. 284 - 289, http://dx.doi.org/10.1111/j.1747-4949.2010.00564.x

Thomas LC; Rivett DA; Attia JR; Parsons M; Levi C, 2011, 'Risk factors and clinical features of craniocervical arterial dissection', Manual Therapy, 16, pp. 351 - 356, http://dx.doi.org/10.1016/j.math.2010.12.008

Donnan GA; Davis SM; Parsons MW; Ma H; Dewey HM; Howells DW, 2011, 'How to make better use of thrombolytic therapy in acute ischemic stroke', Nature Reviews Neurology, 7, pp. 400 - 409, http://dx.doi.org/10.1038/nrneurol.2011.89

Bivard A; Spratt N; Levi CR; Parsons MW, 2011, 'Acute stroke thrombolysis: Time to dispense with the clock and move to tissue-based decision making?', Expert Review of Cardiovascular Therapy, 9, pp. 451 - 461, http://dx.doi.org/10.1586/erc.11.7

Gerstein HC; Miller ME; Genuth S; Ismail-Beigi F; Buse JB; Goff DC; Probstfield JL; Cushman WC; Ginsberg HN; Bigger JT; Grimm RH; Byington RP; Rosenberg YD; Friedewald WT, 2011, 'Long-Term Effects of Intensive Glucose Lowering on Cardiovascular Outcomes', NEW ENGLAND JOURNAL OF MEDICINE, 364, pp. 818 - 828, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287928400007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Simpson MA; Dewey HM; Parsons MW, 2011, 'In reply', Medical Journal of Australia, 194, pp. 212 - 213, http://dx.doi.org/10.5694/j.1326-5377.2011.tb03788.x

Bivard A; McElduff P; Spratt N; Levi C; Parsons M, 2011, 'Defining the extent of irreversible brain ischemia using perfusion computed tomography', Cerebrovascular Diseases, 31, pp. 238 - 245, http://dx.doi.org/10.1159/000321897

Parsons MW, 2011, 'Treating as early as possible with thrombolysis is crucial, but can we do better in the sub-4.5-hour time window?', Cerebrovascular Diseases, 31, pp. 229, http://dx.doi.org/10.1159/000322555

Nagakane Y; Christensen S; Brekenfeld C; Ma H; Churilov L; Parsons MW; Levi CR; Butcher KS; Peeters A; Barber PA; Bladin CF; De Silva DA; Fink J; Kimber TE; Schultz DW; Muir KW; Tress BM; Desmond PM; Davis SM; Donnan GA, 2011, 'EPITHET: Positive result after reanalysis using baseline diffusion-weighted imaging/perfusion-weighted imaging co-registration', Stroke, 42, pp. 59 - 64, http://dx.doi.org/10.1161/STROKEAHA.110.580464

Bivard A; Spratt N; Levi C; Parsons M, 2011, 'Perfusion computer tomography: Imaging and clinical validation in acute ischaemic stroke', Brain, 134, pp. 3408 - 3416, http://dx.doi.org/10.1093/brain/awr257

Garnett AR; Marsden DL; Parsons MW; Quain DA; Spratt NJ; Loudfoot AR; Middleton PM; Levi CR, 2010, 'The rural Prehospital Acute Stroke Triage (PAST) trial protocol: A controlled trial for rapid facilitated transport of rural acute stroke patients to a regional stroke centre', International Journal of Stroke, 5, pp. 506 - 513, http://dx.doi.org/10.1111/j.1747-4949.2010.00522.x

Arima H; Anderson CS; Wang JG; Huang Y; Heeley E; Neal B; Woodward M; Skulina C; Parsons MW; Peng B; Tao QL; Li YC; Jiang JD; Tai LW; Zhang JL; Xu E; Cheng Y; Morgenstern LB; Chalmers J, 2010, 'Lower treatment blood pressure is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage', Hypertension, 56, pp. 852 - 858, http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.154328

Marsden DL; Spratt NJ; Walker R; Barker D; Attia J; Pollack M; Parsons MW; Levi CR, 2010, 'Trends in stroke attack rates and case fatality in the Hunter Region, Australia 1996-2008', Cerebrovascular Diseases, 30, pp. 500 - 507, http://dx.doi.org/10.1159/000319022

Chemmanam T; Campbell BCV; Christensen S; Nagakane Y; Desmond PM; Bladin CF; Parsons MW; Levi CR; Barber PA; Donnan GA; Davis SM, 2010, 'Ischemic diffusion lesion reversal is uncommon and rarely alters perfusion-diffusion mismatch', Neurology, 75, pp. 1040 - 1047, http://dx.doi.org/10.1212/WNL.0b013e3181f39ab6

Ahmed N; Wahlgren N; Grond M; Hennerici M; Lees KR; Mikulik R; Parsons M; Roine RO; Toni D; Ringleb P, 2010, 'Implementation and outcome of thrombolysis with alteplase 3-4·5 h after an acute stroke: an updated analysis from SITS-ISTR', The Lancet Neurology, 9, pp. 866 - 874, http://dx.doi.org/10.1016/S1474-4422(10)70165-4

Tu HTH; Campbell BCV; Christensen S; Collins M; De Silva DA; Butcher KS; Parsons MW; Desmond PM; Barber PA; Levi CR; Bladin CF; Donnan GA; Davis SM, 2010, 'Pathophysiological determinants of worse stroke outcome in atrial fibrillation', Cerebrovascular Diseases, 30, pp. 389 - 395, http://dx.doi.org/10.1159/000316886

Pickering RL; Hubbard IJ; Baker KG; Parsons MW, 2010, 'Assessment of the upper limb in acute stroke: The validity of hierarchal scoring for the Motor Assessment Scale', Australian Occupational Therapy Journal, 57, pp. 174 - 182, http://dx.doi.org/10.1111/j.1440-1630.2009.00810.x

Parsons MW; Christensen S; McElduff P; Levi CR; Butcher KS; De Silva DA; Ebinger M; Barber PA; Bladin C; Donnan GA; Davis SM, 2010, 'Pretreatment diffusion-and perfusion-MR lesion volumes have a crucial influence on clinical response to stroke thrombolysis', Journal of Cerebral Blood Flow and Metabolism, 30, pp. 1214 - 1225, http://dx.doi.org/10.1038/jcbfm.2010.3

Lees KR; Bluhmki E; von Kummer R; Brott TG; Toni D; Grotta JC; Albers GW; Kaste M; Marler JR; Hamilton SA; Tilley BC; Davis SM; Donnan GA; Hacke W; Ninds EA, 2010, 'Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials', LANCET, 375, pp. 1695 - 1703, http://dx.doi.org/10.1016/S0140-6736(10)60491-6

Johnston KC; Parsons M, 2010, 'Aggressive glucose control in acute stroke is the answer in the imaging?', Annals of Neurology, 67, pp. 557 - 558, http://dx.doi.org/10.1002/ana.22046

Parsons MW, 2010, 'Commentary: Echocardiography in the detection of cardioembolism in a stroke population', Journal of Clinical Neuroscience, 17, pp. 566, http://dx.doi.org/10.1016/j.jocn.2010.01.001

Campbell BCV; Christensen S; Foster SJ; Desmond PM; Parsons MW; Butcher KS; Barber PA; Levi CR; Bladin CF; Donnan GA; Davis SM, 2010, 'Visual assessment of perfusion-diffusion mismatch is inadequate to select patients for thrombolysis for the epithet investigators', Cerebrovascular Diseases, 29, pp. 592 - 596, http://dx.doi.org/10.1159/000311080

Parsons M, 2010, 'Portable computed tomography scanners in community hospitals: Are they necessary?', International Journal of Stroke, 5, pp. 67 - 67, http://dx.doi.org/10.1111/j.1747-4949.2010.00407.x

Delcourt C; Huang Y; Wang J; Heeley E; Lindley R; Stapf C; Tzourio C; Arima H; Parsons M; Sun J; Neal B; Chalmers J; Anderson C, 2010, 'The second (main) phase of an open, randomised, multicentre study to investigate the effectiveness of an intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT2)', International Journal of Stroke, 5, pp. 110 - 116, http://dx.doi.org/10.1111/j.1747-4949.2010.00415.x

Anderson CS; Huang Y; Arima H; Heeley E; Skulina C; Parsons MW; Peng B; Li Q; Su S; Tao QL; Li YC; Jiang JD; Tai LW; Zhang JL; Xu E; Cheng Y; Morgenstern LB; Chalmers J; Wang JG, 2010, 'Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: The intensive blood pressure reduction in acute cérébral haemorrhage trial (INTERACT)', Stroke, 41, pp. 307 - 312, http://dx.doi.org/10.1161/STROKEAHA.109.561795

De Silva DA; Brekenfeld C; Ebinger M; Christensen S; Barber PA; Butcher KS; Levi CR; Parsons MW; Bladin CF; Donnan GA; Davis SM, 2010, 'The benefits of intravenous thrombolysis relate to the site of baseline arterial occlusion in the echoplanar imaging thrombolytic evaluation trial (EPITHET)', Stroke, 41, pp. 295 - 299, http://dx.doi.org/10.1161/STROKEAHA.109.562827

Hankey GJ; Eikelboom JW; Baker RI; Gelavis A; Hickling SC; Jamrozik K; van Bockxmeer FM; Vasikaran S; Chen C; Lees KR; Yi Q; Algra A; Wong MC; Cheung R; Wong L; Divjak I; Ferro J; de Freitas G; Gommans J; Groppa S; Hill M; Spence JD; Lisheng L; Navarro J; Ranawaka U; Ricci S; Schmidt R; Slivka A; Tan K; Tsiskaridze A; Uddin W; Vanhooren G; Xavier D; Armitage J; Hobbs M; Le M; Sudlow C; Wheatley K; Yi Q; Brown W; Bulder M; Ho WK; Klijn CJM; Koedam E; Langton P; Nijboer E; Tuch P; Pizzi J; Tang M; Alaparthi R; Antenucci M; Chew Y; Chinnery D; Cockayne C; Holt R; Loh K; McMullin L; Mulholland G; Nahoo B; Read E; Smith F; Yip CY; Crimmins D; Davis T; England M; Rakic V; Schultz DW; Frayne J; Bladin C; Kokkinos J; Dunbabin D; Harper J; Rees P; Warden D; Levi C; Parsons M; Russell M; Spratt N; Clayton P; Nayagam P; Sharp J; Grainger K; de Wytt C; McDougall A; Donnan GA; Grimley R; Neynens E; Reinhart B; Ropele S; Stögerer E; Dedeken P; Schelstraete C; Veyt A; Andre C; de Freitas GR; Gomes SE; Mok VCT; Wong A; Wong LKS, 2010, 'B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins to prevent stroke (VITATOPS) trial: A randomised, double-blind, parallel, placebo-controlled trial', The Lancet Neurology, 9, pp. 855 - 865, http://dx.doi.org/10.1016/S1474-4422(10)70187-3

Butcher K; Christensen S; Parsons M; De Silva DA; Ebinger M; Levi C; Jeerakathil T; Campbell BCV; Barber PA; Bladin C; Fink J; Tress B; Donnan GA; Davis SM, 2010, 'Postthrombolysis blood pressure elevation is associated with hemorrhagic transformation', Stroke, 41, pp. 72 - 77, http://dx.doi.org/10.1161/STROKEAHA.109.563767

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