By Professor Merlin Crossley

Journal articles

Turner J; Crossley M, 2001, 'The CtBP family: Enigmatic and enzymatic transcriptional co-repressors', BioEssays, 23, pp. 683 - 690, http://dx.doi.org/10.1002/bies.1097

Schuierer M; Hilger-Eversheim K; Dobner T; Bosserhoff AK; Moser M; Turner J; Crossley M; Buettner R, 2001, 'Induction of AP-2α Expression by Adenoviral Infection Involves Inactivation of the AP-2rep Transcriptional Corepressor CtBP1', Journal of Biological Chemistry, 276, pp. 27944 - 27949, http://dx.doi.org/10.1074/jbc.M100070200

Palmer S; Brouillet JP; Kilbey A; Fulton R; Walker M; Crossley M; Bartholomew C, 2001, 'Evi-1 Transforming and Repressor Activities are Mediated by CtBP Co-repressor Proteins', Journal of Biological Chemistry, 276, pp. 25834 - 25840, http://dx.doi.org/10.1074/jbc.M102343200

Crossley M, 2001, 'Transcription of the genome: Don't read it all at once', Genome Biology, 2

Chu Kong Liew ; Kowalski K; Fox AH; Newton A; Sharpe BK; Crossley M; Mackay JP, 2000, 'Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions', Structure, 8, pp. 1157 - 1166, http://dx.doi.org/10.1016/S0969-2126(00)00527-X

Newton AL; Sharped BK; Kwan A; Mackay JP; Crossley M, 2000, 'The transactivation domain within cysteine/histidine-rich region 1 of CBP comprises two novel zinc-binding modules', Journal of Biological Chemistry, 275, pp. 15128 - 15134, http://dx.doi.org/10.1074/jbc.M910396199

Van Vliet J; Turner J; Crossley M, 2000, 'Human Kruppel-like Factor 8: A CACCC-box binding protein that associates with CtBP and represses transcription', Nucleic Acids Research, 28, pp. 1955 - 1962, http://dx.doi.org/10.1093/nar/28.9.1955

Matthews JM; Kowalski K; Liew CK; Sharpe BK; Fox AH; Crossley M; Mackay JP, 2000, 'A class of zinc fingers involved in protein-protein interactions', European Journal of Biochemistry, 267, pp. 1030 - 1038, http://dx.doi.org/10.1046/j.1432-1327.2000.01095.x

Perdomo J; Holmes ML; Chong BH; Crossley M, 2000, 'Eos and Pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities', The Journal of Biological Chemistry, pp. 38347 - 38354

Turner J; Crossley M, 1999, 'Mammalian Kruppel-like transcription factors: More than just a pretty finger', Trends in Biochemical Sciences, 24, pp. 236 - 240, http://dx.doi.org/10.1016/S0968-0004(99)01406-1

Fox AH; Holmes M; MacKay J; Crossley M, 1999, 'The activity of FOG-1 is potentiated by its ability to contact GATA-1 through multiple zinc fingers', Biochemical Society Transactions, 27, pp. A99 - A99, http://dx.doi.org/10.1042/bst027a099c

Kowalski K; Czolij R; King GF; Crossley M; Mackay JP, 1999, 'The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG', Journal of Biomolecular NMR, 13, pp. 249 - 262, http://dx.doi.org/10.1023/A:1008309602929

Turner J; Crossley M, 1999, 'Basic Kruppel-like factor functions within a network of interacting haematopoietic transcription factors', International Journal of Biochemistry and Cell Biology, 31, pp. 1169 - 1174, http://dx.doi.org/10.1016/S1357-2725(99)00067-9

Holmes ML; Turner J; Fox A; Chisholm OT; Crossley M; Chong BH, 1999, 'hFOG-2, a novel zinc finger protein, binds the corepressor mCtBP2 and modulates GATAmediated activation', The Journal of Biological Chemistry, pp. 23491 - 23498

Fox A; Liew C; Holmes ML; Kowalski K; Mackay J; Crossley M, 1999, 'Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers', European Molecular Biology Organization, 18, pp. 2812 - 2822

Fox AH; Kowalski K; King GF; Mackay JP; Crossley M, 1998, 'Key residues characteristic of GATA N-fingers are recognized by FOG', Journal of Biological Chemistry, 273, pp. 33595 - 33603, http://dx.doi.org/10.1074/jbc.273.50.33595

Mackay JP; Kowalski K; Fox AH; Czolij R; King GF; Crossley M, 1998, 'Involvement of the N-finger in the self-association of GATA-1', Journal of Biological Chemistry, 273, pp. 30560 - 30567, http://dx.doi.org/10.1074/jbc.273.46.30560

Spadaccini A; Tilbrook PA; Sarna MK; Crossley M; Bieke JJ; Klinken SP, 1998, 'Transcription factor erythroid Kruppel-like factor (ELKF) is essential for the erythropoietin-induced hemoglobin production but not for proliferation, viability, or morphological maturation', Journal of Biological Chemistry, 273, pp. 23793 - 23798, http://dx.doi.org/10.1074/jbc.273.37.23793

Turner J; Crossley M, 1998, 'Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators', EMBO Journal, 17, pp. 5129 - 5140, http://dx.doi.org/10.1093/emboj/17.17.5129

Bradbury RA; Sunn KL; Crossley M; Bai M; Brown EM; Delbridge L; Conigrave AD, 1998, 'Expression of the parathyroid Ca²⁺-sensing receptor in cytotrophoblasts from human term placenta', Journal of Endocrinology, 156, pp. 425 - 430, http://dx.doi.org/10.1677/joe.0.1560425

Mackay JP; Crossley M, 1998, 'Zinc fingers are sticking together', Trends in Biochemical Sciences, 23, pp. 1 - 4, http://dx.doi.org/10.1016/S0968-0004(97)01168-7

Tsang AP; Visvader JE; Turner CA; Fujiwara Y; Yu C; Weiss MJ; Crossley M; Orkin SH, 1997, 'FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation', Cell, 90, pp. 109 - 119, http://dx.doi.org/10.1016/S0092-8674(00)80318-9

Crossley M; Whitelaw E; Perkins A; Williams G; Fujiwara Y; Orkin SH, 1996, 'Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells', Molecular and Cellular Biology, 16, pp. 1695 - 1705, http://dx.doi.org/10.1128/MCB.16.4.1695

Crossley M; Merika M; Orkin SH, 1995, 'Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domains', Molecular and Cellular Biology, 15, pp. 2448 - 2456, http://dx.doi.org/10.1128/MCB.15.5.2448

Visvader JE; Crossley M; Hill J; Orkin SH; Adams JM, 1995, 'The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line', Molecular and Cellular Biology, 15, pp. 634 - 641, http://dx.doi.org/10.1128/mcb.15.2.634

Crossley M; Orkin SH, 1994, 'Phosphorylation of the erythroid transcription factor GATA-1', Journal of Biological Chemistry, 269, pp. 16589 - 16596

Crossley M; Tsang AP; Bieker JJ; Orkin SH, 1994, 'Regulation of the erythroid Kruppel-like factor (EKLF) gene promoter by the erythroid transcription factor GATA-1', Journal of Biological Chemistry, 269, pp. 15440 - 15444

Crossley M; Orkin SH, 1993, 'Regulation of the β-globin locus', Current Opinion in Genetics and Development, 3, pp. 232 - 237, http://dx.doi.org/10.1016/0959-437X(93)90028-N

Crossley M; Ludwig M; Stowell KM; De Vos P; Olek K; Brownlee GG, 1992, 'Recovery from hemophilia B Leyden: An androgen responsive element in the factor IX promoter', Science, 257, pp. 377 - 379, http://dx.doi.org/10.1126/science.1631558

Pang CP; Crossley M; Kent G; Brownlee GG, 1990, 'Comparative sequence analysis of mammalian factor IX promoters', Nucleic Acids Research, 18, pp. 6731 - 6732, http://dx.doi.org/10.1093/nar/18.22.6731

Crossley M; Winship PR; Austen DEG; Rizza CR; Brownlee GG, 1990, 'A less severe form of haemophilia B leyden', Nucleic Acids Research, 18, pp. 4633, http://dx.doi.org/10.1093/nar/18.15.4633

Crossley M; Brownlee GG, 1990, 'Disruption of a C/EBP binding site in the factor IX promoter is associated with haemophilia B', Nature, 345, pp. 444 - 446, http://dx.doi.org/10.1038/345444a0

CROSSLEY PM; WINSHIP PR; BLACK A; RIZZA CR; BROWNLEE GG, 1989, 'UNUSUAL CASE OF HAEMOPHILIA-B', LANCET, 1, pp. 960 - 960, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1989U400800034&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers

Ilsley M; Gillinder KR; Magor G; Crossley M; Perkins AC, 2016, 'Fine-Tuning Erythropoiesis By Competition Between Kruppel-like Factors for Promoters and Enhancers', in BLOOD, AMER SOC HEMATOLOGY, CA, San Diego, presented at 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), CA, San Diego, 03 December 2016 - 06 December 2016, http://dx.doi.org/10.1182/blood.V128.22.1036.1036

Yucel D; Llamosas E; Crossley M; Nicholas H, 2012, 'The regulation of C-terminal Binding Protein (CtBP) by a putative chromatin modifier', in JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE BV, TURKEY, Erciyes Univ, Kayseri, pp. 13 - 13, presented at Eurobiotech Agriculture Symposium, TURKEY, Erciyes Univ, Kayseri, 12 April 2012 - 14 April 2012, http://dx.doi.org/10.1016/j.jbiotec.2012.07.014

Winteringham LN; Endersby R; Beaumont J; Lalonde J; Crossley M; Klinken SP, 2010, 'HLS5, A NOVEL UBIQUITIN E3 LIGASE, MODULATES LEVELS OF SUMOYLATED GATA-1 AND REGULATES ERYTHROID PROGENITOR CELL DIFFERENTIATION', in EXPERIMENTAL HEMATOLOGY, ELSEVIER SCIENCE INC, AUSTRALIA, Melbourne, pp. S57 - S57, presented at 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells, AUSTRALIA, Melbourne, 15 September 2010 - 18 September 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000281168900116&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Winteringham LN; Endersby R; Beaumont J; Lalonde J-P; Crossley M; Klinken SP, 2009, 'Hls5, a Novel Ubiquitin E3 Ligase, Modulates Levels of Sumoylated GATA-1', in BLOOD, AMER SOC HEMATOLOGY, LA, New Orleans, pp. 108 - 108, presented at 51st Annual Meeting of the American-Society-of-Hematology, LA, New Orleans, 05 December 2009 - 08 December 2009, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000272725800254&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Crossley M, 2003, 'Unscrambling the genome', in Genome Biology, http://dx.doi.org/10.1186/gb-2003-4-5-320

Turner J; Holmes M; Czolij R; Gaensler K; Yang HD; Fujiwara Y; Chong B; Koh P; Perkins A; Orkin S; Crossley M, 2002, 'Basic Kruppel-like factor recruits multiple co-repressors to silence gene expression.', in BLOOD CELLS MOLECULES AND DISEASES, ACADEMIC PRESS INC ELSEVIER SCIENCE, ENGLAND, OXFORD, pp. 135 - 136, presented at 13th Conference on Hemoglobin Switching, ENGLAND, OXFORD, 26 September 2002 - 30 September 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000184101400050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Crossley M, 2002, 'Genome packaging and expression', in Genome Biology

Conference Abstracts

Masuda T; Wang X; Maeda M; Canver MC; Sher F; Funnell APW; Fisher C; Suciu M; Martyn GE; Norton LJ; Zhu R; Kurita R; Nakamura Y; Xu J; Higgs DR; Crossley M; Bauer DE; Orkin SH; Kharchenko PV; Maeda T, 2015, 'The LRF/ZBTB7A Transcription Factor Is a BCL11A-Independent Repressor of Fetal Hemoglobin', in BLOOD, AMER SOC HEMATOLOGY, FL, Orlando, Vol. 126, presented at 57th Annual Meeting of the American-Society-of-Hematology, FL, Orlando, 05 December 2015 - 08 December 2015, http://dx.doi.org/10.1182/blood.V126.23.2.2

Preprints

Xu S; Ren R; Peng C; Lu H; Ly LC; Crossley M; Xu B; Cheng X; Blobel GA; Lan X, 2024, Mechanistic dissection of theCHD4enhancers reveals cooperative functions among the homotypic ZNF410 clustered motifs, http://dx.doi.org/10.1101/2024.02.24.581901

Lan X; Ren R; Feng R; Ly LC; Lan Y; Zhang Z; Aboreden N; Qin K; Horton JR; Grevet JD; Mayuranathan T; Abdulmalik O; Keller CA; Giardine B; Hardison RC; Crossley M; Weiss MJ; Cheng X; Shi J; Blobel GA, 2020, ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression, http://dx.doi.org/10.1101/2020.08.31.274324

Other

Fan Y; Crossley M; Johnston E, 2019, Male teachers are most likely to rate highly in university student feedback, https://theconversation.com/male-teachers-are-most-likely-to-rate-highly-in-university-student-feedback-111741

Mak KS; Burdach J; Norton LJ; Pearson RCM; Crossley M; Funnell APW, 2016, Erratum to: Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor [Genome Biology, 15 (2014) R58], http://dx.doi.org/10.1186/s13059-016-0977-1

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