By Professor Michael John Rogers

Journal articles

Russell RGG; Rogers MJ, 1999, 'Bisphosphonates: From the laboratory to the clinic and back again', Bone, 25, pp. 97 - 106, http://dx.doi.org/10.1016/S8756-3282(99)00116-7

Mönkkönen J; Makronen N; Rogers MJ; Frith JC; Auriola S, 1999, 'Effects of bisphosphonates on the inflammatory processes of activated macrophages', Phosphorus, Sulfur and Silicon and Related Elements, 144-146, pp. 321 - 324, http://dx.doi.org/10.1080/10426509908546246

Benford HL; Frith JC; Auriola S; Mönkkönen J; Rogers MJ, 1999, 'Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: Biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs', Molecular Pharmacology, 56, pp. 131 - 140, http://dx.doi.org/10.1124/mol.56.1.131

Rogers MJ; Frith JC; Luckman SP; Coxon FP; Benford HL; M̈onkk̈onen J; Auriola S; Chilton KM; Russell RGG, 1999, 'Molecular mechanisms of action of bisphosphonates', Bone, 24, pp. 73S - 79S, http://dx.doi.org/10.1016/S8756-3282(99)00070-8

Shipman CM; Croucher PI; Russell RGG; Helfrich MH; Rogers MJ, 1998, 'The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway', Cancer Research, 58, pp. 5294 - 5297

Luckman SP; Coxon FP; Ebetino FH; Russell RGG; Rogers MJ, 1998, 'Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: Evidence from structure- activity relationships in J774 macrophages', Journal of Bone and Mineral Research, 13, pp. 1668 - 1678, http://dx.doi.org/10.1359/jbmr.1998.13.11.1668

Coxon FP; Benford HL; Russell RGG; Rogers MJ, 1998, 'Protein synthesis is required for caspase activation and induction of apoptosis by bisphosphonate drugs', Molecular Pharmacology, 54, pp. 631 - 638

Ebetino FH; Francis MD; Rogers MJ; Russell RGG, 1998, 'Mechanisms of action of etidronate and other bisphosphonates', Reviews in Contemporary Pharmacotherapy, 9, pp. 233 - 243

Luckman SP; Hughes DE; Coxon FP; Russell RGG; Rogers MJ, 1998, 'Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras', Journal of Bone and Mineral Research, 13, pp. 581 - 589, http://dx.doi.org/10.1359/jbmr.1998.13.4.581

Mönkkönen J; Similä J; Rogers MJ, 1998, 'Effects of tiludronate and ibandronate on the secretion of proinflammatory cytokines and nitric oxide from macrophages in vitro', Life Sciences, 62, http://dx.doi.org/10.1016/S0024-3205(97)01178-8

Shipman CM; Rogers MJ; Apperley JF; Russell RGG; Croucher PI, 1998, 'Anti-tumour activity of bisphosphonates in human myeloma cells', Leukemia and Lymphoma, 32, pp. 129 - 138, http://dx.doi.org/10.3109/10428199809059253

Auriola S; Frith J; Rogers MJ; Koivuniemi A; Mönkkönen J, 1997, 'Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography-electrospray mass spectrometry', Journal of Chromatography B: Biomedical Applications, 704, pp. 187 - 195, http://dx.doi.org/10.1016/S0378-4347(97)00490-8

Frith JC; Mönkkönen J; Blackburn GM; Russell RGG; Rogers MJ, 1997, 'Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(β,γ-dichloromethylene) triphosphate, by mammalian cells in vitro', Journal of Bone and Mineral Research, 12, pp. 1358 - 1367, http://dx.doi.org/10.1359/jbmr.1997.12.9.1358

Rogers MJ; Xiong X; Ji X; Mönkkönen J; Russell RGG; Williamson MP; Ebetino FH; Watts DJ, 1997, 'Inhibition of growth of Dictyostelium discoideum amoebae by bisphosphonate drugs is dependent on cellular uptake', Pharmaceutical Research, 14, pp. 625 - 630, http://dx.doi.org/10.1023/A:1012157212793

Shipman CM; Rogers MJ; Apperley JF; Russell RGG; Croucher PI, 1997, 'Bisphosphonates induce apoptosis in human myeloma cell lines: A novel anti-tumour activity', British Journal of Haematology, 98, pp. 665 - 672, http://dx.doi.org/10.1046/j.1365-2141.1997.2713086.x

Russell RGG; Rogers MJ, 1997, 'Introduction to bisphosphonates and the clinical pharmacology of alendronate', British Journal of Rheumatology, 36, pp. 10 - 14

Rogers MJ; Chilton KM; Luckman SP; Russell RGG; Coxon FP, 1996, 'MOLECULAR STUDIES OF APOPTOSIS INDUCED BY ANTI-RESORPTIVE BISPHOSPHONATE DRUGS', Biochemical Society Transactions, 24, pp. 568S - 568S, http://dx.doi.org/10.1042/bst024568sc

Rogers MJ; Brown RJ; Hodkin V; Blackburn GM; Russell RGG; Watts DJ, 1996, 'Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes', Biochemical and Biophysical Research Communications, 224, pp. 863 - 869, http://dx.doi.org/10.1006/bbrc.1996.1113

Rogers MJ; Chilton KM; Coxon FP; Lawry J; Smith MO; Suri S; Russell RGG, 1996, 'Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism', Journal of Bone and Mineral Research, 11, pp. 1482 - 1491, http://dx.doi.org/10.1002/jbmr.5650111015

Frith JC; Graham R; Russell G; Michael Blackburn G; Watts DJ; Rogers MJ, 1996, 'The anti-resorptive drug clodronate is metabolised to a non-hydrolysable ATP analogue by mammalian cells in vitro', Biochemical Society Transactions, 24, http://dx.doi.org/10.1042/bst024562s

Rogers MJ; Xiong X; Brown RJ; Watts DJ; Russell RGG; Bayless AV; Ebetino FH, 1995, 'Structure-activity relationships of new heterocycle-containing bisphosphonates as inhibitors of bone resorption and as inhibitors of growth of Dictyostelium discoideum amoebae', Molecular Pharmacology, 47, pp. 398 - 402

Rogers MJ; Chilton KM; Suri S; Russell RGG, 1995, 'Bisphosphonates induce apoptosis in mouse macrophage-like cells by a mechanism that does not involve changes in the level of nitric oxide or p53', Bone, 17, pp. 605 - 605, http://dx.doi.org/10.1016/8756-3282(96)87972-5

Fleming J; Rogers MJC; Brown SDM; Steel KP, 1994, 'Linkage analysis of the whirler deafness gene on mouse chromosome 4', Genomics, 21, pp. 42 - 48, http://dx.doi.org/10.1006/geno.1994.1222

Rogers MJ; Ji X; Russell GG; Blackburn GM; Williamson MP; Bayless AV; Ebetinos FH; Watts DJ, 1994, 'Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum', Biochemical Journal, 303, pp. 303 - 311, http://dx.doi.org/10.1042/bj3030303

Rogers MJ; Watts DJ; Russell RGG; Ji X; Xiong X; Blackburn GM; Bayless AV; Ebetino FH, 1994, 'Inhibitory effects of bisphosphonates on growth of amoebae of the cellular slime mold dictyostelium discoideum', Journal of Bone and Mineral Research, 9, pp. 1029 - 1039, http://dx.doi.org/10.1002/jbmr.5650090710

Xiong X; Russell RGG; Rogers MJ; Ji X; Ebetino FH; Watts DJ, 1994, 'P69. Inhibition of growth of Dictyostelium discoideum by bisphosphonates is dependent on the bisphosphonates being taken up by pinocytosis', Bone, 15, pp. 246 - 246, http://dx.doi.org/10.1016/8756-3282(94)90802-8

Brown RJ; Rogers MJ; Watts DJ; Russell RGG; Ebetino FH, 1994, 'P70. Inhibition by bisphosphonates of mammalian aminoacyl-tRNA synthetase enzymes', Bone, 15, pp. 246 - 246, http://dx.doi.org/10.1016/8756-3282(94)90803-6

Rogers MJ; Xiong X; Brown RJ; Watts DJ; Russell RGG; Ebetino FH, 1994, 'P71. The effects of bisphosphonates and their phosphinic acid analogues on bone resorption and on growth of Dictyostelium amoebae', Bone, 15, pp. 247 - 247, http://dx.doi.org/10.1016/8756-3282(94)90804-4

Rogers MJ; Russell RGG; Blackburn GM; Williamson MP; Watts DJ, 1992, 'Metabolism of halogenated bisphosphonates by the cellular slime mould dictyostelium discoideum', Biochemical and Biophysical Research Communications, 189, pp. 414 - 423, http://dx.doi.org/10.1016/0006-291X(92)91574-A

Rogers M; Watts DJ; Ji X; Russell RGG; Xiong X; Blackburn GM; Ebetino FH, 1992, 'Inhibition by bisphosphonates of growth of a wild type and resistant strain of the slime mould dictyostelium discoideum', Bone and Mineral, 17, pp. 187 - 187, http://dx.doi.org/10.1016/0169-6009(92)92086-6

Rogers M; Watts DJ; Ji X; Russell RGG; Xiong X; Blackburn GM; Ebetino FH, 1992, 'Inhibition by bisphosphonates of growth of a wild type and resistant strain of the slime mould dictyostelium discoideum', Bone and Mineral, 17, pp. S16 - S16, http://dx.doi.org/10.1016/0169-6009(92)92277-w

Rogers M; Watts DJ; Ji X; Russell RGG; Blackburn GM; Williamson MP; Ebetino FH, 1992, 'Metabolism of bisphosphonates by the slime mould dictyostelium discoideum', Bone and Mineral, 17, pp. S16 - S16, http://dx.doi.org/10.1016/0169-6009(92)92275-u

Rogers M; Watts DJ; Ji X; Russell RGG; Blackburn GM; Williamson MP; Ebetino FH, 1992, 'Metabolism of bisphosphonates by the slime mould dictyostelium discoideum', Bone and Mineral, 17, pp. 187 - 187, http://dx.doi.org/10.1016/0169-6009(92)92084-4

Rogers M; Watts D; Ji X; Russell RGG; Blackburn GM; Ebetino FH, 1992, 'P2. Growth inhibitory effects of bisphosphonates on the slime mould dictyostelinm discoideum', Bone, 13, pp. 275 - 276, http://dx.doi.org/10.1016/8756-3282(92)90221-h

Blackburn GM; Ashton PR; Guo M; Rogers M; Taylor G; Guranowski A; Watts D, 1991, 'Application of phosphonate and thiophosphate analogues of nucleotides to studies of some enzyme reactions', Heteroatom Chemistry, 2, pp. 163 - 170, http://dx.doi.org/10.1002/hc.520020118

Rogers MJ; Donovan DT; Rogers MH, 1990, 'A deductive enquiry system for a palaeontological database of museum material', Palaeontology, 33, pp. 613 - 622

Rogers MJ, 1985, 'Non-marine pelecypods from the Riversdale Group (Upper Carboniferous), Nova Scotia.', 9e congres international de stratigraphie et de geologie du Carbonifere, Washington et Champaign-Urbana, 1979. Compte rendu. Vol. 5, pp. 261 - 270

Conference Papers

McDonald M; Khoo WH; Mohanty S; Terry R; Chai R; Quinn J; Pettitt J; Xiao Y; Baldock P; Rogers M; Croucher P; Phan T; Ng PY; Pavlos N; Biro M, 2019, 'Intravital imaging of osteoclasts in vivo reveals novel osteoclast fate which may underlie the therapeutic response to Denosumab withdrawal', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY, FL, Orlando, pp. 44 - 45, presented at Annual Meeting of the American-Society-for-Bone-and Mineral Research, FL, Orlando, 20 September 2019 - 23 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000508356600130&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Rogers MJ; Junankar S; McKenna CE; Sun S; Tri GP, 2014, 'Intravital 2-photon imaging reveals tumour-associated macrophages as the cellular targets underlying the anti-tumour activity of bisphosphonates in vivo.', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY-BLACKWELL, TX, Houston, pp. S14 - S14, presented at Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, TX, Houston, 12 September 2014 - 15 September 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000356598700039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wuerger T; Roschger P; Zwettler E; Fratzl P; Rogers MJ; Klaushofer K; Rumpler M, 2012, 'Osteoclasts on bone and dentin in vitro: Mechanism of degradation and comparison of resorption behaviour', in BONE, ELSEVIER SCIENCE INC, AUSTRIA, Vienna, pp. S9 - S9, presented at International Conference on Progress in Bone and Mineral Research / Annual Autumn Conference of the Austrian-Society-for-Bone-and-Mineral-Research including a Symposium on Calcium Sensing Receptor, AUSTRIA, Vienna, 29 November 2012 - 01 December 2012, http://dx.doi.org/10.1016/j.bone.2012.08.023

Sun S; Blazewska KM; Kashemirov BA; Roelofs AJ; Coxon FP; Rogers MJ; Ebetino FH; Mckenna MJ; Mckenna CE, 2011, 'Synthesis and characterization of novel fluorescent nitrogen-containing bisphosphonate imaging probes for bone active drugs', in Phosphorus, Sulfur and Silicon and the Related Elements, pp. 970 - 971, http://dx.doi.org/10.1080/10426507.2010.526674

Shay G; Hornick M; Heys S; Weilbaecher K; Rogers M, 2011, 'Abstract LB-159: Bisphosphonates are internalised by myeloid derived suppressor cells (MDSCs) in vivo in a mouse model of breast cancer', in Cancer Research, American Association for Cancer Research (AACR), http://dx.doi.org/10.1158/1538-7445.am2011-lb-159

Thompson K; Roelofs AJ; Jauhiainen M; Mönkkönen H; Mönkkönen J; Rogers MJ, 2010, 'Activation of γΔ T cells by bisphosphonates', in Advances in Experimental Medicine and Biology, pp. 11 - 20, http://dx.doi.org/10.1007/978-1-4419-1050-9_2

Russell RGG; Xia Z; Dunford JE; Oppermann U; Kwaasi A; Hulley PA; Kavanagh KL; Triffitt JT; Lundy MW; Phipps RJ; Barnett BL; Coxon FP; Rogers MJ; Watts NB; Ebetino FH, 2007, 'Bisphosphonates: An update on mechanisms of action and how these relate to clinical efficacy', in Annals of the New York Academy of Sciences, pp. 209 - 257, http://dx.doi.org/10.1196/annals.1402.089

Thompson K; Rogers MJ, 2006, 'Alkylamines and bisphosphonates: A common mechanism for activation of γδ T-cells', in Haematologica Reports, pp. 1 - 3

Rogers MJ, 2006, 'New insights into the molecular actions of nitrogen-containing bisphosphonates', in Haematologica Reports, pp. 24 - 25

Lipton A; Berenson JR; Body JJ; Boyce BF; Bruland OS; Carducci MA; Cleeland CS; Clohisy DR; Coleman RE; Cook RJ; Guise TA; Pearse RN; Powles TJ; Rogers MJ; Roodman GD; Smith MR; Suva LJ; Vessella RL; Weilbaecher KN; King L, 2006, 'Advances in treating metastatic bone cancer: Summary statement for the First Cambridge Conference', in Clinical Cancer Research, http://dx.doi.org/10.1158/1078-0432.CCR-06-1213

Ebetino FH; Rozé CN; McKenna CE; Barnett BL; Dunford JE; Russell RGG; Mieling GE; Rogers MJ, 2005, 'Molecular interactions of nitrogen-containing bisphosphonates within farnesyl diphosphate synthase', in Journal of Organometallic Chemistry, pp. 2679 - 2687, http://dx.doi.org/10.1016/j.jorganchem.2005.03.005

Shipman CM; Rogers MJ; Vanderkerken K; Van Camp B; Russell RGG; Croucher PI, 2000, 'Bisphosphonates: Mechanisms of action in multiple myeloma', in Acta Oncologica, pp. 829 - 835, http://dx.doi.org/10.1080/028418600750063587

Rogers MJ; Gordon S; Benford HL; Coxon FP; Luckman SP; Monkkonen J; Frith JC, 2000, 'Cellular and molecular mechanisms of action of bisphosphonates', in Cancer, pp. 2961 - 2978, http://dx.doi.org/10.1002/1097-0142(20000615)88:12+<2961::aid-cncr12>3.0.co;2-l

Back to profile page