By Professor William Ledger

Journal articles

Bahathiq AO; Stewart RL; Wells M; Moore HD; Pacey AA; Ledger WL, 2002, 'Production of activins by the human endosalpinx', Journal of Clinical Endocrinology and Metabolism, 87, pp. 5283 - 5289, http://dx.doi.org/10.1210/jc.2001-011884

Muttukrishna S; Sharma S; Barlow DH; Ledger W; Groome N; Sathanandan M, 2002, 'Serum inhibins, estradiol, progesterone and FSH in surgical menopause: A demonstration of ovarian pituitary feedback loop in women', Human Reproduction, 17, pp. 2535 - 2539, http://dx.doi.org/10.1093/humrep/17.10.2535

Bahathiq A; Wells M; Ledger W, 2002, 'Activins and follistatin may participate in sperm biology and in early embryo development', JOURNAL OF PATHOLOGY, 198, pp. 19A - 19A, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000177903200076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger W, 2002, 'What to do about the polycystic ovary 'epidemic'', Current Opinion in Obstetrics and Gynecology, 14, pp. 293 - 294, http://dx.doi.org/10.1097/00001703-200206000-00008

Silverberg K; Daya S; Auray JP; Duru G; Ledger W; Wikland M; Bouzayen R; O'Brien M; Falk B; Beresniak A, 2002, 'Analysis of the cost effectiveness of recombinant versus urinary follicle-stimulating hormone in in vitro fertilization/intracytoplasmic sperm injection programs in the United States', Fertility and Sterility, 77, pp. 107 - 113, http://dx.doi.org/10.1016/S0015-0282(01)02945-4

Cheong YC; Shelton JB; Laird SM; Richmond M; Kudesia G; Li TC; Ledger WL, 2002, 'IL-1, IL-6 and TNF-α concentrations in the peritoneal fluid of women with pelvic adhesions', Human Reproduction, 17, pp. 69 - 75

Ledger WL, 2002, 'In vitro fertilization', Current Obstetrics and Gynaecology, 12, pp. 269 - 275, http://dx.doi.org/10.1016/S0957-5847(02)90274-X

Amer SAK; Gopalan V; Li TC; Ledger WL; Cooke ID, 2002, 'Long term follow-up of patients with polycystic ovarian syndrome after laparoscopic ovarian drilling: Clinical outcome', Human Reproduction, 17, pp. 2035 - 2042, http://dx.doi.org/10.1093/humrep/17.8.2035

Ledger WL, 2002, 'Patient scheduling for gonadotrophin-releasing hormone antagonist protocols', Human Fertility, 5, http://dx.doi.org/10.1080/1464727992000199801

Cheong YC; Laird SM; Shelton JB; Ledger WL; Li TC; Cooke ID, 2002, 'The correlation of adhesions and peritoneal fluid cytokine concentrations: A pilot study', Human Reproduction, 17, pp. 1039 - 1045, http://dx.doi.org/10.1093/humrep/17.4.1039

Cheong YC; Laird SM; Li TC; Shelton JB; Ledger WL; Cooke ID, 2001, 'Peritoneal healing and adhesion formation/reformation', Human Reproduction Update, 7, pp. 556 - 566, http://dx.doi.org/10.1093/humupd/7.6.556

Muttukrishna S; North RA; Morris J; Schellenberg JC; Taylor RS; Asselin J; Ledger W; Groome N; Reman C, 2001, 'Serum inhibin A and activin A are elevated prior to the onset of pre eclampsia (vol 15, pg 1640, 2001)', HUMAN REPRODUCTION, 16, pp. 2477 - 2477, http://dx.doi.org/10.1093/humrep/16.11.2477

Ledger WL, 2001, 'Assisted conception: What does the future hold?', Current Opinion in Obstetrics and Gynecology, 13, pp. 305 - 307, http://dx.doi.org/10.1097/00001703-200106000-00010

Ledger WL, 2001, 'Measurement of inhibin A and activin A in pregnancy - Possible diagnostic applications', Molecular and Cellular Endocrinology, 180, pp. 117 - 121, http://dx.doi.org/10.1016/S0303-7207(01)00512-3

Asbóth G; Price SA; Bellinger J; Ledger W; Barlow DH; López Bernal A, 2001, 'Characterization of adenylyl cyclases in cultured human granulosa cells', Reproduction, 121, pp. 217 - 228, http://dx.doi.org/10.1530/rep.0.1210217

Nasseri S; Ledger WL, 2001, 'Clomiphene citrate in the twenty-first century', Human Fertility, 4, pp. 145 - 151, http://dx.doi.org/10.1080/1464727012000199212

Daya S; Ledger W; Auray JP; Duru G; Silverberg K; Wikland M; Bouzayen R; Howles CM; Beresniak A, 2001, 'Cost-effectiveness modelling of recombinant FSH versus urinary FSH in assisted reproduction techniques in the UK', Human Reproduction, 16, pp. 2563 - 2569, http://dx.doi.org/10.1093/humrep/16.12.2563

Marcus S; Ledger W, 2001, 'Efficacy and safety of long-acting GnRH agonists in in vitro fertilization and embryo transfer', Human Fertility, 4, pp. 85 - 93, http://dx.doi.org/10.1080/1464727012000199351

Muttukrishna S; North RA; Morris J; Schellenberg JC; Taylor RS; Asselin J; Ledger W; Groome N; Redman C, 2001, 'Erratum: Serum inhibin A and activin A are elevated prior to the onset of pre eclampsia (Human Reproduction)', Human Reproduction, 16, pp. 2477, http://dx.doi.org/10.1093/humrep/16.11.2477

Muttukrishna S; North RA; Morris J; Schellenberg JC; Taylor RS; Asselin J; Ledger W; Groome N; Redman CWG, 2001, 'Erratum: Serum inhibin A and activin A are elevated prior to the onset of pre-eclampsia (Human Reproduction (2000) 15 (1640-1645))', Human Reproduction, 16, pp. 200, http://dx.doi.org/10.1093/oxfordjournals.humrep.a002025

Muttukrishna S; Farouk A; Sharma S; Evans L; Groome N; Ledger W; Sathanandan M, 2001, 'Serum activin A and follistatin in disorders of spermatogenesis in men', European Journal of Endocrinology, 144, pp. 425 - 429, http://dx.doi.org/10.1530/eje.0.1440425

Ledger W, 2001, 'Guidelines for infertility management in primary care did not improve patient care or reduce costs', Evidence-based Obstetrics & Gynecology, 3, pp. 200 - 201, http://dx.doi.org/10.1054/ebog.2001.0291

Ledger WL, 2001, 'MANUAL ON ASSISTED REPRODUCTION 2nd edition', The Obstetrician & Gynaecologist, 3, pp. 163 - 163, http://dx.doi.org/10.1576/toag.2001.3.3.163

Muttukrishna S; North RA; Morris J; Schellenberg J-C; Taylor RS; Asselin J; Ledger W; Groome N; Redman CWG, 2001, 'Serum inhibin A and activin A are elevated prior to the onset of pre-eclampsia', Human Reproduction, 16, pp. 200 - 200, http://dx.doi.org/10.1093/humrep/16.1.200

Bahatiq A; Ledger W, 2000, 'Inhibins and activins and their activity in male reproductive biology', Reproductive Medicine Review, 8, pp. 87 - 106, http://dx.doi.org/10.1017/S0962279900000168

Muttukrishna S; Child T; Lockwood GM; Groome NP; Barlow DH; Ledger WL, 2000, 'Serum concentrations of dimeric inhibins, activin A, gonadotrophins and ovarian steroids during the menstrual cycle in older women', HUMAN REPRODUCTION, 15, pp. 549 - 556, http://dx.doi.org/10.1093/humrep/15.3.549

Ledger WL, 2000, 'Could tight garments cause endometriosis?', BJOG: An International Journal of Obstetrics and Gynaecology, 107, pp. 705, http://dx.doi.org/10.1111/j.1471-0528.2000.tb13323.x

Lenton E; Soltan A; Hewitt J; Thomson A; Davies W; Ashraf N; Sharma V; Jenner L; Ledger W; McVeigh E, 2000, 'Induction of ovulation in women undergoing assisted reproductive techniques: Recombinant human FSH (follitropin alpha) versus highly purified urinary FSH (urofollitropin HP)', Human Reproduction, 15, pp. 1021 - 1027, http://dx.doi.org/10.1093/humrep/15.5.1021

Jackson N; Biddolph SC; Ledger W; Groome NP; Manek S, 2000, 'Inhibin expression in normal and pre-eclamptic placental tissue', International Journal of Gynecological Pathology, 19, pp. 219 - 224, http://dx.doi.org/10.1097/00004347-200007000-00004

Ledger WL; Skull J, 2000, 'Rationing fertility services in the NHS: A provider's perspective', Human Fertility, 3, pp. 155 - 156, http://dx.doi.org/10.1080/1464727002000198881

Muttukrishna S; North RA; Morris J; Schellenberg JC; Taylor RS; Asselin J; Ledger W; Groome N; Redman CWG, 2000, 'Serum inhibin A and activin A are elevated prior to the onset of pre-eclampsia', Human Reproduction, 15, pp. 1640 - 1645, http://dx.doi.org/10.1093/humrep/15.7.1640

Flynn ME; Ledger WL, 2000, 'The pros and cons of the oral contraceptive pill', Current Obstetrics and Gynaecology, 10, pp. 91 - 98, http://dx.doi.org/10.1054/cuog.2000.0121

Auray JP; Duru G; Daya S; Ledger W; Silverberg K; Wikland M; Bouzayen R; Howies C; Beresniak A, 2000, 'PGS2: PHARMACOECONOMIC MODELING IN ASSISTED REPRODUCTION TECHNOLOGIES: RECOMBINANT FSH VERSUS URINARY FSH', Value in Health, 3, pp. 341 - 341, http://dx.doi.org/10.1016/s1098-3015(11)70733-1

Lashen H; Ledger W; Lopez-Bernal A; Barlow D, 1999, 'Prediction of ovarian response and in-vitro fertilization outcome using age, follicle stimulating hormone (FSH), luteinizing hormone (LH), and FSH/LH ratio: a second look', HUMAN REPRODUCTION, 14, pp. 104 - 104, http://dx.doi.org/10.1093/humrep/14.Suppl_3.104

Muttukrishna S; Chamberlain P; Evans LW; Asselin J; Groome NP; Ledger WL, 1999, 'Amniotic fluid concentrations of dimeric inhibins, activin A and follistatin in pregnancy', European Journal of Endocrinology, 140, pp. 420 - 424, http://dx.doi.org/10.1530/eje.0.1400420

Ledger WL, 1999, 'Endometriosis and infertility: An integrated approach', International Journal of Gynecology and Obstetrics, 64, pp. 33 - 40, http://dx.doi.org/10.1016/s0020-7292(98)00240-9

Lau CP; Ledger WL; Groome NP; Barlow DH; Muttukrishna S, 1999, 'Dimeric inhibins and activin A in human follicular fluid and oocyte-cumulus culture medium', Human Reproduction, 14, pp. 2525 - 2530, http://dx.doi.org/10.1093/humrep/14.10.2525

Lashen H; Ledger W; Bernai AL; Barlow D, 1999, 'Extremes of body mass do not adversely affect the outcome of superovulation and in-vitro fertilization', Human Reproduction, 14, pp. 712 - 715, http://dx.doi.org/10.1093/humrep/14.3.712

Lockwood GM; Muttukrishna S; Groome NP; Ledger WL; Manek S, 1999, 'Immunohistochemical localisation of inhibin and activin subunits in normal and polycystic ovaries', JOURNAL OF PATHOLOGY, 187, pp. 29A - 29A, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000079173200116&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger W, 1999, 'Infertility, but not fertility drug use, was a risk factor for borderline ovarian cancer in nulliparous women', Evidence-based Obstetrics and Gynecology, 1, pp. 67, http://dx.doi.org/10.1054/ebog.1999.0049

Lashen H; Ledger W; Remohi J; Pellicer A, 1999, 'Management of poor responders in IVF (multiple letters) [1]', Human Reproduction, 14, pp. 1919, http://dx.doi.org/10.1093/humrep/14.7.1919

Lashen H; Ledger W; Lopez-Bernal A; Barlow D, 1999, 'Poor responders to ovulation induction: Is proceeding to in-vitro fertilization worthwhile?', Human Reproduction, 14, pp. 964 - 969, http://dx.doi.org/10.1093/humrep/14.4.964

Al-Azemi M; Ledger WL; Lockwood GM; Barlow DH, 1999, 'Successful transvaginal ultrasound-guided ablation of a cervical pregnancy in a patient with simultaneous intrauterine pregnancy after in vitro fertilization and embryo transfer', Human Fertility, 2, pp. 67 - 69, http://dx.doi.org/10.1080/1464727992000198341

Lockwood GM; Groome NP; Muttukrishna S; Ledger WL, 1998, 'Inhibin b levels are prognostic of the perimenopausal transition in women with reduced ovarian reserve and regular cycles', International Journal of Fertility and Menopausal Studies, 43, pp. 217 - 218

Lashen H; Ledger W, 1998, 'Effects of agonist dose on in-vitro fertilization', HUMAN REPRODUCTION, 13, pp. 2973 - 2973, http://dx.doi.org/10.1093/humrep/13.10.2973

Lashen H; Ledger W; Bernal AL; Evans B; Barlow D, 1998, 'Superovulation with a high gonadotropin dose for in vitro fertilization: Is it effective?', JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 15, pp. 438 - 443, http://dx.doi.org/10.1007/BF02744938

Lashen H; Ledger W; Lopez-Bernal A; Barlow D, 1998, 'Proceeding to IVF in patients producing four follicles or less: is it worthwhile?', HUMAN REPRODUCTION, 13, pp. 51 - 52, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000075359300096&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lashen H; Ledger W; Lopez-Bernal A; Barlow D, 1998, 'Total dose of gonadotrophin-releasing hormone agonist: factors affecting it and its effect on in-vitro fertilization outcome', HUMAN REPRODUCTION, 13, pp. 184 - 184, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000075359300346&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lockwood GM; Muttukrishna S; Ledger WL, 1998, 'Inhibins and activins in human ovulation, conception and pregnancy', Human Reproduction Update, 4, pp. 284 - 295, http://dx.doi.org/10.1093/humupd/4.3.284

Bagratee JS; Lockwood G; López Bernal A; Barlow DH; Ledger WL, 1998, 'Comparison of highly purified FSH (Metrodin-high purity) with pergonal for IVF superovulation', Journal of Assisted Reproduction and Genetics, 15, pp. 65 - 69, http://dx.doi.org/10.1007/BF02766827

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