By Associate Professor Nadeem Omar Kaakoush

Journal articles

Rehvathy V; Tan MH; Gunaletchumya SP; Teh X; Wang X; Baybayan P; Singh S; Ashby M; Kaakoush NO; Mitchell HM; Croft LJ; Goh KL; Loke MF; Vadivelua J, 2013, 'Multiple Genome Sequences of Helicobacter pylori Strains of Diverse Disease and Antibiotic Resistance Backgrounds from Malaysia', Genome Announcements, 1, pp. e00687-13, http://dx.doi.org/10.1128/genomeA.00687-13

Nahidi L; Leach ST; Mitchell HM; Kaakoush NO; Lemberg DA; Munday J; Huinao K; Day AS, 2013, 'Su2016 Nutritional Therapy Modulates Inflammation and Improves Altered Barrier Function in a Mouse Model of Colitis', Gastroenterology, 144, pp. S - 532, http://dx.doi.org/10.1016/s0016-5085(13)61978-2

Sirianni A; Kaakoush NO; Raftery MJ; Mitchell HM, 2013, 'The pathogenic potential of Helicobacter pullorum: Possible role for the Type VI secretion system', Helicobacter, 18, pp. 102 - 111, http://dx.doi.org/10.1111/hel.12009

Kaakoush NO; Sirianni A; Raftery MJ; Mitchell HM, 2013, 'The Secretome of Helicobacter Trogontum', Helicobacter, 18, pp. 316 - 320, http://dx.doi.org/10.1111/hel.12045

Burgos-Portugal JA; Kaakoush NO; Raftery MJ; Mitchell HM, 2012, 'Pathogenic potential of Campylobacter ureolyticus', Infection and Immunity, 80, pp. 883 - 890, http://dx.doi.org/10.1128/IAI.06031-11

Castano-Rodriguez N; Kaakoush NO; Pardo AL; Schmidt H-MA; Ha DM; Goh K-L; Fock KM; Sutton P; Forman D; Mitchell HM, 2012, 'Genetic polymorphisms involved in the toll-like receptor signaling pathway and Helicobacter pylori-related gastric cancer: a case-control study and meta-analysis', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27, pp. 11 - 11, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000298599600029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Castano-Rodriguez N; Kaakoush NO; Pardo AL; Schmidt H-MA; Ha DM; Sutton P; Goh K-L; Fock KM; Forman D; Mitchell HM, 2012, 'PAR-1 polymorphisms and risk of gastric cancer in a Chinese population', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27, pp. 11 - 11, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000298599600030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kaakoush NO; Mitchell HM, 2012, 'Campylobacter concisus - a new player in intestinal disease', Frontiers in Cellular and Infection Microbiology, 2, pp. 4 - 4, http://dx.doi.org/10.3389/fcimb.2012.00004

Gunaletchumy SP; Teh X; Khosravi Y; Chua EG; Kavitha T; Ramli NS; Mason JN; Lee HT; Alias H; Zaidan NZ; Tay LC; Rudd S; Mitchell HM; Kaakoush NO; Loke MF; Goh K-L; Vadivelu J, 2012, 'Draft genome sequences of Helicobacter pylori isolated from Malaysia, cultured from patients with functional dyspepsia and gastric cancer', Journal of Bacteriology, 194, pp. 5695 - 5696, http://www.ncbi.nlm.nih.gov/pubmed/23012278

Lavrencic P; Kaakoush NO; Huinao KD; Kain N; Mitchell HM, 2012, 'Investigation of motility and biofilm formation by intestinal Campylobacter concisus strains.', Gut Pathogens, 4, pp. 22

Kaakoush NO; Huinao KD; Leach ST; Lemberg DA; Dowd S; Mitchell HM; Day AS, 2012, 'Microbial dysbiosis in pediatric patients with Crohn's disease.', Journal of Clinical Microbiology, 50, pp. 3258 - 3266, http://dx.doi.org/10.1128/JCM.01396-12

Castano-Rodriguez N; Kaakoush NO; Schmidt HA; Goh K; Fock KM; Sutton P; Chionh Y; Mitchell HM, 2012, 'PAR-1 polymorphisms and risk of Helicobacter pylori-related gastric cancer in a Chinese population', Anticancer Research, 32, pp. 3715 - 3721, http://www.ncbi.nlm.nih.gov/pubmed/22993310

Burgos-Portugal J; Kaakoush NO; Raftery MJ; Mitchell HM, 2012, 'Pathogenic potential of Campylobacter ureolyticus', Infection and Immunity, 80, pp. 883 - 890, http://dx.doi.org/10.1128/?IAI.06031-11

Deshpande NP; Kaakoush NO; Mitchell H; Janitz K; Raftery MJ; Li SS; Wilkins MR, 2011, 'Sequencing and Validation of the Genome of a Campylobacter concisus Reveals Intra-Species Diversity', PLoS ONE, 6, pp. e22170 - e22170, http://dx.doi.org/10.1371/journal.pone.0022170

Man SM; Kaakoush NO; Mitchell HM, 2011, 'Erratum: The role of bacteria and pattern-recognition receptors in Crohn's disease (Nature Reviews Gastroenterology and Hepatology (2011) 8 (152-168) DOI:10.1038/nrgastro.2011.3)', Nature Reviews Gastroenterology and Hepatology, 8, pp. 1, http://dx.doi.org/10.1038/nrgastro.2011.56

Kaakoush N; Holmes J; Octavia S; Man S; Zhang L; Castaño-Rodríguez N; Day A; Leach S; Lemberg D; Dutt S; Stormon M; O'Loughlin E; Magoffin A; Mitchell H, 2011, 'Detection of Helicobacteraceae in Intestinal Biopsies of Children with Crohn's Disease', Gastroenterological Endoscopy, 53, pp. 99, http://dx.doi.org/10.11280/gee.53.99

Kaakoush NO; Deshpande N; Wilkins MR; Raftery MJ; Janitz K; Mitchell HM, 2011, 'Comparative analyses of Campylobacter concisusstrains reveal the genome of the reference strain BAA-1457 is not representative of the species.', Gut Pathogens, 3, pp. 15, http://dx.doi.org/10.1186/1757-4749-3-15

Every AL; Lynne S; Castano-Rodriguez N; Wei L; Helen W; Janet LKW; Agnieszka S; Barry JM; Kaakoush NO; Mitchell HM; Sutton P; Castano Rodriguez N, 2011, 'Did transmission of Helicobacter pylori from humans cause a disease outbreak in a colony of Stripe-faced Dunnarts (Sminthopsis macroura)?', Veterinary Research, 42, pp. 26, http://dx.doi.org/10.1186/1297-9716-42-26

Kovach Z; Kaakoush NO; Lamb S; Zhang L; Raftery MJ; Mitchell HM; Lamb S, 2011, 'Immunoreactive proteins of Campylobacter concisus, an emergent intestinal pathogen.', FEMS Immunology and Medical Microbiology, 63, pp. 387 - 396, http://dx.doi.org/10.1111/j.1574-695X.2011.00864.x

Mahendran V; Riordan S; Grimm M; Tran TAT; Major J; Kaakoush NO; Mitchell HM; Zhang L, 2011, 'Prevalence of Campylobacter species in adult Crohn's disease and the preferential colonization sites of Campylobacter species in the human intestine', PLoS ONE, 6, pp. 1 - 7, http://dx.doi.org/10.1371/journal.pone.0025417

Kaakoush NO; Deshpande NP; Wilkins MR; Tan C; Burgos-Portugal J; Raftery MJ; Day AS; Lemberg DA; Mitchell HM, 2011, 'The pathogenic potential of campylobacter concisus strains associated with chronic intestinal diseases', PLoS One, 6, pp. e29045, http://dx.doi.org/10.1371

Man S; Kaakoush NO; Mitchell HM, 2011, 'The role of bacteria and pattern recognition receptors in Crohn's Disease', Nature Reviews Gastroenterology and Hepatology, 8, pp. 152 - 168

Kaakoush NO; Holmes J; Octavia S; Man S; Zhang L; Castano-Rodriguez N; Day AS; Leach ST; Lemberg DA; Dutt S; Stormon M; O'Loughlin EV; Magoffin A; Mitchell HM, 2010, 'Detection of Helicobacteraceae in intestinal biopsies of children with Crohn's disease', Helicobacter, 15, pp. 549 - 557

Man S; Kaakoush NO; Leach ST; Nahidi L; Lu HK; Norman J; Day AS; Zhang L; Mitchell HM, 2010, 'Host attachment, invasion and stimulation of proinflammatory cytokines by Campylobacter concisus and other non-Campylobacter jejuni Campylobacter species', Journal of Infectious Diseases, 202, pp. 1855 - 1865

Ford JL; Kaakoush NO; Mendz GL, 2010, 'Phosphonate Metabolism in Helicobacter pylori', Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 97, pp. 51 - 60

Schmidt HM; Andres S; Nilsson C; Kovach Z; Kaakoush NO; Engstrand L; Goh K-L; Fock K; Forman D; Mitchell HM, 2010, 'The cag PAI is intact and functional but HP0521 varies significantly in Helicobacter pylori isolates from Malaysia and Singapore', European Journal of Clinical Microbiology and Infectious Diseases, 29, pp. 439 - 451

Man S; Kaakoush NO; Octavia S; Mitchell HM, 2010, 'The internal transcribed spacer region: A new tool in species differentiation and delineation of systematic relationships within the Campylobacter genus', Applied and Environmental Microbiology, 76, pp. 3071 - 3081, http://dx.doi.org/10.1128/AEM.02551-09

Kaakoush NO; Man SM; Lamb S; Raftery MJ; Wilkins MR; Kovach Z; Mitchell HM, 2010, 'The secretome of Campylobacter concisus.', FEBS Journal, 277, pp. 1606 - 1617

Kaakoush NO; Asencio C; Megraud F; Mendz GL, 2009, 'A redox basis for metronidazole resistance in helicobacter pylori', Antimicrobial Agents and Chemotherapy, 53, pp. 1884 - 1891

Hartley L; Kaakoush NO; Ford JL; Korolik V; Mendz GL, 2009, 'Characterisation of Campylobacter jejuni genes potentially involved in phosphonate degradation.', Gut Pathogens, 1, pp. 1 - 9, http://dx.doi.org/10.1186/1757-4749-1-13

Kaakoush NO; Mendz GL, 2009, 'Inhibition of disulfide reductases as a therapeutic strategy', Current Enzyme Inhibition, 5, pp. 117 - 133

Kaakoush NO; Baar C; Fox E; MacKichan J; Schuster SC; Mendz GL, 2009, 'Insights into the molecular basis of the microaerophily of three Campylobacterales: a comparative study', Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 96, pp. 545 - 557

Schmidt HA; Andras S; Kaakoush NO; Engstrand L; Eriksson L; Goh K-L; Fock KM; Hilmi I; Dhamodaran S; Forman D; Mitchell HM, 2009, 'The prevalence of the duodenal ulcer promoting gene (dupA) in Helicobacter pylori isolates varies by ethnic group and is not universally associated with disease development: a case-control study.', Gut Pathogens, 1, pp. 1 - 5

Kaakoush NO; Raftery MJ; Mendz GL, 2008, 'Molecular response of campylobacter jejuni to cadmium stress', FEBS Journal, 275, pp. 5021 - 5033

Kaakoush NO; Raftery M; Mendz GL, 2007, 'Molecular responses of Campylobacter jejuni to cadmium stress', ZOONOSES AND PUBLIC HEALTH, 54, pp. 61 - 61, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000250519200196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kaakoush NO; Sterzenbach T; Miller W; Suerbaum S; Mendz GL, 2007, 'Identification of disulfide reductases in Campylobacterales: a bioinformatics investigation', Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 92, pp. 429 - 441

Kaakoush NO; Miller W; De Reuse H; Mendz GL, 2007, 'Oxygen requirement and tolerance of Campylobacter jejuni', Research in Microbiology, 158, pp. 644 - 650

Kaakoush NO; Kovach Z; Mendz GL, 2007, 'Potential role of thiol : disulfide oxidoreductases in the pathogenesis of Helicobacter pylori', FEMS Immunology and Medical Microbiology, 50, pp. 177 - 183

Bury-Mone S; Kaakoush NO; Asencio C; Megraud F; Thibonnier M; De Reuse H; Mendz GL, 2006, 'Is Helicobacter pylori a true microaerophile?', Helicobacter, 11, pp. 296 - 303

Kaakoush NO; Mendz GL, 2005, 'Helicobacter pylori disulphide reductases: role in metronidazole reduction', FEMS Immunology and Medical Microbiology, 44, pp. 137 - 142

Conference Papers

Yin J; Kaakoush NO; Massey J; Danta M, 2025, 'Understanding the microbiome in autologous haemopoietic stem cell transplant for multiple sclerosis', in Frontiers in Immunology, http://dx.doi.org/10.3389/fimmu.2025.1590601

Wark G; Kaakoush NO; Samocha-Bonet D; Ghaly S; Danta M, 2023, 'Determinants of oral microbial diversity and relationship with the stool microbiome in patients with inflammatory bowel disease', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 104 - 104

Chetwood J; Paramsothy S; Haifer C; Leong R; Kaakoush NO, 2023, 'Key metabolomic alterations are associated with ulcerative colitis disease state and activity', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 108 - 109

Wark G; Samocha-Bonet D; Ghaly S; Kaakoush NO; Danta M, 2023, 'Vitamin D as a biomarker of disease activity and metabolic health in inflammatory bowel disease', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 129 - 130

Luu LDW; Popple G; Tsang SPW; Vinasco K; Hilmi I; Ng RT; Chew KS; Wong SY; Riordan S; Lee WS; Mitchell HM; Kaakoush NO; Castaño-Rodríguez N, 2022, 'Genetic variants involved in innate immunity modulate the risk of inflammatory bowel diseases in an understudied Malaysian population', in Journal of Gastroenterology and Hepatology Australia, pp. 342 - 351, http://dx.doi.org/10.1111/jgh.15752

Vinasco-Pacheco K; Mitchell H; Kaakoush N; Castano-Rodriguez N; Castano Rodriguez N, 2020, 'The role of lactate in gastric carcinogenesis', in HELICOBACTER, WILEY, ELECTR NETWORK, pp. 56 - 57, presented at 33rd International Workshop on Helicobacter and Microbiota in Inflammation and Cancer, ELECTR NETWORK, 12 September 2020, http://dx.doi.org/10.26190/unsworks/28160

Rodriguez NC; Goswami AB; Simovic I; Mitchell HM; Kaakoush NO; Fock KM; Goh KL; Porras-Hurtado GL; Cardona-Deazza JL; Montoya-Martinez JJ; Cadavid-Velez AJ; Toro-Hidalgo HW; Cobo-Alvarado AR; Hincapie-Rincon ODS, 2019, 'UNDERSTANDING THE TUMOUR-PROMOTING FUNCTIONS OF AUTOPHAGY IN GASTRIC CARCINOGENESIS', in HELICOBACTER, WILEY, AUSTRIA, Innsbruck, presented at 32nd International Workshop on Helicobacter and Microbiota in Inflammation and Cancer (EHMSG), AUSTRIA, Innsbruck, 05 September 2019 - 07 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000486077700035&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ong KL; Hui N; Januszewski AS; Kaakoush NO; Xu A; Fayyad R; DeMicco DA; Jenkins AJ; Keech AC; Waters DD; Barter PJ; Rye K-A, 2018, 'Relationship of FGF21 Levels With Major Cardiovascular Events in Patients Treated With Atorvastatin (From the Treating to New Targets [TNT] Study).', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS

Paramsothy S; Kamm MA; Nielsen S; Deshpande N; Faith J; Clemente JC; Paramsothy R; Walsh A; van den Bogaerde J; Samuel D; Leong RW; Connor SJ; Ng WSW; Lin E; Wilkins M; Colombel JF; Borody TJ; Mitchell HM; Kaakoush NO, 2018, 'IN FECAL MICROBIOTA TRANSPLANTATION (FMT) FOR ULCERATIVE COLITIS, FUSOBACTERIUM IS ASSOCIATED WITH LACK OF REMISSION, WHILE METABOLIC SHIFTS TO STARCH DEGRADATION AND SHORT CHAIN FATTY ACID PRODUCTION ARE ASSOCIATED WITH REMISSION - RESULTS FROM THE RANDOMIZED CONTROLLED FOCUS STUDY', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. S35 - S35, presented at Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week, DC, Washington, 02 June 2018 - 05 June 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000450011100099&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kaakoush NO; Lecomte V; Maloney CA; Morris MJ, 2017, 'Chronic exposure to an obesogenic diet alters host gene expression and microbiome in the esophagus', in HELICOBACTER, WILEY, FRANCE, Bordeaux, presented at 30th International Workshop of the European-Helicobacter-and-Microbiota-Study-Group (EHMSG) on Helicobacter and Microbiota in Inflammation and Cancer, FRANCE, Bordeaux, 07 September 2017 - 09 September 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000423287200347&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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