Select Publications

Book Chapters

Iismaa SE, 2016, 'Insights into transglutaminase 2 function gained from genetically modified animal models', in Transglutaminases: Multiple Functional Modifiers and Targets for New Drug Discovery, Springer, pp. 83 - 115,

Nanda N; Iismaa SE, 2002, 'Transglutaminases', in John Wiley & Sons Inc. (ed.), Wiley Encyclopedia of Molecular Medicine, Volumes 1-5, edn. Original, John Wiley & Sons, pp. 3222 - 3224

Graham RM; Riek RP; Iismaa S; Chen S, 1995, 'Adrenergic and dopamine receptors', in Molecular Nephrology, edn. Original, Marcel Dekker, New York, pp. 143 - 155

Journal articles

McGrath-Cadell L; Hesselson S; Tarr I; Iismaa SE; Bax M; Junday K; Dunwoodie SE; Fatkin D; Kovacic J; Muller DWM; Giannoulatou E; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection (SCAD) and a family history of aortic artery dissection, a case series', European Heart Journal, vol. 42,

Naqvi N; Iismaa SE; Graham RM; Husain A, 2021, 'Mechanism-Based Cardiac Regeneration Strategies in Mammals', Frontiers in Cell and Developmental Biology, vol. 9, pp. 747842,

Kaidonis X; Niu W; Chan AY; Kesteven S; Wu J; Iismaa SE; Vatner S; Feneley M; Graham RM, 2021, 'Adaptation to exercise-induced stress is not dependent on cardiomyocyte α1A-adrenergic receptors', Journal of Molecular and Cellular Cardiology, vol. 155, pp. 78 - 87,

Guo Y; Yu ZY; Wu J; Gong H; Kesteven S; Iismaa SE; Chan AY; Holman S; Pinto S; Pironet A; Cox CD; Graham RM; Vennekens R; Feneley MP; Martinac B, 2021, 'The ca2+-activated cation channel trpm4 is a positive regulator of pressure overload-induced cardiac hypertrophy', eLife, vol. 10,

Iismaa SE; Hesselson S; McGrath-Cadell L; Muller DW; Fatkin D; Giannoulatou E; Kovacic J; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women', Heart Lung and Circulation, vol. 30, pp. 27 - 35,

Bax M; Junday K; Hesselson S; Iismaa S; Tarr I; McGrath-Cadell L; Dunwoodie S; Fatkin D; Kovacic J; Muller D; Giannoulatou E; Graham R, 2021, 'Modelling Spontaneous Coronary Artery Dissection With iPSC-Derived Vascular Cells', Heart, Lung and Circulation, vol. 30, pp. S131 - S131,

McGrath-Cadell L; Iismaa SE; Hesselson S; Muller DW; Fatkin D; Giannoulatou E; Kovacic JC; Graham RM, 2021, 'Recent Updates on Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia', International Journal of Integrative Cardiology, vol. 3,

McGrath-Cadell L; Hesselson S; Tarr I; Iismaa S; Bax M; Junday K; Dunwoodie S; Fatkin D; Kovacic J; Muller D; Giannoulatou E; Graham B, 2021, 'Spontaneous Coronary Artery Dissection (SCAD) and a Family History of Aortic Artery Dissection—A Case Series', Heart, Lung and Circulation, vol. 30, pp. S252 - S252,

Griffin KJ; Simpson KR; Beckers CML; Newell LM; Cheah LT; Yuldasheva NY; Iismaa S; Jackson CL; Scott JDA; Pease RJ, 2021, 'Transglutaminase 2 moderates the expansion of mouse abdominal aortic aneurysms.', JVS Vasc Sci, vol. 2, pp. 95 - 109,

Bogush N; Tan L; Naib H; Faizullabhoy E; Calvert JW; Iismaa SE; Gupta A; Ramchandran R; Martin DIK; Graham RM; Husain A; Naqvi N, 2020, 'DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling', Scientific Reports, vol. 10, pp. 21918,

Nicks AM; Kesteven SH; Li M; Wu J; Chan AY; Naqvi N; Husain A; Feneley MP; Smith NJ; Iismaa SE; Graham RM, 2020, 'Pressure overload by suprarenal aortic constriction in mice leads to left ventricular hypertrophy without c-Kit expression in cardiomyocytes', Scientific Reports, vol. 10, pp. 15318,

Zhang J; Grosso Jasutkar H; Yan R; Woo JM; Lee KW; Im JY; Junn E; Iismaa SE; Mouradian MM, 2020, 'Transglutaminase 2 Depletion Attenuates α-Synuclein Mediated Toxicity in Mice', Neuroscience, vol. 441, pp. 58 - 64,

Suzuki AS; Yagi R; Kimura MY; Iwamura C; Shinoda K; Onodera A; Hirahara K; Tumes DJ; Koyama-Nasu R; Iismaa SE; Graham RM; Motohashi S; Nakayama T, 2020, 'Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation', Frontiers in Immunology, vol. 11,

Griffin KJ; Newell LM; Simpson KR; Beckers CML; Drinkhill MJ; Standeven KF; Cheah LT; Iismaa SE; Grant PJ; Jackson CL; Pease RJ, 2020, 'Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency', Atherosclerosis, vol. 294, pp. 1 - 9,

Carss KJ; Baranowska AA; Armisen J; Webb TR; Hamby SE; Premawardhana D; Al-Hussaini A; Wood A; Wang Q; Deevi SVV; Vitsios D; Lewis SH; Kotecha D; Bouatia-Naji N; Hesselson S; Iismaa SE; Tarr I; McGrath-Cadell L; Muller DW; Dunwoodie SL; Fatkin D; Graham RM; Giannoulatou E; Samani NJ; Petrovski S; Haefliger C; Adlam D, 2020, 'Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation from Genome Sequencing', Circulation: Genomic and Precision Medicine, pp. 630 - 639,

Mishra K; Junday K; Wong CMY; Chan AY; Hesselson S; Muller DW; Iismaa SE; Mehta A; Graham RM, 2019, 'Generation of VCCRIi001-A, a human induced pluripotent stem cell line, from a patient with spontaneous coronary artery dissection', Stem Cell Research, vol. 41, pp. 101584 - 101584,

McGrath-Cadell L; Hesselson S; Iismaa SE; Mishra K; Wong CMY; Fatkin D; Dunwoodie SL; Harvey R; Holloway CJ; Muller DWM; Giannoulatou E; Graham RM, 2019, 'P5540Familial clustering of spontaneous coronary artery dissection', European Heart Journal, vol. 40,

Kaidonis X; Niu W; Chan AY; Kesteven S; Wu J; Iismaa SE; Feneley M; Graham RM, 2019, 'Abstract 579: Involvement of the Alpha 1A-Adrenergic Receptor in the Cardiac Adaptation to Physiological Stress', Circulation Research, vol. 125,

Lorand L; Iismaa SE, 2019, 'Correction to: Transglutaminase diseases: from biochemistry to the bedside (The FASEB Journal, (2019), 33, 1, (3-12), 10.1096/fj.201801544R)', FASEB Journal, vol. 33, pp. 4653,

Adlam D; Olson TM; Combaret N; Kovacic JC; Iismaa SE; Al-Hussaini A; O'Byrne MM; Bouajila S; Georges A; Mishra K; Braund PS; d'Escamard V; Huang S; Margaritis M; Nelson CP; de Andrade M; Kadian-Dodov D; Welch CA; Mazurkiewicz S; Jeunemaitre X; Motreff P; Belle L; Dupouy P; Barnay P; Meneveau N; Gilard M; Rioufol G; Range G; Brunel P; Delarche N; Filippi E; Le Bivic L; Harbaoui B; Benamer H; Cayla G; Varenne O; Manzo-Silberman SP; Silvain J; Spaulding C; Caussin C; Gerbaud E; Valy Y; Koning R; Lhermusier T; Champin S; Salengro E; Fluttaz A; Zabalawi A; Cottin Y; Teiger E; Saint-Etienne C; Ducrocq G; Marliere S; Boiffard E; Aubry P; Georges JL; Bresson D; De Poli F; Karrillon G; Roule V; Bali L; Valla M; Gerbay A; Houpe D; Dubreuil O; Monnier A; Mayaud N; Manchuelle A; Commeau P; Bedossa M; Wong CMY; Giannoulatou E; Sweeting M; Muller D; Wood A; McGrath-Cadell L; Fatkin D; Dunwoodie SL; Harvey R; Holloway C; Empana JP; Jouven X; Nikpay M; Goel A; Won HH; Hall LM; Willenborg C; Kanoni S; Saleheen D; Kyriakou T; Hopewell JC; Webb TR; Zeng L; Dehghan A; Alver M; Armasu SM; Auro K; Bjonnes A; Chasman DI; Chen S, 2019, 'Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection', Journal of the American College of Cardiology, vol. 73, pp. 58 - 66,

Poole LG; Pant A; Baker KS; Kopec AK; Cline-Fedewa HM; Iismaa SE; Flick MJ; Luyendyk JP, 2019, 'Chronic liver injury drives non-traditional intrahepatic fibrin(ogen) crosslinking via tissue transglutaminase', Journal of Thrombosis and Haemostasis, vol. 17, pp. 113 - 125,

Lorand L; Iismaa SE, 2019, 'Transglutaminase diseases: From biochemistry to the bedside', FASEB Journal, vol. 33, pp. 3 - 12,

McGrath-Cadell L; Hesselson S; Iismaa S; Mishra K; Wong C; Fatkin D; Dunwoodie S; Harvey R; Holloway C; Muller D; Giannoulatou E; Graham R, 2019, 'Familial Clustering of Spontaneous Coronary Artery Dissection', Heart, Lung and Circulation, vol. 28, pp. S330 - S330,

Iismaa SE; Li M; Kesteven S; Wu J; Chan AY; Holman SR; Calvert JW; Haq AU; Nicks AM; Naqvi N; Husain A; Feneley MP; Graham RM, 2018, 'Cardiac hypertrophy limits infarct expansion after myocardial infarction in mice', Scientific Reports, vol. 8,

Iismaa SE; Kaidonis X; Nicks AM; Bogush N; Kikuchi K; Naqvi N; Harvey RP; Husain A; Graham RM, 2018, 'Comparative regenerative mechanisms across different mammalian tissues', npj Regenerative Medicine, vol. 3,

Mižíková I; Pfeffer T; Nardiello C; Surate Solaligue DE; Steenbock H; Tatsukawa H; Silva DM; Vadász I; Herold S; Pease RJ; Iismaa SE; Hitomi K; Seeger W; Brinckmann J; Morty RE, 2018, 'Targeting transglutaminase 2 partially restores extracellular matrix structure but not alveolar architecture in experimental bronchopulmonary dysplasia', FEBS Journal, vol. 285, pp. 3056 - 3076,

Coleman JLJ; Mouat MA; Wu J; Jancovski N; Bassi JK; Chan AY; Humphreys DT; Mrad N; Yu ZY; Ngo T; Iismaa S; Dos Remedios CG; Feneley MP; Allen AM; Graham RM; Smith NJ, 2018, 'Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control', Biology of Sex Differences, vol. 9,

Iismaa SE, 2016, 'The prostate-specific protein, transglutaminase 4 (TG4), is an autoantigen associated with male subfertility', Annals of Translational Medicine, vol. 4,

Naqvi N; Singh R; Iismaa SE; Li M; Calvert JW; Martin DIK; Harvey RP; Graham RM; Husain A, 2015, 'Cardiomyocytes Replicate and their Numbers Increase in Young Hearts', Cell, vol. 163, pp. 783 - 784,

Cannon L; Yu ZY; Marciniec T; Waardenberg AJ; Iismaa SE; Nikolova-Krstevski V; Neist E; Ohanian M; Qiu MR; Rainer S; Harvey RP; Feneley MP; Graham RM; Fatkin D, 2015, 'Irreversible triggers for hypertrophic cardiomyopathy are established in the early postnatal period', Journal of the American College of Cardiology, vol. 65, pp. 560 - 569,

Li M; Iismaa SE; Naqvi N; Nicks A; Husain A; Graham RM, 2014, 'Thyroid hormone action in postnatal heart development', Stem Cell Research, vol. 13, pp. 582 - 591,

Yu ZY; Tan JC; McMahon AC; Iismaa SE; Xiao H; Kesteven SH; Reichelt ME; Mohl MC; Smith NJ; Fatkin D; Allen D; Head SI; Graham RM; Feneley MP, 2014, 'RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility', PLoS ONE, vol. 9,

Naqvi N; Li M; Calvert JW; Tejada T; Lambert JP; Wu J; Kesteven SH; Holman SR; Matsuda T; Lovelock JD; Howard WW; Iismaa SE; Chan AY; Crawford BH; Wagner MB; Martin DIK; Lefer DJ; Graham RM; Husain A, 2014, 'A proliferative burst during preadolescence establishes the final cardiomyocyte number', Cell, vol. 157, pp. 795 - 807,

Lismaa SE; Aplin M; Holman S; Yiu T; Jackson K; Burchfield JG; Mitchell CJ; O'Reilly L; Davenport A; Cantley J; Schmitz-Peiffer C; Biden TJ; Cooney GJ; Graham RM, 2013, 'Glucose Homeostasis in Mice Is Transglutaminase 2 Independent', PLoS One, vol. 8, pp. Article numbere63346,

Tong L; Png E; AiHua H; Yong SS; Yeo HL; Riau A; Mendoz E; Charausia SS; Lim CT; Yiu TW; Iismaa SE, 2013, 'Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion', Biochimica et Biophysica ACTA - Molecular Cell Research, vol. 1833, pp. 1304 - 1315,

Yu Z; Tan J; McMahon A; Iismaa S; Xiao X; Kesteven S; Reichelt M; Mohl M; Dai Y; Sketchley A; Yang L; Gong H; Fatkin D; Allen D; Head S; Graham R; Feneley M, 2013, 'Studies of a Mouse Model of Cardiac α1A-Adrenergic Receptor Overexpression Provide Evidence For a Critical Role of RhoA/ROCK Signalling in Cardiac Contractility', Heart, Lung and Circulation, vol. 22, pp. S59 - S59,

Iismaa SE; Aplin M; Yiu T-W; Wu J; Du X-J; Graham RM, 2012, '877 TransglutaminAse 2 is cardioprotective following MyoCardal INFARCTION, but plays no role in cardiac hyPERtrophy', Journal of Hypertension, vol. 30, pp. e256 - e256,

Zhao X; Park J; Ho D; Gao S; Yan L; Ge H; Iismaa S; Lin L; Tian B; Vatner DE; Graham RM; Vatner SF, 2012, 'Cardiomyocyte overexpression of the á 1A-adrenergic receptor in the rat phenocopies second but not first window preconditioning', American Journal of Physiology - Heart and Circulatory Physiology, vol. 302, pp. H1614 - H1624,

Liu T, 2012, 'Enhancing the anticancer effect of the histone deacetylase inhibitor by activating transglutaminase', European Journal of Cancer, vol. 48, pp. 3278 - 3287,

Iismaa SE; Basso M; Berlin J; Xia L; Sleiman SF; Kuo T; Haskew-Layton R; Kim E; Antonyak MA; Cerione RA; Willis D; Cho S, 2012, 'Transglutaminase 2 Inhibition Protects against Oxidative Stress-Induced Neuronal Death Downstream of Pathological ERK Activation', Journal of Neuroscience, vol. 32, pp. 11157 - 11157,

Basso M; Berlin J; Xia L; Sleiman SF; Ko B; Haskew-Layton R; Kim E; Antonyak MA; Cerione RA; Iismaa SE; Willis D; Cho S; Ratan R, 2012, 'Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation', Journal of Neuroscience, vol. 32, pp. 6561 - 6569,

Fatkin D; Mohl M; Iismaa SE; Xiao XH; Friedrich O; Wagner ; Nikolova-Krstevski ; Wu J; Yu ZY; Feneley MP; Allen ; Graham RM, 2011, 'Regulation of murine cardiac contractility by activation of alpha(1A)-adrenergic receptor-operated Ca(2+) entry', Cardiovascular Research, vol. 91, pp. 310 - 319,

Wouters MA; Iismaa S; Fan SW; Haworth NL; Haworth , 2011, 'Thiol-based redox signalling: Rust never sleeps', International Journal of Biochemistry and Cell Biology, vol. 43, pp. 1079 - 1085,

Olsen K; Iismaa SE; Sapinoro R; Kottman RM; Kulkarni AA; Johnson G, 2011, 'Transglutaminase 2 and its role in pulmonary fibrosis', American Journal of Respiratory and Critical Care Medicine, vol. 184, pp. 699 - 707,

Mohl M; Xiao X-H; Prosser H; Iismaa S; Feneley M; Graham R, 2010, 'Involvement of a Novel a1A-Adrenergic Receptor-Coupled Signaling Pathway in Cardiac Contractility', FASEB JOURNAL, vol. 24,

Zhao X; Vatner DE; Park M; Yan L; IIsmaa S; Graham R; Vatner SF, 2010, 'Transgenic Rats with Cardiac Overexpression of alpha1A Adrenergic Receptors are protected from Myocardial Ischemia by a Nitric Oxide Mechanism', FASEB JOURNAL, vol. 24,

McConoughey S; Basso SJ; Nietsetskaya Z; Sleiman SF; Smirnova T; Langley B; Mahishi L; Cooper AJ; Antonyak MA; Cerione RA; Li B; Starkov A; Chaturvedi R; Beale M; Coppola G; Geschwind D; Ryu H; Li XR; Iismaa SE; Pallos J; Pasternack R; Hils M; Fan J; Raymond LA; Marsh JL; Thompson LM; Ratan R, 2010, 'Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease', EMBO Journal, vol. 2, pp. 349 - 370,

Back to profile page