Select Publications
Conference Abstracts
, 2017, 'COMBINATION OF SYNTHETIC RETINOID FENRETINIDE WITH RECEPTOR TYROSINE KINASE INHIBITOR PONATINIB AS A POTENTIAL NEW APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, Vol. 19, pp. 5 - 6, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402766800022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2017, 'Pilot study of a comprehensive precision medicine platform for children with high-risk cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 35, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.10539
, 2017, 'DIPG-02. RADIOSENSITIVITY OF DIPG CELLS IS ENHANCED BY TARGETING GLUCOSE METABOLISM IN VITRO AND IN VIVO', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv5, http://dx.doi.org/10.1093/neuonc/nox083.017
, 2017, 'DIPG-04. COMBINED TARGETING OF CALCIUM SIGNALLING AND RTK/PI3K PATHWAY IS A NOVEL THERAPEUTIC APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv5, http://dx.doi.org/10.1093/neuonc/nox083.019
, 2017, 'DIPG-05. COMBINATION OF SYNTHETIC RETINOID FENRETINIDE WITH RECEPTOR TYROSINE KINASE INHIBITOR PONATINIB AS A POTENTIAL NEW APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.020
, 2017, 'DIPG-07. INDUCING DNA LETHALITY THROUGH POLO-LIKE KINASE 1 INHIBITION: A NOVEL THERAPEUTIC APPROACH IN DIPG', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv6 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.022
, 2017, 'DIPG-09. TRX-E-009-1 IS A NOVEL AND A POTENT THERAPEUTIC AGENT FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv6 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.024
, 2017, 'TRTH-05. PREDICTORS OF SUCCESS OF PHASE 2 PAEDIATRIC ONCOLOGY CLINICAL TRIALS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv52 - iv52, http://dx.doi.org/10.1093/neuonc/nox083.217
, 2016, 'Outcomes of Bereaved Parents Whose Child Did or Did not Participate in An Early Phase Clinical Trial', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, Vol. 63, pp. S62 - S62, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384818800579&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2016, 'Treatment Decision Making for Young People with Cancer and Their Parents', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, Vol. 63, pp. S232 - S232, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384818801393&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2016, 'HG-04DICHLOROACETATE AND METFORMIN COMBINE TO MODULATE GLUCOSE METABOLISM AND POTENTLY SENSITISE DIPG CELLS TO RADIATION THERAPY', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii48.3 - iii48, http://dx.doi.org/10.1093/neuonc/now073.03
, 2016, 'HG-19COMBINED TARGETING OF MITOCHONDRIAL FUNCTION AND mTOR IS A POTENT NOVEL THERAPEUTIC APPROACH FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii51.3 - iii51, http://dx.doi.org/10.1093/neuonc/now073.16
, 2016, 'HG-20COMBINATION OF EPIGENETIC MODIFIERS CBL0137 AND PANOBINOSTAT IS HIGHLY POTENT IN VITRO AND IN VIVO FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-oncology, Vol. 18, pp. iii51 - iii51
, 2016, 'HG-25FENRETINIDE TARGETS THE RTK-PI3K PATHWAY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii52.5 - iii53, http://dx.doi.org/10.1093/neuonc/now073.22
, 2015, 'BT-09 * TRILEXIUM INHIBITS THE EXPRESSION OF t-NOX AND IS A NOVEL, POTENTIALLY POTENT THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 17, pp. iii5 - iii5, http://dx.doi.org/10.1093/neuonc/nov061.19
, 2015, 'HG-16 * THE ANTI-APOPTOTIC PROTEIN ARC IS OVER-EXPRESSED IN MALIGNANT GLIOMA AND CORRELATES WITH PATIENT OUTCOME', in Neuro-Oncology, Oxford University Press (OUP), Vol. 17, pp. iii14 - iii14, http://dx.doi.org/10.1093/neuonc/nov061.53
, 2015, 'The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-1611
, 2013, 'beta III-tubulin in glioblastoma: An emerging multifactorial survival factor role in chemotherapy response and tumor formation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, Vol. 73, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3431
, 2012, 'beta III-TUBULIN AND GLIOBLASTOMA: ROLE IN DRUG RESISTANCE AND TUMOURIGENESIS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 8, pp. 303 - 304, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310544400264&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Preprints
, 2025, Single-cell RNA-sequencing of cerebral spinal fluid identifies circulating tumour cells in children with brain cancer, http://dx.doi.org/10.64898/2025.12.18.694991
, 2025, Beyond Base Camp: Promise and Pitfalls of PI3K/mTOR Inhibition in Pediatric High- Grade Gliomas., http://dx.doi.org/10.21203/rs.3.rs-6508597/v1
, 2025, Expanding the utility of transcriptome analysis for mutation detection in high-risk childhood precision oncology, http://dx.doi.org/10.1101/2025.06.25.661445
, 2024, RNA N6-Methyladenosine (m6A) regulates the cell cycle in Diffuse Midline Glioma (DMG) and confers sensitivity to FTO inhibition, http://dx.doi.org/10.21203/rs.3.rs-5390888/v1
, 2024, Policy and process for returning raw genomic data to parents and young adult participants in a pediatric cancer precision medicine trial., http://dx.doi.org/10.21203/rs.3.rs-4356870/v1
, 2024, Chromatin remodeling with combined FACT and BET inhibition disrupts oncogenic transcription in Diffuse Midline Glioma, http://dx.doi.org/10.1101/2024.06.06.597703
, 2024, Integrated germline and somatic molecular profiling to detect cancer predisposition has a high clinical impact in poor-prognosis paediatric cancer, http://dx.doi.org/10.1101/2024.08.08.24311493
, 2023, Communicating with families of young people with hard-to-treat cancers: Healthcare professionals’ perspectives on challenges, skills, and training, http://dx.doi.org/10.22541/au.168438965.52340962/v1
, 2023, PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma, http://dx.doi.org/10.1101/2023.04.17.537256
, 2023, Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across pediatric and AYA sarcomas, http://dx.doi.org/10.1101/2023.07.19.548825
, 2023, Precision-guided treatment improves outcomes for children with high-risk cancers, http://dx.doi.org/10.21203/rs.3.rs-3376668/v1
, 2022, The Children’s Brain Tumor Network (CBTN) - Accelerating Research in Pediatric Central Nervous System Tumors through Collaboration and Open Science, http://dx.doi.org/10.1101/2022.10.14.511975
, 2022, A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer, http://dx.doi.org/10.1101/2022.09.16.508179
, 2022, Copper chelation inhibits TGF-βpathways and suppresses epithelial-mesenchymal transition in cancer, http://dx.doi.org/10.1101/2022.10.03.510707
, 2022, GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma, http://dx.doi.org/10.1101/2022.05.01.490250
, 2021, Mutation and Microsatellite Burden Predict Response to PD-1 Inhibition in Children with Germline DNA Replication Repair Deficiency, http://dx.doi.org/10.21203/rs.3.rs-155292/v1
, 2020, Clinical phenotypes and prognostic features of ETMRs (Embryonal Tumor with Multi-layered Rosettes) a new CNS tumor entity: A Rare Brain Tumor Registry study, http://dx.doi.org/10.1101/2020.08.12.20171801
, 2017, The Development of Delta: Using Agile to Develop a Decision Aid for Pediatric Oncology Clinical Trial Enrollment (Preprint), http://dx.doi.org/10.2196/preprints.9258
, Examining Health-Related Quality of Life in Pediatric Cancer Patients with Febrile Neutropenia: Factors Predicting for Poor Recovery in Children and the Parents, http://dx.doi.org/10.2139/ssrn.3860325
Other
, 2025, Correction to: Returning raw genomic data to research participants in a pediatric cancer precision medicine trial (npj Genomic Medicine, (2025), 10, 1, (12), 10.1038/s41525-025-00470-y), http://dx.doi.org/10.1038/s41525-025-00486-4
, 2025, Zero Childhood Cancer: a national approach to improving outcomes of Australian children with cancer through multiomic precision medicine, Elsevier BV, http://dx.doi.org/10.1016/j.pathol.2024.12.099
, 2023, Data from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.c.6960487.v1
, 2023, Data from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.c.6960487
, 2023, Supplementary Figure 1 from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.24710152.v1
, 2023, Supplementary Figure 1 from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.24710152
, 2023, Supplementary Figure 2 from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.24710149
, 2023, Supplementary Figure 2 from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.24710149.v1
, 2023, Supplementary Figure 3 from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.24710146
, 2023, Supplementary Figure 3 from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.24710146.v1
, 2023, Supplementary Figure 4 from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.24710143
, 2023, Supplementary Figure 4 from Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas, http://dx.doi.org/10.1158/1535-7163.24710143.v1