By Professor Peter Gunning

Journal articles

Ng SY; Gunning P; Eddy R; Ponte P; Leavitt J; Shows T; Kedes L, 1985, 'Evolution of the functional human β-actin gene and its multi-pseudogene family: conservation of noncoding regions and chromosomal dispersion of pseudogenes', Molecular and Cellular Biology, 5, pp. 2720 - 2732, http://dx.doi.org/10.1128/mcb.5.10.2720

Garrison JC; Hardeman E; Wade R; Kedes L; Gunning P, 1985, 'Isolation of full-length cDNAs encoding abundant adult human skeletal muscle mRNAs', Gene, 38, pp. 177 - 188, http://dx.doi.org/10.1016/0378-1119(85)90216-1

Gunning P; Mohun T; Ng SY; Ponte P; Kedes L, 1984, 'Evolution of the human sarcomeric-actin genes: Evidence for units of selection within the 3′ untranslated regions of the mRNAs', Journal of Molecular Evolution, 20, pp. 202 - 214, http://dx.doi.org/10.1007/BF02104727

Ponte P; Ng SY; Engel J; Gunning P; Kedes L, 1984, 'Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA', Nucleic Acids Research, 12, pp. 1687 - 1696, http://dx.doi.org/10.1093/nar/12.3.1687

Scheffer JW; Howe N; Gunning PW; Austin L, 1984, 'Axoplasmic Transport of Transfer RNA in the Chick Optic System', Journal of Neurochemistry, 42, pp. 698 - 704, http://dx.doi.org/10.1111/j.1471-4159.1984.tb02739.x

Gunning P; Ponte P; Kedes L; Eddy R; Shows T, 1984, 'Chromosomal location of the co-expressed human skeletal and cardiac actin genes', Proceedings of the National Academy of Sciences of the United States of America, 81, pp. 1813 - 1817, http://dx.doi.org/10.1073/pnas.81.6.1813

Gunning P; Ponte P; Kedes L; Hickey RJ; Skoultchi AI, 1984, 'Expression of human cardiac actin in mouse L cells: A sarcomeric actin associates with a nonmuscle cytoskeleton', Cell, 36, pp. 709 - 715, http://dx.doi.org/10.1016/0092-8674(84)90351-9

Leavitt J; Gunning P; Porreca P; Lin CS; Kedes L, 1984, 'Molecular cloning and characterization of mutant and wild-type human β-actin genes', Molecular and Cellular Biology, 4, pp. 1961 - 1969, http://dx.doi.org/10.1128/MCB.4.10.1961

SHOWS T; EDDY RL; HALEY L; BYERS M; HENRY M; GUNNING P; PONTE P; KEDES L, 1984, 'THE COEXPRESSED GENES FOR HUMAN ALPHA (ACTA) AND CARDIAC ACTIN (ACTC) ARE ON CHROMOSOME-1 AND CHROMOSOME-15, RESPECTIVELY', CYTOGENETICS AND CELL GENETICS, 37, pp. 583 - 583, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984RV30800269&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

CHIU CP; HARDEMAN EC; GUNNING P; BLAU HM, 1984, 'TRANSCRIPTIONAL ACTIVATION OF SARCOMERIC ACTINS IN MUSCLE X NONMUSCLE HETEROKARYONS', JOURNAL OF CELL BIOLOGY, 99, pp. A346 - A346, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984TM94901278&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Young AP; Gunning PW; Landreth GE; Ignatius M; Shooter EM, 1983, 'The nerve growth factor induced differentiation of a pheochromocytoma PC12 cell line', Birth Defects Original Article Series, 19, pp. 33 - 46

Ponte P; Gunning P; Blau H; Kedes L, 1983, 'Human actin genes are single copy for α-skeletal and α-cardiac actin but multicopy for β- and γ-cytoskeletal genes: 3' Untranslated regions are isotype specific but are conserved in evolution', Molecular and Cellular Biology, 3, pp. 1783 - 1791, http://dx.doi.org/10.1128/mcb.3.10.1783

Gunning P; Ponte P; Okayama H; Engel J; Blau H; Kedes L, 1983, 'Isolation and characterization of full-length cDNA clones for human α, β, and γ-actin mRNAs: Skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed', Molecular and Cellular Biology, 3, pp. 787 - 795, http://dx.doi.org/10.1128/MCB.3.5.787

PONTE P; GUNNING P; ENGEL J; BLAU H; KEDES L, 1983, 'MESSENGER-RNAS FOR THE SINGLE COPY HUMAN SARCOMERIC ALPHA-ACTIN AND CARDIAC-ACTIN GENES, AND FOR THE MULTIPLE COPY CYTOSKELETAL BETA-ACTIN AND GAMMA-ACTIN GENES - 3' - UNTRANSLATED REGIONS ARE NONHOMOLOGOUS BUT ARE CONSERVED IN EVOLUTION', FEDERATION PROCEEDINGS, 42, pp. 2116 - 2116, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1983QM89402107&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Gunning P; Ponte P; Blau H; Kedes L, 1983, 'α-Skeletal and α-cardiac actin genes are coexpressed in adult human skeletal muscle and heart', Molecular and Cellular Biology, 3, pp. 1985 - 1995, http://dx.doi.org/10.1128/mcb.3.11.1985

Engel J; Gunning P; Kedes L, 1982, 'Human cytoplasmic actin proteins are encoded by a multigene family', Molecular and Cellular Biology, 2, pp. 674 - 684, http://dx.doi.org/10.1128/MCB.2.6.674

Kedes DH; Gunning PW; Shooter EM, 1982, 'Nerve growth factor‐induced stimulation of α‐aminoisobutyric acid uptake in PC 12 cells: Evaluation of its biological significance', Journal of Neuroscience Research, 8, pp. 367 - 374, http://dx.doi.org/10.1002/jnr.490080225

Kedes DH; Gunning PW; Shooter EM, 1982, 'Nerve growth factor‐induced stimulation of α‐aminoisobutyric acid uptake in PC12 cells: Relationship to plasma membrane receptor occupancy', Journal of Neuroscience Research, 8, pp. 357 - 365, http://dx.doi.org/10.1002/jnr.490080224

Gunning PW; Béguin P; Shooter EM; Austin L; Jeffrey PL, 1981, 'Characterization of the association of two small molecular weight RNAs with eukaryotic polysomes.', Journal of Biological Chemistry, 256, pp. 6670 - 6675, http://dx.doi.org/10.1016/s0021-9258(19)69043-5

Gunning PW; Shooter EM; Austin L; Jeffrey PL, 1981, 'Differential and coordinate regulation of the eukaryotic small molecular weight RNAs.', Journal of Biological Chemistry, 256, pp. 6663 - 6669, http://dx.doi.org/10.1016/s0021-9258(19)69042-3

Gunning PW; Landreth GE; Bothwell MA; Shooter EM, 1981, 'Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells', Journal of Cell Biology, 89, pp. 240 - 245, http://dx.doi.org/10.1083/jcb.89.2.240

Engel JN; Gunning PW; Kedes L, 1981, 'Isolation and characterization of human actin genes', Proceedings of the National Academy of Sciences of the United States of America, 78, pp. 4674 - 4678, http://dx.doi.org/10.1073/pnas.78.8.4674

Gunning PW; Landreth GE; Layer P; Ignatius M; Shooter EM, 1981, 'Nerve growth factor-induced differentiation of PC12 cells: Evaluation of changes in RNA and DNA metabolism', Journal of Neuroscience, 1, pp. 368 - 379, http://dx.doi.org/10.1523/jneurosci.01-04-00368.1981

Gunning PW; Letourneau PC; Landreth GE; Shooter EM, 1981, 'The action of nerve growth factor and dibutyryl adenosine cyclic 3':5'-monophosphate on rat pheochromocytoma reveals distinct stages in the mechanisms underlying neurite outgrowth', Journal of Neuroscience, 1, pp. 1085 - 1095, http://dx.doi.org/10.1523/jneurosci.01-10-01085.1981

Gunning PW; Por SB; Langford CJ; Scheffer J; Austin L; Jeffrey PL, 1979, 'THE DIRECT MEASUREMENT OF THE AXOPLASMIC TRANSPORT OF INDIVIDUAL RNA SPECIES: TRANSFER BUT NOT RIBOSOMAL RNA IS TRANSPORTED', Journal of Neurochemistry, 32, pp. 1737 - 1743, http://dx.doi.org/10.1111/j.1471-4159.1979.tb02286.x

Gunning PW; Austin L; Jeffrey PL, 1979, 'THE TURNOVER AND SUBCELLULAR LOCALIZATION OF THE CHICK FOREBRAIN SMALL NUCLEAR RNAs', Journal of Neurochemistry, 32, pp. 1725 - 1736, http://dx.doi.org/10.1111/j.1471-4159.1979.tb02285.x

Por S; Gunning PW; Jeffrey PL; Austin L, 1978, 'Axonal transport of 4S RNA in the chick optic system', Neurochemical Research, 3, pp. 411 - 422, http://dx.doi.org/10.1007/BF00966323

Por SB; Komiya Y; McGregor A; Jeffrey PL; Gunning PW; Austin L, 1978, 'The axoplasmic transport of 4S RNA within the sciatic nerve of the chicken', Neuroscience Letters, 8, pp. 165 - 169, http://dx.doi.org/10.1016/0304-3940(78)90191-X

Gunning PW; Kaye PL; Austin L, 1977, 'IN VIVO RNA SYNTHESIS WITHIN THE RAT NODOSE GANGLIA', Journal of Neurochemistry, 28, pp. 1237 - 1240, http://dx.doi.org/10.1111/j.1471-4159.1977.tb12315.x

Gunning PW; Kaye PL; Austin L, 1977, 'IN VIVO SYNTHESIS OF RAPIDLY‐LABELLED RNA WITHIN THE RAT NODOSE GANGLIA FOLLOWING VAGOTOMY', Journal of Neurochemistry, 28, pp. 1245 - 1248, http://dx.doi.org/10.1111/j.1471-4159.1977.tb12317.x

Kaye PL; Gunning PW; Austin L, 1977, 'IN VIVO SYNTHESIS OF STABLE RNA WITHIN THE RAT NODOSE GANGLIA FOLLOWING VAGOTOMY', Journal of Neurochemistry, 28, pp. 1241 - 1243, http://dx.doi.org/10.1111/j.1471-4159.1977.tb12316.x

Langford CJ; Kaye PL; Austin L; Gunning PW, 1977, 'The in vivo synthesis of stable RNA within the vagus nerve following vagotomy', Neuroscience Letters, 6, pp. 15 - 19, http://dx.doi.org/10.1016/0304-3940(77)90058-1

GUNNING PW, 1976, 'SMALL MOLECULAR-WEIGHT RNAS - TOWARDS A BIOLOGICAL ROLE', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, 9, pp. 42 - 42, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1976DR08000104&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

KAYE PL; GUNNING PW, 1976, 'SYNTHESIS OF RNA IN NODOSE GANGLIA FOLLOWING AXON INJURY', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, 9, pp. 43 - 43, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1976DR08000107&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jeffrey PL; Austin L; Gunning PW, 1976, 'The RNA of chick forebrain synaptosomes', Neuroscience Letters, 2, pp. 153 - 158, http://dx.doi.org/10.1016/0304-3940(76)90007-0

GUNNING PW; JEFFREY PL; AUSTIN L, 1975, 'HIGH AND LOW-MOLECULAR WEIGHT RNA IN SUBFRACTIONS OF CHICK BRAIN', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, 8, pp. 86 - 86, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1975AM36400177&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bryce NS; Failes TW; Stehn JR; Baker K; Zahler S; Arzhaeva Y; Bischof L; Lyons C; Dedova I; Arndt GM; Gaus K; Goult BT; Hardeman EC; Gunning PW; Lock JG, 'The Limits of Phenotypic Plasticity in the Actin Cytoskeleton Revealed by Unbiased Chemical Perturbation', SSRN Electronic Journal, http://dx.doi.org/10.2139/ssrn.3299445

Conference Papers

Kumari R; Ven K; Chastney M; Peraenen J; Aaron J; Almeida-Souza L; Kremneva E; Poincloux R; Chew T; Gunning PW; Ivaska J; Lappalainen P, 2024, 'Functionally distinct actin filament nanoscale layers control focal adhesion assembly and microtubule-dependent disassembly', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY

Schrock D; Heydecker M; Weigert R; Hardeman E; Gunning P; Hammer JA, 2024, 'Tropomyosin and integrin engagement cooperate to promote actomyosin forces required for robust target cell killing.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY

Wang D; Gunning P; Wang Y; Di X; Wang F; Wanninayaka A; Jin D; Hardeman E, 2022, 'Cortical tension drug screen links mitotic spindle integrity to RhoA pathway', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, DC, Washington, pp. 159 - 159, presented at Annual Meeting of the American-Society-for-Cell-Biology/ European-Molecular-Biology-Organisation (ASCB/EMBO), DC, Washington, 03 December 2022 - 07 December 2022

Wang D; Gunning P; Wang Y; Di X; Wang F; Wanninayaka A; Jin D; Hardeman E, 2022, 'Cortical tension drug screen links mitotic spindle integrity to RhoA pathway', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, DC, Washington, pp. 54 - 54, presented at Annual Meeting of the American-Society-for-Cell-Biology/ European-Molecular-Biology-Organisation (ASCB/EMBO), DC, Washington, 03 December 2022 - 07 December 2022

Schrock DC; Heydecker M; Weigert R; Hardeman E; Gunning P; Hammer JA, 2022, 'Tropomyosin and engagement of the integrin LFA-1 cooperate to promote actomyosin-dependent force generation at the T cell immune synapse', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, DC, Washington, pp. 469 - 470, presented at Annual Meeting of the American-Society-for-Cell-Biology/ European-Molecular-Biology-Organisation (ASCB/EMBO), DC, Washington, 03 December 2022 - 07 December 2022

Heydecker M; Masedunskas A; Ebrahim S; Appaduray M; Shitara A; Bryce N; Gunning P; Hardeman E; Weigert R, 2022, 'Two Distinct F-Actin Force-Generating Modules Coordinate Membrane Remodeling During Membrane Trafficking in Live Mice', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, DC, Washington, pp. 308 - 309, presented at Annual Meeting of the American-Society-for-Cell-Biology/ European-Molecular-Biology-Organisation (ASCB/EMBO), DC, Washington, 03 December 2022 - 07 December 2022

Xu X; Wang Y; Bryce N; Tang K; Meagher NS; Kang EY; Kelemen LE; Köbel M; Ramus SJ; Friedlander M; Ford CE; Hardeman EC; Gunning PW, 2021, 'Abstract 1045: Combined targeting of actin/tropomyosin and microtubules underlies a potential treatment strategy of epithelial ovarian cancer with cell-cycle dependent synergy', in Cancer Research, American Association for Cancer Research (AACR), pp. 1045 - 1045, http://dx.doi.org/10.1158/1538-7445.am2021-1045

Xu X; Wang Y; Bryce N; Tang K; Meagher NS; Kang EY; Kelemen LE; Kobel M; Ramus SJ; Friedlander M; Ford CE; Hardeman EC; Gunning PW, 2021, 'Combined targeting of actin/tropomyosin and microtubules underlies a potential treatment strategy of epithelial ovarian cancer with cell-cycle dependent synergy.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 10 April 2021 - 21 May 2021

Gunning P; Wang Y; Stear JH; Swain A; Xu X; Bryce N; Alieva IB; Dugina VB; Cripe T; Stehn J; Hardeman EC, 2020, 'Anti-tropomyosin drugs prevent the rescue of vincristine-induced mitotic spindle defects', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-5817

Sao K; Jones TM; Doyle AD; Schevzov G; Gunning PW; Petrie RJ, 2018, 'Myosin II governs intracellular pressure and traction force by distinct tropomyosin-dependent mechanisms.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000505772703133&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sao K; Jones TM; Doyle AD; Schevzov G; Gunning PW; Petrie RJ, 2017, 'Myosin II governs intracellular pressure and traction force by distinct mechanisms.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, PA, Philadelphia, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), PA, Philadelphia, 02 December 2017 - 06 December 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664300605&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jeong S; Lim S; Schevzov G; Gunning PW; Helfman DM, 2016, 'Down-regulation of a high molecular weight tropomyosin Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, CA, San Francisco, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), CA, San Francisco, 03 December 2016 - 07 December 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396047200278&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Meiring J; Bryce NS; Hardeman EC; Gunning PW, 2016, 'Human cells contain enough tropomyosin to saturate all actin filaments', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, CA, San Francisco, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), CA, San Francisco, 03 December 2016 - 07 December 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396046900904&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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