By Professor Robert M Graham

Journal articles

Baker JG; Balaji P; Bond RA; Bylund DB; Eikenburg DC; Graham RM; Hieble JP; Hills R; Michel MC; Minneman KP; Parra S; Perez D; Summers R, 2023, 'Adrenoceptors in GtoPdb v.2023.1', IUPHAR/BPS Guide to Pharmacology CITE, 2023, http://dx.doi.org/10.2218/gtopdb/f4/2023.1

Ballinger ML; Pattnaik S; Mundra PA; Zaheed M; Rath E; Priestley P; Baber J; Ray-Coquard I; Isambert N; Causeret S; van der Graaf WTA; Puri A; Duffaud F; Le Cesne A; Seddon B; Chandrasekar C; Schiffman JD; Brohl AS; James PA; Kurtz JE; Penel N; Myklebost O; Meza-Zepeda LA; Pickett H; Kansara M; Waddell N; Kondrashova O; Pearson JV; Barbour AP; Li S; Nguyen TL; Fatkin D; Graham RM; Giannoulatou E; Green MJ; Kaplan W; Ravishankar S; Copty J; Powell JE; Cuppen E; van Eijk K; Veldink J; Ahn JH; Kim JE; Lor Randall R; Tucker K; Judson I; Sarin R; Ludwig T; Genin E; Deleuze JF; Haber M; Marshall G; Cairns MJ; Blay JY; Thomas DM, 2023, 'Heritable defects in telomere and mitotic function selectively predispose to sarcomas', Science, 379, pp. 253 - 260, http://dx.doi.org/10.1126/science.abj4784

Dang Q; Murphy B; Graham R; Puri A; Ford S; Marschner S; Chong J; Zaman S, 2023, 'Australian Patients’ Perspective of Quality of Hospital Care Following Spontaneous Coronary Artery Dissection', Heart, Lung and Circulation, 32, pp. S270 - S270, http://dx.doi.org/10.1016/j.hlc.2023.06.347

McGrath-Cadell L; Hesselson S; Thompson J; Iismaa S; Tarr I; Muller D; Kovacic J; Graham R; Giannoulatou E, 2023, 'COL3A1 Mutations in Spontaneous Coronary Artery Dissection', Heart Lung and Circulation, 32, pp. s126, http://dx.doi.org/10.1016/j.hlc.2023.06.757

Bax M; Junday K; Tarr I; Hesselson S; McGrath-Cadell L; Iismaa S; Giannoulatou E; Graham R, 2023, 'Proteomic Analysis Reveals TGFB Pathway Perturbation in Spontaneous Coronary Artery Dissection (SCAD) Patient iPSC Derived Endothelial Cells', Heart, Lung and Circulation, 32, pp. S416 - S416, http://dx.doi.org/10.1016/j.hlc.2023.06.585

Bax M; Romanov V; Junday K; Giannoulatou E; Martinac B; Kovacic JC; Liu R; Iismaa SE; Graham RM, 2022, 'Arterial dissections: Common features and new perspectives', Frontiers in Cardiovascular Medicine, 9, http://dx.doi.org/10.3389/fcvm.2022.1055862

Kashyap V; Gharleghi R; Li DD; McGrath-Cadell L; Graham RM; Ellis C; Webster M; Beier S, 2022, 'Accuracy of vascular tortuosity measures using computational modelling', Scientific Reports, 12, pp. 865, http://dx.doi.org/10.1038/s41598-022-04796-w

Bogush N; Tan L; Naqvi E; Calvert JW; Graham RM; Taylor WR; Naqvi N; Husain A, 2022, 'Remuscularization with triiodothyronine and β1-blocker therapy reverses post-ischemic left ventricular dysfunction and adverse remodeling', Scientific Reports, 12, http://dx.doi.org/10.1038/s41598-022-12723-2

Kim SK; Wing-Lun E; Chandrasekhar J; Puri A; Burgess S; Ford TJ; Kovacic J; Graham RM; Psaltis PJ; Zaman S, 2022, 'The Australian New Zealand Spontaneous Coronary Artery Dissection (ANZ-SCAD) Registry – A Multi-Centre Cohort Study: Protocol, Background and Significance', Heart Lung and Circulation, 31, pp. 1612 - 1618, http://dx.doi.org/10.1016/j.hlc.2022.08.018

Graham RM, 2022, 'Adverse events after spontaneous coronary artery dissection', Heart, 108, pp. 1506 - 1507, http://dx.doi.org/10.1136/heartjnl-2022-321136

Murphy BM; Rogerson MC; Hesselson S; Iismaa SE; Graham RM; Jackson AC, 2022, 'Psychosocial impacts of spontaneous coronary artery dissection: A qualitative study', Plos One, 17, http://dx.doi.org/10.1371/journal.pone.0273978

Nicks AM; Holman SR; Chan AY; Tsang M; Young PE; Humphreys DT; Naqvi N; Husain A; Li M; Smith NJ; Iismaa SE; Graham RM, 2022, 'Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts', Journal of Molecular and Cellular Cardiology, 170, pp. 47 - 59, http://dx.doi.org/10.1016/j.yjmcc.2022.05.012

Tarr I; Hesselson S; Iismaa SE; Rath E; Monger S; Troup M; Mishra K; Wong CMY; Hsu PC; Junday K; Humphreys DT; Adlam D; Webb TR; Baranowska-Clarke AA; Hamby SE; Carss KJ; Samani NJ; Bax M; McGrath-Cadell L; Kovacic JC; Dunwoodie SL; Fatkin D; Muller DWM; Graham RM; Giannoulatou E, 2022, 'Exploring the Genetic Architecture of Spontaneous Coronary Artery Dissection Using Whole-Genome Sequencing', Circulation Genomic and Precision Medicine, 15, pp. 267 - 277, http://dx.doi.org/10.1161/CIRCGEN.121.003527

Anthony C; Imran M; Pouliopoulos J; Emmanuel S; Iliff J; Liu Z; Moffat K; Ru Qiu M; McLean CA; Stehning C; Puntmann V; Vassiliou V; Ismail TF; Gulati A; Prasad S; Graham RM; McCrohon J; Holloway C; Kotlyar E; Muthiah K; Keogh AM; Hayward CS; MacDonald PS; Jabbour A, 2022, 'Cardiovascular Magnetic Resonance for Rejection Surveillance After Cardiac Transplantation', Circulation, 145, pp. 1811 - 1824, http://dx.doi.org/10.1161/CIRCULATIONAHA.121.057006

Wu J; Nicks AM; Skowno JJ; Feneley MP; Graham RM; Iismaa SE, 2022, 'Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery', Journal of Visualized Experiments, http://dx.doi.org/10.3791/64004-v

Wu J; Nicks AM; Skowno JJ; Feneley MP; Graham RM; Iismaa SE, 2022, 'Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery', Journal of Visualized Experiments, 2022, http://dx.doi.org/10.3791/64004

Mouat MA; Wilkins BP; Ding E; Govindaraju H; Coleman JLJ; Graham RM; Turner N; Smith NJ, 2022, 'Metabolic Profiling of Mice with Deletion of the Orphan G Protein-Coupled Receptor, GPR37L1', Cells, 11, http://dx.doi.org/10.3390/cells11111814

Yu ZY; Gong H; Kesteven S; Guo Y; Wu J; Li JV; Cheng D; Zhou Z; Iismaa SE; Kaidonis X; Graham RM; Cox CD; Feneley MP; Martinac B, 2022, 'Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice', Nature Cardiovascular Research, 1, pp. 577 - 591, http://dx.doi.org/10.1038/s44161-022-00082-0

Bax M; Junday K; Iismaa S; Hesselson S; Tarr I; McGrath-Cadell L; Dunwoodie S; Giannoulatou E; Graham R, 2022, 'Induced Pluripotent Stem Cell-Derived Models of Spontaneous Coronary Artery Dissection', Heart, Lung and Circulation, 31, pp. S87 - S87, http://dx.doi.org/10.1016/j.hlc.2022.06.097

Vatner SF; Zhang J; Vyzas C; Mishra K; Graham RM; Vatner DE, 2021, 'Vascular Stiffness in Aging and Disease', Frontiers in Physiology, 12, http://dx.doi.org/10.3389/fphys.2021.762437

Nicks AM; Holman SR; Chan AY; Pang C-HJ; Tsang M; Naqvi N; Husain A; Li M; Humphreys DT; Smith NJ; Iismaa SE; Graham RM, 2021, 'Abstract 11948: A Standardized Method to Isolate and Purify Cardiomyocytes from Individual Mouse Hearts Irrespective of Postnatal Age', Circulation, 144, pp. a11948 - a11948, http://dx.doi.org/10.1161/circ.144.suppl_1.11948

McGrath-Cadell L; Hesselson S; Tarr I; Iismaa SE; Bax M; Junday K; Dunwoodie SE; Fatkin D; Kovacic J; Muller DWM; Giannoulatou E; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection (SCAD) and a family history of aortic artery dissection, a case series', European Heart Journal, 42, pp. ehab724.2787, http://dx.doi.org/10.1093/eurheartj/ehab724.2787

Naqvi N; Iismaa SE; Graham RM; Husain A, 2021, 'Mechanism-Based Cardiac Regeneration Strategies in Mammals', Frontiers in Cell and Developmental Biology, 9, http://dx.doi.org/10.3389/fcell.2021.747842

Mouat MA; Coleman JLJ; Wu J; dos Remedios CG; Feneley MP; Graham RM; Smith NJ, 2021, 'Involvement of GPR37L1 in murine blood pressure regulation and human cardiac disease pathophysiology', American Journal of Physiology Heart and Circulatory Physiology, 321, pp. H807 - H817, http://dx.doi.org/10.1152/ajpheart.00198.2021

Altosaar K; Balaji P; Bond RA; Bylund DB; Cotecchia S; Devost D; Doze VA; Eikenburg DC; Gora S; Goupil E; Graham RM; Hébert T; Hieble JP; Hills R; Kan S; Machkalyan G; Michel MC; Minneman KP; Parra S; Perez D; Sleno R; Summers R; Zylbergold P, 2021, 'Adrenoceptors in GtoPdb v.2021.3', IUPHAR/BPS Guide to Pharmacology CITE, 2021, http://dx.doi.org/10.2218/gtopdb/f4/2021.3

Kaidonis X; Niu W; Chan AY; Kesteven S; Wu J; Iismaa SE; Vatner S; Feneley M; Graham RM, 2021, 'Adaptation to exercise-induced stress is not dependent on cardiomyocyte α1A-adrenergic receptors', Journal of Molecular and Cellular Cardiology, 155, pp. 78 - 87, http://dx.doi.org/10.1016/j.yjmcc.2021.02.010

Guo Y; Yu ZY; Wu J; Gong H; Kesteven S; Iismaa SE; Chan AY; Holman S; Pinto S; Pironet A; Cox CD; Graham RM; Vennekens R; Feneley MP; Martinac B, 2021, 'The ca2+-activated cation channel trpm4 is a positive regulator of pressure overload-induced cardiac hypertrophy', Elife, 10, http://dx.doi.org/10.7554/eLife.66582

Anthony C; Imran M; Pouliopoulos J; Emmanuel S; Iliff JW; Moffat KJ; Ross J; Graham RM; Kotlyar E; Muthiah K; Keogh AM; Hayward CS; Macdonald P; Jabbour A, 2021, 'Everolimus for the Prevention of Calcineurin-Inhibitor-Induced Left Ventricular Hypertrophy After Heart Transplantation (RADTAC Study)', Jacc Heart Failure, 9, pp. 301 - 313, http://dx.doi.org/10.1016/j.jchf.2021.01.007

Ngo T; Ilatovskiy AV; Stewart AG; Coleman JLJ; McRobb FM; Riek RP; Graham RM; Abagyan R; Kufareva I; Smith NJ, 2021, 'Retraction Note: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors (Nature Chemical Biology, (2017), 13, 2, (235-242), 10.1038/nchembio.2266)', Nature Chemical Biology, 17, pp. 501, http://dx.doi.org/10.1038/s41589-021-00746-1

Tan L; Bogush N; Naqvi E; Calvert JW; Graham RM; Taylor WR; Naqvi N; Husain A, 2021, 'Thyroid hormone plus dual-specificity phosphatase-5 siRNA increases the number of cardiac muscle cells and improves left ventricular contractile function in chronic doxorubicin-injured hearts', Theranostics, 11, pp. 4790 - 4808, http://dx.doi.org/10.7150/thno.57456

Yu ZY; Gong H; Wu J; Dai Y; Kesteven SH; Fatkin D; Martinac B; Graham RM; Feneley MP, 2021, 'Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload', Frontiers in Cell and Developmental Biology, 9, http://dx.doi.org/10.3389/fcell.2021.639509

Mouat MA; Jackson KL; Coleman JLJ; Paterson MR; Graham RM; Head GA; Smith NJ, 2021, 'Deletion of Orphan G Protein-Coupled Receptor GPR37L1 in Mice Alters Cardiovascular Homeostasis in a Sex-Specific Manner', Frontiers in Pharmacology, 11, http://dx.doi.org/10.3389/fphar.2020.600266

Iismaa SE; Hesselson S; McGrath-Cadell L; Muller DW; Fatkin D; Giannoulatou E; Kovacic J; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women', Heart Lung and Circulation, 30, pp. 27 - 35, http://dx.doi.org/10.1016/j.hlc.2020.05.110

Bax M; Junday K; Hesselson S; Iismaa S; Tarr I; McGrath-Cadell L; Dunwoodie S; Fatkin D; Kovacic J; Muller D; Giannoulatou E; Graham R, 2021, 'Modelling Spontaneous Coronary Artery Dissection With iPSC-Derived Vascular Cells', Heart Lung and Circulation, 30, pp. s131, http://dx.doi.org/10.1016/j.hlc.2021.06.089

McGrath-Cadell L; Iismaa SE; Hesselson S; Muller DW; Fatkin D; Giannoulatou E; Kovacic JC; Graham RM, 2021, 'Recent Updates on Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia', International Journal of Integrative Cardiology, 3, http://dx.doi.org/10.47275/2690-862x-121

Bogush N; Tan L; Naib H; Faizullabhoy E; Calvert JW; Iismaa SE; Gupta A; Ramchandran R; Martin DIK; Graham RM; Husain A; Naqvi N, 2020, 'DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling', Scientific Reports, 10, pp. 21918, http://dx.doi.org/10.1038/s41598-020-78825-x

Nicks AM; Kesteven SH; Li M; Wu J; Chan AY; Naqvi N; Husain A; Feneley MP; Smith NJ; Iismaa SE; Graham RM, 2020, 'Pressure overload by suprarenal aortic constriction in mice leads to left ventricular hypertrophy without c-Kit expression in cardiomyocytes', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-72273-3

Carss KJ; Baranowska AA; Armisen J; Webb TR; Hamby SE; Premawardhana D; Al-Hussaini A; Wood A; Wang Q; Deevi SVV; Vitsios D; Lewis SH; Kotecha D; Bouatia-Naji N; Hesselson S; Iismaa SE; Tarr I; McGrath-Cadell L; Muller DW; Dunwoodie SL; Fatkin D; Graham RM; Giannoulatou E; Samani NJ; Petrovski S; Haefliger C; Adlam D, 2020, 'Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing', Circulation Genomic and Precision Medicine, 13, pp. E003030, http://dx.doi.org/10.1161/CIRCGEN.120.003030

Coleman JLJ; Ngo T; Smythe RE; Cleave AJ; Jones NM; Graham RM; Smith NJ, 2020, 'The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-76384-9

Suzuki AS; Yagi R; Kimura MY; Iwamura C; Shinoda K; Onodera A; Hirahara K; Tumes DJ; Koyama-Nasu R; Iismaa SE; Graham RM; Motohashi S; Nakayama T, 2020, 'Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation', Frontiers in Immunology, 11, http://dx.doi.org/10.3389/fimmu.2020.01536

Thavapalachandran S; Grieve SM; Hume RD; Le TYL; Raguram K; Hudson JE; Pouliopoulos J; Figtree GA; Dye RP; Barry AM; Brown P; Lu J; Coffey S; Kesteven SH; Mills RJ; Rashid FN; Taran E; Kovoor P; Thomas L; Denniss AR; Kizana E; Asli NS; Xaymardan M; Feneley MP; Graham RM; Harvey RP; Chong JJH, 2020, 'Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction', Science Translational Medicine, 12, http://dx.doi.org/10.1126/scitranslmed.aay2140

Situ Y; Baric J; Han W; Law M; Fatkin D; Graham R, 2020, '055 Prevalence and Patient Awareness of Cardiovascular Risk Factors in a Community-Based Australian Cohort', Heart, Lung and Circulation, 29, pp. S62 - S62, http://dx.doi.org/10.1016/j.hlc.2020.09.062

Coleman JLJ; Ngo T; Schmidt J; Mrad N; Liew CK; Jones NM; Graham RM; Smith NJ, 2019, 'Retraction: Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity (Science Signaling (2016) 9 (ra36) DOI: 10.1126/scisignal.aad1089)', Science Signaling, 12, http://dx.doi.org/10.1126/scisignal.aba2063

Mishra K; Junday K; Wong CMY; Chan AY; Hesselson S; Muller DW; Iismaa SE; Mehta A; Graham RM, 2019, 'Generation of VCCRIi001-A, a human induced pluripotent stem cell line, from a patient with spontaneous coronary artery dissection', Stem Cell Research, 41, http://dx.doi.org/10.1016/j.scr.2019.101584

Tan L; Bogush N; Naib H; Perry J; Calvert JW; Martin DIK; Graham RM; Naqvi N; Husain A, 2019, 'Redox activation of JNK2α2 mediates thyroid hormone-stimulated proliferation of neonatal murine cardiomyocytes', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-53705-1

McGrath-Cadell L; Hesselson S; Iismaa SE; Mishra K; Wong CMY; Fatkin D; Dunwoodie SL; Harvey R; Holloway CJ; Muller DWM; Giannoulatou E; Graham RM, 2019, 'P5540Familial clustering of spontaneous coronary artery dissection', European Heart Journal, 40, pp. ehz746.0486, http://dx.doi.org/10.1093/eurheartj/ehz746.0486

Altosaar K; Balaji P; Bond RA; Bylund DB; Cotecchia S; Devost D; Doze VA; Eikenburg DC; Gora S; Goupil E; Graham RM; Hébert T; Hieble JP; Hills R; Kan S; Machkalyan G; Michel MC; Minneman KP; Parra S; Perez D; Sleno R; Summers R; Zylbergold P, 2019, 'Adrenoceptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database', IUPHAR/BPS Guide to Pharmacology CITE, 2019, http://dx.doi.org/10.2218/gtopdb/f4/2019.4

Kaidonis X; Niu W; Chan AY; Kesteven S; Wu J; Iismaa SE; Feneley M; Graham RM, 2019, 'Abstract 579: Involvement of the Alpha 1A-Adrenergic Receptor in the Cardiac Adaptation to Physiological Stress', Circulation Research, 125, http://dx.doi.org/10.1161/res.125.suppl_1.579

Alankarage D; Ip E; Szot JO; Munro J; Blue GM; Harrison K; Cuny H; Enriquez A; Troup M; Humphreys DT; Wilson M; Harvey RP; Sholler GF; Graham RM; Ho JWK; Kirk EP; Pachter N; Chapman G; Winlaw DS; Giannoulatou E; Dunwoodie SL, 2019, 'Identification of clinically actionable variants from genome sequencing of families with congenital heart disease', Genetics in Medicine, 21, pp. 1111 - 1120, http://dx.doi.org/10.1038/s41436-018-0296-x

Chew HC; Iyer A; Connellan M; Scheuer S; Villanueva J; Gao L; Hicks M; Harkness M; Soto C; Dinale A; Nair P; Watson A; Granger E; Jansz P; Muthiah K; Jabbour A; Kotlyar E; Keogh A; Hayward C; Graham R; Spratt P; Macdonald P; Dhital K, 2019, 'Outcomes of Donation After Circulatory Death Heart Transplantation in Australia', Journal of the American College of Cardiology, 73, pp. 1447 - 1459, http://dx.doi.org/10.1016/j.jacc.2018.12.067

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