By Professor Tri Giang Phan

Journal articles

Vazquez-Lombardi R; Loetsch C; Zinkl D; Jackson J; Schofield P; Deenick EK; King C; Phan TG; Webster KE; Sprent J; Christ D; Vazquez Lombardi R, 2017, 'Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells', Nature Communications, 8, pp. 15373, http://dx.doi.org/10.1038/ncomms15373

Vennin C; Chin VT; Warren SC; Lucas MC; Herrmann D; Magenau A; Melenec P; Walters SN; Del Monte-Nieto G; Conway JRW; Nobis M; Allam AH; McCloy RA; Currey N; Pinese M; Boulghourjian A; Zaratzian A; Adam AAS; Heu C; Nagrial AM; Chou A; Steinmann A; Drury A; Froio D; Giry-Laterriere M; Harris NLE; Phan T; Jain R; Weninger W; McGhee EJ; Whan R; Johns AL; Samra JS; Chantrill L; Gill AJ; Kohonen-Corish M; Harvey RP; Biankin AV; Evans TRJ; Anderson KI; Grey ST; Ormandy CJ; Gallego-Ortega D; Wang Y; Samuel MS; Sansom OJ; Burgess A; Cox TR; Morton JP; Pajic M; Timpson P, 2017, 'Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis', Science Translational Medicine, 9, http://dx.doi.org/10.1126/scitranslmed.aai8504

Phan TG; Tangye SG, 2017, 'Memory B cells: total recall', Current Opinion in Immunology, 45, pp. 132 - 140, http://dx.doi.org/10.1016/j.coi.2017.03.005

Tangye SG; Pillay B; Randall KL; Avery DT; Tri GP; Gray P; Ziegler JB; Smart JM; Peake J; Arkwright PD; Hambleton S; Orange J; Goodnow CC; Uzel G; Casanova J-L; Lugo Reyes SO; Freeman AF; Su HC; Ma CS, 2017, 'Dedicator of cytokinesis 8-deficient CD4(+) T cells are biased to a T(H)2 effector fate at the expense of T(H)1 and T(H)17 cells', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 139, pp. 933 - 949, http://dx.doi.org/10.1016/j.jaci.2016.07.016

Tangye SG; Pillay B; Randall KL; Avery DT; Phan TG; Gray P; Ziegler JB; Smart JM; Peake J; Arkwright PD; Hambleton S; Orange J; Goodnow CC; Uzel G; Casanova JL; Lugo Reyes SO; Freeman AF; Su HC; Ma CS, 2017, 'Dedicator of cytokinesis 8–deficient CD4⁺ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells', Journal of Allergy and Clinical Immunology, 139, pp. 933 - 949, http://dx.doi.org/10.1016/j.jaci.2016.07.016

Moran I; Phan TG, 2017, 'Fate mapping and transcript profiling of germinal center cells by two-photon photoconversion', , 1623, pp. 59 - 72, http://dx.doi.org/10.1007/978-1-4939-7095-7_5

Ma CS; Wong N; Rao G; Nguyen A; Avery DT; Payne K; Torpy J; O'Young P; Deenick E; Bustamante J; Puel A; Okada S; Kobayashi M; Martinez-Barricarte R; Elliott M; Kilic SS; Baghdadi JE; Minegishi Y; Bousfiha A; Robertson N; Hambleton S; Arkwright PD; French M; Blincoe AK; Hsu P; Campbell DE; Stormon MO; Wong M; Adelstein S; Fulcher DA; Cook MC; Stepensky P; Boztug K; Beier R; Ikincioğullari A; Ziegler JB; Gray P; Picard C; Boisson-Dupuis S; Phan TG; Grimbacher B; Warnatz K; Holland SM; Uzel G; Casanova JL; Tangye SG, 2016, 'Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4⁺ T cells into distinct effector subsets', Journal of Experimental Medicine, 213, pp. 1589 - 1608, http://dx.doi.org/10.1084/jem.20151467

Amiezer M; Phan TG, 2016, 'Disentangling Tfr cells from Treg cells and Tfh cells: How to untie the Gordian knot', European Journal of Immunology, 46, pp. 1101 - 1104, http://dx.doi.org/10.1002/eji.201646389

Chang J; Ip M; Yang M; Wong B; Power T; Lin L; Xuan W; Phan TG; Leong RW, 2016, 'The learning curve, interobserver, and intraobserver agreement of endoscopic confocal laser endomicroscopy in the assessment of mucosal barrier defects', Gastrointestinal Endoscopy, http://dx.doi.org/10.1016/j.gie.2015.08.045

Nakagawa R; Leyland R; Meyer-Hermann M; Lu D; Turner M; Arbore G; Phan TG; Brink R; Vigorito E, 2016, 'MicroRNA-155 controls affinity-based selection by protecting c-MYC+B cells from apoptosis', Journal of Clinical Investigation, 126, pp. 377 - 388

Lawson MA; McDonald MM; Kovacic N; Khoo WH; Terry RL; Down J; Kaplan W; Paton-Hough J; Fellows C; Pettitt JA; Dear TN; Van Valckenborgh E; Baldock PA; Rogers MJ; Eaton CL; Vanderkerken K; Pettit AR; Quinn JMW; Zannettino ACW; Phan TG; Croucher PI, 2015, 'Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche', Nature Communications, 6, http://dx.doi.org/10.1038/ncomms9983

Vazquez-Lombardi R; Phan TG; Zimmermann C; Lowe D; Jermutus L; Christ D, 2015, 'Challenges and opportunities for non-antibody scaffold drugs', Drug Discovery Today, 20, pp. 1271 - 1283, http://dx.doi.org/10.1016/j.drudis.2015.09.004

Ma CS; Wong N; Rao G; Avery DT; Torpy J; Hambridge T; Bustamante J; Okada S; Stoddard JL; Deenick EK; Pelham SJ; Payne K; Boisson-Dupuis S; Puel A; Kobayashi M; Arkwright PD; Kilic SS; El Baghdadi J; Nonoyama S; Minegishi Y; Mahdaviani SA; Mansouri D; Bousfiha A; Blincoe AK; French MA; Hsu P; Campbell DE; Stormon MO; Wong M; Adelstein S; Smart JM; Fulcher DA; Cook MC; Phan TG; Stepensky P; Boztug K; Kansu A; Ikincioʇullari A; Baumann U; Beier R; Roscioli T; Ziegler JB; Gray P; Picard C; Grimbacher B; Warnatz K; Holland SM; Casanova JL; Uzel G; Tangye SG, 2015, 'Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies', Journal of Allergy and Clinical Immunology, 136, pp. 993 - 1006.e1, http://dx.doi.org/10.1016/j.jaci.2015.05.036

Tangye SG; Brink R; Goodnow CC; Phan TG, 2015, 'SnapShot: Interactions between B Cells and T Cells', Cell, 162, pp. 926 - 926.e1, http://dx.doi.org/10.1016/j.cell.2015.07.055

Phan TG; Long GV; Scolyer RA, 2015, 'Multiple checkpoints on the long road towards cancer immunotherapy', Immunology and Cell Biology, 93, pp. 323 - 325, http://dx.doi.org/10.1038/icb.2015.12

Suan D; Nguyen A; Moran I; Bourne K; Hermes JR; Arshi M; Hampton HR; Tomura M; Miwa Y; Kelleher AD; Kaplan W; Deenick EK; Tangye SG; Brink R; Chtanova T; Phan TG, 2015, 'T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses', Immunity, 42, pp. 704 - 718, http://dx.doi.org/10.1016/j.immuni.2015.03.002

Antignano F; Zaph C, 2015, 'Regulation of CD4 T-cell differentiation and inflammation by repressive histone methylation', IMMUNOLOGY AND CELL BIOLOGY, 93, pp. 245 - 252, http://dx.doi.org/10.1038/icb.2014.115

Phan TG; Long GV; Scolyer RA, 2015, 'Multiple checkpoints on the long road towards cancer immunotherapy', Immunology and Cell Biology, http://dx.doi.org/10.1038/icb.2015.12

Butt D; Chan TD; Bourne K; Hermes JR; Nguyen A; Statham A; O'Reilly LA; Strasser A; Price S; Schofield P; Christ D; Basten A; Ma CS; Tangye SG; Phan TG; Rao VK; Brink R, 2015, 'FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production', Immunity, 42, pp. 890 - 902, http://dx.doi.org/10.1016/j.immuni.2015.04.010

Junankar S; Shay G; Jurczyluk J; Ali N; Down J; Pocock N; Parker A; Nguyen A; Sun S; Kashemirov B; McKenna CE; Croucher PI; Swarbrick A; Weilbaecher K; Phan TG; Rogers MJ, 2015, 'Real-Time Intravital Imaging Establishes Tumor-Associated Macrophages as the Extraskeletal Target of Bisphosphonate Action in Cancer', Cancer Discovery, 5, pp. 35 - 42, http://dx.doi.org/10.1158/2159-8290.CD-14-0621

Brink R; Paus D; Bourne K; Hermes JR; Gardam S; Phan TG; Chan TD, 2015, 'The SWHEL system for high-resolution analysis of in vivo antigen-specific T-dependent B cell responses', Methods in Molecular Biology, 1291, pp. 103 - 123, http://dx.doi.org/10.1007/978-1-4939-2498-1_9

Chang J; Ip MH; Yang M; Wong B; Arshi M; Phan T; Leong RW, 2015, '306 Impaired Mucosal Permeability Underlies Ongoing Irritable Bowel Syndrome-Like Symptoms, in Patients With Inflammatory Bowel Disease Who Have Achieved Mucosal Healing', Gastroenterology, 148, pp. S - 67, http://dx.doi.org/10.1016/s0016-5085(15)30235-3

Sasson S; Smith S; Sewell WA; Morey A; Danta M; Emmett L; Kelleher AD; Fay K; Phan T, 2014, 'MONOCLONAL B-CELL POPULATION OF INDETERMINANT MALIGNANT POTENTIAL IN THE SETTING OF ATYPICAL CVID ASSOCIATED WITH LYMPHADENOPATHY AND SPLENOMEGALY', INTERNAL MEDICINE JOURNAL, 44, pp. 33 - 33, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342722800109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lee WM; Upadhya A; Reece PJ; Phan TG, 2014, 'Fabricating low cost and high performance elastomer lenses using hanging droplets', Biomedical Optics Express, 5, pp. 1626 - 1635, http://dx.doi.org/10.1364/BOE.5.001626

Lee WM; Upadhya A; Phan T, 2014, 'Mobile microscopy on the move', Proceedings of SPIE - The International Society for Optical Engineering, 9023, http://dx.doi.org/10.1117/12.2032754

Chtanova T; Hampton HR; Waterhouse LA; Wood K; Tomura M; Miwa Y; Mackay CR; Brink R; Phan TG, 2014, 'Real-time interactive two-photon photoconversion of recirculating lymphocytes for discontinuous cell tracking in live adult mice', Journal of Biophotonics, 7, pp. 425 - 433, http://dx.doi.org/10.1002/jbio.201200175

Suan D; Hampton HR; Tomura M; Kanagawa O; Chtanova T; Phan TG, 2013, 'Optimizing Fluorescence Excitation and Detection for Intravital Two-Photon Microscopy', , 113, pp. 311 - 323, http://dx.doi.org/10.1016/B978-0-12-407239-8.00014-8

Gray EE; Friend S; Suzuki K; Phan TG; Cyster JG, 2012, 'Subcapsular sinus macrophage fragmentation and CD169(+) Bleb acquisition by closely associated IL-17-committed innate-like lymphocytes', PLoS ONE, 7, pp. e38258, http://dx.doi.org/10.1371/journal.pone.0038258

Tri P; Hampton H; Tomura M; Kanagawa O; Mackay C; Brink R; Chtanova T, 2011, 'Optical marking of migrating lymphocytes by two-photon photoconversion for single cell tracking and fate mapping', JOURNAL OF IMMUNOLOGY, 186, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209751703169&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Toong C; Adelstein S; Phan TG, 2011, 'Clearing the complexity: immune complexes and their treatment in lupus nephritis', International Journal of Nephrology and Renovascular Disease, 4, pp. 17 - 28, http://dx.doi.org/10.2147/IJNRD.S10233

Phan TG; Chtanova T, 2010, 'Border patrol: SCS macrophages activate iNKT cells too', Immunology and Cell Biology, 88, pp. 619 - 621, http://dx.doi.org/10.1038/icb.2010.71

Phan TG; Brink R, 2010, 'Micromanaging memory with immunoglobulin microclusters', Immunity, 32, pp. 732 - 733, http://dx.doi.org/10.1016/j.immuni.2010.06.009

Phan TG; Bullen A, 2010, 'Practical intravital two-photon microscopy for immunological research: faster, brighter, deeper', Immunology and Cell Biology, 88, pp. 438 - 444, http://dx.doi.org/10.1038/icb.2009.116

Grigorova IL; Schwab SR; Phan TG; Pham THM; Okada T; Cyster JG, 2009, 'Erratum: Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells (Nature Immunology (2009) vol. 10 (58-65))', Nature Immunology, 10, pp. 223, http://dx.doi.org/10.1038/ni0209-223e

Grigorova IL; Schwab SR; Phan TG; Pham THM; Okada T; Cyster JG, 2009, 'Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells', Nature Immunology, 10, pp. 58 - 65, http://dx.doi.org/10.1038/ni.1682

Phan TG; Green JA; Gray EE; Xu Y; Cyster JG, 2009, 'Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation', Nature Immunology, 10, pp. 786 - 793, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19503106

Phan TG; Grey EE; Cyster JG, 2009, 'The microanatomy of B cell activation', Current Opinion in Immunology, 21, pp. 258 - 265, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19481917

Brink R; Phan TA; Paus D; Chan TV, 2008, 'Visualizing the effects of antigen affinity on T-dependent B-cell differentiation', Immunology and Cell Biology, 86, pp. 31 - 39, http://dx.doi.org/10.1038/sj.icb.7100143

Phan TG; Grigorova I; Okada T; Cyster JG, 2007, 'Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells', Nature Immunology, 8, pp. 992 - 1000, http://dx.doi.org/10.1038/ni1494

Phan TG; Paus D; Chan TD; Turner ML; Nutt SL; Basten A; Brink R, 2006, 'High affinity germinal center B cells are actively selected into the plasma cell compartment', Journal of Experimental Medicine, 203, pp. 2419 - 2424, http://dx.doi.org/10.1084/jem.20061254

Paus D; Tri GP; Chan TD; Gardam S; Basten A; Brink R, 2006, 'Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation', Journal of Experimental Medicine, 203, pp. 1081 - 1091, http://dx.doi.org/10.1084/jem.20060087

Ho PW; Reutens DC; Phan TG; Wright PM; Markus R; Indra I; Young D; Donnan GA, 2005, 'Is white matter involved in patients entered into typical trials of neuroprotection?', Stroke, 36, pp. 2742 - 2744, http://dx.doi.org/10.1161/01.STR.0000189748.52500.a7

Koga M; Reutens DC; Wright P; Phan T; Markus R; Pedreira B; Fitt G; Lim I; Donnan GA, 2005, 'The existence and evolution of diffusion-perfusion mismatched tissue in white and gray matter after acute stroke', Stroke, 36, pp. 2132 - 2137, http://dx.doi.org/10.1161/01.STR.0000181066.23213.8f

Tri GP; Gardam S; Basten A; Brink R, 2005, 'Altered migration, recruitment, and somatic hypermutation in the early response of marginal zone B cells to T cell-dependent antigen', Journal of Immunology, 174, pp. 4567 - 4578, http://dx.doi.org/10.4049/jimmunol.174.8.4567

Ellyard JI; Avery DT; Phan TG; Hare NJ; Hodgkin PD; Tangye SG, 2004, 'Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow', Blood, 103, pp. 3805 - 3812, http://dx.doi.org/10.1182/blood-2003-09-3109

Phan TG; Amesbury M; Gardam S; Crosbie J; Hasbold J; Hodgkin PD; Basten A; Brink R, 2003, 'B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells', Journal of Experimental Medicine, 197, pp. 845 - 860, http://dx.doi.org/10.1084/jem.20022144

Phan TG; Strasser SI; Koorey D; McCaughan GW; Rimmer J; Dunckley H; Goddard L; Adelstein S, 2003, 'Passive transfer of nut allergy after liver transplantation', Archives of Internal Medicine, 163, pp. 237 - 239, http://dx.doi.org/10.1001/archinte.163.2.237

Phan TG; Gordon TP; Tattersall MHN; Loblay RH, 2002, 'Octreotide therapy for the Sjögren syndrome [5]', Annals of Internal Medicine, 137, pp. 777 - 778, http://dx.doi.org/10.7326/0003-4819-137-9-200211050-00031

Phan TG; Wright PM; Markus R; Howells DW; Davis SM; Donnan GA, 2002, 'Salvaging the ischaemic penumbra: More than just reperfusion?', Clinical and Experimental Pharmacology and Physiology, 29, pp. 1 - 10, http://dx.doi.org/10.1046/j.1440-1681.2002.03609.x

Tri GP; Wong RCW; Adelstein S, 2002, 'Autoantibodies to extractable nuclear antigens: Making detection and interpretation more meaningful', Clinical and Diagnostic Laboratory Immunology, 9, pp. 1 - 7, http://dx.doi.org/10.1128/CDLI.9.1.1-7.2002

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