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Peripheral nerve injury often results in persistent and debilitating neuropathic pain. My overall objective is to understand the immunological mechanisms responsible for such pain.
Electroconvulsive therapy (ECT) is a highly effective treatment for depression, used in Australia and throughout the world to treat severe depression that has not responded to other treatments.
Unlimited access to palatable high fat foods, in conjunction with a sedentary life style, has led to increased obesity. Exactly what mechanisms drive over consumption of energy rich foods and override mechanisms that normally regulate body weight?
This project will provide important information regarding the pharmacological mechanisms by which NPY acts to suppress seizures in animal models of epilepsy. It will provide strategies regarding potential new treatments of absence epilepsy.
Utilising our geographically abundant solar energy and through designing novel photoelectrochemical and photocatalytic systems, the research provides an ultimately clean solution by efficiently harnessing and converting the solar energy to hydrogen while remediating wastewater.
This project will produce an easy-to-use prototype system for guiding blind and visually impaired (BVI) people both indoors and outdoors and delivering location based information.
To achieve high economical efficiency, modern chemical plants are becoming increasingly complex, to an extent that cannot be effectively managed by existing process modelling and control techniques.
The aims of this research are to assess the effects of immune modulation by inducing immune tolerance and manipulating regulatory T cells on pain behaviours following nervous system injury.
The actin cytoskeleton has long been known to be a key regulator of cell proliferation linking biochemical sensing of the environment with cell cycle progression.
The proposed project aims to develop strategic and integrated approaches to address the impact of variability in water characteristics caused by climate change on Australian water treatment processes (WTPs).
Fouling reduces throughput and productivity of membrane systems and as such increases operating costs and reduces profitability of water treatment industries. This work aims to reduce fouling by reducing the amount of solute at a membrane surface by destabilizing flow control.
We have recently built the first protein 'methylation network' for any species. This project will study the dynamics of this network during the cell cycle and will identify protein complexes which have methylation-associated interactions.
The aim of the project is to reveal the mechanisms of the stabilisation of lifted jet flames in hot oxidiser. Such flames occur in several important combustion devices, notably diesel engines.
The project will contribute fundamental knowledge towards the development of the clean and highly efficient homogeneous charge compression ignition engine concept.