By Dr Jason Ciril Kovacic

Journal articles

Kovacic JC; Lee P; Karajgikar R; Baber U; Narechania B; Suleman J; Moreno PR; Sharma SK; Kini AS, 2012, 'Safety of temporary and permanent suspension of antiplatelet therapy after drug eluting stent implantation in contemporary "real-world" practice', Journal of Interventional Cardiology, 25, pp. 482 - 492, http://dx.doi.org/10.1111/j.1540-8183.2012.00746.x

Purushothaman KR; Purushothaman M; Levy AP; Lento PA; Evrard S; Kovacic JC; Briley-Saebo KC; Tsimikas S; Witztum JL; Krishnan P; Kini A; Fayad ZA; Fuster V; Sharma SK; Moreno PR, 2012, 'Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: Possible implications for plaque progression in human atherosclerosis', Journal of the American College of Cardiology, 60, pp. 112 - 119, http://dx.doi.org/10.1016/j.jacc.2012.04.011

Chirumamilla AP; Maehara A; Mintz GS; Mehran R; Kanwal S; Weisz G; Hassanin A; Hakim D; Guo N; Baber U; Pyo R; Moses JW; Fahy M; Kovacic JC; Dangas GD, 2012, 'High platelet reactivity on clopidogrel therapy correlates with increased coronary atherosclerosis and calcification: A volumetric intravascular ultrasound study', Jacc Cardiovascular Imaging, 5, pp. 540 - 549, http://dx.doi.org/10.1016/j.jcmg.2011.12.019

Kovacic JC; Mercader N; Torres M; Boehm M; Fuster V, 2012, 'Epithelial-to-mesenchymal and endothelial-to-mesenchymal transition from cardiovascular development to disease', Circulation, 125, pp. 1795 - 1808, http://dx.doi.org/10.1161/CIRCULATIONAHA.111.040352

Kovacic JC; Sharma SK; Kini AS, 2012, 'Bilateral coronary ostial stenoses post-bentall procedure causing hemodynamic collapse and requiring mechanical assist device placement: Successful intervention using the Szabo technique', Catheterization and Cardiovascular Interventions, 79, pp. 801 - 804, http://dx.doi.org/10.1002/ccd.23132

Evrard SM; Daudigier C; Mauge L; Israël-Biet D; Guerin CL; Bieche I; Kovacic JC; Fischer AM; Gaussem P; Smadja DM, 2012, 'The profibrotic cytokine transforming growth factor-β1 increases endothelial progenitor cell angiogenic properties', Journal of Thrombosis and Haemostasis, 10, pp. 670 - 679, http://dx.doi.org/10.1111/j.1538-7836.2012.04644.x

Kovacic JC; Lee P; Baber U; Karajgikar R; Evrard SM; Moreno P; Mehran R; Fuster V; Dangas G; Sharma SK; Kini AS, 2012, 'Inverse relationship between body mass index and coronary artery calcification in patients with clinically significant coronary lesions', Atherosclerosis, 221, pp. 176 - 182, http://dx.doi.org/10.1016/j.atherosclerosis.2011.11.020

Kovacic JC; Mehran R; Karajgikar R; Baber U; Suleman J; Kim MC; Krishnan P; Dangas G; Sharma SK; Kini A, 2012, 'Female gender and mortality after percutaneous coronary intervention: results from a large registry.', Catheterization and Cardiovascular Interventions Official Journal of the Society for Cardiac Angiography Interventions, 80, pp. 514 - 521, http://dx.doi.org/10.1002/ccd.23338

Kovacic JC; Fuster V, 2012, 'Vascular calcification, diabetes, and cardiovascular disease: Connecting the dots', Jacc Cardiovascular Imaging, 5, pp. 367 - 369, http://dx.doi.org/10.1016/j.jcmg.2012.02.006

Hadri L; Bobe R; Lopez JJ; Turnbull IC; Kovacic JC; Karakikes I; Kranias E; Hajjar RJ; Larissa L, 2012, 'Abstract 468: The Role of Ca2+/PKA Signaling Enhancer Protein Phosphatase Inhibitor 1 in the Control of Ca2+ Cycling and Signaling in VSMCs', Arteriosclerosis Thrombosis and Vascular Biology, 32, http://dx.doi.org/10.1161/atvb.32.suppl_1.a468

Baber U; Zafar MU; uribarri J; Murphy B; Khan A; Akter F; Bander J; Muntner P; Kovacic JC; Yu J; Theodoropoulos K; Mehran R; Dangas G; Kini A; Sharma S; Fuster V; Badimon J, 2012, 'PHYSIOLOGIC IMPACT OF CHRONIC KIDNEY DISEASE ON WHOLE BLOOD CLOT KINETICS AND STRENGTH', Journal of the American College of Cardiology, 59, pp. e2096, http://dx.doi.org/10.1016/s0735-1097(12)62097-x

Baber U; Purushothaman K-R; Krishnan P; Purushothaman M; Kovacic JC; Mehran R; Dangas G; Kini A; Sharma S; Moreno P, 2012, 'SYNERGISTIC IMPACT OF CHRONIC KIDNEY DISEASE AND DIABETES MELLITUS ON PERIPHERAL VASCULAR ATHEROSCLEROTIC PLAQUE NEOVASCULARIZATION AND INFLAMMATION', Journal of the American College of Cardiology, 59, pp. e2094, http://dx.doi.org/10.1016/s0735-1097(12)62095-6

Hadri L; Regis B; Lopez JJ; Turnbull IC; Kovacic JC; Karakikes I; Kranias E; Hajjar RJ; Lipskaia L, 2012, 'The role of cAMP/PKA signaling enhancer Protein Phosphatase Inhibitor 1 (I‐1) in the control of Ca2+ cycling and signaling in VSMCs', The FASEB Journal, 26, pp. lb477 - lb477, http://dx.doi.org/10.1096/fasebj.26.1_supplement.lb477

Baber U; Kovacic J; Kini AS; Sharma SK; Dangas G; Mehran R, 2011, 'How serious a problem is bleeding in patients with acute coronary syndromes?', Current Cardiology Reports, 13, pp. 312 - 319, http://dx.doi.org/10.1007/s11886-011-0192-3

Kovacic JC; Randolph GJ, 2011, 'Vascular calcification: Harder than it looks', Arteriosclerosis Thrombosis and Vascular Biology, 31, pp. 1249 - 1250, http://dx.doi.org/10.1161/ATVBAHA.111.227868

Kovacic JC; Moreno P; Nabel EG; Hachinski V; Fuster V, 2011, 'Cellular senescence, vascular disease, and aging: Part 2 of a 2-part review: Clinical vascular disease in the elderly', Circulation, 123, pp. 1900 - 1910, http://dx.doi.org/10.1161/CIRCULATIONAHA.110.009118

Rubboli A; Kovacic JC; Mehran R; Lip GYH, 2011, 'Coronary stent implantation in patients committed to long-term oral anticoagulation therapy: Successfully navigating the treatment options', Chest, 139, pp. 981 - 987, http://dx.doi.org/10.1378/chest.10-2719

Kovacic JC; Moreno P; Hachinski V; Nabel EG; Fuster V, 2011, 'Cellular senescence, vascular disease, and aging: Part 1 of a 2-part review', Circulation, 123, pp. 1650 - 1660, http://dx.doi.org/10.1161/CIRCULATIONAHA.110.007021

Kovacic JC; Kini A, 2011, 'Inferior outcomes in percutaneous coronary interventions: Narrowing the gap between men and women', Interventional Cardiology, 3, pp. 119 - 121, http://dx.doi.org/10.2217/ica.11.17

Kovacic JC; Karajgikar R; Krishnan P; Kim M; Suleman J; Kini A; Sharma SK, 2011, 'EQUIVALENT OUTCOMES WITH SECOND VERSUS FIRST GENERATION DRUG ELUTING CORONARY STENTS WHEN USED IN HEAVILY CALCIFIED LESIONS REQUIRING ROTATIONAL ATHERECTOMY', Journal of the American College of Cardiology, 57, pp. e1885, http://dx.doi.org/10.1016/s0735-1097(11)61885-8

Kovacic JC; Mehran R; Dangas G; Claessen B; Parise H; Fahy M; Lansky AJ; Witzenbichler B; Grines CL; Guagliumi G; Kornowski R; Wöhrle J; Dudek D; Weisz G; Stone GW, 2011, 'IMPACT OF ASPIRIN DOSE ON LONG TERM CLINICAL OUTCOMES AFTER STENTING FOR ACUTE MYOCARDIAL INFARCTION: 3-YEAR FOLLOW-UP DATA FROM THE HORIZONS-AMI TRIAL', Journal of the American College of Cardiology, 57, pp. e1633, http://dx.doi.org/10.1016/s0735-1097(11)61633-1

Baber U; Mehran R; Sharma SK; Brar S; Yu J; Suh J-W; Kim H-S; Park S-J; Kastrati A; de Waha A; Krishnan P; Moreno P; Sweeny J; Kim MC; Suleman J; Pyo R; Wiley J; Kovacic J; Kini AS; Dangas GD, 2011, 'Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials.', Journal of the American College of Cardiology, 58, pp. 1569 - 1577, http://dx.doi.org/10.1016/j.jacc.2011.06.049

Limaye AM; Patel R; Chandela S; Lee P; Trost B; Karajgikar R; Kovacic JC; Pyo RT; Sweeney J; Suleman J; Kim M; Krishnan P; Moreno P; Kini A; Sharma SK, 2011, 'THE CLINICALLY BASED NEW YORK STATE RISK SCORE IS SUPERIOR TO THE ANGIOGRAPHICALLY BASED SYNTAX RISK SCORE FOR PREDICTING PATIENT OUTCOMES AFTER PCI', Journal of the American College of Cardiology, 57, pp. e1949, http://dx.doi.org/10.1016/s0735-1097(11)61949-9

Kovacic JC; Khanna D; Kaplish D; Karajgikar R; Sharma SK; Kini A, 2010, 'Safety and efficacy of alcohol septal ablation in patients with symptomatic concentric left ventricular hypertrophy and outflow tract obstruction', Journal of Invasive Cardiology, 22, pp. 586 - 591

Iwasaki H; Kovacic JC; Olive M; Beers JK; Yoshimoto T; Crook MF; Tonelli LH; Nabel EG, 2010, 'Disruption of protein arginine N-methyltransferase 2 regulates leptin signaling and produces leanness in vivo through loss of STAT3 methylation', Circulation Research, 107, pp. 992 - 1001, http://dx.doi.org/10.1161/CIRCRESAHA.110.225326

Chih SS; Macdonald P; McCrohon JA; Ma D; John M; Law M; Feneley MP; Herbert A; Kovacic JC; Graham RM, 2010, 'GRANULOCYTE-COLONY STIMULATING FACTOR IN ANGINA PATIENTS WITH ISCHAEMIC HEART DIESASE TO STIMULATE NEOVASCULARISATION (GAIN II TRIAL)', JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 55

Kovacic JC; Gupta R; Lee AC; Ma M; Fang F; Tolbert CN; Walts AD; Beltran LE; San H; Chen G; St Hilaire C; Boehm M, 2010, 'Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice', Journal of Clinical Investigation, 120, pp. 303 - 314, http://dx.doi.org/10.1172/JCI40364

Ma M; Ding S; Lundqvist A; San H; Fang F; Konoplyannikov M; Berry C; Beltran LE; Chen G; Kovacic JC; Boehm M, 2010, 'Major histocompatibility complex-I expression on embryonic stem cell-derived vascular progenitor cells is critical for syngeneic transplant survival', Stem Cells, 28, pp. 1465 - 1475, http://dx.doi.org/10.1002/stem.475

Kovacic JC; Gupta R; Lee AC; Ma M; Fang F; Tolbert CN; Walts AD; Beltran LE; San H; Chen G; Boehm M, 2009, 'Abstract 5275: STAT3-dependent Acute RANTES Production in Vascular Smooth Muscle Cells Modulates Inflammation Following Arterial Injury', Circulation, 120, http://dx.doi.org/10.1161/circ.120.suppl_18.s1078-a

Kovacic JC; Macdonald P; Feneley MP; Graham RM, 2009, 'Granulocyte-colony stimulating factor in refractory ischemic heart disease: Throwing stones from glass houses', American Heart Journal, 157, pp. e39, http://dx.doi.org/10.1016/j.ahj.2009.02.009

Kovacic JC; Boehm M, 2009, 'Resident vascular progenitor cells: An emerging role for non-terminally differentiated vessel-resident cells in vascular biology', Stem Cell Research, 2, pp. 2 - 15, http://dx.doi.org/10.1016/j.scr.2008.05.005

Kovacic J; Macdonald PS; Feneley MP; Graham RM, 2009, 'Granulocyte-colony stimulating factor in refractory ischemic heart disease: Throwing stones from glass houses', American Heart Journal, 157, pp. e39, http://dx.doi.org/10.1016/j.aucc.2009.06.001

Wragg A; Mellad JA; Beltran LE; Konoplyannikov M; San H; Boozer S; Deans RJ; Mathur A; Lederman RJ; Kovacic JC; Boehm M, 2008, 'VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism', Journal of Molecular Medicine, 86, pp. 1221 - 1232, http://dx.doi.org/10.1007/s00109-008-0390-7

Olive M; Mellad JA; Beltran LE; Ma M; Cimato T; Noguchi AC; San H; Childs R; Kovacic JC; Boehm M, 2008, 'p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice', Journal of Clinical Investigation, 118, pp. 2050 - 2061, http://dx.doi.org/10.1172/JCI31244

Kovacic JC; Moore JJ; Herbert AD; Ma DD; Boehm M; Graham RM, 2008, 'Endothelial progenitor cells, angioblasts, and angiogenesis - Old terms reconsidered from a current perspective', Trends in Cardiovascular Medicine, 18, pp. 45 - 51

Matthews J; Pitney M; Kovacic J; Lindeman R; Loh E; Jepson N; Cranney G; Ooi S-Y, 2008, 'Feasibility and Safety of Erythropoietin (EPO) Administration in Patients with Acute Myocardial Infarction to Improve Cardiac Function and Remodelling: Pilot Study', Heart Lung and Circulation, 17, pp. s173, http://dx.doi.org/10.1016/j.hlc.2008.05.412

Kovacic JC; Macdonald P; Feneley MP; Muller DWM; Freund J; Dodds A; Milliken S; Tao H; Itescu S; Moore J; Ma D; Graham RM, 2008, 'Safety and efficacy of consecutive cycles of granulocyte-colony stimulating factor, and an intracoronary CD133+ cell infusion in patients with chronic refractory ischemic heart disease: the G-CSF in angina patients with IHD to stimulate neovascularization (GAIN I) trial.', Am Heart J, 156, pp. 954 - 963, http://dx.doi.org/10.1016/j.ahj.2008.04.034

Kovacic JC; Harvey RP; Dimmeler S, 2007, 'Cardiovascular Regenerative Medicine: Digging In for the Long Haul', Cell Stem Cell, 1, pp. 628 - 633, http://dx.doi.org/10.1016/j.stem.2007.11.011

Kovacic JC; Macdonald P; Feneley MP; Muller DW; Ma D; Tao H; Freund J; Milliken S; Dodds A; Moore J; Itescu S; Graham RM, 2007, 'Abstract 2669: The Use of Granulocyte-Colony Stimulating Factor in Angina Patients to Stimulate Neovascularization: the GAIN I study', Circulation, 116, http://dx.doi.org/10.1161/circ.116.suppl_16.ii_591-d

Kovacic JC; Muller DW; Graham RM, 2007, 'Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease', Journal of Molecular and Cellular Cardiology, 42, pp. 19 - 33

Kovacic JC; Ma DD; Tao H; Herbert AD; Moore JJ; Graham RM, 2007, 'Phenotypic characterization of CD133+cells suggests a potent hemangioblast population', Circulation Research, 101, pp. E55 - E56

Kovacic JC; Macdonald PS; Freund J; Rasko J; Allan RM; Fernandes VB; Ma DD; Moore JJ; Graham RM, 2007, 'Profound thrombocytopenia related to G-CSF', American Journal of Hematology, 82, pp. 229 - 230

Mallon PW; Miller JE; Kovacic JC; Kent-Hughes J; Norris RP; Samaras K; Feneley MP; Cooper DA; Carr AD, 2006, 'Effect of pravastatin on body composition and markers of cardiovascular disease in HIV-infected men - a randomized, placebo-controlled study', AIDS, 20, pp. 1003 - 1010

Kovacic JC; Roy PR; Baron D; Muller DW, 2006, 'Staged carotid artery stenting and coronary artery bypass graft surgery: Initial results from a single center', Catheterization and Cardiovascular Interventions, 67, pp. 142 - 148

D.F. D; Kovacic JC; Dodds A; Tao H; McDonald P; Feneley MP; Muller DW; Fruend J; Milliken S; Moore J; Itescu S; Graham RM, 2005, 'Granulocyte-Colony Stimulating Factor Decreases Angina and Improves Exercise Capacity in Patients with Chronic Refractory ‘No Option' Ischemic Heart Disease.', Blood, 106, pp. 4215, http://dx.doi.org/10.1182/blood.v106.11.4215.4215

Kovacic JC; Graham RM, 2005, 'Are improvements in cardiac function due to stem cell uptake and engraftment?', American Journal of Cardiology, 95, pp. 159, http://dx.doi.org/10.1016/j.amjcard.2004.07.138

Mallon PW; Miller JM; Kovacic JC; Kent-Hughes J; Norris RP; Samaras K; Feneley MP; Cooper DA; Carr AD, 2005, 'Changes in body composition and cardiovascular measures in hypercholesterolaemic HIV-infected men treated with pravastatin: a randomized, placebo-controlled study', Antiviral Therapy, 10, pp. L15 - L16

Kovacic JC, 2005, 'Further aspects of anemia, heart failure, and erythropoietin', Journal of the American College of Cardiology, 45, pp. 1549 - 1550

Ma DD; Kovacic JC; Dodds AJ; Tao H; Mcdonald PS; Feneley MP; Muller DW; Fruend J; Milliken ST; Moore JJ; Itescu S; Graham RM, 2005, 'Granulocyte-colony stimulating factor decreases angina and improves exercise capacity in patients with chronic refractory `no option` ischemic heart disease', Blood, 106, pp. 134B - 134B

Kovacic JC; Martin A; Carey DL; Wand HC; Mallon PW; Feneley MP; Emery S; Cooper DA; Carr AD, 2005, 'Influence of rosiglitazone on flow-mediated dilation and other markers of cardiovascular risk in HIV-infected patients with lipoatrophy', Antiviral Therapy, 10, pp. 135 - 143

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