By Dr Jason Ciril Kovacic

Journal articles

Kalkman DN; Aquino M; Baber U; Vogel B; Sorrentino S; Guedeney P; Sweeny J; Kovacic J; Shah S; Vijay P; Barman N; Sharma S; Kini A; Dangas G; Mehran R, 2018, 'P6435Impact of persistent high C-reactive protein levels on all-cause mortality in patients after percutaneous coronary interventions', European Heart Journal, 39, pp. ehy566.p6435, http://dx.doi.org/10.1093/eurheartj/ehy566.p6435

Kovacic JC, 2018, 'The Endothelial–Metabolic Axis: A Novel Cardiometabolic Disease Target', Trends in Endocrinology and Metabolism, 29, pp. 527 - 529, http://dx.doi.org/10.1016/j.tem.2018.03.015

Michelis KC; Nomura-Kitabayashi A; Lecce L; Franzén O; Koplev S; Xu Y; Santini MP; D'Escamard V; Lee JTL; Fuster V; Hajjar R; Reddy RC; Chikwe J; Stelzer P; Filsoufi F; Stewart A; Anyanwu A; Björkegren JLM; Kovacic JC, 2018, 'CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Human Medium- and Large-Sized Arteries', Stem Cell Reports, 11, pp. 242 - 257, http://dx.doi.org/10.1016/j.stemcr.2018.06.001

Sherifi I; Omar AMS; Varghese M; Weiner M; Anyanwu A; Kovacic JC; Sharma S; Kini A; Sengupta PP, 2018, 'Comparison of transesophageal and transthoracic echocardiography under moderate sedation for guiding transcatheter aortic valve replacement', Echo Research and Practice, 5, pp. 79 - 87, http://dx.doi.org/10.1530/ERP-17-0080

Copeland-Halperin RS; Baber U; Aquino M; Rajamanickam A; Roy S; Hasan C; Barman N; Kovacic JC; Moreno P; Krishnan P; Sweeny JM; Mehran R; Dangas G; Kini AS; Sharma SK, 2018, 'Prevalence, correlates, and impact of coronary calcification on adverse events following PCI with newer-generation DES: Findings from a large multiethnic registry', Catheterization and Cardiovascular Interventions, 91, pp. 859 - 866, http://dx.doi.org/10.1002/ccd.27204

Watanabe S; Fish K; Kovacic JC; Bikou O; Leonardson L; Nomoto K; Aguero J; Kapur NK; Hajjar RJ; Ishikawa K, 2018, 'Left ventricular unloading using an impella CP improves coronary flow and infarct zone perfusion in ischemic heart failure', Journal of the American Heart Association, 7, http://dx.doi.org/10.1161/JAHA.117.006462

Franzén O; Ermel R; Sukhavasi K; Jain R; Jain A; Betsholtz C; Giannarelli C; Kovacic JC; Ruusalepp A; Skogsberg J; Hao K; Schadt EE; Björkegren JLM, 2018, 'Global analysis of A-to-I RNA editing reveals association with common disease variants', Peerj, 2018, http://dx.doi.org/10.7717/peerj.4466

Dweck MR; Abgral R; Trivieri MG; Robson PM; Karakatsanis N; Mani V; Palmisano A; Miller MA; Lala A; Chang HL; Sanz J; Contreras J; Narula J; Fuster V; Padilla M; Fayad ZA; Kovacic JC, 2018, 'Hybrid Magnetic Resonance Imaging and Positron Emission Tomography With Fluorodeoxyglucose to Diagnose Active Cardiac Sarcoidosis', Jacc Cardiovascular Imaging, 11, pp. 94 - 107, http://dx.doi.org/10.1016/j.jcmg.2017.02.021

Khan AA; Kovacic JC; Engstrom K; Stewart A; Anyanwu A; Basnet S; Aquino M; Baber U; Garcia L; Gidwani U; Dangas G; Kini A; Sharma S, 2018, 'Comparison of Transaortic and Subclavian Approaches for Transcatheter Aortic Valve Replacement in Patients with No Transfemoral Access Options*', Structural Heart, 2, pp. 463 - 468, http://dx.doi.org/10.1080/24748706.2018.1497237

Hajjar RJ; Ishikawa K; Kovacic JC; Fuster V, 2017, 'Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai Translational Mission', Circulation Research, 121, pp. 1316 - 1319, http://dx.doi.org/10.1161/CIRCRESAHA.117.311372

Pena J; Vengrenyuk Y; Kezbor S; Yoshimura T; Kovacic JC; Sharma SK; Baber U; Kini AS; Narula J; Moreno PR, 2017, 'Increased Lipid Length, Macrophage Infiltration, and Neovascularization in Coronary Atheroma From Patients With Chronic Kidney Disease', Jacc Cardiovascular Imaging, 10, pp. 1524 - 1526, http://dx.doi.org/10.1016/j.jcmg.2017.01.019

Chandrasekhar J; Sartori S; Baber U; Shah S; Rabieihashemi S; Vogel B; Farhan S; Ge Z; Sorrentino S; Sharma M; Qadeer A; Demopoulos A; Snyder C; Moazzami K; Sudyn A; Moreno P; Kovacic J; Sweeney J; Krishnan P; Barman N; Dangas G; Mehran R; Kini A; Sharma S, 2017, 'Abstract 21306: Impact of Insulin Treated Diabetes Mellitus on 1 Year Outcomes After Contemporary PCI', Circulation, 136, http://dx.doi.org/10.1161/circ.136.suppl_1.21306

Robson PM; Dweck MR; Trivieri MG; Abgral R; Karakatsanis NA; Contreras J; Gidwani U; Narula JP; Fuster V; Kovacic JC; Fayad ZA, 2017, 'Coronary Artery PET/MR Imaging: Feasibility, Limitations, and Solutions', Jacc Cardiovascular Imaging, 10, pp. 1103 - 1112, http://dx.doi.org/10.1016/j.jcmg.2016.09.029

Vogel B; Chandrasekhar J; Farhan S; Sartori S; Giustino G; Snyder C; Kovacic J; Moreno P; Barman N; Sweeny J; Vijay P; Dangas G; Mehran R; Kini A; Sharma S, 2017, '2927Sex-related differences in patients undergoing complex coronary interventions in the era of 2nd generation DES', European Heart Journal, 38, pp. ehx504.2927, http://dx.doi.org/10.1093/eurheartj/ehx504.2927

Sorrentino S; Baber U; Chandrasekhar Y; Zhen G; Sartori S; Kovacic J; Moreno PR; Barman N; Sweeney J; Vijay P; Giustino G; Dangas G; Mehran R; Kini A; Sharma S, 2017, 'P1389Impact of peripheral arterial disease on provision of discharge pharmacotherapy and longitudinal outcomes in patients with stable angina undergoing percutaneous coronary interventions', European Heart Journal, 38, pp. ehx502.p1389, http://dx.doi.org/10.1093/eurheartj/ehx502.p1389

Vogel B; Baber U; Chandrasekhar J; Sartori S; Farhan S; Sorrentino S; Kovacic J; Moreno P; Barman N; Sweeny J; Shah S; Dangas G; Mehran R; Kini A; Sharma S, 2017, 'P2069Multivessel PCI versus culprit-vessel only PCI in patients with acute myocardial infarction and multivessel disease', European Heart Journal, 38, pp. ehx502.p2069, http://dx.doi.org/10.1093/eurheartj/ehx502.p2069

Farhan S; Vogel B; Baber U; Sartori S; Sorrentino S; Nitin B; Vijay P; Kovacic J; Sweeny J; Moreno P; Giustino G; Dangas GD; Mehran R; Kini A; Sharma S, 2017, 'P2331Association between serum osmolality and acute kidney injury after percutaneous coronary intervention: a simple tool for acute kidney injury prediction', European Heart Journal, 38, pp. ehx502.p2331, http://dx.doi.org/10.1093/eurheartj/ehx502.p2331

Sharma M; Baber U; Sorrentino S; Chandrasekhar J; Sartori S; Kovacic J; Moreno PR; Barman N; Sweeny J; Vijay P; Giustino G; Dangas G; Mehran R; Kini A; Sharma S, 2017, 'P6114Characteristics and clinical outcomes in patients undergoing PCI by levels of high-density lipoproteins', European Heart Journal, 38, pp. ehx493.p6114, http://dx.doi.org/10.1093/eurheartj/ehx493.p6114

Sack MN; Fyhrquist FY; Saijonmaa OJ; Fuster V; Kovacic JC, 2017, 'Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of a 3-Part Series', Journal of the American College of Cardiology, 70, pp. 196 - 211, http://dx.doi.org/10.1016/j.jacc.2017.05.034

Münzel T; Camici GG; Maack C; Bonetti NR; Fuster V; Kovacic JC, 2017, 'Impact of Oxidative Stress on the Heart and Vasculature: Part 2 of a 3-Part Series', Journal of the American College of Cardiology, 70, pp. 212 - 229, http://dx.doi.org/10.1016/j.jacc.2017.05.035

Niemann B; Rohrbach S; Miller MR; Newby DE; Fuster V; Kovacic JC, 2017, 'Oxidative Stress and Cardiovascular Risk: Obesity, Diabetes, Smoking, and Pollution: Part 3 of a 3-Part Series', Journal of the American College of Cardiology, 70, pp. 230 - 251, http://dx.doi.org/10.1016/j.jacc.2017.05.043

Johnson KW; Shameer K; Glicksberg BS; Readhead B; Sengupta PP; Björkegren JLM; Kovacic JC; Dudley JT, 2017, 'Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine', Jacc Basic to Translational Science, 2, pp. 311 - 327, http://dx.doi.org/10.1016/j.jacbts.2016.11.010

Krishnamoorthy P; Vengrenyuk Y; Ueda H; Yoshimura T; Pena J; Motoyama S; Baber U; Hasan C; Kesanakurthy S; Sweeny JM; Sharma SK; Narula J; Kovacic JC; Kini AS, 2017, 'Three-dimensional volumetric assessment of coronary artery calcification in patients with stable coronary artery disease by OCT', Eurointervention, 13, pp. 312 - 319, http://dx.doi.org/10.4244/EIJ-D-16-00139

Abgral R; Dweck MR; Trivieri MG; Robson PM; Karakatsanis N; Mani V; Padilla M; Miller M; Lala A; Sanz J; Narula J; Fuster V; Contreras J; Kovacic JC; Fayad ZA, 2017, 'Clinical Utility of Combined FDG-PET/MR to Assess Myocardial Disease', Jacc Cardiovascular Imaging, 10, pp. 594 - 597, http://dx.doi.org/10.1016/j.jcmg.2016.02.029

Bansilal S; Vedanthan R; Kovacic JC; Soto AV; Latina J; Björkegren JL; Jaslow R; Santana M; Sartori S; Giannarelli C; Mani V; Hajjar R; Schadt E; Kasarskis A; Fayad ZA; Fuster V, 2017, 'Rationale and Design of Family-Based Approach in a Minority Community Integrating Systems–Biology for Promotion of Health (FAMILIA)', American Heart Journal, 187, pp. 170 - 181, http://dx.doi.org/10.1016/j.ahj.2017.02.020

Farhan S; Baber U; Vogel B; Aquino M; Chandrasekhar J; Faggioni M; Giustino G; Kautzky-Willer A; Sweeny J; Shah S; Vijay P; Barman N; Moreno P; Kovacic J; Dangas G; Kini A; Mehran R; Sharma S, 2017, 'Impact of Diabetes Mellitus on Ischemic Events in Men and Women After Percutaneous Coronary Intervention', American Journal of Cardiology, 119, pp. 1166 - 1172, http://dx.doi.org/10.1016/j.amjcard.2016.12.035

Krishnan P; Tarricone A; Purushothaman KR; Purushothaman M; Vasquez M; Kovacic J; Baber U; Kapur V; Gujja K; Kini A; Sharma S, 2017, 'An Algorithm for the Use of Embolic Protection During Atherectomy for Femoral Popliteal Lesions', Jacc Cardiovascular Interventions, 10, pp. 403 - 410, http://dx.doi.org/10.1016/j.jcin.2016.12.014

Kovacic JC, 2017, 'Unraveling the Complex Genetics of Coronary Artery Disease', Journal of the American College of Cardiology, 69, pp. 837 - 840, http://dx.doi.org/10.1016/j.jacc.2016.12.007

Evrard SM; Lecce L; Michelis KC; Nomura-Kitabayashi A; Pandey G; Purushothaman KR; d'Escamard V; Li JR; Hadri L; Fujitani K; Moreno PR; Benard L; Rimmele P; Cohain A; Mecham B; Randolph GJ; Nabel EG; Hajjar R; Fuster V; Boehm M; Kovacic JC, 2017, 'Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability', Nature Communications, 8, pp. 14710, http://dx.doi.org/10.1038/ncomms14710

Kini AS; Vengrenyuk Y; Shameer K; Maehara A; Purushothaman M; Yoshimura T; Matsumura M; Aquino M; Haider N; Johnson KW; Readhead B; Kidd BA; Feig JE; Krishnan P; Sweeny J; Milind M; Moreno P; Mehran R; Kovacic JC; Baber U; Dudley JT; Narula J; Sharma S, 2017, 'Intracoronary Imaging, Cholesterol Efflux, and Transcriptomes After Intensive Statin Treatment: The YELLOW II Study', Journal of the American College of Cardiology, 69, pp. 628 - 640, http://dx.doi.org/10.1016/j.jacc.2016.10.029

Kini AS; Vengrenyuk Y; Pena J; Yoshimura T; Panwar SR; Motoyama S; Kezbor S; Hasan CM; Palkhiwala S; Kovacic JC; Moreno P; Baber U; Mehran R; Narula J; Sharma SK, 2017, 'Plaque morphology predictors of side branch occlusion after provisional stenting in coronary bifurcation lesion: Results of optical coherence tomography bifurcation study (ORBID)', Catheterization and Cardiovascular Interventions, 89, pp. 259 - 268, http://dx.doi.org/10.1002/ccd.26524

Theodoropoulos K; Mennuni MG; Dangas GD; Meelu OA; Bansilal S; Baber U; Sartori S; Kovacic JC; Moreno PR; Sharma SK; Mehran R; Kini AS, 2016, 'Resistant in-stent restenosis in the drug eluting stent era', Catheterization and Cardiovascular Interventions, 88, pp. 777 - 785, http://dx.doi.org/10.1002/ccd.26559

Kiando SR; Tucker NR; Castro-Vega LJ; Katz A; D’Escamard V; Tréard C; Fraher D; Albuisson J; Kadian-Dodov D; Ye Z; Austin E; Yang ML; Hunker K; Barlassina C; Cusi D; Galan P; Empana JP; Jouven X; Gimenez-Roqueplo AP; Bruneval P; Hyun Kim ES; Olin JW; Gornik HL; Azizi M; Plouin PF; Ellinor PT; Kullo IJ; Milan DJ; Ganesh SK; Boutouyrie P; Kovacic JC; Jeunemaitre X; Bouatia-Naji N, 2016, 'PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance', Plos Genetics, 12, http://dx.doi.org/10.1371/journal.pgen.1006367

Franzén O; Ermel R; Cohain A; Akers NK; Di Narzo A; Talukdar HA; Foroughi-Asl H; Giambartolomei C; Fullard JF; Sukhavasi K; Köks S; Gan LM; Giannarelli C; Kovacic JC; Betsholtz C; Losic B; Michoel T; Hao K; Roussos P; Skogsberg J; Ruusalepp A; Schadt EE; Björkegren JLM, 2016, 'Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases', Science, 353, pp. 827 - 830, http://dx.doi.org/10.1126/science.aad6970

Evrard SM; Lecce L; Michelis KC; Nomura-Kitabayashi A; Pandey G; Purushothaman KR; D'Escamard V; Li JR; Hadri L; Fujitani K; Moreno PR; Benard L; Rimmele P; Cohain A; Mecham B; Randolph GJ; Nabel EG; Hajjar R; Fuster V; Boehm M; Kovacic JC, 2016, 'Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability', Nature Communications, 7, http://dx.doi.org/10.1038/ncomms11853

Mosley GE; Beckerman W; Kovacic JC; Kini AS; Sharma SK; Tadros RO, 2016, 'Management of complete iliofemoral artery avulsion with a hybrid technique', Journal of Vascular Surgery Cases and Innovative Techniques, 2, pp. 37 - 39, http://dx.doi.org/10.1016/j.jvsc.2016.03.002

Santini MP; Forte E; Harvey RP; Kovacic JC, 2016, 'Developmental origin and lineage plasticity of endogenous cardiac stem cells', Development Cambridge, 143, pp. 1242 - 1258, http://dx.doi.org/10.1242/dev.111591

Vedanthan R; Bansilal S; Soto AV; Kovacic JC; Latina J; Jaslow R; Santana M; Gorga E; Kasarskis A; Hajjar R; Schadt EE; Björkegren JL; Fayad ZA; Fuster V, 2016, 'Family-Based Approaches to Cardiovascular Health Promotion', Journal of the American College of Cardiology, 67, pp. 1725 - 1737, http://dx.doi.org/10.1016/j.jacc.2016.01.036

Jeong D; Yang DK; Kho C; Oh JG; Lee A; Chen J; Liang L; Mitsuyama S; D'Escamard V; Kovacic JC; Hajjar RJ; Lee MA; Li Y; Hong G; Song MH; Park WJ; LaRocca TJ; Kwak TH, 2016, 'Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis', Journal of the American College of Cardiology, 67, pp. 1556 - 1568, http://dx.doi.org/10.1016/j.jacc.2016.01.030

Talukdar HA; Foroughi Asl H; Jain RK; Ermel R; Ruusalepp A; Franzén O; Kidd BA; Readhead B; Giannarelli C; Kovacic JC; Ivert T; Dudley JT; Civelek M; Lusis AJ; Schadt EE; Skogsberg J; Michoel T; Björkegren JLM, 2016, 'Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease', Cell Systems, 2, pp. 196 - 208, http://dx.doi.org/10.1016/j.cels.2016.02.002

Wiley BM; Kovacic JC; Basnet S; Makoto A; Chaudhry FA; Kini AS; Sharma SK; Sengupta PP, 2016, 'Intraprocedural TAVR Annulus Sizing Using 3D TEE and the “Turnaround Rule”', Jacc Cardiovascular Imaging, 9, pp. 213 - 215, http://dx.doi.org/10.1016/j.jcmg.2015.02.018

, 2016, 'Correction', Journal of the American College of Cardiology, 67, pp. 2809, http://dx.doi.org/10.1016/j.jacc.2016.04.014

Kiando S; Tucker N; Katz A; Tréard C; Desca-Mard V; Castro-Vega L; Barlasina C; Cusi D; Galan P; Empana J; Olin J; Gornik H; Plouin P; Kullo I; Milan D; Ganesh S; Boutouyrie P; Kovacic J; Jeunemaitre X; Bouatia-Naji N, 2015, 'CO-43: Genetic study identifies common variation in phactr1 to associate with fibromuscular dysplasia', Annales De Cardiologie Et D Angeiologie, 64, pp. S20, http://dx.doi.org/10.1016/S0003-3928(16)30043-9

Krishnan P; K-Raman P; Purushothaman M; Kovacic JC; Baber U; Tarricone A; Vasquez M; Wiley J; Kini A; Sharma SK; Fuster V; Moreno PR, 2015, 'Abstract 15275: Altered Extracellular Matrix Proteoglycan- Decorin, Collagens and Elastin Deposition May Enhance Atherosclerosis in Human Peripheral Artery Disease: Implication of Morphological Predictors in Restenotic Plaque Progression', Circulation, 132, http://dx.doi.org/10.1161/circ.132.suppl_3.15275

Kiando SR; Tucker N; Katz A; Tréard C; D’Escamard V; Castro-Vega LJ; Ye Z; Smith CY; Austin E; Barlasina C; Cusi D; Galan P; Empana J-P; Jouven X; Brunval P; Olin JW; Gornik H; Plouin P-F; Kullo IJ; Milan DJ; Ganesh SK; Boutouyrie P; Kovacic J; Jeunemaitre X; Bouatia-Naji N, 2015, 'Abstract 15370: Genetic Study Identifies Common Variation in PHACTR1 to Associate With Fibromuscular Dysplasia (Best of Basic Science Abstract)', Circulation, 132, http://dx.doi.org/10.1161/circ.132.suppl_3.15370

Copeland-Halperin RS; Baber U; Rajamanickam A; Aquino M; Roy S; Kovacic JC; Moreno P; Krishnan P; Sweeny J; Mehran R; Dangas G; Kini AS; Sharma SK, 2015, 'Abstract 16973: Prevalence, Determinants, and Impact of Target Lesion Calcification in Patients Undergoing Percutaneous Coronary Intervention With Newer Generation Drug Eluting Stents: Findings From a Large Multiethnic Registry', Circulation, 132, http://dx.doi.org/10.1161/circ.132.suppl_3.16973

Alicea D; Hekmaty S; Rodriguez DT; Bhandari P; Yang DK; Jeong D; Kovacic JC; Bjorkegren JL; Badimon JJ; Weber T; Hajjar RJ; Fuster V; Giannarelli C, 2015, 'Abstract 18340: Alternatively Spliced Tissue Factor Promotes Atherosclerosis by Increasing Foam Cell Formation via LOX-1 and SR-A1 up-regulation', Circulation, 132, http://dx.doi.org/10.1161/circ.132.suppl_3.18340

Senguttuvan NB; Ellozy S; Tejani F; Kovacic J; Kini AS; Sharma SK; Dangas GD, 2015, 'TAVR Through Heavily Calcified Aorta Following Atheroma Retrieval with the "elevator" Technique', Journal of Invasive Cardiology, 27, pp. E216 - E219

Christodoulidis G; Yu J; Kini A; Dangas GD; Baber U; Melissa A; Sartori S; Theodoropoulos K; Bhat A; Kovacic J; Moreno P; Krishnan P; Mehran R; Sharma S, 2015, 'Gender-specific outcomes after balloon aortic valvuloplasty: Inhospital and long-term outcomes', American Heart Journal, 170, pp. 180 - 186, http://dx.doi.org/10.1016/j.ahj.2015.03.013

Kovacic JC, 2015, 'Unlocking the many secrets of noncoding RNA', Journal of the American College of Cardiology, 65, pp. 2538 - 2541, http://dx.doi.org/10.1016/j.jacc.2015.04.014

Back to profile page