By Dr Jason Ciril Kovacic

Journal articles

Beyhoff N; Cao D; Mehran R; Dangas G; Baber U; Sartori S; Blum M; Roumeliotis A; Chandiramani R; Goel R; Zhang Z; Kovacic J; Krishnan P; Barman N; Kapur V; Sweeny J; Sharma SK; Kini A, 2020, 'Prognostic Impact of High-Sensitivity C-Reactive Protein in Patients Undergoing Percutaneous Coronary Intervention According to BMI', Jacc Cardiovascular Interventions, 13, pp. 2882 - 2892, http://dx.doi.org/10.1016/j.jcin.2020.09.024

Trivieri MG; Spagnolo P; Birnie D; Liu P; Drake W; Kovacic JC; Baughman R; Fayad ZA; Judson MA, 2020, 'Challenges in Cardiac and Pulmonary Sarcoidosis: JACC State-of-the-Art Review', Journal of the American College of Cardiology, 76, pp. 1878 - 1901, http://dx.doi.org/10.1016/j.jacc.2020.08.042

Ma L; Chandel N; Ermel R; Sukhavasi K; Hao K; Ruusalepp A; Björkegren JLM; Kovacic JC, 2020, 'Multiple independent mechanisms link gene polymorphisms in the region of ZEB2 with risk of coronary artery disease', Atherosclerosis, 311, pp. 20 - 29, http://dx.doi.org/10.1016/j.atherosclerosis.2020.08.013

Aoi S; Baber U; Kovacic JC; Mehran R; Aquino M; Dangas G; Sweeny J; Vijay P; Shah S; Barman N; Moreno P; Kini AS; Sharma SK, 2020, 'Combined and independent impact of coronary artery calcification and inflammation on risk for adverse cardiovascular events after percutaneous coronary intervention: Results from a large single-center registry', Catheterization and Cardiovascular Interventions, 96, pp. E278 - E286, http://dx.doi.org/10.1002/ccd.28784

Plitt A; Claessen BE; Sartori S; Baber U; Chandrasekhar J; Aquino M; Vijay P; Elsayed S; Kovacic JC; Sweeny J; Barman N; Moreno P; Krishnan P; Demopoulos A; Dangas G; Kini AS; Mehran R; Sharma SK, 2020, 'Impact of stent diameter on outcomes following percutaneous coronary intervention with second-generation drug-eluting stents: Results from a large single-center registry', Catheterization and Cardiovascular Interventions, 96, pp. 558 - 564, http://dx.doi.org/10.1002/ccd.28488

Chandrasekhar J; Dangas G; Baber U; Sartori S; Qadeer A; Aquino M; Vogel B; Faggioni M; Vijay P; Claessen BE; Goel R; Moreno P; Krishnan P; Kovacic JC; Kini A; Mehran R; Sharma S, 2020, 'Impact of insulin treated and non-insulin-treated diabetes compared to patients without diabetes on 1-year outcomes following contemporary PCI', Catheterization and Cardiovascular Interventions, 96, pp. 298 - 308, http://dx.doi.org/10.1002/ccd.28841

Tang GHL; Lerakis S; Kini A; Khan JM; Kovacic JC, 2020, '4-Dimensional Transesophageal Echocardiographic Guidance During TAVR With BASILICA', Jacc Cardiovascular Imaging, 13, pp. 1601 - 1614, http://dx.doi.org/10.1016/j.jcmg.2019.11.022

Tang GHL; Zaid S; Fuchs A; Yamabe T; Yazdchi F; Gupta E; Ahmad H; Kofoed KF; Goldberg JB; Undemir C; Kaple RK; Shah PB; Kaneko T; Lansman SL; Khera S; Kovacic JC; Dangas GD; Lerakis S; Sharma SK; Kini A; Adams DH; Khalique OK; Hahn RT; Søndergaard L; George I; Kodali SK; De Backer O; Leon MB; Bapat VN, 2020, 'Alignment of Transcatheter Aortic-Valve Neo-Commissures (ALIGN TAVR): Impact on Final Valve Orientation and Coronary Artery Overlap', Jacc Cardiovascular Interventions, 13, pp. 1030 - 1042, http://dx.doi.org/10.1016/j.jcin.2020.02.005

del Monte-Nieto G; Fischer JW; Gorski DJ; Harvey RP; Kovacic JC, 2020, 'Basic Biology of Extracellular Matrix in the Cardiovascular System, Part 1/4: JACC Focus Seminar', Journal of the American College of Cardiology, 75, pp. 2169 - 2188, http://dx.doi.org/10.1016/j.jacc.2020.03.024

Frangogiannis NG; Kovacic JC, 2020, 'Extracellular Matrix in Ischemic Heart Disease, Part 4/4: JACC Focus Seminar', Journal of the American College of Cardiology, 75, pp. 2219 - 2235, http://dx.doi.org/10.1016/j.jacc.2020.03.020

Barallobre-Barreiro J; Loeys B; Mayr M; Rienks M; Verstraeten A; Kovacic JC, 2020, 'Extracellular Matrix in Vascular Disease, Part 2/4: JACC Focus Seminar', Journal of the American College of Cardiology, 75, pp. 2189 - 2203, http://dx.doi.org/10.1016/j.jacc.2020.03.018

Díez J; González A; Kovacic JC, 2020, 'Myocardial Interstitial Fibrosis in Nonischemic Heart Disease, Part 3/4: JACC Focus Seminar', Journal of the American College of Cardiology, 75, pp. 2204 - 2218, http://dx.doi.org/10.1016/j.jacc.2020.03.019

Zaid S; Sengupta A; Okoli K; Tsoi M; Khan A; Ahmad H; Goldberg JB; Undemir C; Rozenshtein A; Patel N; Khan M; Gupta E; Kovacic J; Lansman SL; Dangas GD; Sharma SK; Kini A; Tang GHL, 2020, 'Novel Anatomic Predictors of New Persistent Left Bundle Branch Block After Evolut Transcatheter Aortic Valve Implantation', American Journal of Cardiology, 125, pp. 1222 - 1229, http://dx.doi.org/10.1016/j.amjcard.2020.01.008

Santini MP; Malide D; Hoffman G; Pandey G; D'Escamard V; Nomura-Kitabayashi A; Rovira I; Kataoka H; Ochando J; Harvey RP; Finkel T; Kovacic JC, 2020, 'Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner', Cell Reports, 30, pp. 555 - 570.e7, http://dx.doi.org/10.1016/j.celrep.2019.12.045

Fernandez-Jimenez R; Jaslow R; Bansilal S; Diaz-Munoz R; Fatterpekar M; Santana M; Clarke-Littman A; Latina J; Soto AV; Hill CA; Al-Kazaz M; Samtani R; Vedanthan R; Giannarelli C; Kovacic JC; Bagiella E; Kasarskis A; Fayad ZA; Fuster V, 2020, 'Different Lifestyle Interventions in Adults From Underserved Communities: The FAMILIA Trial', Journal of the American College of Cardiology, 75, pp. 42 - 56, http://dx.doi.org/10.1016/j.jacc.2019.10.021

Olin JW; Di Narzo AF; D'Escamard V; Kadian-Dodov D; Cheng H; Georges A; King A; Thomas A; Barwari T; Michelis KC; Bouchareb R; Bander E; Anyanwu A; Stelzer P; Filsoufi F; Florman S; Civelek M; Debette S; Jeunemaitre X; Björkegren JLM; Mayr M; Bouatia-Naji N; Hao K; Kovacic JC, 2020, 'A plasma proteogenomic signature for fibromuscular dysplasia', Cardiovascular Research, 116, pp. 63 - 77, http://dx.doi.org/10.1093/cvr/cvz219

Sengupta A; Alexis SL; Kovacic JC; Tang GHL, 2020, 'Current challenges in TAVI: Neo-commissural alignment to mimic more physiologic valve implantation', Vessel Plus, 4, http://dx.doi.org/10.20517/2574-1209.2020.55

Haider N; Boscá L; Zandbergen HR; Kovacic JC; Narula N; González-Ramos S; Fernandez-Velasco M; Agrawal S; Paz-García M; Gupta S; DeLeon-Pennell K; Fuster V; Ibañez B; Narula J, 2019, 'Transition of Macrophages to Fibroblast-Like Cells in Healing Myocardial Infarction', Journal of the American College of Cardiology, 74, pp. 3124 - 3135, http://dx.doi.org/10.1016/j.jacc.2019.10.036

Fatkin D; Huttner IG; Kovacic JC; Seidman JG; Seidman CE, 2019, 'Precision Medicine in the Management of Dilated Cardiomyopathy: JACC State-of-the-Art Review', Journal of the American College of Cardiology, 74, pp. 2921 - 2938, http://dx.doi.org/10.1016/j.jacc.2019.10.011

Glicksberg BS; Amadori L; Akers NK; Sukhavasi K; Franzén O; Li L; Belbin GM; Ayers KL; Shameer K; Badgeley MA; Johnson KW; Readhead B; Darrow BJ; Kenny EE; Betsholtz C; Ermel R; Skogsberg J; Ruusalepp A; Schadt EE; Dudley JT; Ren H; Kovacic JC; Giannarelli C; Li SD; Björkegren JLM; Chen R, 2019, 'Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits (BMC Medical Genomics DOI: 10.1186/s12920-019-0542-3)', BMC Medical Genomics, 12, http://dx.doi.org/10.1186/s12920-019-0573-9

Hulshoff MS; Del Monte-Nieto G; Kovacic J; Krenning G, 2019, 'Non-coding RNA in endothelial-to-mesenchymal transition', Cardiovascular Research, 115, pp. 1716 - 1731, http://dx.doi.org/10.1093/cvr/cvz211

Tadros RO; Tang GHL; Barnes HJ; Mousavi I; Kovacic JC; Faries P; Olin JW; Marin ML; Adams DH, 2019, 'Optimal Treatment of Uncomplicated Type B Aortic Dissection: JACC Review Topic of the Week', Journal of the American College of Cardiology, 74, pp. 1494 - 1504, http://dx.doi.org/10.1016/j.jacc.2019.07.063

Glicksberg BS; Amadori L; Akers NK; Sukhavasi K; Franzén O; Li L; Belbin GM; Akers KL; Shameer K; Badgeley MA; Johnson KW; Readhead B; Darrow BJ; Kenny EE; Betsholtz C; Ermel R; Skogsberg J; Ruusalepp A; Schadt EE; Dudley JT; Ren H; Kovacic JC; Giannarelli C; Li SD; Björkegren JLM; Chen R, 2019, 'Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits', BMC Medical Genomics, 12, http://dx.doi.org/10.1186/s12920-019-0542-3

Tang GHL; Zaid S; Gupta E; Ahmad H; Khan A; Kovacic JC; Lansman SL; Dangas GD; Sharma SK; Kini A, 2019, 'Feasibility of Repeat TAVR After SAPIEN 3 TAVR: A Novel Classification Scheme and Pilot Angiographic Study', Jacc Cardiovascular Interventions, 12, pp. 1290 - 1292, http://dx.doi.org/10.1016/j.jcin.2019.02.020

Tang GHL; Zaid S; Gupta E; Ahmad H; Patel N; Khan M; Khan A; Kovacic JC; Lansman SL; Dangas GD; Sharma SK; Kini A, 2019, 'Impact of Initial Evolut Transcatheter Aortic Valve Replacement Deployment Orientation on Final Valve Orientation and Coronary Reaccess: A Pilot Study', Circulation Cardiovascular Interventions, 12, http://dx.doi.org/10.1161/CIRCINTERVENTIONS.119.008044

Zeng L; Talukdar HA; Koplev S; Giannarelli C; Ivert T; Gan LM; Ruusalepp A; Schadt EE; Kovacic JC; Lusis AJ; Michoel T; Schunkert H; Björkegren JLM, 2019, 'Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease', Journal of the American College of Cardiology, 73, pp. 2946 - 2957, http://dx.doi.org/10.1016/j.jacc.2019.03.520

Mahajan AM; Claessen BE; Chandrasekhar J; Sartori S; Aquino M; Baber U; Dangas G; Kovacic JC; Krishnan P; Moreno P; Sweeny J; Barman N; Vijay P; Kini A; Mehran R; Sharma S, 2019, 'Outcomes by Gender and Ethnicity After Percutaneous Coronary Intervention', American Journal of Cardiology, 123, pp. 1941 - 1948, http://dx.doi.org/10.1016/j.amjcard.2019.03.019

Guedeney P; Claessen BE; Baber U; Camaj A; Sorrentino S; Aquino M; Blum M; Chandiramani R; Goel R; Elsayed S; Kovacic JC; Sweeny J; Barman N; Moreno P; Dangas GD; Kini A; Sharma S; Mehran R, 2019, 'Temporal Trends in Statin Prescriptions and Residual Cholesterol Risk in Patients With Stable Coronary Artery Disease Undergoing Percutaneous Coronary Intervention', American Journal of Cardiology, 123, pp. 1788 - 1795, http://dx.doi.org/10.1016/j.amjcard.2019.03.005

Guedeney P; Claessen BE; Kalkman DN; Aquino M; Sorrentino S; Giustino G; Farhan S; Vogel B; Sartori S; Montalescot G; Sweeny J; Kovacic JC; Krishnan P; Barman N; Dangas G; Kini A; Baber U; Sharma S; Mehran R, 2019, 'Residual Inflammatory Risk in Patients With Low LDL Cholesterol Levels Undergoing Percutaneous Coronary Intervention', Journal of the American College of Cardiology, 73, pp. 2401 - 2409, http://dx.doi.org/10.1016/j.jacc.2019.01.077

Fernandez-Jimenez R; Jaslow R; Bansilal S; Santana M; Diaz-Munoz R; Latina J; Soto AV; Vedanthan R; Al-Kazaz M; Giannarelli C; Kovacic JC; Bagiella E; Kasarskis A; Fayad ZA; Hajjar RJ; Fuster V, 2019, 'Child Health Promotion in Underserved Communities: The FAMILIA Trial', Journal of the American College of Cardiology, 73, pp. 2011 - 2021, http://dx.doi.org/10.1016/j.jacc.2019.01.057

Zhang Z; Cheng H; Hong X; DI Narzo AF; Franzen O; Peng S; Ruusalepp A; Kovacic JC; Bjorkegren JLM; Wang X; Hao K, 2019, 'EnsembleCNV: An ensemble machine learning algorithm to identify and genotype copy number variation using SNP array data', Nucleic Acids Research, 47, http://dx.doi.org/10.1093/nar/gkz068

Gornik HL; Persu A; Adlam D; Aparicio LS; Azizi M; Boulanger M; Bruno RM; de Leeuw P; Fendrikova-Mahlay N; Froehlich J; Ganesh SK; Gray BH; Jamison C; Januszewicz A; Jeunemaitre X; Kadian-Dodov D; Kim ESH; Kovacic JC; Mace P; Morganti A; Sharma A; Southerland AM; Touzé E; van der Niepen P; Wang J; Weinberg I; Wilson S; Olin JW; Plouin PF, 2019, 'First International Consensus on the diagnosis and management of fibromuscular dysplasia', Vascular Medicine United Kingdom, 24, pp. 164 - 189, http://dx.doi.org/10.1177/1358863X18821816

Kovacic JC; Dimmeler S; Harvey RP; Finkel T; Aikawa E; Krenning G; Baker AH, 2019, 'Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review', Journal of the American College of Cardiology, 73, pp. 190 - 209, http://dx.doi.org/10.1016/j.jacc.2018.09.089

Adlam D; Olson TM; Combaret N; Kovacic JC; Iismaa SE; Al-Hussaini A; O'Byrne MM; Bouajila S; Georges A; Mishra K; Braund PS; d'Escamard V; Huang S; Margaritis M; Nelson CP; de Andrade M; Kadian-Dodov D; Welch CA; Mazurkiewicz S; Jeunemaitre X; Wong CMY; Giannoulatou E; Sweeting M; Muller D; Wood A; McGrath-Cadell L; Fatkin D; Dunwoodie SL; Harvey R; Holloway C; Empana JP; Jouven X; Olin JW; Gulati RMD; Tweet MS; Hayes SN; Samani NJ; Graham RM; Motreff P; Bouatia-Naji N; Nikpay M; Goel A; Won HH; Hall LM; Willenborg C; Kanoni S; Saleheen D; Kyriakou T; Hopewell JC; Webb TR; Zeng L; Dehghan A; Alver M; Armasu SM; Auro K; Bjonnes A; Chasman DI; Chen S; Ford I; Franceschini N; Gieger C; Grace C; Gustafsson S; Huang J; Hwang SJ; Kim YK; Kleber ME; Lau KW; Lu X; Lu Y; Lyytikäinen LP; Mihailov E; Morrison A; Pervjakova N; Qu L; Rose LM; Salfati E; Saxena R; Scholz M; Smith AV; Tikkanen E; Uitterlinden A; Yang X; Zhang W; Zhao W; de Andrade M; de Vries PS; van Zuydam NR; Anand SS; Bertram L; Beutner F; Dedoussis G; Frossard P; Gauguier D; Goodall AH; Gottesman O; Haber M; Han BG; Huang J, 2019, 'Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection', Journal of the American College of Cardiology, 73, pp. 58 - 66, http://dx.doi.org/10.1016/j.jacc.2018.09.085

Gornik HL; Persu A; Adlam D; Aparicio LS; Azizi M; Boulanger M; Bruno RM; De Leeuw P; Fendrikova-Mahlay N; Froehlich J; Ganesh SK; Gray BH; Jamison C; Januszewicz A; Jeunemaitre X; Kadian-Dodov D; Kim ESH; Kovacic JC; MacE P; Morganti A; Sharma A; Southerland AM; Touzé E; Van Der Niepen P; Wang J; Weinberg I; Wilson S; Olin JW; Plouin PF, 2019, 'First international consensus on the diagnosis and management of fibromuscular dysplasia', Journal of Hypertension, 37, pp. 229 - 252, http://dx.doi.org/10.1097/HJH.0000000000002019

Frades I; Readhead B; Amadori L; Koplev S; Talukdar HA; Crane HM; Crane PK; Kovacic JC; Dudley JT; Giannarelli C; Björkegren JLM; Peter I, 2019, 'Systems pharmacology identifies an arterial wall regulatory gene network mediating coronary artery disease side effects of antiretroviral therapy', Circulation Genomic and Precision Medicine, 12, pp. 262 - 272, http://dx.doi.org/10.1161/CIRCGEN.118.002390

Guedeney P; Baber U; Claessen B; Aquino M; Camaj A; Sorrentino S; Vogel B; Farhan S; Faggioni M; Chandrasekhar J; Kalkman DN; Kovacic JC; Sweeny J; Barman N; Moreno P; Vijay P; Shah S; Dangas G; Kini A; Sharma S; Mehran R, 2019, 'Temporal trends, determinants, and impact of high-intensity statin prescriptions after percutaneous coronary intervention: Results from a large single-center prospective registry', American Heart Journal, 207, pp. 10 - 18, http://dx.doi.org/10.1016/j.ahj.2018.09.001

Price LZ; Tang GH; Faries PL; Kovacic JC; McKinsey JF; Prakash K; Tadros RO, 2019, 'The epidemiology, pathophysiology, and novel treatment of calcific arterial disease', Surgical Technology International, 34, pp. 1 - 8

, 2019, 'Correction', Journal of the American College of Cardiology, 74, pp. 481 - 482, http://dx.doi.org/10.1016/j.jacc.2019.06.009

Price LZ; Faries PL; McKinsey JF; Krishnan P; Tang GHL; Kovacic JC; Han DK; Tadros RO, 2019, 'Shockwave Lithotripsy Facilitates Large-Bore Vascular Access Through Calcified Arteries', Journal of Vascular Surgery, 70, pp. e23, http://dx.doi.org/10.1016/j.jvs.2019.06.020

Kalkman DN; Aquino M; Claessen BE; Baber U; Guedeney P; Sorrentino S; Vogel B; De Winter RJ; Sweeny J; Kovacic JC; Shah S; Vijay P; Barman N; Kini A; Sharma S; Dangas GD; Mehran R, 2018, 'Residual inflammatory risk and the impact on clinical outcomes in patients after percutaneous coronary interventions', European Heart Journal, 39, pp. 4101 - 4108, http://dx.doi.org/10.1093/eurheartj/ehy633

Peng S; Deyssenroth MA; Di Narzo AF; Cheng H; Zhang Z; Lambertini L; Rusualepp A; Kovacic JC; Bjorkegren JLM; Marsit CJ; Chen J; Hao K, 2018, 'Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity', Plos Genetics, 14, http://dx.doi.org/10.1371/journal.pgen.1007799

Robson PM; Trivieri MG; Karakatsanis NA; Padilla M; Abgral R; Dweck MR; Kovacic JC; Fayad ZA, 2018, 'Correction of respiratory and cardiac motion in cardiac PET/MR using MR-based motion modeling', Physics in Medicine and Biology, 63, http://dx.doi.org/10.1088/1361-6560/aaea97

Fernandez-Jimenez R; Jaslow R; Bansilal S; Santana M; Diaz-Munoz R; Trabal G; Latina J; Soto AV; Vedanthan R; Giannarelli C; Kovacic J; Bagiella E; Kasarskis A; Fayad Z; Hajjar RJ; Fuster V, 2018, 'Abstract 16663: Child Health Promotion in Underserved Communities: Primary Results From the Cluster Randomized FAMILIA Trial', Circulation, 138, http://dx.doi.org/10.1161/circ.138.suppl_1.16663

Williams JW; Giannarelli C; Rahman A; Randolph GJ; Kovacic JC, 2018, 'Macrophage Biology, Classification, and Phenotype in Cardiovascular Disease: JACC Macrophage in CVD Series (Part 1)', Journal of the American College of Cardiology, 72, pp. 2166 - 2180, http://dx.doi.org/10.1016/j.jacc.2018.08.2148

Moore KJ; Koplev S; Fisher EA; Tabas I; Björkegren JLM; Doran AC; Kovacic JC, 2018, 'Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)', Journal of the American College of Cardiology, 72, pp. 2181 - 2197, http://dx.doi.org/10.1016/j.jacc.2018.08.2147

Fayad ZA; Swirski FK; Calcagno C; Robbins CS; Mulder W; Kovacic JC, 2018, 'Monocyte and Macrophage Dynamics in the Cardiovascular System: JACC Macrophage in CVD Series (Part 3)', Journal of the American College of Cardiology, 72, pp. 2198 - 2212, http://dx.doi.org/10.1016/j.jacc.2018.08.2150

Lavine KJ; Pinto AR; Epelman S; Kopecky BJ; Clemente-Casares X; Godwin J; Rosenthal N; Kovacic JC, 2018, 'The Macrophage in Cardiac Homeostasis and Disease: JACC Macrophage in CVD Series (Part 4)', Journal of the American College of Cardiology, 72, pp. 2213 - 2230, http://dx.doi.org/10.1016/j.jacc.2018.08.2149

Camaj A; Giustino G; Baber U; Aquino M; Kalkman D; Shah S; Barman N; Vijay P; Kovacic J; Sorrentino S; Sweeny J; Dangas G; Kini A; Sharma S; Mehran R, 2018, 'P1652Effect of systemic inflammation and coronary artery disease complexity on outcomes after percutaneous coronary intervention', European Heart Journal, 39, pp. ehy565.p1652, http://dx.doi.org/10.1093/eurheartj/ehy565.p1652

Von Scheidt M; Zhao Y; De Aguiar Vallim TQ; Che N; Franzen O; Kurt Z; Yamamoto M; Edwards PA; Ruusalepp A; Kovacic J; Bjorkegren JLM; Lusis AJ; Yang X; Schunkert H, 2018, 'P1844The transcription factor MAFF regulates an atherosclerosis relevant gene network', European Heart Journal, 39, pp. ehy565.p1844, http://dx.doi.org/10.1093/eurheartj/ehy565.p1844

Back to profile page