Select Publications
Preprints
, 2021, HeterozygousKCNH2variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology, http://dx.doi.org/10.1101/2021.02.02.427891
, 2021, Structural Basis for Rapid Voltage Dependent Inactivation of HERG Potassium Channels, http://dx.doi.org/10.21203/rs.3.rs-1105661/v1
, 2020, High-throughput discovery of trafficking-deficient variants in the cardiac potassium channelKCNH2: Deep mutational scan ofKCNH2trafficking, http://dx.doi.org/10.1101/2020.02.17.952606
, 2020, Arrhythmogenesis as the failure of repolarization, http://dx.doi.org/10.1101/2020.07.02.185694
, 2019, Protocol-dependent differences in IC50 values measured in hERG assays occur in a predictable way and can be used to quantify state preference of drug binding, http://dx.doi.org/10.1101/534867
, Translating the Measurement of Herg Kinetics and Drug Block for Cipa to a High Throughput Platform, http://dx.doi.org/10.2139/ssrn.4065593
Other
, 2016, An 'alternans' way to quantify arrhythmogenic substrates, http://dx.doi.org/10.1113/JP271838
, 2015, 'Shooting gallery' for membrane proteins provides new insights into complexities of their function and structural dynamics, http://dx.doi.org/10.1113/jphysiol.2014.286559
, 2010, Oxidative stress fine-tunes the dance of hERG K+ channels, Blackwell Publishing Ltd, http://dx.doi.org/10.1113/jphysiol.2010.195651
, 2006, Reply from Jamie I. Vandenberg, Adam P. Hill, Terence J. Campbell, Catherine E. Clarke [2], http://dx.doi.org/10.1113/jphysiol.2006.577102
, 2005, Erratum: Inherited cardiac arrhythmia syndromes: What have they taught us about arrhythmias and anti-arrhythmic therapy? (Clinical and Experimental Pharmacology and Physiology (2004) 31 (906-912))