Select Publications
Book Chapters
, 2014, 'Voltage-Gated Potassium Channels (Kv10-Kv12)', in Reference Module in Biomedical Research, http://dx.doi.org/10.1016/B978-0-12-801238-3.04809-1
, 1999, 'Genetic Engineering and Cardiac Ion Channels', in Developments in Cardiovascular Medicine, Springer Netherlands, pp. 171 - 178, http://dx.doi.org/10.1007/978-94-015-9321-2_16
Journal articles
, 2026, 'Correction: Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia (Stem Cell Research & Therapy, (2023), 14, 1, (183), 10.1186/s13287-023-03405-5)', Stem Cell Research and Therapy, 17, http://dx.doi.org/10.1186/s13287-026-04942-5
, 2026, 'MultiECGNet: Evaluation of a Deep-Learning Ensemble Method for Image-Based 12-Lead Electrocardiographic Detection of Atrial Fibrillation', Cjc Open, 8, pp. 1074 - 1087, http://dx.doi.org/10.1016/j.cjco.2026.03.022
, 2026, 'Wearable Cardiac Devices as Windows Into Physiological Decline: A Review of Digital Biomarkers in the Prevention, Detection, and Management of Cardiogeriatric Frailty', Heart Lung and Circulation, 35, pp. 745 - 753, http://dx.doi.org/10.1016/j.hlc.2025.12.017
, 2026, 'National Funding for Cardiac Arrest Research in Australia: An Analysis of Competitive Grant Schemes', Heart Lung and Circulation, 35, pp. 492 - 502, http://dx.doi.org/10.1016/j.hlc.2025.11.013
, 2026, 'Increased yield of genetic diagnoses in inherited heart diseases using expanded genome and RNA-splicing analyses', Genetics in Medicine, 28, http://dx.doi.org/10.1016/j.gim.2025.101626
, 2026, 'KCNH2 Duplication Variant (c.2164_2181dup) Associated With Sudden Cardiac Death in a Family With Congenital Long QT Syndrome', Canadian Journal of Cardiology, http://dx.doi.org/10.1016/j.cjca.2026.03.020
, 2026, 'Antiarrhythmic Effects of Co-Application of mDivi-1 and Teriflunomide in an iPSC Model of Inflammation Driven Atrial Fibrillation', Heart Lung and Circulation, 35, pp. s566, http://dx.doi.org/10.1016/j.hlc.2026.07.880
, 2026, 'BPS2026 – Flipping gating polarity in hERG by uncoupling the S4-S5 linker from the inner bundle gate', Biophysical Journal, 125, pp. 79a - 79a, http://dx.doi.org/10.1016/j.bpj.2025.11.676
, 2026, 'Investigating inflammation induced new onset atrial fibrillation in 2D and 3D stem cell models', Journal of Molecular and Cellular Cardiology Plus, 15, pp. 100626 - 100626, http://dx.doi.org/10.1016/j.jmccpl.2025.100626
, 2026, 'Molecular Basis for state-dependent drug block of Kv11.1 (HERG) potassium channels', Molecular Pharmacology, pp. 100150, http://dx.doi.org/10.1016/j.molpha.2026.100150
, 2026, 'Sudden Cardiac Arrest in NSW, Australia: A Data Linkage Study', Heart Lung and Circulation, 35, pp. s457 - s458, http://dx.doi.org/10.1016/j.hlc.2026.07.690
, 2025, 'Titin-related familial dilated cardiomyopathy: factors associated with disease onset', European Heart Journal, 46, pp. 5240 - 5257, http://dx.doi.org/10.1093/eurheartj/ehaf380
, 2025, 'Automated patch clamp data improve variant classification and penetrance stratification for SCN5A–Brugada syndrome', European Heart Journal, pp. 1 - 15, http://dx.doi.org/10.1093/eurheartj/ehaf874
, 2025, 'Independent derivations of the axis of arrhythmia for predicting drug-induced torsades de pointes', British Journal of Pharmacology, 182, pp. 4299 - 4313, http://dx.doi.org/10.1111/bph.70078
, 2025, 'Calibrated Functional Data Decrease Clinical Uncertainty for KCNH2 -Related Long-QT Syndrome', Circulation Genomic and Precision Medicine, 18, pp. e005204, http://dx.doi.org/10.1161/CIRCGEN.125.005204
, 2025, 'An Expert Opinion on the Management of Frailty in Heart Failure from the Australian Cardiovascular Alliance National Taskforce', Heart Lung and Circulation, 34, pp. 693 - 703, http://dx.doi.org/10.1016/j.hlc.2025.01.012
, 2025, 'Combined RNA Splicing and Patch-Clamp Analysis Reveal Pathogenicity of Splice-Altering Variants in KCNH2 -Related LQTS', Circulation Genomic and Precision Medicine, 18, pp. e004966, http://dx.doi.org/10.1161/CIRCGEN.124.004966
, 2025, 'Cardiac arrest in Australia: a call to action', Australian Health Review, 49, http://dx.doi.org/10.1071/AH25034
, 2025, 'Cardiovascular Workforce Sustainability Sector Consultation: Recommendations From an Australian Stakeholder Summit', Heart Lung and Circulation, 34, pp. 95 - 101, http://dx.doi.org/10.1016/j.hlc.2024.10.012
, 2025, 'Mechanistic Insights and Knowledge Gaps in the Effects of Radiation Therapy on Cardiac Arrhythmias', International Journal of Radiation Oncology Biology Physics, 121, pp. 75 - 89, http://dx.doi.org/10.1016/j.ijrobp.2024.08.040
, 2025, 'National funding for cardiac arrest research in Australia: an analysis of competitive grant schemes', Heart, Lung and Circulation, 34, pp. S571 - S573, http://dx.doi.org/10.1016/j.hlc.2025.06.750
, 2025, 'National funding for cardiac arrest research in Australia: an analysis of competitive grant schemes', EUROPEAN HEART JOURNAL, 46, http://dx.doi.org/10.1093/eurheartj/ehaf784.603
, 2024, 'Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve KCNH2-LQTS Variant Classification and Cardiac Event Risk Stratification', Circulation, 150, pp. 1869 - 1881, http://dx.doi.org/10.1161/CIRCULATIONAHA.124.069828
, 2024, 'Potassium dependent structural changes in the selectivity filter of HERG potassium channels', Nature Communications, 15, http://dx.doi.org/10.1038/s41467-024-51208-w
, 2024, 'A Call to Action to Improve Cardiac Arrest Outcomes: A Report From the National Summit for Cardiac Arrest', Heart Lung and Circulation, 33, pp. 1507 - 1522, http://dx.doi.org/10.1016/j.hlc.2024.09.001
, 2024, 'Research Priorities for Atrial Fibrillation in Australia: A Statement From the Australian Cardiovascular Alliance Clinical Arrhythmia Theme', Heart Lung and Circulation, 33, pp. 1523 - 1532, http://dx.doi.org/10.1016/j.hlc.2024.08.008
, 2024, 'Multisite Validation of a Functional Assay to Adjudicate SCN5A Brugada Syndrome–Associated Variants', Circulation Genomic and Precision Medicine, 17, pp. e004569, http://dx.doi.org/10.1161/CIRCGEN.124.004569
, 2024, 'Reduced connexin-43 expression, slow conduction and repolarisation dispersion in a model of hypertrophic cardiomyopathy', Dmm Disease Models and Mechanisms, 17, http://dx.doi.org/10.1242/dmm.050407
, 2024, 'Altered left atrial metrics in patients with cryptogenic stroke: A systematic review and meta-analysis', European Journal of Clinical Investigation, 54, http://dx.doi.org/10.1111/eci.14175
, 2024, 'Clinical interpretation of KCNH2 variants using a robust PS3/BS3 functional patch-clamp assay', Human Genetics and Genomics Advances, 5, pp. 100270, http://dx.doi.org/10.1016/j.xhgg.2024.100270
, 2024, 'The real-world incidence of severe QT prolongation in patients taking antipsychotic drugs', Heart Rhythm, 21, pp. 329 - 330, http://dx.doi.org/10.1016/j.hrthm.2023.11.012
, 2024, 'A multitiered analysis platform for genome sequencing: Design and initial findings of the Australian Genomics Cardiovascular Disorders Flagship', Genetics in Medicine Open, 2, http://dx.doi.org/10.1016/j.gimo.2024.101842
, 2024, 'Integration of validated functional evidence to support the pathogenicity of KCNH2 variants', Genetics in Medicine Open, 2, http://dx.doi.org/10.1016/j.gimo.2024.101868
, 2024, 'BS-469619-003 GRANULAR VARIANT-SPECIFIC FEATURES IMPROVE KCNH2-LONG QT SYNDROME RISK STRATIFICATION', Heart Rhythm, 21, pp. S52 - S52, http://dx.doi.org/10.1016/j.hrthm.2024.03.363
, 2023, 'Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology', , 12, http://dx.doi.org/10.7554/elife.90027.3
, 2023, 'Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia', Stem Cell Research and Therapy, 14, http://dx.doi.org/10.1186/s13287-023-03405-5
, 2023, 'Structural basis of promiscuous substrate transport by Organic Cation Transporter 1', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-42086-9
, 2023, 'Action Potential Morphology Accurately Predicts Proarrhythmic Risk for Drugs with Potential to Prolong Cardiac Repolarization', Circulation Arrhythmia and Electrophysiology, 16, pp. 399 - 410, http://dx.doi.org/10.1161/CIRCEP.122.011574
, 2023, 'Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance', Human Molecular Genetics, 32, pp. 1072 - 1082, http://dx.doi.org/10.1093/hmg/ddac261
, 2023, 'The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review', Annals of Noninvasive Electrocardiology, 28, http://dx.doi.org/10.1111/anec.13015
, 2023, 'Development of automated patch clamp assays to overcome the burden of variants of uncertain significance in inheritable arrhythmia syndromes.', Front Physiol, 14, pp. 1294741, http://dx.doi.org/10.3389/fphys.2023.1294741
, 2022, 'Don't Turn Off the Tap! The Importance of Discovery Science to the Australian Cardiovascular Sector and Improving Clinical Outcomes Into the Future', Heart Lung and Circulation, 31, pp. 1321 - 1332, http://dx.doi.org/10.1016/j.hlc.2022.06.669
, 2022, 'High throughput measurement of hERG drug block kinetics using the CiPA dynamic protocol', Journal of Pharmacological and Toxicological Methods, 117, http://dx.doi.org/10.1016/j.vascn.2022.107192
, 2022, 'A calibrated functional patch-clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome', American Journal of Human Genetics, 109, pp. 1199 - 1207, http://dx.doi.org/10.1016/j.ajhg.2022.05.002
, 2022, 'A massively parallel assay accurately discriminates between functionally normal and abnormal variants in a hotspot domain of KCNH2', American Journal of Human Genetics, 109, pp. 1208 - 1216, http://dx.doi.org/10.1016/j.ajhg.2022.05.003
, 2022, 'Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation', British Journal of Pharmacology, 179, pp. 2631 - 2646, http://dx.doi.org/10.1111/bph.15757
, 2022, 'The yin and yang of Tbx5 variant effects on sodium channel function', Cardiovascular Research, 118, pp. 929 - 931, http://dx.doi.org/10.1093/cvr/cvac015
, 2022, 'Arrhythmic Phenotypes Are a Defining Feature of Dilated Cardiomyopathy-Associated SCN5A Variants: A Systematic Review', Circulation Genomic and Precision Medicine, 15, pp. E003432, http://dx.doi.org/10.1161/CIRCGEN.121.003432