My central scientific interest has been to understand the genetic architecture of disease. With data from the genome, transcriptome, epigenome and proteome increasing exponentially, robust tools and practices need to be established to analyse this deluge, in particular if to be applied to personalized medicine.
I obtained my PhD from the University of New South Wales and the Victor Chang Cardiac Research Institute in 2013, working with Drs...view more
My central scientific interest has been to understand the genetic architecture of disease. With data from the genome, transcriptome, epigenome and proteome increasing exponentially, robust tools and practices need to be established to analyse this deluge, in particular if to be applied to personalized medicine.
I obtained my PhD from the University of New South Wales and the Victor Chang Cardiac Research Institute in 2013, working with Drs Merridee Wouters and Bruno Gaeta. I then moved to Cold Spring Harbor Laboratory for my postdoctoral training with Dr Jesse Gillis. In 2020, I started my own group at the Garvan-Weizmann Centre for Cellular Genomics at the Garvan Institute of Medical Research.
My Qualifications
Education
2013 - PhD, Victor Chang Cardiac Research Institute and the University of New South Wales, Sydney - Australia
2008 - BE Bioinformatics First Class Honours, University of New South Wales, Sydney – Australia
2008 - BSc Genetics, University of New South Wales, Sydney – Australia
My Research Activities
• Transcriptomics (single-cell and bulk)
• Co-expression
• X-linked disorders
• Sex differences in disease
• Meta-analysis
• Personalized medicine
My Research Supervision
Supervision keywords
Areas of supervision
Broad: Bioinformatics, Genomics and transcriptomics, Computational Biology, Functional Genomics
Biology and disease: Autoimmune disease, X-linked disorders, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), long-COVID, X-chromosome inactivation, sex differences in disease
Methods: Co-expression and network analysis, differential expression analysis, gene set enrichment, candidate disease gene prediction, functional gene analysis, meta-analysis
Data: RNA-seq, single-cell analysis
Currently supervising
Lachlan Gray - eXamining the role of the X chromosome in female autoimmune disease
https://orcid.org/0000-0003-4701-3020